부산지역 무균성 뇌막염 원인 바이러스의 분리 및 동정 : 1998년을 중심으로

김영희,정영기,김기순,지영미,윤재득,김병준,구평태,민상기,정구영,김만수,조경순 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

The incidence of aseptic meningitis infection is ensuing and threatening the health of children. Enteroviruses are the major agents of aseptic meningitis and identification of virus has been a clue to diagnosis and epidemiology. The outbreak of aseptic meningitis occurred in Pusan, 1998. Patients were concentrated from April through November. Children were more susceptible than adults. Among 306 cases of specimens from stool, throat swab tested, only 7.2% were positive on virus isolation, 12 cases from stool and 10 from throat, respectively. All isolated 7 serotypes of viruses represented cytopathic effect on cultured cells. Three types of echovirus 6, 25, 30 and coxsackievirus B2, B3, B4, B6 were identified by neutralizing anti body test. Isolated coxsackievirus and echovirus were observed by an electron microscope with negative staining.

다발성 대장암 간전이 환자의 간절제를 위한 새로운 시도

주종우,김형철,임철완,신응진,조규석,유기원,송옥평,홍대식,박성진,조준희,이혜경,김희경,권계원,고은석 순천향의학연구소;Soonchunhyang Medical Research Institute 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Multiple bilobar liver matastases (MBLM) are the main cause of low resectability in the colon cancer liver metastases. The authors experienced one case of initially non-resectable colon cancer liver metastases. He was curatively and safely treated with a two-stage hepatectomy using the new method of future remnant liver volume growing. A 54-year-old man was referred to our department with the sigmoid colon cancer combined with MBLM, which were checked in two small metastatic lesions in the left lobe and five large sized lesions in the right lobe in the computed tomogram (CT). A laparoscopic assisted anterior resection was primarily performed. We performed the 1^(st) stage hepatectomy 3 weeks after the colon resection. Intra-operative Ultrasonogram (US) found 9 small superficial metastatic lesions in the left lobe. All that lesions were completely removed by non-anatomical wedge resection. An occlusion ballon catheter was placed in the right portal vein through a small branch of the inferior mesenteric vein at that time. The future remnant liver volume was sufficiently increased 3 weeks after the 1^(st) hepatectomy. A right hepatectomy was safely performed 22 days after the 1^(st) hepatectomy. The patient received a regional chemotherapy (interleukin2 based immuno-chemotherapy through hepatic artery) for 4 months, then received 9 cycles of systemic chemotherapy (biweekly Oxaliplation, leucovorin, plus 5-fluorouracil) without any recurrence evidence.

Mirizzi 증후군의 변형된 분류와 치료

김형철,강길호,채만규,김성용,백무준,이문수,박상흠,이문호,김창호,송옥평,조무식,박희주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Purpose : The Mirizzi syndrome is relatively rare and preoperative diagnosis of this disease is difficult. In 1978, Morelli suggested the subclassification of the Mirizzi syndrome into acute or chronic form. We experienced 5 cases of acute form. We analysed clinical features, preoperative radiologic findings and operative findings of 18 cases including acute forms which were diagnosed as Mirizzi syndrome and should suggest the modified classification of Mirizzi syndrome for choice of appropriate treatment. Method : From January 1995 to December 1998, 18 cases, of which 8 cases were diagnosed at Soonchunhyang University Chunan Hospital, and 10 cases were reported in the Korean Journal were retrospectively analysed with regard to clinical features, preoperative radiologic findings and operative findings. According to the clinical features, whole cases were divided into type Ⅰ(acute form) and type Ⅱ(chronic form) and then each type of cases were subclassified according to preoperative radiologic findings and operative findings. Results : Of 18 cases there were 5 cases in type Ⅰ(27.8%), 13 cases in type Ⅱ(72.2%). Type Ⅱb was most common. Type Ⅰa cases were treated only with cholecystectomy. We applied cholecystectomy, T-tube choledochostomy and patch technique in type Ⅰb and thpe Ⅰc cases. Cholectystectomies including removal of gallstones and internal drainage procedures were done in type Ⅱ chronic forms. Conclusion : The acute form(Type Ⅰ) of Mirizzi syndrome was suggested by Morelli might be subclassified into typeⅠa,Ⅰb and Ⅰc following the presence of the necrotic defect in common hepatic duct. Through the modified classification of Mirizzi syndrome based on clinical feature, preoperative radiologic findings and operative findings, we can choice appropriate treatment.

광섬유 Mach-Zehnder 간섭계 센서를 사용한 압력과 스트레인 측정

김태희,은재정,최평석 國立 昌原大學校 産業技術硏究所 1995 産技硏論文集 Vol.9 No.-

A fiber optic Mach-Zehnder interferometric sensor to measure both pressure and strain is analyzed utilizing the pressure- and strain-induced phase shift in coherent light wave propagating through an single-mode optical fiber. And then the Mach-Zehnder interferometer is experimentally implemented to confirm the analysis. For the dynamic case, the average values measured with respect to pressure ad strain sensitivities of one fringe displacement are 67.762 kPa and 1.111-6. For the quasi-static case, the values measured for one fringe displacement are 16.941 kPa and 0.2778?10-6. Taking into account the experimental uncertainty due to the drift in interference fringe position owing mainly to the environmental lower frequency noise and the differences between the exact parameter values for fibers used in the experiments and the typical values of a fused silica fibers, the results obtained by the experiments are in good agreement with those calculated.

교육공학의 연구에 대한 고찰 및 분석 : 1960년~1983년

김인경,신은주,이평희,정인영 이화여자대학교 사범대학 시청각교육과 1983 시청각 교육 Vol.- No.13

산재지정병원 이용 후 산재요양환자에 대한 만족도 조사

이화평,임형준,주영수,권영준,강희태,김정민,조성식,이태경,윤종완 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.3

새로운 구조의 fiber Fabry-Perot filter를 사용한 파장가변 단일방향 EDF ring 레이저

이희철,조성진,김용평,예윤해 경희대학교 레이저공학연구소 2001 레이저공학 Vol.12 No.-

We made the tunable unidirectional Er-doped fiber(EDF) ring laser by using new fiber Fabry-Perot(FP) filter. Filter has been built with simple construction, with does not require any additional aligning and beam-confining components for the reduction of the diffraction. Fiber FP tunable filter whose free spectral range and finess is 60 nm and 500 respectively. Wavelength tunable range over 60 nm(1520-1580nm) has been achieved.

橋座裝置下의 콘크리트 破壞擧動에 관한 硏究

車熙石,金圭賢,金勇熙,姜枰求 慶南大學校 附設 工業技術硏究所 1996 硏究論文集 Vol.14 No.1

본 연구에서는 교량파손의 주원인이 되고 있는 하부구조 파손의 대부분을 차지하는 교좌부의 편심문제에 대하여 논의하였다. 교좌부는 상부구조의 지점부에 작용하는 수직하중 및 수평하중을 제한된 받침면적으로 지탱하여야 한다. 이러한 문제는 제한된 콘크리트 면적위에 매우 큰 하중이 국부적으로 작용하는 콘크리트의 지압강도 문제로 귀착되는데 그 거동은 단순치 않다. 따라서 실제 문제에서는 교좌부의 형태가 圓形 또는 矩形이 일반적이나 기초적 연구로서 교좌부의 위치가 교축방향에 직각방향으로 변화할 때 입방공시체의 편심에 따른 파괴거동을 규명하였다. 가압판은 모델의 편의성에 의해 대상하중을 사용하였으며, 편심하중의 위치결정에 근거를 제시하고자 각 절점의 변위 및 요소의 응력상태를 수치해석하여 얻으므로서 교좌부의 파괴거동을 명확히 알 수 있었다. This study examined an eccentricity effect on a shoe of bridge. Bridge fracture occurs on its super-structure and sub-structure. The sub-structure fracture generally results from an eccentricity on the shoe. A shoe with a limited area must withhold all vertical and horizontal loads applied from a bridge super-structure. This mean a problem of concrete bearing capacity, in which a relatively large amount of load is applied on a small area of concrete. A bridge shoe generally has a circular or rectangular shape, but a cube specimen was used in this study to examine the fracture behavior of the shoe by the eccentricity. For this porpose, the shoe location was varied vertically to a bridge axis. In order to understand the fracture behavior with more dedail, each node's displacement and each element's stress was calculated using numerical analysis.

이종 장기 이식을 위한 다단계 거부 반응의 조절

이광수,김영관,박희진,이재오,명평근 忠南大學校 生命科學硏究院 醫藥品開發硏究所 2006 藥學論文集 Vol.21 No.-

The transplantation of organ, tissues or cells between individuals of different species has been of increasing interest in recent years because the use of animals as organ and tissue donors as a source of transplants would overcome the severe and worsening shortage of human organs available for transplantation. However, There are some major hurdles to the clinical application of xenotransplantation; the immunologic response of the recipient against donor, the physiology of the graft, and the possibility that a xenotransplant might transmit an infection from the source to the recipient. This review describes the unique aspects of the immunological barrier to transplanting organs from non-primates such as pigs into humans, focusing especially on the mechanisms which contribute to immunorecognition, physiology of the rejection and infectious hurdles to xenotransplantation. This communication might be applied to overcoming these hurdles and the possibility that genetic strategies might be used to expand the potential applications of xenotransplantation for the treatment of human disease.

동결 보존에 의한 돼지 정자 세포질 칼슘 신호의 변화

이선우,이옥화,김준철,명평근,박창식,우선희 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

Although mammalian sperms are cryopreserved for in vitro fertilization a process of cryopreservation decreases the fertility. Acrosome reaction requires depolarization-induced ca^(2+) influx and ca^(2+) releases from the ca^(2+) stores. To examine whether the cellular ca^(2+) mobilization is altered by a sperm cryopreservation we compared cytosolic ca^(2+) signals between fresh and cryopreserved pig sperms using confocal ca^(2+) imaging. The magnitudes of depolarization-induced ca^(2+) increases were significantly smaller in cryopreserved sperms. Exposures to 10 mM caffeine or 5 μM thapsigargin elicited less ca^(2+) increases in the cryopreserved sperms compared to fresh sperms. In addition, progesterone-triggered ca^(2+) rises, that are thought to enhance acrosome reaction, were completely abolished in the cryopreserved sperms. These results suggest that storage and(/or) release of ca^(2+) from the intracellular ca^(2+) stores in pig sperms are significantly impaired by the process of cryopreservation.