淨水場內 凝集濟 注入量 豫測을 爲한 自動制御에 關한 硏究

朱恩選,金永道 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

In our country, there are much characteristics of water quality at all seasons. Therefore the optimum coagulant dosing rate and its accurate control are is needed above all. Here, to determine the coagulant dosing rate depending on raw water quality factors, we choose the multilayer perceptron, a sort of neural network method, as a model of automatic process control in the water treatment plant system. Its application to estimate and analyze the coagulant dosing rate has been performed not only by comparative analysis with other system's actual dosing examples and statistical method but also by the improvement of conventional dosing control devices. Its usefulness has been testifed through the above methodical consideration.

가토경골에 식립한 임플란트의 골형성 양상에 관한 방사선학적 고찰

도정주,김은경 단국대학교 치의학연구소 1994 논문집 Vol.6 No.2

The success of osseointegrated dental implants seems to be associated with the enclosure of the implant in a non-pathologic connective tissue or the formation of a direct bone implant interface. The purpose of this study was to examine radiographically the bone formation of several IMZ implants in rabbit's tibia. The results were as follows : 1. Radiographic findings at 3~4 weeks after implantation showed a tendency for loss of the peri-implant radiolucency of lateral aspect. 2. Radiographic findings at 4~6 weeks after implantation showed a tendency for loss of the peri-implant radiolucency of apical aspect. 3. Radiographic findings at 3 weeks after implantation showed an evident tendency for bone apposition along the cervical portion of the implant and complete bony union can be seen at 12 weeks.

위암수술 환자에서의 cp 개발과 cp적용에 따른 질 향상 활동에 관한 연구

임은주,황순휘,박도중,하광일,배현주,김형호 한국의료QA학회 2006 한국의료질향상학회지 Vol.13 No.2

Background : In an era of increasing medical costs, safe reduction in postoperative stay has become a major focus to optimize utilization of healthcare resources. The authors aimed to evaluate the clinical significance of the critical pathway(CP) for gastrectomy patients by implementing standardized postoperative management and electronic medical records. Method : From August 2006 to April 2007, critical pathways were introduced to inpatients and outpatients with gastric cancer. 60 consecutive patients undergoing distal gastrectomy were randomly divided into two groups; 30 CP group(A) and 30 non-CP group(B). Simultaneously, we also retrospectively reviewed the records of 438 patients(C:control group) who were able to be enrolled in CP program. We compared group(A) with (B), (C) in terms of hospital stay, complication rate, use of antibiotics and hospital costs. Patient satisfaction was surveyed by questionnaires. Result : There was no significant demographic difference between group(A) and (B). Of 30 patients in group(A), 5 drop-outs and 14 variances occurred. The mean postoperative hospital stays(Laparoscopy-assisted distal gastrectomy: LADG/Open distal gastrectomy: ODG) were 7.6/10.5 days for the group(A), 8.9/12.7 days for the group(B) and 12.6/14.5 days for the group(C) (p=0.02 in LADG). The total hospital cost of group(A) had a tendency to be less than that of group(B) and the amount of hospital cost per day in group(A) was significantly higher than that in group(B). The usage rates of the first generation antibiotics were 73.33%, 63.33%, and 59.2% in group(A), (B), and (C), respectively. Patients’ satisfaction had a tendency to be higher in the CP group than non-CP group. Conclusion : The mean hospital stay in LADG patients was shortened meaningfully and hospital cost per day was enlarged after introduction of clinical pathway. It is necessary to apply a number of patients to the critical pathway and to make an effort to reduce the variation and drop-out rates.

악관절의 경두개 방사선사진에서 하악과두위 평가에 관한 연구

도정주,김은경 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

Transcranial radiograph is widely used in the diagnosis of craniomandibular disorder because it can be used by the dentist with relative ease in spite of image distortion. But correct information can be obtained only when one know the image change by projection angulation. The author compared the condyle position in the 3 groups of transcranial radiographs(horizontal angulation-0°, 5°, individualized) with that in the individualized corrected lateral tomogram by objective and subjective evaluation methods. The results were as follows : 1. Among 3 transcranial groups, the condyle position in individualized group showed the highest concordance rate with that in the tomogram group in objective and subjective evaluation methods. 2. Correlation coefficient between individualized transcranial group and tomogram group in objective evaluation method was highest(P≤0.01). 3. Image clarity in individualized transcranial group was worse than that of the other two transcranial groups.

악관절의 경두개 방사선사진에서 하악과두위 평가에 관한 연구

도정주,김은경 大韓口腔顎顔面 放射線學會 1992 Imaging Science in Dentistry Vol.22 No.1

Transcranial radiograph is widely used in the diagnosis of craniomandibular disorder because it can be used by the dentist with relative ease in spite of image distortion. But correct information can be obtained only when one know the image change by projection angulation. The author compared the condyle position in the 3 groups of transcranial radiographs(horizontal angulation - 0°, 5°, individualized) with that in the individualized corrected lateral tomogram by objective and subjective evaluation methods. The results were as follows: 1. Among 3 transcranial groups, the condyle position in individualized group showed the highest concordance rate with that in the tomogram group in objective and subjective evaluation methods. 2. Correlation coefficient between individualized transcranial group and tomogram group in objective evaluation method was highest(P≤0.01). 3. Image clarity in individualized transcranial group was worse than that of the other two transcranial groups.

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

Lipomyces starkeyi KSM 22 glucanhydrolase 함유 구강세정액의 치태 억제 효과

서은주,정현주,김도만,김상혁 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.3

A novel glucanhydrolase from Lipomyces starkeyi KSM 22 has been suggested as a promising anti-plaque agent because it has been shown to have additional amylase activity and mutanase activity besides dextranase activity and to strongly bind to hydroxyapatite. Mouthrinsing with Lipomyces starkeyi KSM 22 glucanhydrolase solution was comparable to 0.12% chlorhexidine mouthwash in inhibition of plaque accumulation and gingival inflammation and local side effects were less frequent and less intense in human experimental gingivitis. In this study, Lipomyces starkeyi KSM 22 glucanhydrolase mouthrinses (1 and 2 unit/ml) were compared with a control mouthrinse (commercial 0.01% benzethonium chloride mouthrinse, Caregargle^(�), Hanmi Pharmaceuticals) in the ability to inhibit on plaque formation. A 3-replicate clinical trial using 4-day plaque regrowth model was used. Fifteen volunteers were rendered plaque-free on the 1st day of each study period, ceased toothcleansing, and rinsed 2X daily with allocated mouthrinse thereafter. On day 5, plaque accumulation was scored and the washout periods was 9 days for the next trial. Lipomyces starkeyi KSM 22 glucanhydrolase(1 unit and 2 unit)- containing mouthrinse resulted in significantly lower plaque formation in plaque area and thickness, compared to the control mouthrinse. There was no significant difference in plaque inhibition between enzyme-mouthrinses at 2 different concentrations used. This glucanhydrolase-containing mouthwash resulted in significantly lower plaque area severity index score and tended to have lower plaque thickness severity index score than those of control mouthrinse. But there was no significant difference according to the enzyme concentration. From these results, Lipomyces starkeyi KSM 22 glucanhydrolase-containing mouthrinse has greater inhibitory effect of plaque formation than commercial mouthrinse alone. Therefore, this glucanhydrolase preparation is a promising agent for new mouthwash formulation in the near future.

Isoquinolinium Chlorochromate와 Quinolinium Chlorochromate를 이용한 알코올류의 선택적 산화반응

최선도,박영조,이은주 三陟大學校 産業科學技術硏究所 2003 産業科學技術硏究論文集 Vol.8 No.2

Isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) were synthesized. which were used to oxidize benzylic alcohol, allylic alcohol. primary alcohol and secondary alcohols in DMF to give aldehyde of each compound. Their structures were verified by IR, EA and ICP. The oxidation of alcohols was examined by isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) in DMF. As a result, isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) were found as efficicent oxidizing agents that converted benzylic alcohol, allylic alcohol, primary alcohol and secondary alcohols to the corresponding aldehydes or ketones. The selective oxidation of alcohols was also examined by isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) in DMF. isoquinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) and quinolinium chlorochromate(C_(9)H_(7)NHCrO₃Cl) were selective oxidizing agents of benzylic alcohol. allylic alcohol and primary alcohol in the presence of secondary alcohols.

저칼슘식이 생쥐 하악골에서 파골세포의 Tartrate저항성 산성인산분해효소 활성에 대한 세포화학적 연구

박은주,임도선,김현만,고재승 대한구강해부학회 1994 대한구강해부학회지 Vol.18 No.1

The present study was carried out to exanine the morphological changes and TRACP (Tartrate resistant acid phosphatase) activity in the resorption of mandibular bones of mouses resulted, established by low calcium diet. Mice were divided into two groups; one was the calcein group for fluorescent microscopy, the other was the non-calcein group for light and electron microscopy. After calcein injection, mice(ICR) were fed either a low calcium diet (0.01% Ca, 0.75% P) or control diet (0.1% Ca. 0.75% P). Non-calcein group were also fed a low calcium diet or control diet. Mice were sacrificed on 3, 7 and 14 days. For fluorescent microscopy study, fixed undecalcified alveolar bones were embedded in Epon 812, and ground sectioned to study the new bone formation after calcein injection. For the TRACP histochemical study, fixed decalcified alveolar bones were incubated in p-NPP (p-nitrophenyl phosphate) media. For the transmission electron microscopic study, incubated alveolar bone were post fixed in OsO_(4), embedded with Epon 812 for the study of TRACP localzation and activity. The observed results were as follows. 1. Low calcium diet induced bone resorption in buccal and lingual sides of alveolar bone, while the lingual side of alveolar bone was not resorbed in the control group. Bone resorption increased over the period of low calcium diet. 2. The alveolar bone proper of the lingual alveolar bone continued to deposit new bone of the periodontal side even after the low calcium diet. 3. After low calcium diet TRACP activity increased in the cytoplasm of osteoclast, extracellular ruffled border. TRACP activity was also found at the eroded bone matrix after bone resorption, and in the cytoplasm of detached osteoclast. In the immature osteoclast enzyme activity was confined in rER. No enzyme activity was found in the osteoblast.

Isoquinolinium Dichromate에 의한 Alcohol류의 산화반응 속도론과 메카니즘

최선도,박영조,이은주 三陟大學校 産業科學技術硏究所 2003 産業科學技術硏究論文集 Vol.8 No.2

Isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] was synthesized by the reaction of isoquinoline with chromium(VI) trioxide in water. isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] structure was verified by IR. EA and ICP. The oxidation of benzyl alcohol by isoquinolinium dichromate[(C_(9)H_(7)NH)₂Cr₂O_(7)] in carious solvents showed that the reactivity increased with the increase of the dielectric constant s order: cyclohexen < chloroform < acetone < acetonitrile. In the presence of acid, isoquinolinium dichromate [(C_(9)H_(7)NH)₂Cr₂O_(7)] oxidized the substituted benzyl alcohols in N,N-dimethylformamide. The Hammett reaction constant p was -0.69 at 303K. The observed experimental data was used to rationalize the hydride ion transfer in the rate-determining step.