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      • KCI등재

        Correlation Between Primary Si and Silicide Refinement Induced by Ultrasonic Treatment of Multicomponent Al–Si Alloy Containing Ti, Zr, V, and P

        Jae‑Gil Jung,Young‑Hee Cho,Tae‑Young Ahn,Jae‑Hee Yoon,Sang‑Hwa Lee,Jung‑Moo Lee 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.5

        The correlation between primary Si and silicide refinement induced by ultrasonic treatment (UST) of multicomponent Al–Sialloy containing Ti, Zr, V, and P was investigated. UST significantly refined the primary Si phase owing to cavitation-inducedwetting and deagglomeration of MgAl2O4particles. Lowering the UST finish temperature caused deterioration of the degreeof primary Si refinement, instead leading to silicide refinement. Cavitation-induced silicide nucleation on wetted MgAl2O4consumed the MgAl2O4particles, particularly in the case of primary Si nucleation. Similarly, the formation of an AlP phaseon the silicide phase reduced the nucleation efficiency of the AlP phase. Poisoning of the MgAl2O4and AlP phases by thesilicide phase was responsible for the deterioration in primary Si refinement. Room-temperature tensile strength and hightemperatureelongation were increased by UST and were dependent on the size of primary Si.

      • KCI등재

        정안침요법(整顔鍼療法)을 응용하여 호전된 후천성 사경환자 치험 2례

        박서영,김재수,홍의재,이윤경,이봉효,임성철,정태영,이경민,Park, Seo-Young,Kim, Jae-Su,Hong, Eui-Jae,Lee, Yoon-Kyoung,Lee, Bong-Hyo,Lim, Seong-Chul,Jung, Tae-Young,Lee, Kyung-Min 대한침구의학회 2008 대한침구의학회지 Vol.25 No.4

        Objectives : This report intended to estimate effects of Jung-an acupuncture on the acquired torticollis caused by muscle contraction. Methods : The patients were treated by Jung-an acupuncture, herb medication and Physical treatment daily. The improvement of the patients was judged by Toronto Western Spasmodic Torticollis Rating Scale(TWSTRS), Tsui's score and Visual Analogue Scale(VAS). Results : After 7 days of treatment, the 2 patients' neck pain and cervical movement were improved. Also, TWSTRS score, Tsui's score and VAS were all reduced. Conclusions : As the Jung-an acupuncture's theological base is organized with meridian theory and myofacial release therapy, We considered the Jung-an acupuncture is effective not only for the skin disease but also for the muscle problem such as torticollis.

      • 바이오매스로부터 생산한 바이오차에 의한 수질오염물질 흡착 : Adsorption of Water Pollution by Biochar Produced from Biomass

        박윤,정수연,정은서,신윤정,이은주,이재원 전남대학교 농업과학기술연구소 2022 농업생명과학연구동향 Vol.60 No.-

        Biochar is produced from lignocellulosic biomass (wood, agricultural and forestry waste, etc.) through thermal decomposition at high temperature. Water pollution (pesticides, dyes, heavy metals, and volatile organic compounds [VOCs]) can be efficiently removed by biochar. In particular, waste biomass is typically used as fuel or thrown away; thus, it is necessary to determine a valuable utilization for it. The process of biochar production is simple and suitable for the production of porous structures. In this paper, 1) biochar production and its characteristics based on biomass types, 2) research trends on the adsorption of water pollution (pesticides, dyes, heavy metals, VOCs) on biochar, and 3) expected effects are discussed.

      • 급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예

        오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1

        The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.

      • SCOPUSKCI등재

        Insulin resistance mediates high-fat diet-induced pulmonary fibrosis and airway hyperresponsiveness through the TGF-β1 pathway

        Park, Yoon Hee,Oh, Eun Yi,Han, Heejae,Yang, Misuk,Park, Hye Jung,Park, Kyung Hee,Lee, Jae-Hyun,Park, Jung-Won Nature Publishing Group UK 2019 Experimental and molecular medicine Vol.51 No.5

        <▼1><P>Prior studies have reported the presence of lung fibrosis and enhanced airway hyperresponsiveness (AHR) in mice with high-fat-diet (HFD)-induced obesity. This study evaluated the role of TGF-β1 in HFD-induced AHR and lung fibrosis in a murine model. We generated HFD-induced obesity mice and performed glucose and insulin tolerance tests. HFD mice with or without ovalbumin sensitization and challenge were also treated with an anti-TGF-β1 neutralizing antibody. AHR to methacholine, inflammatory cells in the bronchoalveolar lavage fluid (BALF), and histological features were evaluated. Insulin was intranasally administered to normal diet (ND) mice, and in vitro insulin stimulation of BEAS-2b cells was performed. HFD-induced obesity mice had increased insulin resistance, enhanced AHR, peribronchial and perivascular fibrosis, and increased numbers of macrophages in the BALF. However, they did not have meaningful eosinophilic or neutrophilic inflammation in the lungs compared with ND mice. The HFD enhanced TGF-β1 expression in the bronchial epithelium, but we found no differences in the expression of interleukin (IL)−4 or IL-5 in lung homogenates. Administration of the anti-TGF-β1 antibody attenuated HFD-induced AHR and lung fibrosis. It also attenuated goblet cell hyperplasia, but did not affect the AHR and inflammatory cell infiltration induced by OVA challenge. The intranasal administration of insulin enhanced TGF-β1 expression in the bronchial epithelium and lung fibrosis. Stimulating BEAS-2b cells with insulin also increased TGF-β1 production by 24 h. We concluded that HFD-induced obesity-associated insulin resistance enhances TGF-β1 expression in the bronchial epithelium, which may play an important role in the development of lung fibrosis and AHR in obesity.</P></▼1><▼2><P><B>Obesity: A trigger for asthma onset</B></P><P>Insulin resistance may be an important causative factor underlying the increased risk of asthma and other respiratory issues in obese individuals. Obesity doubles the likelihood of developing asthma, with symptoms that are more difficult to control than in non-obese patients. The connection between these conditions is poorly understood, but researchers led by Jung-Won Park, Yonsei University College of Medicine, Seoul, South Korea, have identified a potential mechanism. They demonstrated that a signaling molecule called TGF-β1 contributes to airway sensitivity and tissue scarring in a mouse model of diet-induced obesity. Subsequent experiments showed that treatment with insulin also gives rise to increased TGF-β1 production in the mouse lung. Since insulin resistance is a common feature of obesity, resulting in abnormally high levels of circulating insulin, this could also account for the increased risk of respiratory problems.</P></▼2>

      • 중량물 운반시 잡기유형과 부하단계에 따른 생리학적 연구

        윤양진,이훈식,윤길환,정미라,이재규,이중숙,서국웅 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

        The purpose of this study was to examine physiological changes of the body according to various weight loads and the holding during carrying object. The experiments were conducted with utilizing physiological analyses for five male and five female adults as subjects. The results were as followed. 1. Any significant difference was not shown in heart rate, ventilation and amount of oxygen uptake of male subjects in the case of no load and 5kg. And also no significant difference was shown in expiratory exchange ratio of male subjects of no load, 5kg and 10kg, but in other measure items and other stages of weight was shown. 2. Significant differences were shown in heart rate, ventilation, defluxion of carbon dioxide, oxygen uptake per body weights, respiratory exchange rate, respiration rate and all other measure items of female subjects in all stages of load. 3. In the MMH job, there was no influence on male subjects up to 5kg loads, but there was an significant difference in male subjects in load walking from 5kg. It shows that even in 5kg weight MMH work, female subject's expiratory function was influenced. 4. 10kg load was the limit weight of female subjects and 15kg was of male subjects when they walked on treadmills with 4km/h velocity for 3 minutes, holding loads in the right and vertical types.

      • 有限變形率 壓密理論에 의한 軟弱 粘土의 一次元 壓密에 관한 數値 解析的 연구

        鄭潤和,李明旭,兪南在 江原大學校 産業技術硏究所 1991 産業技術硏究 Vol.11 No.-

        A numerical study was performed to investigate characteristics of one-dimensional consolidation of soft clay. Results of consolidation tests with the remolded normally consolidation clay of having a very high initial void ratio were analyzed by using the numerical technique of finite difference method based on the finite strain consolidation theory, to evaluate consolidational characteristics of soft clay under surcharges on the top of clay. On the other hand, a numerical parametric study on soft clay consolidated due to its self-weight was also carried out to find its effect on one-dimensional consolidation. Terzaghi's conventional consolidation theory, finite strain consolidation theories with linear and non-linear interpolation of effective stress-void ratio -permeability realtion were used to analyze the test results and their results were compared to each other to figure out the difference between them.Therefore, the validity of theories was assessed.

      • 地下掘鑿時 隣接地盤의 沈下豫測

        정상국,심태섭,이재윤 朝鮮大學校 建設技術硏究所 2000 建設技術硏究 Vol.20 No.1

        This analysis of some empirical equations as well as measured value was carried out for comparison between instrumental valve attained at the site excavation in urban area in korea. And the follow come to conclusion that : 1) On comparing each other among themselves was estimated by FEM 8.54cm. Peck 21cm. Clough 6cm, Fry 16cm moreover actual values were measured with 12.23cm and the differentiation of each other was some appeared. 2) On comparisons horizontal displacement appeared by excavation with FEM was showed maximum horizontal displacement at depth 8m and the FEN showed some more than actual value. 3) In result, the clough method was controlled by displacement with carrying out excavation also excavation depth of 0.28 percent easily.

      • KCI등재

        저수탱크의 혼화특성 평가

        윤재흥,정혜원,오정우 대한상하수도학회 2003 상하수도학회지 Vol.17 No.1

        Storage tanks have two types of function. One is to maximize the disinfection capability by inducing plug flow, and the other is to regulate the water quality by mixing flow completely. Hence the mixing indices to represent the flow characteristics in tanks are required to identify if the tank performs its function well. As a result of evaluating the existing indices with fluoride-tracer and dye tests, T_10/T and T_90/T_10 proved relatively good indices. However, T_10/T showed some limits to representing the characteristic of residence time distribution, and T_90/T_10 had too wide range of the values to be easily used for assessing the flow characteristics. An index proposed in this study can properly represent both the completely mixed and plug flows as well as short-circuit flow, and can be used as an index of assessing mixing characteristics.

      • KCI등재

        젖소 말초혈액 림프구로부터 소백혈병 바이러스 배양 및 전자현미경적 관찰

        윤순식,박중원,변재원,강문일,유한상,한홍율 韓國電子顯微鏡學會 2005 Applied microscopy Vol.35 No.1

        국내 젖소의 54.2%가 BLV에 감염되어 있지만 현재까지 국내에서는 소백혈병 바이러스 (BLV) 입자를 확인한 연구 보고가 없기 때문에 BLV 항체 양성 소의 말초혈액림프구를 배양, BLV를 발현시켜 전자현미경으로 바이러스 입자를 검출하였고 배양조건에 따른 바이러스 발현율 및 발현 시간을 비교하였다. 검사 결과 전형적인 C-형 바이러스를 확인할 수 있었으며 BLV 단크론 항체를 이용한 면역염색결과 BLV 항원 양성으로 확인되었다. BLV 는 대부분 세포 외부에 분포하고 있었으며 세포질 막에서 생성, 발아되어 나오는 것도 관찰되었다. 전체 바이러스의 크기는 90~100 nm였으며 nucleocapsid는 40~60nm였다. 소태아혈청 (FBS)과 T- 및 B-림프구 분열촉진물질(mitogen)을 각각 첨가하여 배양한 결과 두 군 모두에서 BLV 발현이 확인되었다. Lipopolysaccharide 첨가군은 배양 12시간, Conconavalin A 첨가군은 배양 24시간에 각각 림프구의 10%에서 바이러스가 관찰되었다. 또한 FBS만 첨가한 군과 FBS와 mitogen을 모두 첨가하지 않은 군에서도 관찰되었으나 바이러스의 수는 적었다. 본 연구에서 확립된 BLV 배양 기법을 활용하면 BLV에 감염된 소 중 바이러스를 발현하는 소, 즉 전파능이 있는 개체를 찾아내어 우선적으로 도태할 수 있기 때문에 BLV 감염으로 인한 피해를 막는데 효과적으로 이용될 수 있을 것으로 사료된다. Many studies have been performed on the bovine leukemia virus (BLV) since bovine leukosis had been reported in 1968 in Korea. However, there was no report on the ultrastructural examination of BLV. An attempt to detect C-type viral particles in the cultured peripheral blood lymphocytes of Holstein-Friesian dairy cattle, was made to determine whether in vitro viral expression might be used as a reliable method to identify the cow which is likely to transmit BLV. In transmission electron microscopic (TEM) examination, the virus particles were found predominantly outside of the lymphocytes even though a few particles were also observed within the membrane bound cytoplasmic vacuoles. All of them were C-type particles consisting of a central, electron-dense core separated by a clear area from a limiting envelope with a unit membrane structure. Virus particles were easily detected in the lymphocyte which was cultured with medium supplemented with either T-lymphocyte mitogen (conconavalin A) or B-lymphocyte mitogen (lipopolysaccharide). Identical viral particles, although fewer, were also consistently present in the lymphocytes cultured with medium which was containing foetal bovine serum (FBS) only and which was containing neither FBS or mitogen. By contrast, no virus particle was detected in extensive examination of lymphocytes before culture. In conclusion, the BLV cultivation and detection methods established in this study could be used as a tool to identify and eliminate the cattle which can transmit the BLV.

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