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      • 근대 실내 공간 구성원리의 한국적 변형에 관한 연구 : 김수근과 김중업 작품의 실내공간 분석을 중심으로

        김은홍;남경숙 한양대학교 2007 韓國 生活 科學 硏究 Vol.27 No.1

        Modernism Architecture in international style has made new spatial paradigm using steel and glass until 1900s. This paradigm influenced in indoor space was shown to Works of four great masters, Mies van der rohe, Le Corbusier, Aalvar alto, Frank L. Wright, and some characteristics are found in four great masters' works in common. These characteristics are simplicity of spatial form, usefulness and functionality of design, openness of indoor space, Total design, internal and external interpenetration. These are shown in interior space of Korea modern architecture as changing their conditions. This study drives at what major characteristics changes the way of proper transformation and adaption in two modern architect of Korea, Kim Swoogeun and Kim Chungup as according to modern architecture principals. Some controlling principles are found out in their works, and the ways of transformation and adaption are analogy with its special occasion of Korea.

      • KCI등재

        일렬 자가조혈모세포이식을 받은 다발성 골수종 환자에서 발생한 뇌 톡소포자충증 1례

        김계형,송경호,전재현,박완범,박상원,김홍빈,김남중,김인호,오명돈 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

        Toxoplasmosis is a rare but fatal complication in hematopoietic stem cell transplant recipients, usually associated with allogeneic hematopoietic stem cell transplantation (HSCT). We report a case of cerebral toxoplasmosis in a patient with multiple myeloma, following tandem autologous stem cell transplantation. A 55-year-old Korean male presented with weakness in both legs that had progressed to both arms. A magnetic resonance imaging scan of the brain revealed multiple, variablesized ring-enhancing lesions with surrounding edema in the cerebral hemispheres and brain stem. Stereotactic biopsy revealed bradyzoites of Toxoplasma gondii in the brain tissue. The patient received trimethoprim-sulfamethoxazole, followed by pyrimethamine and sulfadiazine, accompanying treatment for progressive multiple myeloma. Cerebral toxoplasmosis should be considered as one of the differential diagnoses in patients with neurologic signs following autologous HSCT.

      • 산후에 발병한 특발성 부갑상선 기능저하증 I 예

        김정인,김상용,신병철,김경남,서영욱,이범주,김진화,배학연 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

        Hypoparathyroidism is usually the result of an inadvertent surgical removal of all the parathyroid glands, In some instances, not all the tissues are removed, but the remainder undergoes vascular supply compromise secondary to the fibrotic changes in the neck after surgery, Previously, the surgery for hyperthyroidism was the most frequent cause of acquired hypoparathyroidism. Idiopathic hypoparathyroidism is a relatively rare disease that is characterized by hypocalcemia and hyperphosphatemia due to a parathyroid hormone deficiency of an unknown cause, It usually develops at a young age, and shows various clinical symptoms and signs accompanied with hypocalcemia. In addition, it is rarely associated with polyglandular autoimmune syndrome during the follow-up. Hypocalcemia and idiopathic hypoparathyroidism associated with labor and lactation are rarely reported condition previously. We here describe a case of a woman in whom the symptomatic severe hypocalcemia appeared after her delivery. We reviewed all the previously reported cases and suggest a possible physiological explanation for the association between pregnancy, lactation, and the appearance of symptomatic hypocalcemia.

      • 지점부 다이아프램의 응력분배 거동

        김동표,정경섭,김경남,양경환 충북대학교 건설기술연구소 2002 建設技術論文集 Vol.21 No.1

        These days, bridges have a tendency to be long-spanned and simple ‘ thus, the importance of economy and efficiency has increased for bridge construction. As a result, one of the main members on which interest is focused is the diaphragms. In this study, stress variation of the support diaphragms in a steel box girder was considered. This paper deals with the behavior of the stress distribution on the diaphragms on the bearings of a closed section steel box girder bridge due to the continuous casting of concrete slab. Both experimental and structural analyses were performed to verify the behavior of the stress distribution a composite steel box girder bridge under construction. Strain was continuously checked at intervals of 10 to 30 min. from the beginning of the placement by the Time Interval Function of the measuring instrument. The variation of strain on the diaphragms on the bearings are presented herein.

      • KCI등재

        치아 수복용 불소함유 glass filler의 제조 및 특성

        김대성,최세영,김경남,김광만,김중곤 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.3

        The purpose of this study was the reaching test of restorative glass according to composition. Mixtures of SrF₂, CaF₂and SiO₂were fused in platinum crucible. The glasses were ground and fraction which passed through a 400 mesh (38㎛) sieve were collected. The powder specimens were analyzed by a DTA and XRD. Then powder specimen were inserted to D. I. water with various of dissolution time and composition at 37℃. Fluoride ion, cation release, solubility, and pH change were estimated. It was clear that the glasses were formed except S0.65. In S0.40, Tg, Ts, and Tc were 630, 672, and 813℃ respectively. In initial 0.5 hrs., amounts of released fluoride ion and cation were about 90% of total released amounts and released rate was decreased with dissolution time. Amount of released fluoride ion and cation were increased with decreasing SiO₂ in glass filler. And released rate was decreased rapidly by adding CaF₂. This was caused by structural variation in glass filler. Solubility was similar tendency with ion released. The pH of D.I. water was 4.5. But in intial 0.5 hrs., pH was 8.2∼9.8., and decreased according to dissolution time. This is caused by ionic changing with cation and H* ion.

      • KCI등재후보

        반복적인 부비동염으로 내원한 Good 증후군 1예

        송경호,김계형,김충종,박경운,전상훈,김홍빈,김남중,오명돈,최강원 대한감염학회 2007 감염과 화학요법 Vol.39 No.5

        Good 증후군은 흉선종과 면역결핍이 동반되는 질환으로, B세포의 감소로 인한 범저감마글로불린혈증과 CD4^(+)T세포의 감소로 인한 세포성 면역저하가 동시에 나타나는 것을 특징으로 한다. 본 증례는 18개월 전부터 발생한 반복적인 부비동염을 주소로 내원한 43세 남자 환자로, 내원 1년 전 흉선종절제수술을 시행받았으며, 면역학적 검사상 범저감마글로불린혈증과 T세포의 감소 등의 이상 소견이 발견되었다. 정주 면역글로불린과 경험적 항생제(amoxicillin/clavulanic acid) 사용 후 부비동염이 호전되었으며, 예방접종과 정기적인 면역글로불린 투여 후 특이 합병증없이 경과 관찰 중이다. Good's syndrome is the association of thymoma with immunodeficiency, characterized by hypogammaglobulinemia, B-cell lymphopenia and variably defects in cellular immunity with CD4^(+) T-cell lymphopenia and an inverted CD4^(+):CD8^(+) T-cell ratio. We report a 43-year-old male patient who presented with a 18-month history of productive cough and postnasal drip. One year ago, he underwent the operation for resection of a thymoma. Despite of appropriate management, sinusitis relapsed multiple times. He was found to have hypogammaglobulinemia with nearly absent B cells(4/μL). The CD4^(+) T-cell count was 554/μL with an inverted CD4^(+):CD8^(+) T-cell ratio of 0.6. His symptoms and signs improved with antibiotic treatment and monthly administration of intravenous immunoglobulin (IVIG, 400 mg/kg).

      • KCI등재SCOPUS
      • KCI등재후보

        Quartz 자극에 의한 iNOS 발현의 자가조절

        김경아,남혜윤,문제혁,정진숙,임영,정치경 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

        목적 : Rat2 섬유모세포에서 α-quartz에 의해 유도된 NOS의 조절기전을 알아보기 위하여 본 연구가시도 되었다. 방법 : Rat2 세포에 있어서 α-quartz 자극에 의한 NO와 H₂O₂의 분비 및 iNOS의 발현을 관찰하였고, iNOS 억제제인 L-NIL과 H₂O₂ 억제제인Catalase를 전처리하고 마찬가지로 NO와 H₂O₂분비 그리고 iNOS의 단백발현 정도를 western blot-ting을 이용하여 관찰하였다. 결과 : o-quartz는 Rat2 세포에서 iNOS에 의한NO와 H₂O₂의 분비를 유도하였다. L-NIL은 R3t2세포에서 D-quartz에 의한 H₂O₂의 분비와 iNOS발현을 완전히 억제하였다. Catalase로 전처리 하였을 때 o-quartz로 유도된 iNOS에 의하여 생산증가된 H2Oa가 iNOS를 억제하는 autoinhibitorypathway가 차단되어 결과적으로 H₂O₂의 분비와 iNOS의 발현이 증가하였다. 결론 : Rat2 세포에서 α-quartz에 의하여 유도된iNOS는 H₂O₂의 분비를 촉진하고 이 H₂O₂는 iNOS기능을 조절하는 자가조절기전에 중요한 역할을 하는 것으로 생각된다. Objectives : This study was performed in order to investigate the molecular mechanism regulating nitric oxide synthase (NOS) induced by α-quartz in Rat2 fibroblast. Methods : α-quartz-induced nitric Oxide (NO) anti H₂O₂ formation anti α-quarts-induced iNOS protein expression in Rat2 fibroblast were monitored. With iNOS inhibitor (L-N6- (1-iminoethyl) lysine hydrochloride, L-NIL) or antioxidant (catalase), we observed NO and H₂O₂ formation and iNOS protein expression in Rat2 fibroblast stimulated with α-quartz. Results : α-quartz stimulated iNOS-induced NO and H₂O₂ formation in Rat2 fibroblast. L-NIL inhibited H₂O₂ formation and iNOS protein expression by α-quartz in Rat2 fibroblast. Pretreatment with catalase blocked the autoinhibitory pathway of iNOS by iNOS-induced H₂O₂ therefore H₂O₂ and NO production and iNOS protein expression were increased in Rat2 fibrobalst stimulated with α-quartz Conclusion : α-quartz-induced iNOS Stimulated H₂O₂ formation in Rat2 fibroblast. INOS-induced H₂O₂ by α-quartz plays an important role in the autoinhibition pathway for regulating the iNOS function in Rat2 fibroblast

      • 가변블록을 이용한 역전파 신경회로망의 영상압축(Ⅰ)

        김경민,최남섭 麗水水産大學校産業技術硏究所 1998 産業基術硏究所 論文集 Vol.7 No.-

        We present an image compression technique using a neural network with backpropagation algorithm. The neural network has three layers : one input layer, one hidden layer and one out put layer. The inputs of the neural network are original image data, while the outputs are reconstructed image data which are close to inputs. If the amount of data required to store the hidden unit values and the connection weights to the output layer of the neural network is less than the original data, compression is achieved. In this paper, we proposed the variable block size method considering image complexity. This method determines a block size for the image by PSNR test. In comparison with conventional constant block size method, this method improves compression ratio with a little loss of PSNR.

      • KCI등재

        레이저를 이용한 치과용 도재의 glazing 효과

        김광만,김경남 대한치과기재학회 1996 대한치과재료학회지 Vol.23 No.2

        Two types of dental ceramics for metal-ceramic system(CeramcoⅡ, VMK 68) and one type of dental ceramic for all-ceramic system(Empress) were choosed and all were A2 shade. Specimens were made by manufacturer's instruction and divided by 3 experimental groups that mechanical polished using Sofu porcelain kit(Polish), furnace glazed using porcelain furnace(Glaze) and laser glazed using CO₂laser(Laser). Controls were roughened by #100 sandpaper. The color changes were measured L*, a*, b*, according to CIELab system by spectrophotometer (Minolta 3500D, Japan) and surface roughness were measured Ra and Rz by surface troughness tester(Surfrecord, Kosaka, Japan). The results were as follows: 1. Only all-ceramic systems (Empress)were glazed by laser but metal-ceramics systems (Ceramco Ⅱ and VMK 68) were cracked by laser. 2. All experimental groups had lower L* value and higher b* value but had no significant difference in a* value compared with control(p<0.05). 3. All-ceramic systems(Empress)had highest L* value and b* value but lowest a* value compared with other systems in all treatment groups(p<0.05). 4. The surface roughness of control were highest in all treatment groups and Empress were lowest in all products(P<0.05). Dental all-ceramic systems had a possibility to laser glazing and L* values were decreased and b* values were increased in polishing, glazing and laser glazing group.

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