한국 성인 여성의 손 계측연구 : 장갑의 치수 설정을 중심으로 Focusing on Glove Size

류경옥,서미아 服飾文化學會 2004 服飾文化硏究 Vol.12 No.2

The purpose of this study was to develop the sizing system for women's glove. The combination of anthropometric and engineering aspects of glove pattern-making is difficult problem in engineering clothing. And the traditional measurements is not enough for glove. Therefore, to develop the hand measurement method and dimension for glove, a comprehensive list of candidate measurements was reviewed and the manufacturers (Their career was over the 15years.) were interviewed on the method of glove pattern-making. This study was conducted traditional and creative 88 two-dimensional anthropometric measurements and 4 photometric measurements for glove pattern-making. In addition, 16 creative measurements were instrumented using a special hand measuring board for measuring of landmark locations on the hand. The subjects were 260 women's right hand in the age group of 18 to 35 years old in Korea.

청소년의 컴퓨터게임 이용실태, 부모양육방식, 개인의 정신병리

전성일,류정환,김영미,정홍경,조아라,이정호,최영민,이기철 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.1

연구목적 : 오늘날 컴퓨터게임은 청소년기의 보편적 놀이도구가 된 상황임에도 불구하고 이들이 게임에 몰두하는 이유와 개인특성에 관한 정신과적 연구는 드문 실정이다. 이러한 필요성에서 본 연구는 중학교 2년 생을 대상으로 청소년의 컴퓨터게임 사용실태를 파악하고, 연관된 개인정신병리와 부모의 양육방식과의 관계를 밝히고자 하였다. 방법 : 이 연구는 서울시 노원구에 위치한 중학 2년생 124명을 대상으로 하였다. 정신병리의 측정을 위하여 한국판 간이정신진단검사(SCL-90-R)을 사용하였고, 부모자녀 결합형태 조사(PBI)를 통하여 부모양육태도를 알아보았다. 결과 : 1) 비록 과도한 시간을 들여 컴퓨터게임을 하더라도, 컴퓨터게임과 연관된 특정 정신병리는 발견할 수 없었으며 따라서 콤퓨터게임은 청소년기에 있을 수 있는 일상적인 놀이문화이다. 또 한대 부분의 청소년은 컴퓨터게임이 문제가 되지 않는다고 인신하고 있었다. 2) 남학생은 게임빈도, 게임시간, 게임방에서 보내는 시간, 게임을 한 번 할 때 지속하는 시간 등에서 여학생에 비해 통계적으로 의미 있게 높은 수치를 보였다. 3) 청소년의 신체증상호소, 타인간의 관계에서 나타나는 불편감, 우울증, 불안증의 정신병리는 컴퓨터 오락으로 인한 부작용과 의미 있는 관계를 보였다. 4) 게임빈도와 FBI상의 어머니 과보호척도는 정적인 상관관계를 보였다. 5) 게임을 하는 이유로는 공부, 학교 생활 등의 복잡한 것을 잊고 몰두하기 위해가 가장 많았고, 가장 심리적으로 부담이 되어 피하고 싶은 것으로는 학업문제였다. 6) 청소년은 게임방을 주로 친구들과 어울리는 공간으로 사용하고 있었지만 그 기능을 다하기에는 아직 보완해야 할 점이 많다. 결론 : 게임으로 인한 부모, 교사와의 다툼, 잦은 지각/결석, 친구들과 어울리지 못하는 등의 문제가 많은 경우에는 청소년 자체의 정신별리를 의심해 보아야 하며, 게임의 빈도가 의미 있게 높은 청소년의 경우에는 둥반되는 정서상의 문제와 함께 부모양육태도도 함께 세심하게 살피는 것이 필요하다. Objects : This study was designed or studying of current Korean adolescents computer game playing habits and exploring associations with parental rearing patterns and individual psychopathology. Methods : One hundred twenty our adolescents(age 13-15) who reside in urban area completed self-report questionnaires containing Questionnaires designed by authors, Symptom Checklist-90-Revision of Korean Version(SCL-90-R) and Parental Bonding Instrument(PBI). Results : 1)Computer game playing appears to be one of the social and leisure phenomena in these days. Although Adolescents spend a lot of times on computer game, Many of them perceive not problematic. 2)Compared with females, Male play computer games more regularly, more longer, spent more times in gamebang. 3)There was positive relationship between anxiety subscale in SCL-90-R and detrimental effects of computer game. 4)There was positive relationship between game frequency and maternal overprotection. 5)The main reasons for playing are "for an avoidance of stressful life events" , academic burden was the most troublesome issues in korean adolescents. 6)Many adolescents use gamebang as a social place, but they thought that gamebang is not good places to have a good time. Conclusion : This papers shows that computer game playing is a popular social leisure activity in Korean adolescents. And, Most of korean adolescents reported that they are suffered from pressure of academic achievements. They use computer game mainly by means of relieving academic pressures. In a heavy game users who have many conflicts with parents, teacher and who has frequent truancy and social withdrawal show significant anxiety. Maternal overprotection was observed in heavy game users. Authors recommended that clinicians should be careful in examining heavy computer game behaviors. Both underlying affective states and environmental influences, including family situations should be vicariously examined. KEY WORDS : Computer game · Gamebang · Game habits · Psychopathology · Parental rearing pattern.

Expression and purification of biologically active human FGF2 containing the b'a' domains of human PDI in Escherichia coli.

Song, Jung-A,Koo, Bon-Kyung,Chong, Seon Ha,Kwak, Jihye,Ryu, Han-Bong,Nguyen, Minh Tan,Vu, Thu Trang Thi,Jeong, Boram,Kim, Seong Who,Choe, Han Humana Press 2013 Applied biochemistry and biotechnology Vol.170 No.1

<P>Among the members of the fibroblast growth factor (FGF) family that affect the growth, differentiation, migration, and survival of many cell types, FGF2 is the most abundant in the central nervous system. Because of its wound healing effects, FGF2 has potential as a therapeutic agent. The protein is also added to the culture media to maintain stem cells. Expression and purification procedures for FGF2 that are highly efficient and low cost have been intensively investigated for the past two decades. Our current study focuses on the purification of FGF2 fused with b'a' domains of human protein disulfide isomerase to elevate overexpression, solubility, and stability with a simplified experimental procedure using only ion exchange chromatography, as well as on the confirmation of the biological activity of FGF2 on fibroblast Balb/c 3T3 cells and hippocampal neural cells.</P>

양악전돌증 환자에서 하악 6전치 후방 이동 시 치료 방법에 따른 하악 경조직과 연조직의 변화: 하악 전방분절골절단술과 발치 교정 치료

김영주,김경아,유용재,유경선,유정민,오주영,김수정,김성훈,이백수,Kim, Young-Joo,Kim, Kyung-A,Yu, Yong-Jae,Ryu, Kyung-Sun,Ryu, Jeong-Min,Ohe, Joo-Young,Kim, Su-Jung,Kim, Seoung-Hun,Lee, Baek-Soo 대한악안면성형재건외과학회 2012 Maxillofacial Plastic Reconstructive Surgery Vol.34 No.4

Purpose: The purpose of the study is to evaluate the effectiveness of anterior segmental osteotomy (ASO) in bimaxillary protrusion (BP) patients by comparison between the mandibular soft and hard tissue changes from orthodontic treatment and ASO. Methods: All 44 patients were diagnosed with BP in Kyung-Hee Medical Center. Orthodontic treatment with teeth extractions were underwent by 23 patients (Group A) and 21 patients underwent ASO (Group B). Mandibular soft and hard tissue changes were measured and evaluated, which were based on the vertical and horizontal reference line in lateral cephalometric radiographs. Statistical significance between the changes and correlation between each measurement were analyzed. Results: The amount of B point movement was lesser than that of the lower incisal tip (LIT) retraction, and LIT was tilted lingually in group A. The posterior movement discrepancy between LIT and B point was insignificant, and the inclination of lower incisor was not changed in group B. The soft tissues, including the lower lip, showed a posterior movement and reduction in the depth of mento-labial groove. According to the correlation analysis, the movement of the lower incisor was significantly related to the movement of the lower lip in group A, and the movement of the lower incisor was significantly related to that of the movement of lower lip, B point and Pog in group B. Conclusion: The orthodontic treatment in BP patients results in posterior tilting movement of the lower incisor, but ASO results in the bodily movement of the lower incisor. Consequently, ASO is more effective in BP cases because it ensures the controlled movement of the lower incisors.

조직배양 감자의 플러그육묘재배에 있어서 식물재료가 지하괴경 형성에 미치는 영향

이현숙(Hyun Suk Lee),정재동(Jae Dong Chung),류정아(Iung A Ryu1),황형백(Huyng Baek Hwang),최경배(Kyung Bae Choi) 한국원예학회 2002 한국원예학회 학술발표요지 Vol.2002 No.3

온백원이 암세포에 미치는 항암활성 효과

이지영,오혜경,류한성,김남재,정원용,오현아,최혁재,윤성우,류봉하,Lee, Jee Young,Oh, Hye Kyung,Ryu, Han Sung,Kim, Nam Jae,Jung, Won-Yong,Oh, Hyun-A,Choi, Hyuck Jai,Yoon, Seong Woo,Ryu, Bong-Ha 대한암한의학회 2015 大韓癌韓醫學會誌 Vol.20 No.2

Objective : The objective of this study was to investigate the experimental efficacy of anti-tumor activity of the complexed herbal formula, Onbaekwon (OBW), which was derived from the literature of Traditional Korean Medicine, Dongeuibogam. Methods : Nine Cancer cell lines, LoVo, MCF-7, HepG2, AGS, A549, NCI-H69, HL-60, Sarcoma 180, LL/2, were prepared and the cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2yl)-2,5-dephenyl tetrazolium bromide (MTT) assay. Four of them, NCI-H69, HL-60, Sarcoma 180, and LL/2, showed strong cytotoxic activities and they were additionally undergone flow cytometry to find out their effects on apoptosis. ICR male mice were implanted with Sarcoma 180 intraperitoneally and divided into 8 species for each group. Control group was treated with normal saline, positive control group was treated with cyclophosphamide 8mg/kg, and experimental group was treated with OBW 1 g/kg. Results : Among 9 cancer cell lines, NCI-H69, HL-60, Sarcoma 180, and LL/2, expressed less than 0.10 mg/ml of $IC_{50}$ under 0.1~1mg/ml of OBW. NCI-H69, HL-60, Sarcoma 180, and LL/2, showed dose-dependent efficacy of apoptosis. When Sarcoma 180 cancer cell was implanted in ICR male mice and treated with the OBW, they prolonged the median overall survival for 0.8 days, from 17.5 to 18.3. Conclusion : OBW showed strong cytotoxicity to some cancer cells, which are NCI-H69, HL-60, Sarcoma 180, and LL/2, and its apoptotic activity was dose-dependent. OBW prolonged the median survival of mice implanted with Sarcoma 180. Further researches would be expected to support the efficacy of OBW.

CRISPR/Cas9-mediated genome editing of splicing mutation causing congenital hearing loss

Ryu, Nari,Kim, Min-A,Choi, Deok-Gyun,Kim, Ye-Ri,Sonn, Jong Kyung,Lee, Kyu-Yup,Kim, Un-Kyung Elsevier 2019 Gene Vol.703 No.-

<P><B>Abstract</B></P> <P>Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has ushered in a new era of gene therapy. In this study, we aimed to demonstrate precise CRISPR/Cas9-mediated genome editing of the splicing mutation c.919-2A > G in intron 7 of the <I>SLC26A4</I> gene, which is the second most common causative gene of congenital hearing loss. We designed candidate single-guide RNAs (sgRNAs) aimed to direct the targeting of <I>Staphylococcus aureus</I> Cas9 to either exon 7 or exon 8 of <I>SLC26A4</I>. Several of the designed sgRNAs showed targeting activity, with average indel efficiencies ranging from approximately 14% to 25%. The usage of dual sgRNAs delivered both into Neuro2a cells and primary mouse embryonic fibroblasts resulted in the successful removal of large genomic fragments within the target locus. We subsequently evaluated genome editing in the presence of artificial donor templates to induce precise target modification <I>via</I> homology-directed repair. Using this approach, two different donor plasmids successfully introduced silent mutations within the c.919-2A region of <I>Slc26a4</I> without evident off-target activities. Overall, these results indicate that CRISPR/Cas9-mediated correction of mutations in the <I>Slc26a4</I> gene is a feasible therapeutic option for restoration of hearing loss.</P> <P><B>Highlights</B></P> <P> <UL> <LI> SaCas9 and designed sgRNAs were evaluated to modify c.919-2A within <I>Slc26a4</I>. </LI> <LI> Applying 2 sgRNAs <I>in vitro</I> showed removal of genomic DNA within the target locus. </LI> <LI> <I>Ex vivo</I> viral infection of sgRNAs and donor template precisely edited the target. </LI> </UL> </P>

Relationship between ganglioside expression and anticancer effects of a plant-derived monoclonal antibody against epithelial cell adhesion molecule in colon cancer

Jae-Sung Ryu,Mi-Ran Hwang,Ju-Taek Lee,Malg-Um Lim,Yoon-Ju Na,Su-Bin Lee,Jeong-Hwan Lee,Kisung Ko,Kyung-A Hwang,Young-Kug Choo 한국당과학회 2012 한국당과학회 학술대회 Vol.2012 No.1

The human colorectal carcinoma-associated GA733 antigen is an epithelial cell adhesion molecule (EpCAM), initially described as a cell surface protein selectively expressed in some myeloid cancers. We demonstrated that treatment with plant-derived anti-EpCAM mAb (mAbp CO17-1A) and RAW264.7 cells significantly inhibited cell growth in SW620 cells. Expression of p53 and p21 increased, whereas the expression of G1 phase-related proteins, cyclin D1, CDK4, cyclin E, and CDK, decreased. In addition, mAbp CO17-1A and RAW264.7 cell treatment decreased the expression of anti-apoptotic proteins such as Bcl-2, but the expression of pro-apoptotic proteins Bax, TNF-α, caspase-8, caspase-9, caspase-3 and caspase-6 increased. HPTLC analysis showed that the cells treated with mAbp CO17-1A and RAW264.7 cells newly expresses GM1 and GD1a. These results suggest that mAbp CO17-1A could have an anticancer effect. Further clinical investigation should be conducted on mAbp CO17-1A to determine its possible chemopreventive and/or therapeutic efficacy for the treatment of human colon cancer.

A Study on the Measurement of Male Korean Hand - Focusing on Glove Size -

Ryu, Kyung-ok,Suh, Mi-a The Costume Culture Association 2003 Fashion, industry and education Vol.6 No.2

The purpose of this study was to develop the sizing system for men's glove. The combination of anthropometric and engineering aspects of glove pattern-making is difficult problem in engineering clothing. And the traditional measurements is not enough for glove. Therefore, to develop the hand measurement method and dimension for glove, a comprehensive list of candidate measurements was reviewed and the manufacturers (Their career was over the 15years) were interviewed on the method of glove pattern-making. This study was conducted traditional and creative 88 two-dimensional anthropometric measurements and 4 photometric measurements for glove pattern-making. In addition, 16 creative measurements were instrumented using a special hand measuring board for measuring of landmark locations on the hand. The subjects were 260 men's right hand in the age group of 18 to 35 years old in korea.

일부지역 대학생의 구강보건지식과 구강건강인식에 대한 조사

윤현서(Hyun-Seo Yoon),남유영(You-Young Nam),유현아( Hyun-A Ryu),김혜진(Hye-Jin Kim),이민경(Min-Kyung Lee),이정화(Jung-Hwa Lee) 한국구강보건과학회 2013 한국구강보건과학회지 Vol.1 No.1

The purpose of this study was to survey the oral health knowledge and the oral health perception of university students in some districts. It divided it into by department for one month in March of 2013, surveyed totally 310 people, and then finally analyzed 302 people. The results are as follows. In the oral health care knowledge, a percentage of correct answers as saying of needing to receive regular check-up once per 6 months was the highest with 97.7%. A percentage of correct answers as saying that food of containing lots of sugar is good for health of teeth was the lowest with 10.9%. The oral health knowledge according to general characteristics was high in women(p=0.036). The age was the highest in 21-22 years old and was the lowest in 25-27 years old(p=0.001). In department, the health department was indicated to be the highest. The natural-science department was indicated to be low, thereby having shown difference(p<0.001). In academic year, sophomore was the highest. Senior was indicated to be the lowest(p=0.030). A case of non-smoking was high in knowledge level(p=0.027). A case of not having part-time job was indicated to be high in knowledge level(p=0.032). A case of recognizing that the whole health status is very healthy was low in oral health perception level(p<0.001). The more perception as saying that the oral health status is very healthy led to the lower even in the oral health perception level(p<0.001). To improve the oral health of college students develop a systematic curriculum and teaching methods are needed for the distressed people.