사면의 안정도 해석을 위한 입체투영법

이성대,이철우,이동우,이성규 公州大學校 基礎科學硏究所 1996 自然科學硏究 Vol.5 No.-

암반 사면의 안정성을 해석하는데 입체투영기법을 이용하였다. 안정도에 영향을 미치는 요인으로는 절리의 경사, 암석의 밀도, 내부마찰각등이 있으나, 가장 중요한 요인은 절리면의 경사이다. 이 연구에서는 암석의 점착력은 무시하고 단지 내부마찰각과 절리의 주향 및 경사만을 이용하였다. 그 결과 입체투영도에서 나타나는 암반사면의 안정도는 이동력과 저항력의 상대적인 크기에 의하여 좌우되는 것으로 나타났다. 동시에, 지반진동에 의한 영향도 입체 투영기법으로 찾아낼수 있다는 것이 밝혀졌다. Stereographic projection technique was used to analyze rock slope stability. Strike and dip of joints, rock strength, and internal frictional angle are major factor on slope stability. Among them, the most important factor is strike and dip of joints. In stereographgic projection technique, only internal frictional angle, and strike and dip of joints were used to interprete slope stability. Cohesion of rock was not considered. It is suggested that the rock slope stability on stereographic projection depends upon only the differential stress between driving and resisting force. At the same time, Stereographic projection technique on seismic loading was proposed in this study.

폐암에서 CYFRA 21-1과 다른 종양표지자의 진단적 의의

이상구,이호현,전병철,김성자,이영현,김문연,하경임 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

폐암의 확실한 조직학적 진단이 어려울 경우 종양표지자의 검사가 보조적인 진단 수단이 되고, 조기 진단이나 경과 관찰에 이용되고 있다. 이에 저자는 CYFRA 21-1이 폐암의 종양표지자로서 효용성이 있는지 판정하고, CYFRA 21-1과 다른 폐암 종양표지자인 SCC Ag, CEA, NSE의 폐암의 조직학적 유형에 따른 민감도와 특이도를 비교하였다. 그리고 병기 진행에 따른 CYFRA 21-1치의 증가 여부를 관찰하고, 4가지 종양표지자를 동시에 측정하였을 때의 진단적 효용성을 비교하고자 하였다. 이 연구는 1994년 12월부터 1995년 11월까지 동국대학병원에 입원한 폐암 환자 40명과 양성 폐질환 환자 40명을 대상으로 하였다. 편평상피세포암 21명, 선암 10명, 소세포암 7명, 대세포암 2명이었다. 혈청 CYFRA 21-1의 cytokeratin 19 분절에 대한 쥐의 두 가지 단일 클론항체(KS 19-1과 BM 19-21)를 이용하는 RIA방법으로 측정하였다. CEA는 MEIA 방법으로, SCC 항원과 NSE는 RIA로 측정 하였다. 1. CYFRA 21-1의 혈중 농도는 폐암군 22.08±43.00ng/mL, 양성 폐질환군 1.14±1.04ng/mL로 폐암군에서 양성 폐질환군보다 유의하게 높았다(P<0.05). 폐암환자군에서 55%의 양성율을 보였고, SCC 항원 30%, CEA 44.7%, NSE 54.5%의 양성율을 나타내 CYFRA 21-1이 가장 높은 양성율을 보였다. 2.CYFRA 21-1은 비소세포암군 23.79±44.49ng/mL, 소세포암군 13.90±33.57ng/mL로 양군에서 유의한 차이를 보였다. 폐암환자군에서 민감도와 특이도는 CYFRA 21-1 55.0%와 96.7%, SCC항원 30.0%와 96.4%, CEA 42.5%와 92.8%, NSE 36.4%, 76.9%로 CYFRA 21-1에서 가장 높은 민감도와 특이도를 보였다. 폐암의 조직학적 유형에 따른 민감도는 편평상피세포암에서 CYFRA 21-1이 61.9%로 CYFRA 21-1의 민감도가 가장 높았고, 선암에서는 CEA가 88.8%로, 소세포암에서는 NSE가 85.7%로 가장 민감도가 높은 것으로 나타났다. 3. 비소세포암군에서 CYFRA 21-1치는 병기가 진행됨에 따라 증가하는 경향을 보였으나 통계학적으로 유의하지는 않았다. 4. 폐암환자에서 단일 종양표지자를 측정하는 것 보다 동시에 여러 종양표지자를 측정하는 것이 특이도는 떨어지나 민감도는 80.0%로 더 높은 것으로 나타났으며 정확도에는 큰 차이가 없었다. 양성 표지나 수에 따른 비교분석시 폐암의 상대 예측도는 두 표지자 양성인 경우가 76.5%, 3가지 표지자와 4가지 모든 표지자에서 양성으로 나온 경우는 100%로 나타났다. 본 연구 결과 CYFRA 21-1은 새로운 폐암의 종양표지자로 기존의 종양표지자 보다 민감도가 높고 비소세포암 특히, 편평상피세포암에 유용한 표지자로 사료되며, 폐암이 의심되는 환자에서 단일 종양 표지자를 측정하는 것 보다 수종의 종양표지자를 동시에 측정하는 것이 진단에 더욱 도움이 되리라 생각된다. Background: Cytokeratin 19 is a subunit of cytokeratin intermediate filament expressed in simple epithelia and their malignant counterparts. A fragment of cytokeratin subunit 19 can be measured in serum with a immunoradiometric assay using two mouse MoAb KS 19-1 and BM 19-21. Thus this cytokeratin 19 fragment is referred to as CYFRA 21-1. The aims of this study are to evaluate the clinical utility of CYFRA 21-1 in the diagnosis of lung cancer and to compare the diagnostic sensitivity and specificity of CYFRA 21-1 with those of CEA, SCC Ag, NSE according to histological type of lung cancer. Methods: In 40 patients with lung cancer(21 with squamous cell carcinoma, 10 with adenocarcinoma, 7 with small cell carcinoma, 2 with large cell carcinoma) and 40 patients with non-malignant lung disease, serum CYFRA 21-1 was measured by solid-phase immunoradiometric assay(CIS Bio International, France). Serum NSE and SCC Ag were measured by immunoradiometric assay, and CEA was measured by microparticle enzyme immunoassay. Results: 1) The mean value of CYFRA 21-1 was 22.08±43.00ng/mL in the lung cancer and 1.11±1.04ng/mL in me non-malignant lung disease group(P<O.O5). 2) Using the cut-off value of 3.3ng/mL, the sensitivity and specificity of CYFRA 21-1 were 55.0%, 96.7% in the lung cancer. The sensitivity of CYFRA 21.1 was 61.9% in squamous cell carcinoma 3) The level of CYFRA 21-1 was increasing tendency with the progression of stage in non-small cell carcinoma but statistically not significant. 4) Simultaneous determination of four tumor markers revealed increased sensitivity to 50.0% in lung cancer. As the number of positive markers was increased, the relative possibility of lung cancer was also increased. If two markers were positive, it increased to 76.5% and three markers were positive, it increased to 100%.5 Conclusions: CYFRA 21-1 is a useful serum marker for patients with lung cancer, especially in squamous cell carcinoma of the lung. The simultaneous measurement of CYFRA 21-1, CEA. SCC Ag and NSE would provide additional information for the diagnosis of lung cancer, especially in patients with high risk group of lung cancer.

참깨의 栽이 收量構成要素, 脂肪酸組成 및 잎마름病 發生에 미치는 影響

李徹熙,朴然圭,朴栽成 충북대학교 농업과학기술연구소 1994 農業科學硏究 Vol.12 No.1

This experiment was carried out to investigate the effect of planting time on growth character, yield components, fatty acid composition and leaf blight caused by Corynespora cassiicola in sesame. Dry weight of plant was the highest in sowing on April 25 and it was reduced with delaying sowing dates. Growth stage which increased dry weight of plant most rapidly was maturation period and capsule weight was drastically increased on 60 to 70 days after sowing. Corynespora leaf blight was severe with delaying the sowing date. Ansan variety had the highest occurrence rate of Corynespora leaf blight in sowing on June 25, 70 days after sowing and Danbaek variety in sowing on June 10, 80 days after sowing. Period when showed rapid increase of Corynespora leaf blight was from August 10 to August 20. Yield components were decreased with delaying the sowing date and capsule number per plant was most severely decreased with planting after June 10. Weight of 1,000 grains was decreased to 0.4-0.5g in sowing on June 25 compared to 2.8g of 1,000 grain weight in sowing on April 25. Maturation rate was also reduced from 87 to 97% in sowing on April 25 to 29-32% in sowing on June 25. Yield with sowing on April 25 was 81 and 89kg/10a with Ansan and Danbaek varieties, respectively, while it was decreased to 36 and 37kg/10a with sowing on June 25. Concentration of linoleic acid was high in sowing on June 25, while concentration of oleic acid was high in sowing on both May 10 and May 25.

교정치료에 따른 미맹출 하악 제3대구치의 위치 변화에 관한 연구

이경원,배성렬,김상철 대한치과교정학회 1996 대한치과교정학회지 Vol.26 No.1

임상교정에서의 원활한 치아배열을 도모하기 위하여 진단과 치료계획의 수립 방향에 따라 제1소구치 혹은 제2소구치 발치 또는 제2대구치 발치 또는 비발치로 치료가 진행된다. 이때 나타나는 하악제3대구치의 위치적 변화 특히 근원심, 협설측 경사도의 변화도를 알아보고자 163명의 교정환자 (비발치군 77례, 제1소구치 발거군 78례, 제2대구치 발거군 8례)의 치료전후 Pantomogram상을 분석하였다. 결과적으로 하악 제2대구치 발거군에서 치료전후 근원심 경사도의 변화가 컸으며, 하악 제3대구치의 초기 근심 경사도는 치료 전후의 근심경사도와 높은 상관성을 보였으며, 치료전후의 근심경사도 변화량과도 높은 상관성을 보였다. 비발치군과 제1소구치 발거군에서 치료전후의 협설경사도 변화의 차이가 인정되었다. 치료전후의 협설경사도 변화는 치료전의 협설 경사도, 치료후의 협설경사도, 치료후의 근심경사도, 치료전후의 근심경사도 변화량과 높은 상관성을 보였다. Most of orthodontic cases are treated with extraction of certain teeth, which influence the pre-eruptive movement of the lower third molar, The purpose of this study was to evaluate the positional change of lower third molar following orthodontic treatment. Pre- and post-treatment pantomograms of 163 orthodontic patients (77 nonextraction group, 78 first premolar-extraction group, 8 second molar-extraction group) were analyzed in terms of the mesidistal and buccolingual angles of lower third molar. The results were as follows. 1. The change of the mesiodistal angle of lower third molar by orthodontic treatment was significant in second molar-extraction group. 2. The mesiodistal angle of lower third molar in pre-treatment was significantly correlated to the mesiodistal angle in post-treatment and/or the change of the mesiodistal angle by treatment. 3. The change of the buccolingual angle of lower third molar by treatment was significant in non-extraction group or first premolar-extrction group. 4. The change of the buccolingual angle of lower third molar by treatment was significantly correlated to the mesiodistal angle in post-treatment, the change of the mesiodistal angle by treatment, the buccolingual angle in pre-treatment or the buccolingual angle in post-treatment.

EJB 래퍼 컴포넌트 지원 도구를 위한 CICS 코볼 시스템 및 SQL 문법 생성 규칙 개발

이신혜,배철성,정민수 慶南大學校 附設 工業技術硏究所 2003 硏究論文集 Vol.21 No.2

기존에 운용되고 있는 시스템은 새로운 컴퓨팅 기술 및 환경에 적응하기 위하여 현대화 되어야 한다. COBOL2EJB는 소프트웨어 컴포넌트로서 기존 시스템을 변화시킬 연계 도구이다. 이 COBOL2EJB는 코볼 문법을 중심으로 하고 있기 때문에 코볼에 내장되어 있는 CICS와 SQL을 지원하기엔 한계점이 있다. 이러한 한계점을 살펴보고 해결하기 위한 방안으로서 JJTREE를 소개한다. 그리고 COBOL2EJB 연계 도구의 사용성을 높이고자 IBM 코볼 소스에 내장된 CICS와 SQL을 처리할 수 있도록 JavaCC를 이용하여 문법 생성규칙을 확장하였다. With the rapid change of computing environment, much research is focusing on the modernization of the legacy systems Recently the software development mothods based on components have been used widely. A COBOL2EJB is used as a tool to transform the legacy system into the software component. Because of the lack of COBOL syntax generating rules, we can not fully support the software component The practical COBOL legacy system includes CICS and SQL commands as their additional source code. In this paper, we develop the advanced CICS/COBOL legacy system based on JavaCC to analyze a simple COBOL syntax. CICS/COBOL, and SQL

回轉 点熱源에 의한 2次元 非定常 熱傳導

李聖哲 全北大學校 1980 論文集 Vol.22 No.-

During the materials being worked by the tool of cutting, the heat and the unequal temperature distribution are generated on the cutting surface by the contact of the materials and the tool of cutting. In this paper, the temperature distribution on the surface by the moving point heat source is dealt with. And, at the constant angular velocity of the rotating point heat source, we find the temperature distribution on the cutting surface by using the Laplace transformation method.

개에서 발생한 이혈종의 임상적 관리

이우철,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 14-year-old male pomeranian was present with swollen left ear. The swelling occurred from base to apex of pinna. Otitis externa persisted for two years. Hematological and serum biochemistry values were not remarkable. The surgery treatment was the most appropriate method among indwelling drain, surgical, and steroid treatment in the aural hematoma because the dog was very sensitive to touching pinna and the size of aural hematoma. Longitudinal incision was applied after general anesthesia. Cefovecin was injected to prevent secondary infection. The outcome of surgery was good. There was no evidence of recurrence for one year.

개에 있어서 자궁축농증의 1례

이시예,김명철,정성목 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

A 7-years-old 4.5 kg female maltese dog with history of abdominal distension was referred to Veterinary Teaching Hospital of Chungnam National University. Hematologic showed mild increase in WBC. Mass with soft tissue density was observed near a bladder in abdominal radiography. Ultrasonography revealed enlarged uterus filled with hypoechoeic materials. It was diagnosed as pyometra and ovariohystectomy was performed. After surgery, the dog was recovered.

한국인에서 혈소판 당단백 Ⅱb/Ⅲa 유전자 다형성과 관동맥 성형술 후 재 협착과의 관계

이민수,이정우,김보영,임대승,강정아,김정희,김윤철,성보영,최성준,성인환,전은석 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2

Platelet aggregation is the final pathway of acute coronary syndrome such as acute myocardial infarction and unstable angina. Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and yon Willebrand factor and it plays an important role in platelet aggregation and in the pathogenesis of acute coronary syndrome. It is known that polymorphism of the gene that encoding platelet glycoprotein IIb/IIIa(PI^A1/A2) is strongly related to acute coronary syndrome in Caucasian, but not in Koreans. We investigated relationship between platelet glycoprotein llb/Illa gene polymorphism and restenosis of coronary artery after angioplasty in Koreans. Total 371 patients(M=251. F=120) were enrolled. Angioplasty group comprised 143 patients who underwent coronary angioplasty, and in the angioplasty group, restenosis group comprised with the 65 patients who had restenotic lesion over 50% of luminal diameter in follow-up coronary angiography. Normal group comprised 153 patients who had no significant angiographic lesion and variant angina group comprised 75 patients who were positive in ergonovine test. Genomic DNA was extracted from peripheral arterial blood. To determine the frequency of P1^A1/A2 genotype, polymerase chain reaction(PCR) was done and the product was restricted with Mspl. 3%. agarrose gel electrophoresis showed restriction fragment length polymorphism. Clinical profile and risk factor were also reviewed. Among all 371 patients of study group, genotype of only one patients in restenosis group if is proven to be PI^A1/A2 heterozygote. All patients of normal study group, no restenosis group, and the other patients in restenosis group have an PI^A1 homozygote genotype. In our study, platelet glycoprotein IIb/Illa polymorphism has no relationship with restenosis of the coronary artery after angioplasty in Koreans. But the genotypic frequency of platelet glycoprotein IIb/IIIa gene polymorphism in Koreans is concordant with that of previous studies.

급성 심근경색후 생존심근 진단에서 Dobutamine 심초음파도와 Thallium 심근스캔의 정확성 비교

이근,강덕현,송재관,이철환,최기준,홍명기,김재중,박성욱,박종훈,박승정 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2