간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

암남공원의 식물상과 삼림식생에 관한 연구

남정칠,박승범,김승환,강영조,이기철,이정아 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.1

The objective of this study is to analyze the flora and forest vegetation of Amnam urban natural Park. 10 transects of quadrat of 10×10m were selected for the experiment. They were surveyed from January to October 1997. The obtained results were summerized as follows ; 1. The flora of plants distributed in Amnam Park was 88 families, 245 genus, 374 species. Dicotyledom in an angiosperm was 81.3% of total percentage was 73 families, 194 genus, 304 species, Monocotyledonous plant was 13.9% of total percentage was 7 families, 38 genus, 52 species, Gymnospermous plant was 2.1% of total percentage was 4 families, 5 genus, 8 species. Pteridophyta was 2.4% of total percentage was 3 families. 7 genus, 9 species, Shave grass was 0.3% of total percentage was 1 family, 1 genus, 1 species. 2. The representative wood plants of Amnam Park were Pinus thunbergii, Machilus thunbergii, Camellia japonica, Quercus spp., Celtis sinensis, Morus bombysis, Prunus sangentii, Sorbus alnifolia, Albizzia julibrissin, Juniperus rigida, Platycaya strobilacea, Lespedeza spp., Zanthoxylum piperitum, Zanthoxylum schinifolium, Rhus spp., Carpinus coreana, Mallotus japonicus. Ficus erecta, Pittosporum tobira, Eurya japonica. Elaeagnus macrophylla. 3. The area of plant community in Amnam Park was 84.29% in Pinus thunbergii community. 6.7% in Quercus dentata-Celtis sinensis community, 1.5% in Pittosporum tobira-Eurya japonica community, 1.4% in Quercus aliena-Prunus sargentii community, 1.29% in Pinus thunbergii-Pittosporum tobira community, 1.27% in Pinus thunbergii-Eurya japonica community.

당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

대구시 공공디자인의 시민효능감과 만족도 분석

안성조(Ahn, Sung Jo),최영은(Choi, Young Eun),박소정(Park, So Jung),김영희(Kim, Young Hee) 대구과학대학교 국방안보연구소 2020 사회융합연구 Vol.4 No.2

본 연구는 대구시를 사례로 공공디자인의 시민효능감과 만족도를 분석하는 것이다. 이를 위해 선행연구 및 이론 고찰을 통해 광역지방자치단체 공공디자인의 의의를 살펴보았다. 이를 통해 분석모형을 설정하고 공공디자인의 시민효능감과 만족도, 시민만족도의 영향요인을 분석하였다. 분석자료는 공공디자인을 이용하는 대구시민을 대상으로 설문조사를 시행하고 빈도분석, 분산분석, 다중회귀분석을 시행하였다. 분석결과는 다음과 같다. 첫째, 공공디자인의 시민효능감에서 공공공간은 공원이 가장 높았다. 권역별로 살펴보면 칠곡, 팔공은 높은 반면 달성과 시가지는 낮았다. 둘째, 공공건축물은 공공청사가 가장 높았다. 권역별로는 칠곡, 팔공은 높았고 반면에 달성과 시가지는 낮았다. 셋째, 공공시각매체는 교통관련 시각매체가 높았다. 권역별로는 수성, 팔공이 높고 달성이 낮았다. 넷째, 공공시설물은 도로시설물이 높았다. 권역별로는 수성이 높았다. 다섯째, 옥외광고물은 건물부착형 옥외광고물이 높았고 권역은 월배와 수성이 높았다. 여섯째, 공공디자인의 시민만족도 영향요인은 공공공간, 공공시설물, 공공건축물 등의 순으로 나타났다. This study aims at analyzing civil efficacy and satisfaction about public designs with the cases in Daegu City. For this, the meanings of public designs of regional local government were reviewed through the previous studies and theories about them. And then, the analysis model was set based on them, and civil efficacy and satisfaction on public designs and factors of civil satisfaction were analyzed. The data for the analysis were collected from the surveys on Daegu citizens who use the public designs there, and frequency analysis, ANOVA, and multople regression analysis were conducted. The analysis results are as follows. First, for civil efficacy about public designs, public spaces were highest in park. By area, Chilgok and Palgong were higher while Dalseong and the downtown Daegu were lower. Second, for public buildings, public government buildings showed the highest values. By area, Chilgok and Palgong were higher while Dalseong and the downtown Daegu were lower. Third, for public visual media, traffic-related visual media were higher. By area, Suseong and Palgong were higher while Dalseong was lower. Fourth, for public facilities, road facilities were higher. By area, Suseong showed the highest. Fifth, for outdoor advertisements, those attached on buildings were higher, and Wolbae and Suseong were higher by region. Sixth, for the factors of the civil satisfaction about public designs, public spaces were highest and then public facilities and public buildings followed in order.

스노우파크 공조 및 폐열회수 시스템

김영한(Kim Young Han),박성빈(Park Sung Bin),정성화(Jung Sung Hwa),조현근(Jo Hyun Guen),조종선(Cho Jong Sun) 대한설비공학회 2013 대한설비공학회 학술발표대회논문집 Vol.2013 No.6

The presentation is the HVAC system in the Goyang ONEMOUNT snow park. The content consist of Architectural overview, design criteria, heat source equipment and air-conditioning system and waste recovery system explanation.

Effect of Plant Growth Regulators on Clonal Production through Basal Stem Explant Cultures of a Phalaenopsis Hybrid

Jo,Man-Hyun,Ham,In-ki,Park,Sang-kyu,Seo,Gwan-Seok,Han,Gyu-Heung,Woo,In-Shik 한국자원식물학회 2003 Plant Resources Vol.6 No.2

This study was conducted to develop the clonal propagation technique through in vitro culture using basal stem explants in Phalaenopsis hybrid grown in vitro. The highest frequency of protocorm-like body (PLB) formation was obtained when basal stem explants were cultured on VW medium containing 30g/L sucrose, 500 mg/L activated charcoal, 150 ml/L coconut water, 1 mg/L NAA, 5 mg/L 2iP and 2.5g/L gel rite. PLBs transferred to Hyponex medium were regenerated to plantlets. Plantlets transferred to plastic pots containing spagnum moss were developed and successfully acclimatized under greenhouse. The flower was bloomingly opened in plants regenerated from basal stem explants. The flower was not different from both mother plant and plant induced through clonal propagation of Phalaenopsis hybrid.

잡초성벼의 superoxide dismutase cDNA cloning과 재배벼로의 형질전환

박상규,박종석,이승인,서석철,김병극,조윤래,서학수 한국환경농학회 2002 한국환경농학회지 Vol.21 No.2

냉해나 한발등의 환경스트레스에 대해 저항성을 유발하는 유전자를 환경스트레스에 강한 잡초성벼로부터 선발하고 이들 유전자를 재배벼에 도입하여 도입유전자 산물의 과량 발현을 통해 냉해나 한발 등에 대한 저항성이 향상된 벼를 선발하고자 하였다. 잡초성벼인 Bhutan 14Ad로부터 냉해 및 한발 저항성 유전자로 알려진 superoxide dismutase (SOD) cDNA를 분리하고자 mRNA를 분리하고 이 분리된 mRNA를 이용해 reverse transcriptase PCR방법으로 SOD cDNA를 cloning 하였다. 그 결과 2종의 SOD cDNA가 cloning되어 SOD-A, SOD-B로 명명하였다. 이들 cDNA의 염기서열을 결정한 결과 이들은 아미노산 서열 상동성이 88.4%를 나타내었으며, SOD-A는 oryza sativa 계열의 Cu/Zn SOD유전자인 GenBank accession No. L36320와 99.3%로 동일하였으며, SOD-B는 accession No. D01000과 100% 동일하였다. 이들 SOD-A와 SOD-B cDNA를 재배벼인 낙동벼에 형질전환하여 형질전환체 벼를 선발하였으며, 이들 형질전환체 벼의 냉해저항성 및 한발저항성 검정을 통해 저항성이 향상된 형질전환체 벼를 선발하고 있다. Two different cDNA clones for superoxide dismutase (SOD) were isolated from an weedy rice variety (Oryza sativa, cv. Bhutanl4Ad) and were introduced into a cultivated rice variety (Oryza sativa, cv. Nakdong) in order to develop the environmental stress-resistant rice plants. Sequence analysis of the cloned cDNAs indicated that the deduced amino acid sequence of SOD-A is 88.4% identical to that of SOD-B. Furthermore, the nucleotide sequence of SOD-A is 99.3% identical to that of a Cu/Zn SOD gene of Oryza sativa (GenBank accession No. L36320). The nucleotide sequence of SOD-B was identical to that of the previously published SOD gene (Accession No. D01000). A cultivated rice variety, Nakdong-byeo, was transformed with chimenc SOD genes containing a actin promoter of rice and pin2 terminator using a particle bombardment technique. Transformed calli were selected on an selection medium containing phosphinothricin (PPT). Transgenic rice plants were regenerated from the PPT-resistant calli. PCR analysis with genomic DNAs from transgenic plants revealed that transgenes are introduced into rice genome.

퇴원한 정신분열병 환자의 외래 통원 치료에 미치는 요인

박기국,원승희,김상헌,김휘동,강병조 대한생물치료정신의학회 1998 생물치료정신의학 Vol.4 No.2

목적 : 저자는 외래 통원 치료를 지속적으로 받는 환자들과 중단한 환자들의 현황을 조사 비교했다. 그리고 외래 통원 치료를 지속적으로 받는 환자들 중 투약 약물 종류에 따른 치료 순응도에 영향을 미칠 수 있는 변인들을 비교했다. 연구 대상과 방법 : 첫 번째 1997년 4월 1일부터 1998년 4월 30일 동안 퇴원한 정신분열병 환자 140명을 대상으로 자료를 조사한 후 분석했다. 두 번째 1998년 5월 18일부터 1998년 6월 17일까지 한달 동안 외래를 방문한 후 순응도 요인에 관한 설문지의 항목을 작성한 46명 환자의 자료를 분석했다. 결과 : 외래 통원 치료를 지속적으로 받는 환자군과 통원 치료를 중단한 환자군을 비교했을 때, 성별, 연령, 교육 수준, 결혼 여부, 직업, 종교, 정신분열병 아형, 발병 연령, 유병 기간, 입원 횟수, 복용 약물들의 하루 총복용 횟수에서 통계학적으로 의미 있는 차이는 없었다. 퇴원 당시 clozapine을 투약했던 환자들에서 외래 치료지속율이 가장 높게 나타났다. 외래 통원 치료를 받는 환자들의 투약 약물 종류군에 따라 경제적 곤란도, 교육 수준, 유병 기간, 입원 횟수에서 유의한 차이가 있었다. 약물 종류군(clozapine, risperidone, typical anti-psychotics)에 따라 경제 상태, 향후 기대 치료 기간, 약물에 대한 인식도, 약물 효과에 대한 기대, 현재 약의 부작용, 약물의 부작용 경험도, 성별, 연령, 결혼 여부, 직업, 종교, 정신분열병 아형, 발병 연령, 1일 약물 복용 총 횟수의 차이가 없었다. 결론 : 클로자핀 약물을 투약한 환자들이 다른 종류의 항정신병 약물 투약 환자들에 비해 외래 통원 치료를 지속적으로 받는 비율이 높았다. Objectives : The authors compared the status of discharged schizophrenics between who are continuously followed and who are not in the treatment. Also we compared compliance factors among administered drug groups of the follow-up schizophrenics. Methods : First, we surveyed and analysed one hundred-four schizophrenics after discharge. Second, we analysed the questionnaires which were written by the forty-six follow-up patients who were asked about compliance factors. Results : There were no significant differences between patients who are continuously follow-up and who are not in the treatment on sex, age, educational level, marriage, occupation, religion, subtypes of schizophrenia, age of onset, duration of illness, admission rate, and complexity of drug administration methods Clozapine administered group had higher follow-up rate than that of other antipsychotics(rispendone and typical antipsychotics) administered groups among the discharged schizophrenics. Among the follow-up patients, there were significant differences between atypical antipsychotics patients and typical antipsychotics patients on economic difficulty, educational level, duration of illness, admission rate. There were no significant differences on the other of demographic and psychiatric characteristics. Conclusion : Clozapine administered group had higher follow-up rate than that of ther antipsychotics administered groups among the discharged schizophrenics.

동일한 국제예후지표(International Prognostic Index)를 나타내는 미만성 대형 B-세포 림프종에서 Bcl-2와 p16의 임상적 중요성

박상은,박수진,곽승근,박남숙,천재민,윤환중,조덕연,김삼용,김진만 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

In Korea, malignant lymphoma is a common cancer, comprising about 2.7% of all malignant neoplasm. Diffuse large B cell lymphoma is the most common lymphoma, representing about 50% of all Non-Hodgkin's lymphoma. Diffuse large B-cell lymphoma is usually considered as heterogeneous group of neoplasms rather than a single clinicopathological entity. Clinical prognostic systems, including the International Prognostic Index (IPI), although useful to assess overall prognosis, embrace patients with heterogeneous prognoses. But International Prognostic Index scoring system is not sufficiently predict the prognosis. It is likely that the prognostic assessment of patients with diffuse large B-cell lymphomamight be improved by using biological features. Bcl-2 protein and p16 protein expression is recognized as useful biologic markers predicting the prognosis of patients with diffuse large B-cell lymphoma. To determine the clinical significance and prognostic value of bcl-2 and p16 proteins expression patterns, we studied 18 patients with de novo DLBL, whose archival pathology specimen were available for immunohistochemistry studies, atChungnam National University Hospital from September 1992 to December 2000. Archival specimens from each patient were immunostained with respective antibodies for bcl-2, p16. The results are as follows; 1) The median age was 54(rage : 37-69). There were 12 male patients(66.7%) and 6 female patients(33.3%) The 'B' symptom was abscentin all patients. The stages were as follows : Ⅰ, 2 patient(11.1%), Ⅱ, 10 patient(55.6%), Ⅲ, 4patient(22.2%) and Ⅳ, 2patient(11.1%). 3 patients(16.8%) had the elevated LDH level, 14 patients(77.8%) had the normal LDH level and 1 patients(5.6%) was not identified the LDH level. 2 patients(11.1%) had the bulky disease and 16 patients(88.7%) had no bulky diease. The distribution of ECOG status were O, 2 patients(11.1%c), 1, 14patients(77.8%) and 2, 2patients(11.1%). 2) Theimmunohistochemistry results are as follows bcl-2:+,10 patients(55.6%), bcl-2:-, 8patinets(44.4%), p16:+,3 patients(16.7%), p16:-, 15patients(83.3%) 3) After a median follow UP durations of 67 months, the median survival time was 57 months with a rage of 7-100+ months. 5-years overall survival rates was 44% by Kaplan-Meier method. 4) Reduced overall survival was demonstrated in the patients who expressed bcl-2 protein(P=0.0174). 5-year overall survivial rate was 12%(bcl-2 expression) versus 88%(no bcl-2 expression) 5) Among diffuse large B-cell lymphoma patients with IPI score 0-1, reduced overall survival was demonstrated with bcl-2 expression(P=0.023). 5-year overall survival rate was 18%(bcl-2 expression group) versus 100%(no bcl-2 expressiongroup) 6) Median survival durtation of diffuse large B-cell lymphoma patients negative for p16 expression was 57 months whereas p16 postive patients' median survival duration was not reached(P=0.4478). In diffuse large B-cell lymphoma patients with identical IPI scores, bcl-2 expression had additional prognostic value.

ZnS:Cu,Cl형광체의 제조와 발광특성

박조용,한상도,김병권,정영호,S. P. Khatkar,Liang, Yu Jun 경북대학교 센서기술연구소 2002 센서技術學術大會論文集 Vol.13 No.1