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이순복,조태순,윤기욱,이종찬,이선미,심성보 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1
The dose-response effect of polysaccharide extracts(PS-1) from Artemisia iwayomogi was investigated under various hepatic disease models. Silymarin, DDB and UDCA were used as reference compounds. We found that the maximal effective dose of PS-1 was 100 ㎎/㎏ b.wt. in CCl_4-induced hepatotoxicity, D-galactosamine-induced hepatitis, in ANIT-induced cholestasis and 300 ㎎/㎏ b.wt. in CCl_4-induced chronic liver disease, 30 ㎎/㎏ b.wt. in chronic bile duct ligation and chronic ethanol fatty liver. These findings suggest that PS-1 fraction protects the hepatocyte against various hepatic injuries, and this fracton might be of therapeutic value.
열탈착 분석법에 의한 Pt(111) 표면위의 NO와 CO의 흡착
이순보,박종윤,곽현태,부진효,강용철 성균관대학교 1992 論文集 Vol.42 No.2
The adsorptions of nitric oxide and carbon monoxide on Pt(111) surfaces have been studied by using LEED, AES, and TDS(Thermal Desorption spectroscopy). The adsorbed species of NO is predominantly molecular on the Pt(111) surface at room temperature. A main desorption peak of TDS is attributed to the molecular adsorption at 360K. With increasing No exposures, a shoulder peak at 480K which may be attributed to the defect site adsorption is appeared. The desorption rate order for No desorption is 1st order and the desorption energy for NO calculated by Redhead equation assuming pre-exponential factor v_1=10^13 sec^-1 is 21.7Kcal/mol. The adsorption of carbon monoxide is also molecular on Pt(111) surface at room temperature. The TDS results showed only a single broad peak at 460K, which is attributed to molecular adsorption. The desorption order for CO desorption is 1st order as well as NO and the desorption energy for CO is 28Kcal/mol.
Ar 이온에 의해 Sputtering된 Pt(111) 표면의 NO 흡착
이순보,부진효,이성용,박종윤,곽현태 성균관대학교 기초과학연구소 1992 論文集 Vol.43 No.1
Adsorption of nitric oxide on the Pt(111) surface sputtered by Ar-ion has been studied using thermal desorption spectroscopy, Auger electron spectroscopy, and low energy electron diffraction. A thermal desorption spectrum obtained from the perfect Pt(111) saturated with NO at 300K is quite simillar to those reported previously. The main portion desorbs at about 370K(α-state) with a shoulder at about 470K(β-state). The chemisorption of nitric oxide is predominantly molecular on the Pt(111) surface, accompanied by a small amount of dissociation which becomes negligible when the Pt(111) surface is perfect. When the Pt(111) surface is sputtered by Ar-ion with 2KeV, the thermal desorption spectrum becomes quite complex. The shoulder peak, which appears on the perfect surface spectrum, increases with Ar-ion sputtering time. The maximum desorption spectra of N₂ and N₂O are observed simultaneously between 470 and 600K. The desorption mechanisms for N₂O are proposed. The increasing N₂ with the β-state of NO indicates that the β-state is a precursor to the NO dissociation.
이보선,박순호,이필영,최정현 龍仁大學校 體育科學硏究所 2001 體育科學硏究論叢 Vol.11 No.1
The purpose of the study is to help Korean women gymnasts get better grades in the international sports arena by understanding the world trends in this field based on the analyses of performances in the parallel bars, the weakest event among the four Korean women's gymnastic events. Value, connection value by which bonus points can be obtained, and start value were analyzed, excluding demerit marks in general performances, impressions, and art. The results of the study are as follows. In the analysis of value, the top four athletes implemented more parts than the average level while the four Korean athletes achieved less than the average level. According to the analysis of value parts D and E, the top four athletes received an average of 0.675 bonus points while the Koreans got 0.15, showing a great difference among them. The analysis of connection value by which bonus points can be obtained also showed stark contrast between the top four athletes and the Koreans marking bonus points of 0.50 and 0.075, respectively. The average start value of the top four athletes was 9.95, 0.925 higher than that of the Korean athletes of 9.025, which can be considered as a big difference. It is suggested that Korean athletes should focus on conducting high level of value parts and connection value to make greater achievements in the international sports arena, considering general demerit points were not included in this study. They are also needed to be confident in order to act to the best of their abilities.
이순보,부진효,김우섭 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.2
Interactions between oxygen and carbon monoxide on Ni surface were studied by means of XPS at room temperature in UHV system attached with a. quadrupole mass spectrometer. Adsorption of CO on Ni surface precovered with oxygen are followed by three step. It was noted that CO₂ gas are formed by reaction of preadsorbed oxygen and CO molecules at initial step, and the second step is followed that precovered oxygen and CO molecules are coadsorbed, and during the high CO exposure the less pread-sorbed oxygen is, the more adsorbed CO. It could be attributed to the fact that the existence of oxygen on the Ni surface reduced the sticking coefficient of CO. Dissociative adsorption of O₂ on Ni surface were inhibited by the preadsorbed CO molecule at initial oxygen exposure. The dissociative adsorption of the preadsorbed CO increased with increasing exposures of O₂ and Ar. This was very well explained by the model of a collision-energy transfer, that a collision between the preadsorbed CO and O₂ or Ar gas cause to increase an amplitude of vibration mode contributed to dissociative adsorption so that the preadsorbed CO molecule is dissociated by the interaction of oxygen atom of adsorbed CO and Ni atoms.
고려수지요법을 이용한 손 마사지가 항암 화학요법을 받는 암 환자의 오심·구토 및 식욕부진에 미치는 효과
이현숙,성기월,손보경,김지선,이혜정,이순영 병원간호사회 2006 임상간호연구 Vol.11 No.2
Purpose: The purpose of this study was to examine the effect of hand massage through Korean hand acupuncture therapy on nausea, vomiting and anorexia induced by chemotherapy in cancer patients. Method: Subjects consisted of 40 patients with cancer who were hospitalized and had chemotherapy at D university hospital in D city, Korea. These subject were assigned randomly to a hand massage throght Korean Hand Acupuncture Therapy (experimental group: n=20, control group: n=20). The data were collected from April 1 to September 15 in 2005. All the patients were assessed for their nausea, womiting and anorexia; Nausea and vomiting were measured with Rhodes INVR(index of Nausea, Vomiting by Rhodes and McDaniel) and Anorexia was measured with VAS(Visual Analogue Scale). As an experimental treatment, the hand massage through Korean Hand Acupuncture Therapy was applied three times a day for three consecutive days. The data were collected at the time of 4 hours before the start of chemotherapy, 24hours and 48hours after hand massage respectively. The data were analyzed with SPSS/WIN 11.5 program using frequency, percentage, χ²-test, t-test, repeated Measures ANOVA. Reslt: Severity of nausea and vomiting in hand massage through Korean Hand Acupuncture Therapy group was significantly less than of control group(F=28.10, P=.000). Severity of anorexia in hand massage through Korean Hand Acupuncture Therapy group was also significantly less than that of control group(F=31.24, P=.000). Conclusion: Hand massage through Korean Hand Acupuncture Therapy is effective for relieving patients' nausea, vomiting and anorexia during chemotherapy. Therefore, it is proposed that hand massage through Korean Hand Acupuncture Therapy can be applied as a supportive as a supportive nursing arbitration method to relieve naussa, vomiting and anorexia in patients who are getting chemotherapy.