Serial values for hematologic and biochemical analysis after myocardial infarction in rats

( Mi Jin Lee ),( Hyun Jin Tae ),( Ying Hua Li ),( Do Hyeon Yu ),( In Ae Han ),( Seok Won Lee ),( Dong Choon Ahn ),( In Shik Kim ),( Jin Ho Park ) 한국가축위생학회 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction(MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hema-tologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and bioche-mical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery(LMDA) of the left coronary artery was ligated during the progression(day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group(n=24, thoracotomy without LMDA ligation) and the experimental(MI) group(n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell(RBCs), hemoglobin and hematocrit(HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, choles-terol, total creatine kinase(CK) and isoenzyme MB, and lactate dehydrogenase(LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

Serial values for hematologic and biochemical analysis after myocardial infarction in rats

Lee, Mi-Jin,Tae, Hyun-Jin,Li, Ying-Hua,Yu, Do-Hyeon,Han, In-Ae,Lee, Seok-Won,Ahn, Dong-Choon,Kim, In-Shik,Park, Jin-Ho The Korean Society of Veterinary Service 2008 韓國家畜衛生學會誌 Vol.31 No.2

To diagnose acute myocardial infarction (MI), many cardiac markers have been used in hematologic and biochemical analysis, and many studies have been published for hematologic and biochemical analysis associated with human acute MI. However, after occurrence of acute MI, the serial investigation for values in hematologic and biochemical analysis including chronic MI has rarely been performed. To observe the change of the serial values in hematologic and biochemical analysis, we induced artificial MI. The left main descending artery (LMDA) of the left coronary artery was ligated during the progression (day 1, 3, 5, 7, 14 and 30) of MI. Total 66 Sprague-Dawley rats were divided into the sham group (n=24, thoracotomy without LMDA ligation) and the experimental (MI) group (n=42, with LMDA ligation). And all individual in each group was sacrified at day 1, 3, 5, 7, 14 and 30 for the hematologic and biochemical analysis. In comparison of hematologic analysis between the sham and MI groups, the mean values of red blood cell (RBCs), hemoglobin and hematocrit (HCT) showed a steady increase. In biochemical analysis, the mean values of glucose, cholesterol, total creatine kinase (CK) and isoenzyme MB, and lactate dehydrogenase (LDH) were increased in all MI groups compared with the sham groups. The results of this study suggest that early hematologic and biochemical mean values occurred after acute MI are similar to those of human acute MI. In conclusion, we could observe the alterations and serial values in hematologic and biochemical analysis to the extent of chronic status after acute MI.

The Analysis on the Value of Yongsan National Park and its Economic Effect

Chang, In-Seok,Cho, Young-Tae,Lee, Mi-Hong,Park, Shin-Won Land and Housing Institute 2011 LHI journal of land, housing, and urban affairs Vol.2 No.4

This study estimated economic value and benefits of Yongsan National Park, which will be constructed by financial investment of the government and objectively estimated the real value of it by understanding the value of the park from a user's view of the park. For this, the value of Yongsan National Park is divided into using value such as carbon reduction and the function of relieving urban heat island as an environmental material and non-using value based on willingness to pay of the public according to the construction of the park. As a result of the analysis, it was found out that the using value of Yongsan National Park would reach 130 million won up to maximum level of 450 million won per year, and the non-using value was analyzed to be worthy of 2,344 won per capita every month. Besides, economic ripple effect that can be expected in the process of the park construction project was analyzed to be a national policy that creates effect on production inducement of 2.6 trillion won and value added of 809.6 billion won and new jobs for 25,620 persons. Considering the value of Yongsan National Park and the effect of the project based on the result of this study, it was found that it could sufficiently secure the validity of implementing the project compared to the financial investment by the government. Therefore, it must be emphasized that diffusion strategy is necessary for national understanding and for a nation to make it understood its appropriateness widely in respect to the construction of Yongsan National Park for the successful construction of Yongsan National Park and to raise its using value in the future.

연령증가에 따른 혈압요소들의 좌심실비대 및 관동맥질환과의 관련성

박재석,박창규,박미영,박재형,김용현,나진오,신성희,서순용,홍순준,박성미,임홍의,김응주,서홍석,오동주,노영무 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

심근 허혈-재관류 백서 모델에서 mitogen-activated protein kinase 활성화에 대한 α-lipoic acid의 효과

김연경,박은미,최준호,윤경호,유남진,이은미,김남호,정진원,김민선,박병림,오석규 圓光大學校 醫科學硏究所 2006 圓光醫科學 Vol.21 No.1

웹기반의 가축전염병 발생자료 관리시스템(AIMS) 개발

박병호,김석재,황인진,김시동,남향미,위성환 한국농업정보과학회 2003 농업정보과학 Vol.4 No.1

The AIMS(Anima1 Infectious Disease Data Management System) was developed to collect and analyze data on animal infectious disease outbreak (62 diseases). When an animal infectious disease is confirmed at a diagnostic laboratory, the disease outbreak is then reported to the regional government through AIMS. After the regional government confirms the number of animals infected or dead, outbreak date and etc, this information is reported to the Ministry of Agriculture & Forestry and the National Veterinary Research & Quarantine Service through AIMS. The AIMS analyzes the outbreak data and reports the outbreak statistics by region, month and year to them. In addition, the AIMS can identify the farm where there was an outbreak of the animal infectious disease. There are four user roles : 1) Administrator, responsible for the overall operation of the system. 2) Inspector, responsible for confirmation of the animal infectious disease outbreak. 3) Pathologist, responsible for input to an animal infectious disease at first. 4) Gallery, only able to read the outbreak statistics. The AIMS has been implemented using the ASP technology and is operated on the web to allow easy access. The data, middle and presentation tier are based on MS-SQL 2000 server, Microsoft transaction server and Internet Explorer, respectively. The database's stored procedure was used to improve the performance. In addition to above software, the dextupload software is used to upload the files. By using the AIMS, a more accurate statistics for the animal infectious disease outbreak is expected.

접근-회피 성취 목표의 타당도 연구

박영석,성미송 가톨릭대학교 사회과학연구소 2003 社會科學硏究 Vol.19 No.-

본 연구는 개인의 성취 목표 동기가 수행-접근, 수행-회피, 숙달-접근, 그리고 숙달-회피의 네 가지로 구성되어 있다는 2 × 2 성취 목표 모델(Elliot & McGregor, 2001)의 타당도를 검증하기 위해 수행되었다. 국내 기업의 임원 47명과 부장 234명에게 성취 목표를 측정하였고, 그들의 상사 1명, 동료 2명, 그리고 부하 10명이 그들의 리더십을 평가하였다. 공변량구조분석 결과 2 × 2 성취 목표 모델의 구조가 재검증되었고, 이 네 가지 성취 목표의 수렴및 변별 타당도가 함께 측정한 가치, 문제해결 방식, 리더 행동의 상관관계 분석을 통해 확인되었다. 끝으로 2 × 2 성취 목표 모델이 국내에 일반화될 수 있고, 특히 리더의 행동을 예측하는데 유용하게 활용될 수 있다는 점을 논의하였다.

돌산갓 전처리 중의 산도, 항균선 및 색도 변화

박석규,서권일,이상원,조영수,손미혜 동아시아식생활학회 1997 동아시아식생활학회지 Vol.7 No.1

In order to use leaf mustard Dolsan food preservative ingradient, acidity, antimicrobial activity and colors were investigated during pretreatment of leaf mustard Dolsan. pH was remarkably decreased after 8 hours to pretreatment(extracted on shaking) of leaf mustard Dolsan, and no changes were observed after that time. pH of leaf part was higher than stalk after 8 hours storage. Titratable acidity was opposite tendency to the pH, pH was gradually decreased than initial stage during pretreatment: of leaf mustard Dolsan at 30, 40 and 50℃. After 16 hours pretreatment, the higher pretreatment temperature was, the higher pH was, but after pretreatment for 48 hours, pH of sample pretreated at 50℃ was lower than that of sample pretreated at 40℃. Antimicrobial activity of leaf mustard Dolsan extract pretreated at 30℃ was the strongest of the samples pretreated at 30, 40 and 50℃, and that of stalk part was stronger than that of leaf part. L and b value in colors was gradually decreased, and a value was increased with the passage of pretreatment time. L and b value was higher in the order of samples pretreated at 40, 50 and 30℃, and the lower pretreatment temperature was, the higher a value was. L value of stalk part was higher than that of leaf part, but a and b value of of leaf part was higher than that of stalk part.

Aspergillus sp. ISR 균주를 통한 콜레스테롤 합성저해제 lovastain의 생산

박상은,조미현,신동화,황승환,박천석 경희대학교식량자원개발연구소 2005 硏究論文集 Vol.24 No.-

본 연구에서 한국 토양에서 분리된 lovastatin 생산 균주인 Aspergillus sp. ISR 균주를 이용하여 여러 배지 조성 성분이 lovastatin의 생산에 미치는 영향을 관찰하였다. 탄소원으로는 lactose보다 glycerol 5%가 가장 효과적이었으며 질소원과 인산염의 경우는 기본 RPM배지 조성과 농도에서 보다 효과적인 것을 발견하지 못하였다. 복합영양원으로 rapeseed meal 보다는 대두박이 보다 효과적이어서 저렴한 배지원으로 사용이 가능할 것으로 사료된다. 최종적으로 최적화된 배지를 사용하여 52 mg·L^(-1)의 lovastatin을 생산할 수 있었고 이는 기존의 RPM 배지보다 수율이 4.5배 증가한 것이다. 좀 더 효과적인 lovastatin의 생산을 위하여 회분식 발효에 대한 연구와 분자유전학적인 연구를 통한 고생산 균주의 제조에 대한 연구가 진행중이다. Effects of various nutritional components on the production of lovastatin were investigated in the Aspergillus sp. ISR. Among various carbon (C) sources, glycerol was determined to be the most effective C source at the concentration of 5% (v/v). In case of nitrogen sources, 0.2% (w/v) KNO_(3) efficiently induced the lovastatin production in Aspergillus sp. ISR. Interestingly, the addition of soybean meal into the production medium enhanced the lovastatin production compared to the rapeseed meal. Conclusively, Aspergillus sp. ISR produced 52 mg·L^(-1) of lovastatin in the optimized medium containing 5% (v/v) glycerol, 0.2% (w/v) KNO_(3), 0.3% (w/v) KH_(2)PO_(4), and 0.3% (w/v) soybean meal, which was 4.5 times higher than the amount produced using the standard RPM (rapeseedmeal production medium).

저온 및 상온 저장한 백미의 품질 특성

박석규,박정로,박미연 순천대학교 기초과학연구소 1994 基礎科學硏究誌 Vol.5 No.-

The Quality characteristics of milled rice stored at 5℃ and room temperature for 6 months were investigated. Major fatty acids of milled rice were linoleic > oleic > palmitic acid. The rice stored at room temperature had slightly lower content of unsaturated fatty acids than that that stored at 5℃. The major volatile compound of the rice was hexanal, and storage temperature did not effect the content of hexanal. The content of volatile compounds of cooked rice differed greatly from uncooked rice ; in boiled rice, hexanal tended to decrease and several unidentified compounds (UN 3, 5, 7) to increase. The starch powder of milled rice stored at room temperature had higher water binding capacity, but had slightly lower iodine value, amylose content, transmittance at 625㎚, swelling power and solubility than that stored at 5℃.