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정성주,김성범,박대원,정혜원,기세윤,권정아,박만석,박미연,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3
브루셀라증은 전 세계적으로 발생하는 인수공통 전염병중에 하나로서, 본 증례는 국내에서 감염된 가축에 대한 노출력이 없는 집단에서 현증 브루셀라증이 발생한 첫 증례이기에 문헌 고찰과 함께 보고한다. 또한 환자가 근무하였던 축산물 부산물 시장에서 역학 조사를 실시하여, 현증환자 및 기감염자를 발견하여 축산물 부산물 시장 근무자에서 현증 브루셀라증이 발생할 위험성을 평가하였다. 역학 조사 결과 축산물 부산물을 다루는 일을 하는 사람들에서 감염된 가축과의 직접 접촉이 없이도 브루셀라증이 발생할 수 있음을 알 수 있었다. Brucellosis is a world-wide zoonotic disease. We report the first case of brucellosis in South Korea that is not related to direct contract with intected cattles. The patient had been working in the market of by-product, stock raising for twenty years and complained of 1-month history of fever, chill, and intermittent epistaxis. We confirmed brucellosis by anti-brucella antibody test and PCR. After 6 weeks' treatment with rifampicin and doxycycline, fever and chilling subsided, and, generalized weakness and oral intake improved. We performed seroepidemiology study against workers who were working in the same market as the patient. However, we couldn't find out other cases with seropositivity. We concluded that although the workers of by-product market have a risk of getting brucellosis, the risk is low.
홍석주(Suck-Joo Hong),박영배(Young-Bae Park) 한국정보과학회 1998 한국정보과학회 학술발표논문집 Vol.25 No.1B
최근에 빌딩 근무자의 사무능률을 향상시키고 쾌적한 근무환경을 조성하며 관리유지비를 절감하는 등 과학적이며 기능적인 인텔리전트 빌딩을 구축하기 위한 통합 데이터베이스 시스템의 필요성이 증대되고 있다. 본 논문에서는 빌딩내의 공조설비, 전력설비, 조명설비, 사무환경, 주차관제, 기기가동현황, 시설물품, 에너지 사용현황 등 각종 설비 상호간을 종합적으로 운영하기 위한 통합 데이터베이스를 설계하고 구현하였다.
Life-Threatening Simultaneous Bilateral Spontaneous Tension Pneumothorax − A case report −
Taegeun Rim,Joo Suck Bae,Yong Soo Yuk 대한흉부외과학회 2011 Journal of Chest Surgery (J Chest Surg) Vol.44 No.3
Spontaneous pneumothorax is a common clinical problem in emergency care. However, the overall incidences of primary spontaneous pneumothorax has been reported from as low as 1.4% to 7.6%. The clinical findings of simultaneous bilateral spontaneous pneumothorax can be variable. Clinical presentation is variable, ranging from mild dyspnea to tension pneumothorax. Bilateral tension pneumothorax can defined as cases where no tracheal deviation is detected in chest X-ray, and symptoms may be equal bilaterally. Herein, we present a case with simultaneous bilateral tension pneumothorax, severely deteriorated (i.e. with loss of consciousness, cyanosis, and hemodynamically unstable), that was successfully treated with immediate large-size needle decompression.
배주환(Ju-hwan Bae),김규석(Gyu-suck Kim),조현석(Hyun-suck Joo),류제청(Je-chung Ryu),이명준(Myoung-jun Lee),문인혁(Inhyuk Moon) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.7
This paper proposes a kinematic analysis for a multi-posture controllable wheelchair. The available functions of the wheelchair are reclining, tilting, standing-up, and elevation, which are performed by controlling four linear actuators. The standing-up function is controlled by extending the back-rest and the leg-rest of the seat at once. To optimize the wheelchair posture into the human body structure, the speed of the linear actuators is controlled independently. Simulation results using a wheelchair-seat model proposed in this study show the wheelchair controllable multi-postures is feasible.
용철순,이경희,최진석,박병주,정세현,김용일,박상만,배명수,김귀자,김영식,유창훈,강성룡,유봉규,이종달,최한곤 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.1
To develop and aceclofenac soft capsule, four preparations with various solubilizers were prepared and their dissolution test was carried out. Among four preparations tested, a preparation with ethanolamine was selected a formula of aceclofenac soft capsule (Clanza S^(™), since it showed the fastest dissolution rate. Bioequivalence of aceclofenac tablet, Airtal^(™)(Dae-Woong Pharmaceutical Co., Ltd.) and aceclofenac soft capsule, Clanza S^(™)(Korea United Pharmaceutical Co., Ltd.) was evaluated according to the guideline of KFDA. Fourteen normal male volunteers (age 20-25 years old) were divided into two groups and a randomized 2×2 cross-over study was employed. After oral administration of one tablet or capsule containing 100 ㎎ of aceclofenac, blood ws taken at predetermined time intervals and the concentration of aceclofenac in plasma wa determined with an HPLC method under UV detector. The pharmacokinetic parameters (C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameters using logarithmically transformed AUC_(t), C_(max) and T_(max) between Airtal tablet and Clanza soft capsule were 2.89%, 0.18% and 43.0%, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.250(e.g.log(0.81) - log(1.23) and log(0.89) - log(1.14)) for AUC_(t) and C_(max), respectively. Thus, the criteria of the KDFA guidelines for the equivalence was satisfied, indicating that Clanza S^(™) soft capsule is bioequivalent to Airtal^(™) tablet.
성화창(Hwa Chang Sung),박진배(Jin Bae Park),정현석(Hyun Suck Jeong),주영훈(Young Hoon Joo) 한국지능시스템학회 2010 한국지능시스템학회 학술발표 논문집 Vol.20 No.2
본 논문에서는 불확실성이 포함된 비선형 스위칭 시스템의 안정화 방안에 대해 다루고자 한다. 전력 시스템을 위시로 한 많은 플랜트는 시스템상의 비선형성과 불확실성을 내포하고 있으며, 이는 실 운전에 있어서 많은 제약을 가지게 된다. 이와 같은 문제점을 극복하기 위하여 본 논문에서는 1) Takagi-Sugeno (T-S) 퍼지 모델; 2) 완화된 안정도 해석; 3) 디지털 기반 제어기 사용; 제시된 세 가지 제어 기법의 활용을 통해 문제의 해결책을 마련하게 된다. 전체 스위칭 시스템은 퍼지 제어기 설계를 통해 안정도 증명을 시도하게 되며, 디지털 재설계를 통해 시스템을 디지털화 방안을 마련하게 된다.