농업인에서의 체내 잔류농약 검출

최수진,황상현,전사일,민원기,이선호,김성률,김영식,선우성,전태희,정태흠,Choi, Soo-Jin,Hwang, Sang-Hyun,Chun, Sa-Il,Min, Won-Ki,Lee, Seon-Ho,Kim, Sung-Ryul,Kim, Young-Sik,SunWoo, Sung,Jun, Tae-Hee,Chung, Tae-Heum 한국농촌의학지역보건학회 1998 농촌의학·지역보건 Vol.23 No.2

배경 : 농약의 사용이 보편화되면서 점차 그 사용량이 증가되고 있다. 저자들은 농한기의 농업인을 대상으로 국내에서 가장 많이 사용되는 맹독성 농약인 methyl bromide와 organophosphate compound의 농업인 체내 잔류 정도를 혈청 bromide 농도와 cholinesterase 활성도도 측정을 통해 조사하고자 하였다. 방법 : 농한기에 경상남도 산청군과 하동군에 거주하는 121명의 농업인을 대상으로 농번기의 농약사용에 관한 설문조사와 농약의 잔류정도를 측정하기 위한 혈액을 채취하였다. 대조군으로는 간 기능이 정상이며 B형 간염 항원이 없는 사람 중에서 연령과 성별에 맞게 무작위로 240명을 선별하였다. 농업인과 대조군에서 혈중 bromide는 혈청을 이용하여 gold chloride방법으로 구하고, cholinesterase는 colorimetric assay로 측정하였다. 대상 농업인중에서 간기능 검사가 이상 소견을 보이거나 B형 간염 항원 양성인 33명과 이에 해당하는 대조군 65명은 비교대상에서 제외하였다. 결과 : 정상인 240명을 대상으로 산정한 혈청 bromide 농도의 참고치는 72.9 ug/mL이하, 혈청 cholinesterase 활성도의 참고치는 1.6-15.9 U/mL 이었다. 정상인 175명의 혈청 bromide 농도는 $29.8{\pm}22.5\;{\mu}g/mL$, 혈청 cholinesterase 활성도는 $8.7{\pm}3.6$ U/mL이었다. 농업인의 혈청 bromide 농도는 $31.7{\pm}18.0\;{\mu}g/mL$로 대조군과 차이를 보이지 않았고, 혈청 cholinesterase도는 $10.9{\pm}4.2$ U/mL로 대조군에 비하여 유의하게 높았다. 농업인을 경작 면적, 농약 사용시 장갑 및 마스크 착용 유무에 따라 분휴류여 비교해 본 결과, 혈청 bromide 농도나 혈청 cholinesterase 활성도 차이가 없었다. 결론 : 농한기 농업이과 정상인을 비교해 보았을 때 methyl bromide 중독시 증가하는 혈청 bromide 농도는 차이가 없었으며, organophosphate compound 중독시 감소되는 cholinesterase는 농한기 농업인에서 대조군보다 높은 값을 보였다. 따라서 혈청 bromide 농도와 cholinesterase 활성도는 농한기 농업인에서 농약의 체내잔류 지표로 유용성이 낮다고 사료된다. The usage or agricultural chemicals is on the increasing tendency. Methyl bromide and organophosphate are the most widely used toxic agricultural chemicals in Korea. We try to set up the methods to detect the accumulation of these chemicals in Korean farmers. Blood samples were collected for 121 farmers of slack's season in February 1998. And survey about arable acreage and usage of the gloves and masks was also performed. Serum cholinesterase activities and bromide concentrations were measured with gold chloride method and colorimetric method. The reference ranges of serum cholinesterase activity and bromide concentration were 1.6~15.9 U/mL and below $72.9{\mu}g/mL$. Serum bromide concentrations of farmers and normal controls showed no differences. Serum cholinesterase activities of farmers were significantly higher than those of normal controls. According to the arable acreages and usage of the gloves and masks, serum bromide concentrations and cholinesterase activities showed no differences. In conclusion, serum cholinesterase activities and bromide concentrations showed no differences between farmers of slack's season and normal controls.

특수교사가 인식하는 자폐범주성장애 아동의 식행동 및 식품기호도와 영양교육 요구도

최수진,오지은,김유리,김유리,Choi, Su Jin,Oh, Ji Eun,Kim, Yu-Ri,Kim, Yuri 한국식생활문화학회 2021 韓國食生活文化學會誌 Vol.36 No.1

The purpose of this study was to provide basic information on the development of nutrition education programs to improve the mealtime behavior of children with autism spectrum disorder (ASD) by investigating the mealtime behavior and food preferences of children with ASD through the perception of special education teachers. Surveys were given to 108 special education teachers in special education schools in Korea regarding the demographic characteristics, nutrition education support needs, mealtime behavior, and food preferences of children with ASD. Most of the special education teachers responded that nutrition education in special schools had not been conducted properly and nutrition education for ASD children is necessary. Mealtime behavior analysis classified the behavior into three clusters: cluster 1, 'less problematic mealtime behavior'; cluster 2, 'general feature of autism'; cluster 3, 'difficulty in self-directed diet'. The age, eating habits, and food preferences were different according to each mealtime behavior cluster. Therefore, it will be necessary to develop a nutrition education program based on the characteristics of mealtime behavior.

SCV 가솔린 엔진의 운전조건에 따른 희박연소 특성

최수진,전충환,장영준,Choi, Su-Jin,Jeon, Chung-Hwan,Chang, Young-June 대한기계학회 2000 大韓機械學會論文集B Vol.24 No.2

Lean combustion in a SI engine is one of the best solution for the improvement of fuel economy and reduction of pollutant emission. In order to access a lean combustion engine, stable combustion at lean AlF ratio is needed. In this paper, the effect of fuel injection timing on lean misfire limit has been investigated in an MPI engine. To investigate the interaction of injection timing and intake flow characteristics, three different swirl generating SCV(swirl control valve) configurations were considered, and investigated their effects on lean misfire limit and torque at full load operation. Also the effects of spark timing on lean combustion has been investigated. Lean combustion has been examined and the results are reported in this paper. SCV B has been developed to satisfy the requirements of sufficient swirl generation to improve lean combustion and stable performance. It is found that injection timing, spark timing and intake air motion govern the stable lean combustion.

유동 강화형 밸브의 형상에 따른 정상 유동 특성

최수진,류기현,전충환,장영준,Choi, Su-Jin,Ryoo, Ki-Hyun,Jeon, Chung-Hwan,Chang, Young-June 대한기계학회 1999 大韓機械學會論文集B Vol.23 No.2

The flow characteristics of 2-valve and 4-valve cylinder heads with various blocked-valve were experimentally investigated in a steady flow rig. Effects of the blocked-valve configurations on flow coefficient, swirl and tumble intensity are studied. Compared to the conventional valve, the blocked valve in both cylinder heads have the much lower flow coefficient and the much higher intensity of swirl and tumble. Under the same size of blockage, the value of flow coefficient and swirl(or tumble) intensity were varied according to the position of blockage. Throughout these steady flow test the optimized positions of blockage in both cylinder heads were determined.

생쥐 난자의 효율적인 냉동보존 방법 확립을 위한 연구

최수진,김수경,김지선,조재원,전진현,변혜경,Choi, Su-Jin,Kim, Soo-Kyung,Kim, Ji-Sun,Cho, Jae-Won,Jun, Jin-Hyun,Byun, Hye-Kyung 대한생식의학회 2004 Clinical and Experimental Reproductive Medicine Vol.31 No.1

Objective: The purpose of this study was to evaluate the efficacy and effect of various cryopreservation method on the survival and the cytoskeletal stability of metaphase II mouse oocyte. Methods: Mouse ovulated oocytes were collected and cryopreserved by a modified slow-freezing method with 1.5 M 1, 2-propanediol (PrOH)+0.1 M sucrose or by vitrification using cryo loop and EM grid with 40% ethylene glycol+0.6 M sucrose. Four hours after thawing, intact oocytes were fixed and stained with fluorescein isothiocyanate (FITC)-conjugated monoclonal anti-$\beta$-tubulin antibody to visualize spindle and propidium iodide (PI) to visualize chromosome. Spindle morphology was classified as follows: normal (barrel-shaped), slightly and absolute abnormal (multipolar or absent). Results: Survival rate of the frozen-thawed oocytes in vitrification group was significantly higher than that of slow-freezing group (62.7% vs. 24.4%, p<0.01). Vitrification with cryo loop showed significantly higher survival rate than that with EM grid (67.7% vs. 53.5%, p<0.05). On the other hand, proportion of normal spindle and chromosome configurations of the frozen-thawed oocytes between two vitrification group was not significantly different. Conclusion: For mouse ovulated oocytes, vitrification with cryo loop may be a preferable procedure compared to slow-freezing method. Further study should be needed to investigate developmental competency of frozen-thawed mouse oocytes.

달 궤도 진입 목표값 변화에 따른 궤도요소 변화 연구

최수진,김인규,문상만,민승용,류동영,Choi, Su-Jin,Kim, In-Kyu,Moon, Sang-Man,Min, SeungYong,Rew, Dong-Young 항공우주시스템공학회 2015 항공우주시스템공학회지 Vol.9 No.4

Korea Aerospace Research Institute(here after KARI) has a plan to launch experimental lunar orbiter in 2018, and lunar orbiter and lander in 2020. There are several ways to go to the moon. Which one is direct transfer trajectory and another one is phasing loop transfer trajectory and the other one is WSB trajectory. Regardless of the transfer trajectories, LOI maneuver is the most important maneuver of all mission sequences because if this burn is failed, it is too difficult to get into the lunar orbit in the future. This paper describes first LOI target value of foreign lunar orbiters and analyzes orbital variations of experimental lunar orbiter according to various target values. By analyzing the variation of orbiter parameter after first LOI, proper orbital period for LOI target value are recommended to meet the inclination, apoapsis and periapsis altitude constraints.

Efficacy of Frozen-Thawed ET in Patients with Old Age or Non-Pregnant in Fresh ET Cycles

최수진,이선희,송인옥,궁미경,강인수,전진현,Choi, Su Jin,Lee, Sun Hee,Song, In Ok,Koong, Mi Kyoung,Kang, Inn Soo,Jun, Jin Hyun The Korean Society for Reproductive Medicine 2006 Clinical and Experimental Reproductive Medicine Vol.33 No.4

목 적: 동결-융해 배아이식은 보조생식술에서 환자들에게 보다 많은 임신의 기회를 제공해줄 수 있는 방법으로 이용되고 있다. 본 연구에서는 예후가 좋지 않은 환자들에서 동결-융해 배아이식의 효용성을 알아보고자 하였다. 연구방법: 나이가 많은 고령 환자군 (38~44세)과 신선주기 배아이식에서 임신 실패군을 연구대상으로 하였다. 과배란 유도를 통해 채취한 난자를 일반적인 체외수정 또는 세포질내 정자주입술을 시행하여 수정을 유도하고, 잉여의 전핵 또는 난할 시기의 배아를 완만동결법으로 동결하였다. 동결보관 배아는 급속융해법으로 융해하여 호르몬요법을 시행한 환자의 자궁에 이식하였다. 신선 배아이식과 동결-융해 배아이식 과정에서의 배아 상태, 임신율, 착상률 등을 통계적인 방법으로 분석하였다. 결 과: 나이가 많은 고령군에서 신선 배아이식을 시행한 환자들과 동결-융해 배아이식을 시행한 환자들의 평균 연령은 $40.0{\pm}1.8$세 (n=206)와 $39.9{\pm}1.9$세 (n=69)로 통계적으로 유의한 차이가 없었으나, 임상적인 임신율과 착상률은 동결-융해 배아이식에서 29.0%와 11.2%로 신선 배아이식의 16.5%와 7.0%에 비해 통계적으로 유의하게 높게 나타났다. (p<0.05). 첫 번째 신선 배아이식에서 임신 실패군의 연속되는 신선 배아이식 환자군 ($31.2{\pm}2.3$, n=40)과 동결-융해 배아이식 환자군 ($31.9{\pm}3.1$, n=119)에서의 평균 연령은 차이가 없었으며, 임상적 임신율 (42.5% vs 40.3%)과 착상률 (22.6% vs 18.8%)도 유사하였다. 결 론: 본 연구에서는 동결-융해 배아이식이 고령 환자들에서 효과적으로 임신율과 착상률을 높일 수 있음을 보여주고 있다. 이러한 결과는 과배란 유도에 따른 자궁의 착상 환경 변화가 고령 환자들에서 임신율과 착상률을 저하시키는 것과 관련이 있을 것으로 생각된다. Objective: The aim of this study was to evaluate the efficacy of frozen-thawed ET in poor prognosis patients such as the old age (38~44 years; OA group) and the patients who did not achieve clinical pregnancy with the first fresh ET cycle (non-pregnant patients; NP group). Methods: Laboratory and clinical data were collected from fresh and frozen-thawed ET cycles of OA and NP group. Controlled ovarian hyperstimulation (COH) and conventional insemination or ICSI, in vitro culture and ET were performed by routine procedures. Supernumerary embryos were frozen by the slow freezing method, and frozen embryos were thawed by the rapid thawing method. Embryo development, pregnancy and implantation rates were statistically analyzed by Student t-test and chi square test Results: Mean ages were similar between fresh ET ($40.0{\pm}1.8$ years, n=206) and frozen-thawed ET ($39.9{\pm}1.9$ years, n=69) cycles in OA group. However, the clinical pregnancy and implantation rate of subsequent frozen-thawed ET significantly higher than those of fresh ET cycles (29.0% and 11.2% vs. 16.5% and 7.0%, p<0.05). In NP group, there was no difference in the mean age between fresh ET ($31.2{\pm}2.3$ years, n=40) and frozen-thawed ET ($31.9{\pm}3.1$ years, n=119) in subsequent cycles. The clinical pregnancy and implantation rates were similar between the subsequent fresh ET (42.5% and 22.6%) and the frozen-thawed ET (40.3% and 18.8%). Conclusion: In old age patients, higher pregnancy rate of frozen-thawed ET compared to fresh ET cycles in this study. It may be related that better uterine environments for implantation in frozen-thawed ET cycles than that of non-physiological hormonal condition in uterus of fresh COH cycles.

반복 읽기에서 음소 지도가 초등학생의 영어 읽기 유창성에 미치는 효과

최수진,이윤,Choi. Soo-Jin,Lee. Yoon 한국영어교과교육학회 2015 영어교과교육 Vol.14 No.1

The purpose of the current study is to explore the effects of phonemic awareness instruction along with repeated reading on elementary school students’ English reading fluency. For this study, 108 fifth grade elementary school students were selected and divided into two groups: While group A was instructed by repeated reading along with the phonemic awareness activities, group B was taught only by repeated reading for twelve weeks. After the experiment, a post-test was carried out to assess their word recognition, reading rate, prosody, and comprehension skills. A t-test was utilized to make a statistical analysis of the collected data. The analyzed data showed the following results: Both groups showed significant progress on reading accuracy, reading rate, prosody, and comprehension. However, the group taught by phonemic awareness activities and repeated reading performed better than the group taught only by repeated reading on reading accuracy and prosody. On the basis of the analysis, it could be concluded that phonemic awareness activities led to increased reading accuracy, prosody and comprehension. Given the findings of the study, some ideas for enhancing reading fluency were suggested.

배양액 내의 마그네슘 이온이 생쥐 초기 배아 발생에 미치는 영향

최수진,전진현,박용석,배인하,Choi, Soo-Jin,Jun, Jin-Hyun,Park, Yong-Seog,Bae, In-Ha 대한생식의학회 2001 Clinical and Experimental Reproductive Medicine Vol.28 No.3

Objective: The present study was undertaken to examine the effects of magnesium ion in the culture medium on the development of mouse fertilized oocytes either before or after pronuclear formation, and to investigate whether the effect of magnesium ion is related with the redistributional change of mitochondria. Methods : Fertilized oocytes obtained from the oviducts of mice at 15 hr after hCG injection before pronuclear formation (pre-PN) or 21 hr after hCG injection after pronuclear formation (post-PN) were used. The embryos were cultured for 3 days with basic T6 medium-magnesium free and various concentrations of magnesium ion, 0.0, 0.5, 1.0, 2.0, 4.0 or 8.0 mM, respectively. After culture, the developmental stages of embryos and the number of nuclei were evaluated. To observe the effects of magnesium ion on the mitochondrial distribution, fertilized oocytes were collected at 21 hr after hCG injection and cultured for 6 hr with various concentration of magnesium ion. As a control, fertilized oocytes with pronuclei at 27 hr after hCG injection were used. Results: The concentration of magnesium ion to accelerate the in vitro development of mouse fertilized oocytes appeared to be at 2.0 mM for the pre-PN and the post-PN stage embryos. In the mitochondrial redistribution patterns, the embryos cultured in 2.0 mM concentration of magnesium ion showed the highest percentage (22.6%) of distinct perinuclear clustering pattern comparing to other experimental group. Conclusion: The effect of magnesium ion may be related to the cytoplasmic redistribution of mitochondria. This relationship seems to connect the developmental competence of preimplantation mouse embryos in vitro. These results can suggest that higher concentration of magnesium ion (2.0 mM) than those of conventional culture medium ($0.2{\sim}1.2\;mM$) is more suitable for in vitro culture of preimplantation mouse embryos.

카이랄 망간(III)-살렌 착화합물을 촉매로 이용한 설파이드의 비대칭 설폭시화 반응

최수진,안광현,Choi, Soo-Jin,Ahn, Kwang-Hyun 대한화학회 2008 대한화학회지 Vol.52 No.6