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      • CFA Analysis에 의한 구강세균의 동정

        정현자,조명숙,지원대 한국위생과학회 2002 한국위생과학회지 Vol.8 No.2

        충치환자의 병변으로부터 세균을 분리하여 동정하였다. 10종의 세균 CHJ-1, CHJ-2, CHJ-3, CHJ-4, CHJ-6, CHJ-7, CHJ-8, CHJ-9, CHJ-10, CHJ-12이 순수분리되었고, 미국 Analytical Services, Inc.의 Cellular fatty acid analysis에 의한 identification system으로 동정한 결과, CHJ-1, CHJ-2, CHJ-3과 CHJ-12는 각각 Bradyrhizobium japonicum, Arthrobacter pascens, Staphylococcus epidermidis 및 Arthrobacter pascens와 유의성이 0.5이상으로 나타났다. Oral bacteria were isolated and identified. Ten Kinds of bacteria, such as CHJ-1, CHJ-2, CHJ-3, CHJ-4, CHJ-6, CHJ-7, CHJ-8, CHJ-9, CHJ-10, CHJ-12, were isolated from oral cavity of dental patients. These bacteria were identified by cellular fatty acid(CFA) analysis system at Analytical Services Inc. in USA. Similarity index values of bacteria, CHJ-1, CHJ-2, CHJ-3, CHJ-5, CHJ-11 and CHJ-12 were above 0.5 to Bradyrhizobium japonicum, Arthrobacter pascens, Staphylococcus epidermidis and Arthrobacter pascens, respectively.

      • 상부소환관협착에 대한 Savary-Gilliard Dilatation의 치료효과와 안전성에 관한 관찰

        정현용,육은주,임의혁,김병호,성자원,이기천,허승식,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

        For the patient with stenosis of upper digestive tract caused by either benign or malignant process, esophageal dilatation is an important therapeutic modality. We reviewed retrospectively 39 cases treated by Savary-Gilliard dilatation for upper digestive tract stenosis, and results were follows : (1) Dysphagia was improved in 95% of the patients. (2) Eight patients(20%) sufferd perforation, five of them were managed with conservative medical measures, others were managed operatively. (3) In the cases with benign stenosis dysphagia was not noticed for 8.8 months, but with malignant stenosis dysphagia was reappeared after 2.8 months despite concomitant chemoradiotherapy. In conclusion, Savary-Gilliard dilatation was an effective measure for symptome due to upper digestive tract stenosis, but more careful attention for perforation should be necessitated. Also another therapeutic modality for treatment of malignant stenosis was inevitable.

      • 위궤양에 대한 Teprenone(Selbex^�)의 임상효과

        정현용,김병호,성자원,이기천,허승식,이종선,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

        The study objective was to assess the ulcer healing effects of Teprenone, stimulator of mucus production, given in dose of 50mg tid. We reviewed 25 cases of gastric ulcer proven endoscopically and treated by Teprenone. The results were follows; 1) The healing rate of gastric ulcer was 72% after 8 weeks treatment. 2) Subjective symptoms such as epigastric pain, belching, nausea, anorexia and vomiting were subsided at 86%. 3) There were not developed any symptoms, signs and laboratory abnormality (CBC, liver funtion test, urinalysis) suggesting side effect of drugs. In conclusion, Teprenone was considered an effective and safe drug in the treatment of gastric ulcer diseases.

      • 결핵균 30 kDa 항원과 Triton X-100 Solubilized Protein 항원에 의한 대장암 주변 림프절 단핵구의 활성화

        박정규,김광호,조은경,임재현,민들레,송영자,김화중,백태현 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

        Tumor-draining lymph node mononuclear (TDLMN) cells are specifically sensitized to the growing tumor but such cells are deficient for mediating an antitumor response. In this study, we examined the feasibility of using mycobacterial 30 kDa or Triton X-100 solubilized protein (TSP) antigen to stimulate mononuclear cells of colon cancer-draining lymph node for the generation of cell mediated immune effector cells. The proliferative response of TDLMN cells stimulated with mycobacterial 30 kDa or TSP antigen was determined by ^(3)H-thymidine incorporation assay. The proliferation of TDLMN cells to mycobacterial 30 kDa or TSP antigen was significantly increased in PPD (+) patients, but a poor response to the 30 kDa or TSP antigen was observed in PPD (-). The expression on γδ T cells to mycobacterial 30 kDa or TSP antigen was assessed by flow cytometry. The γδ T cells from PPD ( + ) patient responded only to 30 kDa antigen but to TSP antigen. An investigation of cytokine mRNA expression was undertaken using reverse transcription-polymerase chain reaction (RT-PCR) to follow TDLMN cells stimulated with the 30 kDa or TSP antigens for 5 days. The IFN-γ and TNF-α mRNA expression was only induced in TDLMN cells of PPD ( + ) patient in response to the 30 kDa or TSP antigen. The IL-2 mRNA expression was induced in both PPD (+) and PPD (-) in response to the 30 kDa or TSP antigen. But the IL-4 mRNA expression was not induced in response to the 30 kDa or TSP antigen. These results suggest that the 30 kDa and TSP antigens may serve as biologic response modifier for the generation of cell mediated immune effector cells.

      • KCI등재

        뇌졸중 후 대상자의 동서재활자조관리 프로그램 개발 및 운영 효과 : A Preliminary Study

        강현숙,김원옥,김정화,왕명자,조종희 성인간호학회 2004 성인간호학회지 Vol.16 No.1

        Purpose: The purpose of this preliminary study was to develop and evaluate the effects of East-West Self-help program for Rehabilitation of post-stroke clients. Method: This program is developed through literature review, survey and seminar. The program is consisted of six sessions twice a week for 6 weeks. This program is composed of health education on stroke, exercise, oriental nursing interventions, and therapeutic recreation. The outcomes have been evaluated on the basis of perceived health status, self-efficacy. U/E function, ADLs and subjective response. Result: 1) After the 6 week program, the perceived health status had improved and the score of rehabilitation self-efficacy increased significantly. 2) After the 6 week program, the score of BADL increased significantly, but, the score of IADL was not statistically significant. 3) After the 6 week program, the amount of use and quality of movement of the affected U/E were increased significantly. 4) All of the participants showed satisfaction with this program. Conclusion: Considering these research results, the program is effective in improving functional abilities and self-management ability. Therefore this program could be continuously developed and implemented as a community based self-helf group program for post-stroke clients.

      • KCI등재

        인공 치아우식 발생 모델에서 디지털 방사선 공제술을 이용한 인접면 치아우식증의 진단

        박정훈,최용석,황의환,이기자,최삼진,박영호,김경숙,진현석,홍경원,오범석,박헌국 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.1

        Purpose : The purpose of the experiment was to evaluating the diagnostic ability of dental caries detection using digital subtraction in the artificial caries activity model. Materials and Methods : Digital radiographies of five teeth with 8 proximal surfaces were obtained by CCD sensor (Kodak RVG 6100 using a size #2). The digital radiographic images and subtraction images from artificial proximal caries were examined and interpreted. In this study, we proposed novel caries detection method which could diagnose the dental proximal caries from single digital radiographic image. Results : In artificial caries activity model, the range of lesional depth was 572-1,374 μm and the range of lesional area was 36.95-138.52mm². The lesional depth and the area were significantly increased with demineralization time (p<0.001). Furthermore, the proximal caries detection using digital subtraction radiography showed high detection rate compared to the proximal caries examination using simple digital radiograph. Conclusion : The results demonstrated that the digital subtraction radiography from single radiographic image of artificial caries was highly efficient in the detection of dental caries compared to the data from simple digital radiograph.

      • KCI등재

        아동의 창의성 신장을 위한 동화 활용 음악 학습 프로그램 개발

        유현정,김경자 이화여자대학교 사범대학 교육과학연구소 2001 교육과학연구 Vol.32 No.2

        본 연구는 초등 음악과 영역에서 아동의 창의성 신장을 위한 동화 활용 음악 학습 프로그램을 개발하고, 이를 학교 현장에서 적용할 수 있도록 하는 데 그 목적이 있다. 21세기의 세계화, 정보화, 다변화의 시대에 부응하는 초등학교 음악교육은 인간의 정서에 작용할 뿐 아니라, 아동의 창의성을 신장시킬 수 있는 음악적 경험을 제공해야 한다. 이에 친숙한 동화의 이야기 자료를 재구성하고, 그것을 음악으로 표현할 수 있는 프로그램을 개발하여 현장에서의 실제 활용에 도움을 주고자 하였다. Tyler의 교육과정 개발 모형에 기초하여 개발한 본 프로그램은 S초등학교 3학년을 대상으로 실시되었고, 프로그램을 개선하고 타당화하기 위해 창의성 검사, 음악적성 검사를 프로그램 실시 이전과 이후에 평가하였다. 프로그램의 실시 결과, 아동들의 창의성과 음악성은 통계적으로 유의미한 차이(p<.01)을 보이며 향상되었고, 아동들의 음악에 대한 전반적인 인식과 태도에 긍정적인 변화를 가져왔음이 입증되었다. 이는 본 연구에서 개발한 프로그램이 아동의 창의성을 신장시키고, 음악적 창의성의 기초가 되는 음악성과 음악적 흥미 및 정서를 풍부하게 하는데 효과적임을 보여주는 것이다. The purpose of this study was to develop a music education program which integrated the children's literature of fairy tales to enhance creativity in elementary school students. The 7th national music education curriculum emphasizes musical experiences to develop creativity in students and to enrich student's emotion. In doing so, a music education program which integrated fairy tales which most children are familiar to and interested in was developed. The program was developed following Tyler's model of curriculum development. It was implemented with 41 3rd grade students in S elementary School, Incheon for 7 weeks. The validation of the program was carried out using 'Creativity Test' & 'Musical Talent Test'. To measure students' interest and their classroom participation, teachers' participant observation and students' self-evaluation were made. And the results were compared with those of the control group. The results of the study are in the following: First, statistical differences(p<.01) between the experimental group and the control group were found in creativity and musical ability in students. It means the program developed in this study is good for the development of creativity and musical ability in students. Second, the results of teacher's participant observation and student's self-evaluation shows that students' emotion and attitudes toward music changed significantly in a positive way. These results that the music education program making use of fairy tales is effective to enhance creativity and musical ability in students and to enrich student's emotion.

      • SCOPUSKCI등재

        신장이식 환자의 근력, 근지구력, 유연성 및 일상생활활동의 변화

        안재현,하희선,홍정자 성인간호학회 2001 성인간호학회지 Vol.13 No.1

        The purpose of this study was to explore the change of muscle strength, muscle endurance, flexibility and activities of daily living to develop a rehabilitational program. The subjects were selected randomly among the patients who underwent kidney trans- plantations at one major transplantation hospital in Seoul, Korea. This study was carried out between November 23, 1999 and February 15, 2000. The subjects in this study consisted of 16 patients who had kidney transplantations between 1 month and 12 months ago prior to this study. They were all on steroids and did not take any physical exercise regularly. The muscle strength, muscle endurance, flexibility and activities of daily living were evaluated at 1st week and after 12 weeks. The data were analyzed with numbers, percentiles, mean, standard deviation and t-test. The results were as follows : 1.After 12 weeks, the grip strength was significantly decreased than 1st week(p =.0002). 2.After 12 weeks, the back lift strength was significantly decreased than 1st week(p =.0002). 3.After 12 weeks, the muscle endurance was increased than 1st week, but it was not significant(p=.5487) 4.After 12 weeks, the flexibility was significantly decreased than 1st week(p=.0002). 5.After 12 weeks, the activities of daily living was significantly decreased than 1st week(p=.0006). Like the above result, the kidney transplant receipients' muscle strength, flexibility and activities of daily living were reduced In order to solve this problem, the writer has found that program development to prevent the defects should be extremely required. Since now on the number of patients should expand. After the kidney transplantation, the periods of 4, 8, 12 and 16 weeks are extended. The writer proposes to examine the different phase of change in each periods.

      • 갑상선 유두암이 병발된 가족성 대장 용종증 1예

        백종현,소창배,이은영,이지숙,신은경,박은호,서정아,양재홍,송준영,박선자,박요한,최영식 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

        Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome, typically characterized by multiple colorectal adenomas and increased incidence of colorectal carcinomas if it is not treated. Moreover, a variety of extracolonic manifestation are seen. The prevalence of thyroid tumors developing in patients with FAP is about 1∼2%. Generally, papillary thyroid cancer indicates low mortality but ,however, as people get older, the cancer becomes more aggressive. So, the operation is required. Recently we experienced a case of FAP, presenting with papillary thyroid carcinoma, and reported with a brief review of literatures.

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