동종 골수이식 후 만성 이식편대숙주반응 환자에서 발생한 폐렴구균에 의한 수막뇌염 1예

신완식,김병욱,유진홍,김동집,김춘추,박종원,이종욱,김동욱,강문원,김양리 대한감염학회 1993 감염 Vol.25 No.3

Graft-versus-host disease (GVHD) is a frequent complication after bone marrow transplantation. Infectious complications are common in GVHD patients due to defect in cell-mediated immunity. A rare case of S. pneumoniae meningoencephalitis occured in a patient with extensive form of chronic GVHD after allogeneic bone marrow transplantation. He was immediately treated with full dosage of ceftriaxone and ampicillin. He suffered from various complications such as sepsis, acute renal failure, atelectasis, and seizure. Despite of aggressive treatment, he died probably due to renal shutdown and massive subacute cerebral infarction of left cerebral hemisphere. This report showed two unusual and rare features. First, the infection site was CNS rather than respiratory system. Second, the causative organism was S. pneumoniae, which is rare cause of CNS infection in immunocompromised patients.

달 탐사선의 발사 요구조건 및 임무궤도 사례연구

석병석(Suk, Byong-suk),민승용(Min, Seung-yong),권재욱(Kwon, Jae-wook),김창균(Kim, Chang-kyoon),문상만(Moon, Sang-man),최수진(Choi, Su-jin),구철회(Koo, Cheol-hea),김인규(Kim, In-kyu),류동영(Ryu, Dong-young) 한국항공우주연구원 2015 항공우주산업기술동향 Vol.13 No.2

시험용 달 궤도선의 발사 요구조건 사전 분석 단계로 최근 외국에서 발사한 달 탐사선의 발사 요구조건을 분석하였다. 일반적으로 달 탐사선의 발사 요구조건은 달 임무 궤도를 결정하는 중요한 요소이며, 또한 지구, 달, 태양의 상대적인 운동으로 인해 임무궤도 요구조건을 만족하는 발사 가능 시간이 주기적으로 반복되는 경향이 있다. 분석 결과 설정된 발사 요구조건들로부터 달 궤도선의 주 임무가 달의 남/북극 지역의 광학 관측 임을 간접적으로 알 수 있었다. 향후 우리나라 달 궤도선 발사 요구 조건 설정에 본 논문이 도움이 되길 기대한다. In the preliminary study on launch window requirement for Korea Path-finder Lunar Orbiter(KPLO), the recent foreign lunar orbiter’s lauch window requirement was analyzed. Normally, the launch requirements depends on the mission orbit. Based on the relationship between Moon, Earth, and Sun, the launch time will be available periodically to meet requirements. In this paper, it is understood that the launch window requirements come from payload mission requirements to take picture each poles of Moon. This paper might be a practical example to derive KPLO launch requirements in the future.

SCM415강의 침탄 표면처리 공정과 기계적 성질

김대욱,김문진,임병수 成均館大學校 科學技術硏究所 1998 論文集 Vol.49 No.2

The influence of plasma carburizing process on the surface hardness of SCM415 low-alloy steel (0.15% C) was investigated under the various process conditions of gas composition, gas pressure, plasma current density, temperature and time. The effective case depth was found to depend on the amount of methan gas containing carbon, thus the deepest case depth and the uniformity of hardeness were obtained under the 100% methan gas condition. The case depth increased with the higher plasma current density which could be increased in the higher gas pressure, because the surface carbon content depends on plasma current density. The effective plasma carburizing temperature of SCM415 steel was found to be higher than 850℃, and the case depth was proportional to the square root of carburizing time under the same current density. The bending fatigue strength of plasma carburized specimen is higher than those of as-received specimen and reheat-quenched specimen. High cycle fatigue and dry wear characteristics of vacuum carburized low alloy steel, SCM415(0.15% C), were evaluated after various heat treatments including direct quenching, single reheat quenching and sub-zero treatment. Comparing the fatigue and wear characteristics of carburized specimens to those of hot annealed or reheat quenched specimens, the wear resistant property as well as bending fatigue limits of vacuum carburized steels were substantially superior to other heat treated steels. Test results indicated that the carburized and reheat treated specimens have higher fatigue limits than the carburized and direct-quenched specimens and the specimens followed by sub-zero treatment. The wear volumes of sub-zero treated specimens with higher surface hardness show slightly lower values than those of non sub-zero treated specimens. This is attributed to the reduction of retained austenite amount of the surface and an increase of surface hardness by the sub-zero treatment effect.

말단 비대증환자에서 Somatostatin Analog 약물요법

이경욱,남문석 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.5

어음행위의 表見代理에 관한 再檢討

李鴻旭,金汶在 대구효성가톨릭대학교 1991 연구논문집 Vol.43 No.1

악성 갑상선 우연종의 임상상 및 초음파 소견의 진단적 가치

강한욱,김광원,이병완,강보현,김형훈,김범진,정재훈,민용기,이명식,이문규 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.5

연구배경: 최근 갑상선 초음파 검사의 빈번한 시행으로 갑상선 우연종의 발견이 증가하고 있다. 이러한 갑상선 우연종은 임상적으로 어떻게 접근하고 치료를 해야 하는지 적지 않은 문제가 되고 있다. 본 연구에서는 직경 1.5㎝ 이하의 갑상선 우연종의 유병률, 입상적 특징 및 초음파 특성, 그리고 가장 효율적인 진단적 접근에 대해 알아 봤다. 방법: 1999년 1월부터 2000년 12월까지 삼성서울병원 내과 및 일반외과로 갑상선 결절을 주소로 내원한 1457명을 대상으로 후향적 연구를 시행하였다. 우연히 발견된 직경 1.5㎝ 이하의 갑상선 결절을 가지는 환자들에서 갑상선 결절의 촉지 유무, 갑상선 기능검사, 항갑상선 항체, 갑상선 초음파 및 미세침 흡인세포검사, 99m^Tc 갑상선 스켄, 수술 조직검사 및 병기를 검토하였다. 결과: 분석한 갑상선 결절 1475예 중 갑상선 우연종의 유병률은 13.4%(198예)였다. 갑상선 우연종에서 악성률은 28.8%(57예)으로 나왔다. 양성 및 악성 갑상선 우연종에서 나이, 성별, 갑상선 기능검사, 결절 크기에는 의미 있는 차이는 없었다. 갑상선 스켄은 갑상선 우연종의 감별에 적합하지 않았다. 갑상선 결절의 초음파 지표 점수만이 양성 및 악석 갑상선 우연종의 감별에서 초음파 지표 점수의 민감도는 88.9%, 특이도는 74.4%, 양성 예측률은 92.4%로 나왔고 진단적 정환도는 85.5%였다. 갑상선암으로 수술을 받은 50명중 stage 1은 34명, stage 2는 6명, stage 3은 10명으로 대부분의 악성 갑상선 우연종은 낮은 TNM 병기로 나타났으나, 상당수에서는 국소 침범의 소견을 보였다. TNM 병기의 3기 환자 전부는 45세 이상이였고, 주로 갑상선암의 피막 침범에 의한 것이었다. 임파절 전이는 6명의 환자에서 나왔다. 결론: 악성 갑상선 우연종은 비교적 흔히 접할 수 있는 질환이며 양성 우연종과는 임상적으로 구별이 안 된다. 악성 갑상선 우연종은 발견 당시 대부분 낮은 병기이나, 갑상선의 피막 침범 및 임파절 전이가 상당수에서 발견되었다. 갑상선 우연종의 초음파 소견은 향후의 진단 방향을 제시하는 중요한 길잡이가 될 수 있다. 초음파 지표 점수 2점 이상의 갑상선 우연종에서만 초음파 유도 미세침 흡입검사를 권장한다. Background: High-resolution ultrasonography has made the detection of asymptomatic small thyroid possible. Recent increases in the detection of incidentalomas have created a clinical dilemma on how to properly manage such incidental nodules. We investigated the prevalence, clinical and ultrasonographic characteristics, and optimal diagnostic approach toward incidentally detected benign and malignant thyroid nodules of less than 1.5㎝ in size. Methods: A retrospective review was undertaken on the 1,475 patients who had visited Samsung Medical Center, Seoul Korea between January 1999 and December 2000. The review consisted of a physical examination of the thyroid gland, thyroid function test, antithyroid antibodies, thyroid ultrasonography, fine-needle aspiration biopsy, pathology and TNA staging of the incidentally detected thyroid nodules of less than 1.5㎝ in size. Results: The prevalence of thyroid incidentalomas was 13.4% and the malignancy rate within them was 28.8%. There were no significant differences in age, sex, thyroid function test and size between the benign and malignant incidentalomas. Ultrasonographic characteristics showed meaningful diagnostic value for the detection of malignancy in incidentalomas. Most malignant incidentalomas were of a low stage. Conclusion: Occult thyroid cancers are fairly common finding. There are no clinical difference between benign and malignant thyroid nodules less than 1.5㎝; however, ultrasonographic findings can be used to decision of optimal management strategies (J Kor Soc Endocrinol 17:649∼656, 2002).

보존적 후두 적출술

엄재욱,황문섭 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Laryngeal cancer is known to show relatively good prognosis. Though primary object of laryngeal cancer treatment is to save patient's life, it is also important to support patient's quality of life by preserving laryngeal function. During the 1960s through 1980s, researches about anatomy of larynx were proceeded many innovative surgeons reported numerous small series of patients in which the indications and extent of resection of these basic techniques were extended in an attempt to manage larger lesions. Today, there is a variety of techniques available for selected laryngeal malignancies, with predictable functional and oncologic outcome based on analysis in the literature of many patients. Conservation laryngeal surgery is precision surgery and to achieve successful oncologic and functional results, the conservation laryngeal surgeon should have a firm grasp of the clinical assessment of laryngeal cancer and a complete understanding of the surgical techniques.

不定流 解析에 關한 硏究 : 差分法을 中心으로

申文燮,高秉旭 군산대학교 1990 群山水産專門大學 硏究報告 Vol.24 No.1

The unsteady flow in the river was calculated by the finite difference method. The results are follows. 1) When the explicit method are used in the unsteady flow, because of occurring the damping phenomena except Cr No. = 1, it is considerated to the stability. 2) In the results which analyze the unsteady flow by implicit F.D.M., the damping phenomena is smaller than the one by the explicit method.

중생공영론(衆生共榮論)

김문욱 국제문화학회 1991 역사와 사회 Vol.5 No.-

慶南 島嶼地域 井戶에 對한 環境衛生學的 調査硏究

鄭文植,李弘根,李容旭 서울大學校 保健大學院 1972 公衆保健雜誌 Vol.9 No.1

A study was carried out to find the sanitary condition of wells in Koje Island, Kyoungnam Province, from July 16, to July 30, 1971. Salinity was measured to check the seepage of sea water by the silver nitrate titration method and coliform groups were examined by the membrane filter method as well as the general sanitary state of wells and their surroundings. Main findings were as follows; 1. the average chloride ion concentration of 41 wells examined was 54.0ppm with the standard deviation of 31.8 which was below the maximum permissible concentration of 150.0ppm in drinking water. 2. the mean chloride ion at lower district wells was the highest of 69.9 ppm which looked to be influenced by the sea water. 3. no relation was found between the concentration of chloride ion and the pollution of wells which seemed to be more affected by the sanitary state of wells and their surroundings. 4. coliform groups were positive at 25 wells(61.0%) out of 41 and at 17 out of 21 of less than 2 m depth and no coliforms were found at the wells of more than 3 m one. Water-proof structure of 3 m depth was necessary to protect wells from pollution. 5. coliforms were found at all 15 wells within the 6 m distance from the pollution sources, but 3 out of 13 of more than 10 m one. 6. the rates of coliform positives were 92.8 percent at higher districts, 37.8 at lower ones and 27.2 at coastal ones.