자궁난소질환에 대한 봉독(Bee Venom)을 활용한 국내외 연구 동향 분석

이진욱,강나훈,유은실,박남춘,양혜린,김남훈,박경선,이진무,이창훈,장준복,황덕상,Lee, Jin-Wook,Kang, Na-Hoon,Yoo, Eun-Sil,Park, Nam-Chun,Yang, He-Rynn,Kim, Nam-Hoon,Park, Kyoung-Sun,Lee, Jin-Moo,Lee, Chang-Hoon,Jang, Jun-Bok,Hwang, Deok- 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.4

Objectives: Bee Venom has been used to relieve pain and to treat various diseases, such as arthritis, cancer and skin disease. Although Bee Venom has used extensively in gynecological fields, we don't have enough evidence with it. This study is to investigate efficacy and safety of Bee Venom on women by investigating papers, then we are going to suggest the direction of research. Methods: We searched for papers which had Bee Venom from Pubmed, OASIS, Journal of Korean Obstetrics & Gynecology, Journal of Korean Medicine up to August 2017, then classified according to the type of studies. Results: Eleven papers have been finally selected. One paper was a case report about atypical squamous cells of undetermined significance. Four papers were in vivo studies about 1 endometriosis and 1 polycystic ovarian syndrome and 2 human cervical cancer. Among eight papers that were in vitro studies, four papers were reported about ovarian cancer and four papers reported about human cervical cancer. Among ten papers that were experimental studies, two papers have been studied both in vivo and in vitro. Most of studies have shown that Bee Venom is useful for gynecological disorders. Conclusions: It has been identified that Bee Venom could be a good treatment for female disorder. However, more clinical reports and well-designed studies will be needed.

광경화 3D 프린팅 공정을 위한 실리카 복합소재 합성 및 특성 분석

이진욱,남산,황광택,김진호,김응수,한규성,Lee, Jin-Wook,Nahm, Sahn,Hwang, Kwang-Taek,Kim, Jin-Ho,Kim, Ung-Soo,Han, Kyu-Sung 한국재료학회 2019 한국재료학회지 Vol.29 No.1

Three-dimensional(3D) printing is a process for producing complex-shaped 3D objects by repeatedly stacking thin layers according to digital information designed in 3D structures. 3D printing can be classified based on the method and material of additive manufacturing process. Among the various 3D printing methods, digital light processing is an additive manufacturing technique which can fabricate complex 3D structures with high accuracy. Recently, there have been many efforts to use ceramic material for an additive manufacturing process. Generally, ceramic material shows low processability due to its high hardness and strength. The introduction of additive manufacturing techniques into the fabrication of ceramics will improve the low processability and enable the fabrication of complex shapes and parts. In this study, we synthesize silica composite material that can be applied to digital light processing. The rheological and photopolymeric properties of the synthesized silica composite are investigated in detail. 3D objects are also successfully produced using the silica composite and digital light processing.

Alloy Hydride 법을 이용한 GaxIn1-xAs 증착 공정의 열역학적 해석

이진욱,박진호 ( Jin Wook Lee,Chin Ho Park ) 한국화학공학회 1996 화학공학의이론과응용 Vol.2 No.1

肛腸療法에 의한 枳實의 卽刻型 알레르기 反應 抑制 效果

이진욱,문구,원진희,Lee, Jin-wook,Moon, goo,Won, Jin-hee 대한한방안이비인후피부과학회 2000 한방안이비인후피부과학회지 Vol.13 No.1

Anal therapy is another way of taking medicine It is a traditional pathway but not available in common situation. Nevertheless. It has many benefit and usefulness, it has not treated so much. The dried immature fruit of Poncirus trifoliata L(Ji-Sil) is widely used to treat urticaria, itch and indigestion in traditional Korean Medicine. So this study was carried out to examine the effect of an aqueous extract from immature fruit of Poncirus trifoliate L. on immediate-type allergic reaction by anal administration. Anal administration of Poncirus trifoliata L. showed a marked inhibition rate in systemic immediate-type allergic reaction with a dose of 0.1 - 1 g/kg 1 hr before intraperitoneal injection of compound 48/80. Anal administration of Poncirus tnjoliata L. (0.1 -1 g/kg) significant1y reduced plasma histamine contents induced by compound 48/80. Anal administration of Poncirus trifoliata L. (10 g/kg) also inhibited to $44.6\%$ (P<0.01) local allergic reaction activated by anti-dinitrophenyl (DNP) IgE. In addition, Syzygium aromaticum dose-dependently inhibited the histamine release from the peritoneal mast cells by compound 48/80 or anti-DNP IgE. These results provide evidence that anal therapy of Poncirus trifoliata L. may be beneficial in the treatment of systemic and local immediate-type hypersensitivity by inhibition of histamine release from mast cells in vivo and in vitro.

아토피양 접촉피부염 유발 NC/Nga mouse에서 도고 온천수에 첨가한 게르마늄 성분의 효과

이진욱,고가연,정찬호,유선종,김윤희,안택원,Lee, Jin-Wook,Go, Ga-Yeon,Jung, Chan-Ho,You, Sun-Jong,Kim, Yun-Hee,Ahn, Taek-Won 대한한방안이비인후피부과학회 2014 한방안이비인후피부과학회지 Vol.27 No.4

Objectives : The purpose of this study is to investigate the effects of DOGO phreatic water containing germanium on Atopic Dermatitis in NC/Nga mouse. Methods : We made DOGO phreatic water added germanium. After making atopic dermatitis caused by sensitizing NC/Nga mouse to DNCB(dinitrochlorobenzene), we made mouse swim in tanks each filled with distilled water, tap water, DOGO phreatic water, DOGO phreatic water(added germanium) for 30minutes everyday. 3weeks later, we analyzed skin clinical score, total IgE levels(by ELISA), WBC differential counting(Neutrophils, Monocytes), absolute cell number of $Neutrophil^+Gr-1^+$, CCR3 mRNA expressions(by Real-time PCR), IL-4, IFN-${\gamma}$ production levels(by ELISA), histologic test(by H&E staining, toluidine blue staining). Results : The results of making NC/Nga mouse induced atopic dermatitis swim in tanks filled with DOGO phreatic water(contain germanium) are as follows. 1. Skin clinical scores were decreased significantly in comparison to control group. 2. Total IgG levels were decreased significantly in comparison to control group. 3. WBC differential counting(Neutrophils, Monocytes) were decreased significantly in comparison to control group. 4. Absolute cell number of $Neutrophil^+Gr-1^+$ were decreased significantly in comparison to control group. 5. CCR3 mRNA expressions were decreased significantly in comparison to control group. 6. IL-4, IFN-${\gamma}$ production levels were decreased significantly in comparison to control group. 7. The epithelial tissue thickness, leucocytes infiltration, erythema, edema, excoriation, scaling, mast cells infiltrations in dorsal skin were decreased in comparison to control group. Conclusions : These results indicate that DOGO phreatic water(contain germanium) can be used for helping treat atopic dermatitis.

절리암반에서의 근접사면굴착에 의한 기존터널 거동에 대한 실험적 연구

이진욱,이상덕,Lee, Jin-Wook,Lee, Sang-Duk 한국터널지하공간학회 2009 한국터널지하공간학회논문집 Vol.11 No.1

절리암반에시 기존 터널에 근접하여 사면굴착시 터널의 거동은 절기와 굴착사면상태의 영향을 받는다. 본 논문에서는 기존터널에 근접하여 지반을 굴착시, 절리각도와 굴착사면 경사의 영향을 파악하기 위하여 2축 실대형 모형시험장치(3.1 m*3.1 m*0.50 m(폭*높이*길이))를 이용한 시험을 수행하였다. 절리암반은 콘크리트 블록을 사용하여 모사하였으며 터널은 1/10축척(직경 0.6 m)으로 제작하였다. 절리각도는 $0^{\circ}$부터 $90^{\circ}$까지 변경이 가능하며, 굴착사면 경사는 $30^{\circ}$에서부처 $90^{\circ}$까지 가능하도록 되어 있다. 실대형 시험을 통하여 절리각도와 사면경사에 따른 터널거동과 수평지중변위를 계측, 분석하였다. 분석결과 절기각도와 사면경사가 크면 클수록, 터널 내공변위와 터널 라이닝 모멘트가 커지는 경향이 있었으며 수평지중변위 또한 절리각도와 사면경사에 많은 영향을 받고 있어 향후 사면보강에 있어 효율적 방안제시를 위한 기초자료로 활용이 가능할 것이다. When a rock slope is excavated adjacent to a existing tunnel, the behavior of the existing tunnel in the jointed rock masses is greatly influenced by the joint conditions and slope status. In this study, the effects of joint dip and slope angle close to a tunnel are investigated through a large scale model using a biaxial test equipment ($3.1\;m\;{\times}\;3.1\;m\;{\times}\;0.50\;m$ (width $\times$ height $\times$ length)). The jointed rock masses were built by concrete blocks. The diameter of the modeled tunnel is 0.6 m and the dip angles of joint vary in the range of $0-90^{\circ}$. In addition, the excavated slope angle varies within $30{\sim}90^{\circ}$. Deformational behaviors of the tunnel were analyzed in consideration of joint dip and slope angle. With increase of the joint dip and slope angle, the magnitude of tunnel distortion and the moment of tunnel lining were increased. Rock mass displacement in horizontal was also dependent on the joint dip and the excavated slope angle, which indicated the optimal slope reinforcement for a specific rock mass conditions.

CG 시뮬레이션을 이용한 단독주택지 도시설계지침별 공간구성의 선호도 평가에 관한 연구

이진욱,Lee, Jin-Wook 한국주거학회 2008 한국주거학회 논문집 Vol.19 No.4

The purpose of this study is to evaluate preferences for spatial composition by urban design guidelines of detached housing areas using CG simulation, with the aim of contributing to the improvement and management of residential townscapes. The list of urban design guidelines for detached housing areas was derived from an analysis of urban design guidelines and landscape regulations from the U.S.A, Japan, and Korea. These guidelines comprise building guidelines, landscape guidelines, street guidelines, and sign guidelines. Through the preferences revealed by CG simulation, an optimum presentation method for the urban design guidelines was determined. Based on the results of preferences, an appropriate management system and regulation standards were proposed. In conclusion, the efforts carried out on the study and legislation of a management system and regulation standards for the urban design guideline will accomplish the amenity of residential environments.

커먼레일 직접분사(CRDi)용 고압 디젤인젝터의 구동방식별 Pilot Spray 특성비교 (I) - 실제 직접분사식 디젤엔진에서의 사전분사 특성 분석 -

이진욱,Lee, Jin-Wook 한국액체미립화학회 2010 한국액체미립화학회지 Vol.15 No.1

The capability of pilot injection with small fuel quantity at all engine operating conditions is one of the main feature of the common rail direct injection system. The purpose of the pilot injection is to lower the engine noise and to reduce the NOx emissions. This study describes the pilot spray structure characteristics of the common-rail diesel injectors with different electric driving characteristics, including solenoid-driven and piezo-driven type. Namely three common-rail injectors with different electric current wave were investigated in this study. The pilot spray characteristics such as spray speed, spray tip penetration, and spray angle were obtained by spray images, which is measured by the back diffusion light illumination method with optical system for high-speed temporal photography. As this research results, it was found that pilot injection of common-rail system was effected by rate of injection with different electrical characteristic for driving the injector.

페로브스카이트 태양전지

이진욱,박남규,Lee, Jin-Wook,Park, Nam-Gyu 한국진공학회 2014 진공 이야기 Vol.1 No.4

Since the development of 9.7% efficient long-term stable solid state perovskite solar cell in 2012, intensive study on perovskite solar cell has been performed. As a result, power conversion efficiency (PCE) has reached 20.1%. In-dept study on perovskite light absorber enabled understanding of origin of superb photovoltaic performance of perovskite solar cell. In this article, historical evolutions of perovskite solar cell along with key physical properties enabling high PCE are presented. Several important results for development of high efficiency perovskite solar cell are introduced. Finally, in-present research issues and future direction for solving these issues are discussed.

PACS 환경의 DR Modality 사용에 따른 효용성 분석 - C대학병원를 중심으로 -

이진욱,홍성수,김경철,Lee Jin Wook,Hong Sung Soo,Kim Kyung Chul 대한방사선사협회 2004 대한방사선사협회지 Vol.30 No.1

According to technical development of DR modality, DR mortality is being produced by a lot of medical equipment companies ant established quirky in the hospital. Many hospitals which established the existing PACS is planning replacement of modality accord