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배상남(Sang Nam Bae),정필주(Pil Ju Jeong),남상욱(Sang Ook Nam) 대한소아신경학회 2001 대한소아신경학회지 Vol.9 No.1
저자들은 29개월 된 남아에서 생후 6개월경부터 교대성으로 편마비 증상을 보였으며, 편마비 증상을 보일 때 시행한 뇌파 검사, 뇌 자기 공명 영상 촬영, 뇌 자기 공명 영상 혈관 조영술 및 뇌 단일 전자 방출 전산화 단층 촬영상 특이 소견을 보이지 않았던 소아 교대성 편마비 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Alternating hemiplegia of childhood(AHC) is a rare but clinically distinct syndrome characterized by onset before 18 months of age, frequent attacks of alternating paralysis, nystagmus transient ocular palsies, other autonomic dysfunction, and the development of cognitive impairment and a choreoathetotic movement disorder. The case is a 13 month-old boy who has presented repeated episodes of alternating hemiplegia from the age of 6 months at a frequency of several times per month, which was lasting for two or three days. The diagnosis was based on clinical features. Frequently such hemiplegic attacks were accompanied by irratability. He had mental retardation, neurodevelopmental delay, and seizure attacks. EEG, brain MRI, Brain MR angiography, and Tc-99m HMPAO-brain single photon emission compute tomography(SPECT) failed to reveal any significant abnormal finding during the hemiplegic attacks. We tried calcium-entry block and flunarizine to relieve the hemiplegic attacks, but the frequency and severity of the hemiplegic attacks were not decreased by flunarizine therapy.
배명남,배상묵,김은영,주연호,김명환 대한췌담도학회 2011 대한췌담도학회지 Vol.16 No.1
Carcinoid tumors of the ampulla of Vater is very rare. Only 109 cases have been reported in the international literatures and 17 in Korea. Unlike duodenal carcinoids, their metastasis is not related with tumor size in foreign reports. Thus, treatment is surgical resection even in small tumors. We experienced a rare case of carcinoid tumor of ampulla of Vater and report here with reviews of all domestic cases.
Mucosal Schwann-Cell Hamartoma Diagnosed by Using an Endoscopic Snare Polypectomy
배명남,이정은,배상묵,김은영,김은옥,정성훈,오정환,민기옥 대한대장항문학회 2013 Annals of Coloproctolgy Vol.29 No.3
Colorectal polyps of mesenchymal origin are a rare group of colorectal disorders. A ‘‘mucosal Schwann-cell hamartoma,”which is one type of polypoid lesion that originates from the mesenchyme, is a newly-proposed disease entity to be distinguished from the neurofibromas found in type-1 neurofibromatosis. This lesion is composed of pure Schwann-cell proliferation in the lamina propria and shows diffuse immunoreactivity for the S-100 protein. We report a case of a polypoid lesion of the colon with the features of this recently-proposed disease entity.
Recurrent Insulin Autoimmune Syndrome Caused by α-Lipoic Acid in Type 2 Diabetes
배상묵,배명남,김은영,김일규,서민우,신진경,조성래,정귀화 대한내분비학회 2013 Endocrinology and metabolism Vol.28 No.4
Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia caused by insulin autoantibodies in the absence of exogenous insulin administration. Some drugs containing sulfhydryl compounds are known to initiate the onset of IAS. A 67-year-old female who had diabetes for 5 years visited the outpatient clinic at our institution due to diabetic peripheral polyneuropathy. She was prescribed α-lipoic acid (ALA), which contains two sulfur atoms. Two weeks later, she complained of recurrent hypoglycemic symptoms. We detected a high level of insulin and high titers of insulin autoantibodies. Her human leukocyte antigen (HLA) genotype included the DRB1*0406 allele, which indicates a high level of susceptibility to IAS. She was treated with prednisolone. After this episode, she experienced two more hypoglycemic events after taking ALA for diabetic neuropathy in other hospitals. As ALA can be used to treat diabetic peripheral polyneuropathy, physician discretion is advised based on the possibility of IAS due to ALA in diabetic patients.