영유아 발달검사의 실무 Ⅱ - 베일리 검사를 중심으로 -

노주선 한국모자보건학회 2002 한국모자보건학회 학술대회 연제집 Vol.2002 No.1

코로나 블루, 어떻게 극복할 것인가?

노주선 한국지방재정공제회 2020 지방재정 Vol.2020 No.4

Alzheimer병의 진단적 평가

김도관,노주선 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

The early identification of Alzheimer's disease (AD) will enable the start of antidementia treatments before extensive brain damage develops. Knowledge of the natural history of AD in terms of progression through symptomatic domains that include mood changes, loss cognitive abilities as well as functional autonomy, and emergence of neuropsychiatric features has also helped in defining the "typical" AD patient and in selecting outcome variables relevant to stage of disease under study. The diagnosis of AD is based on numerous clinical, neuropsychological, neuroradiological, and neurophysiological evaluations, but a define diagnosis can only be established at autopsy or by brain biopsy. The next stage in the diagnosis of AD will be the identification of people in the incipient presymptomatic stages, using sensitive and specific biological measures such as high resolution imaging of brain structures, combined with relevant neuropsychological tests of memory and language. Because the need for a simple and accurate diagnostic marker is increasing as new drug treatments emerge, intensive research to identify diagnostic markers is now in progress.

셋트 제품의 컨테이너 적재 알고리즘 개발에 관한 연구

김홍배,노재정,강주선 慶星大學校 1998 論文集 Vol.19 No.1

This study is focused on the methodology for the determination of the loading pattern for set products which can be charactertized by the fact that various kinds of parts should be provided together in order to function as one product such as home appliances or military supplies. This study is composed of the development of the mathematical model and its solution algorithm. The model tries to maximize the utilization rate of the loading space under the condition that the same number of the components of each set product should be loaded. This study can give the loading pattern and present the quantity information on the sub-set products to the user. The result of this study is compared with George & Robinson's algorithm under the same condition that this study is performed.

한국어판 부모, 교사 ADHD 평가 척도의 신뢰도와 타당도 연구

소유경,노주선,김영신,고선규,고윤주 대한신경정신의학회 2002 신경정신의학 Vol.41 No.2

연구목적: ADHD 아동을 조기에 선별하여 치료적 서비스를 제공하는 것은 ADHD로 인한 이차적인 학업 및 정 서문제를 예방하기 위해서 중요하다. 본 연구에서는 한국어판 부모, 교사 ADHD 평가 척도의 신뢰도 와 타당도를 살펴보고자 한다. 방 법: 안양지역의 두 초등학교에 재학중인 1학년에서 6학년 아동들이 본 연구의 연구대상이 되었다. 아동 들의 교사 및 부모는 ADHD 평가 척도를 완성하였으며, 부모들은 추가로 K-CBCL과 Conners 척도 를 완성하였다. 통계방법으로는 기술적 통계, 상관분석 및 t 검증과 변량분석을 사용하였다. 결 과: 총 1044명의 아동들이 본 연구에 참여하였다. 부모, 교사 ADHD 평가 척도의 평정자간 신뢰도는 유 의미한 것으로 나타났으며, 연령별 내적 일치도 또한 유의미하게 높은 것으로 나타났다. ADHD 평가 척도와 K-CBCL, Conners 척도의 상관관계는 유의미한 수준으로 본 척도의 공존 타당도는 유의미 한 것으로 나타났다. 결 론: 한국어판 부모, 교사 ADHD 평가 척도는 ADHD 아동들의 문제행동을 평가하는데 유의미한 신뢰도 와 타당도를 가지고 있는 도구로 ADHD의 평가 및 진단에 유용하게 사용될 수 있을 것으로 보인다. 추 후 임상군과의 비교를 통한 연구가 필요할 것이다 Objective:It is important to identify and treat ADHD children early to prevent secondary academial and emotional problem. The Purpose of this study is to investigate the reliability and validity of Korean parent and teacher ADHD Rating Scale. Method:First to sixth graders in two elementary schools in Anyang City participated in this study. Teachers and parents completed ADHD Rating Scale. Additionally parents completed K-CBCL and Conners scale. Descriptive statistics, correlation, t-test and analysis of variance were performed. Result:A total of 1044 students participated in this study. Correlation of rater reliabilities between parent and teacher was significantly close. And Internal consistency by age was high. As correlations among ARS, K-CBCL, Conners scale were high, the ARS scores can be validated. Conclusion:Korean parent and teacher ADHD Rating Scale has high reliability and validity. This scale will be a useful tool for ADHD evaluations and diagnosis. A study of comparing clinical groups is suggested.

한국형 또래지명 설문지(K-PNI) 개발 연구 : 집단따돌림 측정 도구

김영신,고윤주,노주선 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.5

연구목적 : 집단따돌림은 학교폭력의 한 형태로서 피해 및 가해 학생들이 여러 가지 행동 및 정서장애를 가지고 있는 등 소아청소년 정신과 영역에서 관심을 가져야 하는 분야임에도 불구하고 체계적이며 조직적인 접근이 이루어지지 못하여 왔다. 본 연구에서는 집단따돌림과 또래 괴롭힘에 관한 현상을 객관적이고 효율적으로 평가할 수 있는 한국형 또래지명설문지를 개발하고 이에 대한 신뢰도와 타당도를 검증하고자 한다. 방 법 : 안양시 내 2개 초등학교 4, 5, 6학년을 대상으로 K-PNI와 또래수용도, 자아지각 설문지를 실시하였다. 통계방법은 Varimax Rotation Factor Analysis, Cronbach's Alpha Reliability Analysis, Pearson's Correlation Analysis를 사용하였다. 결 과 : 총 532명(남녀비=1 : 1, 학년비=1 : 1 : 1.2)의 학생들이 본 연구에 참여하였다. K-PNI는 집단따돌림의 피해자와 가해자를 잘 구분하고 신뢰도가 0.90∼0.94 사이로 높은 신뢰도를 가진 도구로 평가되었다. K-PNI는 가해자 군과 함께 피해 유형을 소극적인 형태의 따돌림인 소외형과 언어적폭력형을 한 군으로, 또한 좀더 적극적인 형태의 신체적 폭력형과 강압형을 다른 한 군으로 분리할 수 있었다. 또한 K-PNI와 또래수용도, 자아지각 중 신체, 인지 및 사회적 자아지각과는 유의한 상관관계를 보여 K-PNI 피해 및 가해 아동 분류가 타당함을 시사하였다. 결 론 : K-PNI는 집단따돌림 및 또래 괴롭힘의 행동을 객관적으로 구분할 수 있는 높은 신뢰도와 타당도를 가진 도구로서 앞으로의 집단따돌림 및 또래 괴롭힘의 연구에서 유용하게 사용될 수 있는 도구가 될 것이다. Objectives : School bullying is Known to be related to behavioral, emotional and social problems both in victims and perpetrators. The aims of this study are to develop a Korean-Peer Nomination Inventory(K-PNI), which can identify victims and perpetrators of school bullying in an objective and effective way, and to examine its reliability and validity. Methods : Fourth to 6^th graders of two elementary school in An Yang city completed K-PNI, Peer Acceptance Scale and Self-Perception Scale. Varimax Rotation Factor Analysis, Cronbach's Alpha Reliability Analysis and Pearson's Correlational Analysis were performed for statistical analyses. Results : Total of 532 students(male : female=1 : 1 : 4^th : 5^th : 6^th grader=1 : 1 : 1.2) par-ticipate in this study. Factor analysis showed that K-PNI identified victims and perpetrators of school bullying effectively with excellent reliability(Chrobach's alpha ; 0.90-0.94). Victims were further divided into two categories ; passive bullying including exclusion and verbal abuse, and active bullying including physical abuse and being forced. K-PNI, Peer acceptance scale and Self-perception scale were significantly correlated, reflecting its validity identifying victims and perpetrators of school bullying. Conclusion : K-PNI is an effective tool with excellent reliability and validity to identify victims and perpetrators of school bullying. K-PNI is expected to be a useful tool in future studies of school bullying and school violence.

한국어판 부모 및 교사용 ADHD 평가 척도(K-ARS)의 규준연구

김영신,소유경,노주선,최낙경,김세주,고윤주 대한신경정신의학회 2003 신경정신의학 Vol.42 No.3

Objectives:Identifying children with Attention-Deficit/Hyperactivity Disorder (ADHD) and providing early therapeutic interventions for them are important to prevent secondary problems in academic achievement and emotional disturbances. The aims of the study is to examine the characteristics of K-ARS for parents and teachers, a screening questionnaire to identify children with ADHD, by age and sex of the children, to examine its clinical validity, and to provide norm data of K-ARS for school-aged children which will facilitate the use of K-ARS in clinical practice and research. Methods:Randomly selected 1st to 6th graders of the two elementary schools (N=1044) in Anyang City participated in this study. Twenty three children diagnosed with ADHD at the child and adolescent clinic at the Hallym University Sacred Heart Hospital were included in this study for the analysis of validity. Parents and teachers completed K-ARS. Descriptive statistics, t-test and analysis of variance were performed. Results:K-ARS scores showed significant difference according to the gender, with boys having higher scores than girls. There was no significant difference of the scores by ages. Validity analysis showed that K-ARS distinguishes children with ADHD from children without ADHD well. The normative data were presented by age and sex. Conclusion:K-ARS for parents and teachers has an excellent clinical validity to discriminate children with ADHD from children without ADHD. Different normative data of K-ARS need to be used due to the gender difference. K-ARS is a useful tool for screening and identifying children with ADHD. Future studies are required to include larger samples with adolescents in various geographic areas

한국판 Mini International Neuropsychiatric Interview 타당도 연구

유상우,김영신,노주선,오강섭,김찬형,남궁기,채정호,이기철,전성일,민경준,오동재,주은정,박현주,최영희,김세주,Yoo, Sang-Woo,Kim, Young-Shin,Noh, Joo-Sun,Oh, Kang-Seob,Kim, Chan-Hyung,NamKoong, Kee,Chae, Jeong-Ho,Lee, Gi-Chul,Jeon, Seong-Ill,Min, Kyun 대한불안의학회 2006 대한불안의학회지 Vol.2 No.1

Objectives : In the psychiatry, structured interview is very important tool to be used in epidemiological or psychopharmacological studies. However, investigators often find that the administration of comprehensive diagnostic interviews is time-consuming and expensive to be used in clinical or research settings. Considering these points, Sheehan and his colleagues developed MINI (Mini International Neuropsychiatric Interview) to meet the need for a brief, reliable, and valid structured diagnostic interview for psychiatric disorders. The MINI has been translated into many languages and used in many countries. Therefore, we translated the MINI into Korean and determined its validity in this study. Methods : Twohundred seventy patients and normal subjects participated in the validation of the MINI versus an expert's professional opinion. Schizophrenia and other psychotic disorders, mood disorders including major depressive disorder and bipolar disorder, anxiety disorders including panic and other phobic disorders, and alcohol dependence were included in this study. The validity was obtained by examination whether MINI based diagnoses were compatible with diagnoses by expert psychiatrists. Results : The range of Kappa values was 0.22 (somatoform disorder) to 0.93 (bipolar disorder - past). Overall agreement between MINI and expert's diagnoses were good. The Kappa values for anxiety disorders seemed to be higher than those for other disorders. Conclusion : The MINI Korean version has the good validity. It also has potential applications as a diagnostic tool for psychiatric disorders.

초등학생에서 집단따돌림의 유병률과 이와 관련된 정신병리현상

김영신,고윤주,노주선,박민숙,손석한,서동향,김세주,최낙경,홍상의 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.5

연구목적 : 학교폭력의 가장 흔한 형태인 집단따돌림은 피해아동 및 가해아동 모두에서 다양한 행동, 정서 및 사회적 문제와 연관되어 있는 것으로 알려져 있다. 본 연구에서는 지역사회내의 초등학교 고학년 학생들을 대상으로 집단따돌림의 유병률과 집단따돌림과 관련되어 아동에게 나타나는 정신병리 현상에 대하여 조사하고자 한다. 방 법 : 안양지역의 두 초등학교에서 무선으로 선출된 두 학급의 4, 5, 6학년 학생들이 본 연구의 연구대상이었다. 학생들은 한국형 또래지명설문지(K-PNI)를 완성하였고, 교사 및 부모는 ADHD Rating Scale(ARS)과 Conners 척도를 완성하였으며 부모들은 추가로 아동행동조사표를 완성하였다. 통계방법으로는 기술적 통계, 다중회귀분석 및 다중로지스틱 회귀분석을 사용하였다. 결 과 : 총 532명의 학생들이 본 연구에 참여하였다. 집단딸돌림의 피해자, 가해자 및 피해자 겸 가해자의 유병률은 각각 48%, 45%, 30%로 나타났다. 심한 집단따돌림의 유병률은 2.1∼4.1% 사이였다. 집단따돌림의 피해아동와 피해자 겸 가해아동들은 교사와 부모에 의해 부주의하고 수동적이며 사회적으로 미성숙하고 공격성이 있는 것으로 평가되었으며 학년이 올라 갈수록 피해자가 되는 경향이 적은 것으로 나타났다. 가해 아동은 행동문제와 관련되어 있었으며 남아에게 많은 것으로 나타났다. 결 론 : 집단따돌림은 한국 초등학교 고학년 학생들 사이에서 매우 흔하게 일어나는 현상으로 보인다. 집단따돌림의 경험을 한 아동은 그렇지 않은 아동에 비해 더 많은 정신병리 현상을 보였다. 이러한 정신병리와 집단따돌림과의 인과관계를 밝히기 위해서는 집단따돌림을 경험한 아동에 대한 추적 조사가 필요할 것이다. Objective : School bullying, the most prevalent type of school violence, is Know related to various behavioral, emotional and social problems both in victims and per The purpose of the present study is to investigate the prevalence of school bullying psychopathology in a community sample of elementary school students. Method : Fourth to 6^th graders of two randomly selected classes in two elementary Anyang City participated in a cross-sectional study. Study subjects completed Nominating Inventory(K-PNI). Parents completed Korean-Child Behavior Checklist(KADHD Rating Scale(ARS) and Conners Scales for parents, and teachers completed Conners Scales for teachers. Descriptive statistics, multiple linear and logistic regress performed. Results : A Total of 532 students participated in this study. Prevalence of victims, and victim-perpetrators were 48%, 45%, and 30% respectively. Extreme victims and of school bullying ranged from 2.1∼4.1%. Inattention-passivity in teachers' Conn social immaturity or aggression in K-CBCL were positively associated with victims perpetrators, and grade was negatively related to school bullying. Conduct problem in Scale for teachers and emotional instability in K-CBCL, and male gender were positively with perpetrators. Conclusion : School bullying is very common in Korean children of elementary Those who had experienced school bullying, either as victims or as perpetrators, cantly more psychopathology than their counterparts. To clarify a causal relationship psychopathology and school bullying, a longitudinal follow-up study is suggested.

The Reliability and Validity of Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version-Korean Version (K-SADS-PL-K)

김영신,천근아,김붕년,장순아,유희정,김재원,조수철,서동향,배명옥,소유경,노주선,고윤주,Keith McBurnett,Bennett Leventhal 연세대학교의과대학 2004 Yonsei medical journal Vol.45 No.1

In order to develop a structured and objective diagnostic instrument, authors completed: (1) the translation and back translation of the Korean version of the Kiddie-Schedule for Affective Disorders and Schizophrenia - Present and Lifetime Version (K-SADS-PL) and (2) the examination of its validity and reliability of the K-SADS-PL-Korean version (K-SADS- PL) when used with Korean children. A total of 91 study subjects were recruited from child and adolescent psychiatry outpatient clinics. Clinical diagnoses were used as a gold standard for the examination of validity of K-SADS-PL-K. Consensual validity of threshold and sub-threshold diagnoses were good to excellent for attention-deficit/hyperactivity disorder (ADHD), fair for tic and oppositional defiant disorders, and poor to fair for anxiety and depressive disorders. Inter-rater and test-retest reliabilities were fair to excellent for ADHD and tic disorder. The significant correlations between the K-SADS-PL-K and Korean Child Behavior Checklist (K-CBCL) were found, which provided additional support for the concurrent validity of the K-SADS-PL-K. Sensitivities varied according to the diagnostic categories, but specificities remained high over all diagnoses, suggesting that the K-SADS-PL-K is a desirable confirmatory diagnostic tool. The results of this study suggest that the K-SADS-PL-K is an effective instrument for diagnosing major child psychiatric disorders, including ADHD, behavioral disorders and tic disorders in Korean children. Future studies will examine the validity and reliability of the K-SADS-PL-K in larger samples, including adolescents and community samples on a variety of child and adolescent psychiatric disorders.