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정중식,권운용,김규석,임용수,이중의,서길준,윤여규 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3
Background: Most febrile neutropenic patients are treated in an aggressive manner. However, identification of low-risk patients may enable clinicians to administer risk-based treatment. The object of this study is to certify the factors associated with increased risk at the time of visiting the emergency department. Methods: This is a retrospective study. We reviewed the medical records of 101 febrile neutropenic patients who had visited the emergency department of Seoul National University Hospital from January 1998 to August 1999. We assumed 22 risk prediction factors that could be assessed at admission to the emergency department and 5 factors that could be assessed during treatment course. To find independent risk-prediction factors, we analyzed these factors respectively by using multiple regression analysis. Results: Tachycardia(aOR=136.5), altered mentality(aOR=28.8), decreased renal function(aOR=20.1), and significant comorbidity(aOR=17,2) are the independent factors associated with higher mortality. Altered mentality(aOR=31.6) and decreased renal function(CCr < 75㎖/min, aOR=5.4) are those associated with a higher incidence of septic shock. Independent factors associated with persistent(more than 3 days) fever are the early(within 10 days) onset of fever after last chemotherapy(aOR=8.8) and the existence of new pulmonary infiltrates on a simple chest X-ray(aOR=4.3). Conclusion: The stability of vital signs, the change of mentality, the renal function, the existence of significant comorbidity, the existence of new pulmonary infiltrates, and the rate of neutropenia are clinically useful risk-prediction factors in febrile neutropenia at the time of visiting the emergency department.
만화 과제를 이용한 정신분열병 환자의 사회인지 능력의 측정
오정은,나명현,하태현,신용욱,노규식,홍순범,이경진,신민섭,이영호,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3
Objectives : This study is to investigate the hypothesis that schizophrenic patients have difficulty in inferring mental state of others. Methods : Twenty schizophrenic patients and twenty normal subjects were administered to the Cartoon Task required inferring the character's intention in a given context. Results : The schizophrenic patients showed a statistically significant impairment in the Cartoon Task. Both groups chose the card depicting a frequent everyday action significantly more rather than the similar card to the last picture in each story for wrong answers. Conclusion : These preliminary results suggest that schizophrenia is associated with a specific deficit of the cognitive ability referred to as social cognition, and this deficit can be detected not only in the acute phase as found in previous research studies, but also in remission. Also when subjects fail to appreciate what is going on in the minds of other people, they seem to rely on a socially familiar experience.
A new mid-late maturing japonica rice variety Hyeonpum with a good grain quality and eating quality
Jeong-Ju Kim,Woon-Chul Shin,Mun-Sik Shin,Ki-Yeong Kim,Bo-Kyeong Kim,Jeong-Kwon Nam,Jong-Cheol Ko,Hyeon-Su Park,Ki-Yong Ha,Man-Kee Baek,So-Hyeon Baek,Young-Jun Mo,Woo-Jae Kim,Hyeon-Jung Kang,Jae-Kwon K 한국육종학회 2013 한국육종학회 심포지엄 Vol.2013 No.07
‘Hyeonpum’ is a new japonica rice variety developed by a cross breeding between Iksan469 having a good canopy architecture and Sindongjin and Musashino 7 having a good eating-quality with a view to develop a new variety having high quality of grain and palatability by the rice breeding team of Rice Breeding and Cultivation Research Division, Department of Rice and Winter Cereal Crop, NICS, RDA in 2012. The heading date of this variety is August 18 and later than that of check variety, Nampyeongbyeo, by four days. ‘Hyeonpum’ has 74cm of culm length and 101 spikelets per panicle. This variety showed resistance to bacterial leaf blight and rice stripe virus, but susceptible to leaf blast and planthoppers. The milled rice of this variety exhibits translucent and very clear non-glutinous endosperm. ‘Hyeonpum’ has much better palatability of cooked rice than that of Nampyeongbyeo. The whole grain rate of milled rice and milled rice recovery of ‘Hyeonpum’ are slightly higher than those of Nampyeongbyeo as 91.8% and 75.2% respectively. The yield of ‘Hyeonpum’ is 5.6 MT/ha in milled rice. ‘Hyeonpum’ could be adaptable to the southern part plain area of Pyeongtaek and southwestern costal areas in Korea.
간경변 환자의 정맥류 출혈에서 Octreotide의 지혈효과
권운용,정중식,김규석,김성혜,신상도,이중의,서길준,윤여규 대한응급의학회 2001 대한응급의학회지 Vol.12 No.1
Purpose: This study was conducted to confirm the effects of octreotide in patients with variceal bleeding. Methods: We performed a retrospective analysis of 26 patients with variceal bleeding, who visited the Emergency Center of Seoul National University Hospital from January 1st to June 31st,1996, the control group, and a prospective analysis of 28 patients with variceal bleeding, who visited the Emergency Center of Seoul National University Hospital from March 1st to August 31st, 1999, for the octreotide-infused group. The octreotide-infused group recieved a continuous infusion of octreotide, 25㎍/hr, for 5 days after an initial bolus of 50 ㎍. When active bleeding continued over 1 hour, over 5 pints of packed-RBC were needed for transfusion within 24 hours, or when the systolic blood pressure was under 90mmHg, a ballon tamponade with Sengstaken-Blackemore tube was used. T-test and X2 test were used for statistic at analysis (p<0.05). Results: Forty-one patients were male(octreotide-infused group 22, control group 19) and 13 were female(octreotide-infused group 6, control group 7). The mean age was 55 years(octreotide-infused group 56 years, control group 52 years). There were no significant differences in vital signs, hemoglobin/hematocrit levels, and Child-Pugh's classifications between the octreotide-infused group and the control group initially. There was a significant difference in the rates of early bleeding control within 24 hours(p<0.05), but there were no significant differences in the rates of rebleeding, mortality within 1 week, and use of a balloon tamponade. Conclusion: Variceal bleeding is a serious complication of liver cirrhosis and has a high mortality rate. Octreotide is an effective vasoactive agent for control of early bleeding, Thus, octreotide should be used first before endoscopic definitive therapies, to stabilize the vital signs of patients and to secure a field for endoscopic procedures.
Development of BPH Resistant Rice Variety for Environmental Friendly Cultivation
Woon-Chul Shin,Ki-Young Kim,Jong-Cheol Ko,Young-Jun Mo,Jeong-Kwon Nam,Mun-Sik Shin,Bo-Kyeong Kim,Jae-Kwon Ko 한국작물학회 2010 한국작물학회 학술발표대회 논문집 Vol.2010 No.04
BPH(Brown planthopper, Nilaparvata lugens Stål) is a major insect of rice and give a lot of damages around Korea, Japan and East-West Asia. BPH often causes heavy losses of up to 60% of rice crop yields in susceptible cultivars. Especially, increase of the environmental friendly cultivation in South Korea has caused the outbreak of BPH rapidly. But few resistant varieties in Korea have known until now. Utilization of R genes in breeding programs has been the most effective and economical strategy for controlling insect resistance. It is reported that Bph1 gene is located on a long side of chromosome 12 and linked to bph2 among reported 18 R genes. BPH resistant "Iksan529" was derived from a cross between HR22538-GHB-36-4(bph2) and Iksan471 at Department of Rice and Winter Cereal Crop, NICS, RDA. Culm length of Iksan529 is 74cm and it shows moderate resistance to blast, and wide spectrum resistance to bacterial blight pathogen(K1, K2, K3) and stripe virus. Especially, Iksan529 was identified bph2 gene using KPM2(co-dominant CAPS marker) and KPM4(resistant-associated marker). When Iksan529 seedling were infested at 2nd and 3rd instar stages of BPH nymphs(Bio-type 1), it showed resistance at one month after infest. Iksan529 will be tested local adaptability for 3 years and deveoped for environmental friendly cultivation.
제조공정최적화에 관한 실험적 연구 : 법랑욕조 제조공정을 중심으로
권오운,김우식 연세대학교 산업기술연구소 1991 논문집 Vol.23 No.2
The security of product quality in an enterprise plays an important part of heightening the competitive power externally, and also it induces the cost reduction by decreasing the internal failure costs by the systematic process control. The study proposed the comprehensive analysis model for the optimizing step and process of manufacturing process on the porcelainenameled bath-tubs by by using the 2n orthogonal array tables among the experimental design methods to improve the adhering property as the quality characteristics of them which is the key point in the security of quality. The verification experiment as a result of the manufacturing process optimization was performed, and the result of it was closely akin to the induced point estimate.
Kwon, Sik-Chol,Rha, Jong-Joo,Beck, Woon-Seung The Korean Vacuum Society 1997 Applied Science and Convergence Technology Vol.6 No.1
The attempt to enhance the strength of materials has been an important subject for materials engineering and scientists. The strength of materials is termed as the ability to support high load without excessive deformation and without breaking catastrophically. The control of dislocation densities and barriers to the movement of dislocations have been considered to be the important methods for the strengthening materials. One of the approaches is mechanical blocking of dislocations by alternately depositing material layers. The typical structure of materials is multilayered and laminated composites. The thickness of each layer is typically in the range of nanometer. Ton avoid confusion with other terminology they may be defined as microlaminate composite materials. The manufacturing process of multilayered laminate structure will be introduced. And the current theoretical theories will be reviewed in view of strengthening of microlaminte composite materials.