세 종류의 측두엽 간질증후군 ; 내측두엽, 전외측두엽 및 후외측두엽 간질의 임상양상 및 전기생리학적 특징

이상건,김주용,김병건,이광우,노재규,명호진 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

알코올중독 환자의 예후 예측에 관한 연구(Ⅱ) : 가족력 및 DRD₂와의 관계를 중심으로

성상경,차성조,이규항,이정균 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.6

알코올중독 환자의 예후인자를 알아보기 위해 나이와 성별을 통제하여 음주군과 단주군 남자환자 각각 30명을 대상으로 비교 연구하였다. 양군간의 인구통계학적 특성, 음주력, 가족력, 자아강도 등의 차이 및 도파민 D2수용체 유전자 분포를 비교하였으며, 질병경과, 가족력 및 도파민 D2수용체 유전자와의 관련성을 알아보았다. 그 결과는 다음과 같다. 1) 단주군은 음주군에 비해 기혼율이 높았으며, 높은 경제상태, 높은 학력 등이 중요한 요소였으나 직업의 종류 및 종교에 있어서는 차이가 없었다. 2) 단주군은 음주군에 비해 과거 음주력상 최대 단주기간이 길었으나 평균 음주량이 더 많았다. 또한 음주군은 단주군에 비해 사회경제적 스트레스 및 정신적 불안정이 주된 음주 이유인 경우가 많았으나 음주기간, 음주양상, 음주시기, 음주시작 연령, 술의 종류에 있어서는 차이가 없었다. 3) 알코올중독의 가족력에 따른 비교에서 단주군과 음주군 사이에 유의한 차이는 없었다. 4) 단주군은 음주군에 비해 자아강도의 평균점수가 더 높았다. 5) 도파민 D2수용체 유전자의 A1 대립유전자 비교에서 단주군에서 A1 대립유전자의 이환율은 70%, 음주군에서는 60%였다. A1 대립유전자의 빈도는 각각 0.38과 0.42로 양군간에 차이는 없었다. 6) 알코올중독 가족력에 따른 도파민 D2 수용체 유전자분포 비교에서 가족력이 있는 군에 A1 대립유전자의 이환율은 70%, 빈도는 0.43이었고, 가족력이 없는 군에서는 이환율이 61%, 빈도는 0.38로 양군간에 유의한 차이는 없었다. 가족력이 있는 경우에 음주시작의 연령이 더 낮았으며 문제음주도 보다 일찍 나타났다. 그러나 평균 음주기간은 가족력이 없는 경우에 더 길었으며, 평균 음주량, 최고 단주기간 및 NAST 비교에서는 차이가 없었다. 결론적으로 알코올중독 환자의 긍정적 예후인자로 기혼, 높은 학력 및 경제상태, 과거 음주력상 보다 긴 단주 기간 및 강한 자아강도를 들 수 있었다. 반면에 직업, 종교, 알코올중독 가족력 유무, 음주기간, 음주양상, 음주시작 연령, 술의 종류 및 도파민 D2수용체 유전자 A1 대립유전자 분포 등에서는 알코올중독의 예후의 의미 있는 상관관계가 없었다. Objectives : The purpose of the study was to identify the prognosis-predicting indicators is alcoholics by the correlation between prognosis and demographic characteristics, ego strength, family history and distribution of dopamine D2 receptor gene A1 allele. Methods : The subjects were composed of 60 alcoholics including 30 psychiatric inpatients(drinking group) and 30 alcoholics abstinent for 6 months or more after discharge(abstinent group). They were investigated with interview, questionnaire, blood sample and review of their charts. Results : The results were as follows ; 1) The abstinent group had higher rate of married state, higher economic status and longer education years than the drinking group. There were no differences in occupation and religion between the two groups. 2) There were no differences between the abstinent group and drinking group according to alcoholic family history. 3) The abstinent group had higher mean score in ego strength scale than the drinking group. 4) In comparision of dopamine D2 receptor gene A1 allele, the prevalence of A1 allele was seventy percent and the frequency was 0.38 in the abstinent group. The prevalence of A1 allele was sixty percent and the frequency was 0.42 in the drinking group. Both groups were not significantly different in A1 allele prevalence and frequency. 5) In comparision of dopamine D2 receptor gene A1 allele according to alcoholic family history, the prevalence of A1 allele was seventy percent and the frequency was 0.43 in the family history positive group. The prevalence of A1 allele was sixty-one percent and the frequency was 0.38 in the family history negative group. Both groups were not significantly different in A1 allele prevalence and frequency. Conclusions : With the above results, the authors think that successful prognostic indicators of alcoholics are married state, higher economic status, longer education years, longer abstinenence period in past history, and strong ego strength. But family history and distribution of dopamine D2 receptor A1 allele were not significantly related to the prognositc indicators of alcoholics.

무증상 당뇨환자의 T 반사 변화

안규환,조용진,김상화,사은희,임용빈,김대성,정대수,박규현 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

로봇의 3D 물체인식을 위한 Vision Algorithm

성윤경,이규태 朝鮮大學校 機械技術硏究所 2006 機械技術硏究 Vol.9 No.1

The robot and machine vision technology has been developed for automatic fruit harvest. The most important subject in developing fruit harvesting robots is accurately to locate fruits on the given coordinate system. In this paper, we employ average color values (Red. Green, Blue), area, center position, compactness, perimeter and chain-coding information of specific regions, to detect and locate fruits in space. Especially, a new approach is presented to judge whether an extracted region is, overlapped or partially occluded by deleting or separating the region of an image.

후두와 종양에서의 무언증 : 증례 보고 A Case Report

성연상,강재규,도종웅,김기욱,김상진 최신의학사 1991 最新醫學 Vol.34 No.1

선천성 수근관 증후군 1례 보고

이규훈,황치문,김민석,김희상,안경회 大韓再活醫學會 1998 Annals of Rehabilitation Medicine Vol.22 No.3

트랙터의 로터리 驅動을 위한 PTO 시스템과 油壓驅動 시스템의 性能 試驗에 關한 硏究

成始興,崔圭洪 建國大學校 附設 自然科學硏究所 1993 建國自然科學硏究誌 Vol.4 No.-

엔진 회전속도 변동에 따른 PTO 회전수, PTO 토크, PTO 출력 및 연료 소비율을 측정하여 기계식과 유압식의 동력 특성을 비교, 분석한 결과는 다음과 같다. 1) 기계식, 유압식 모두 엔진의 회전 속도가 증가할수록 PTO 회전수는 증가하는 경향으로 나타났으며, 기계식이 변속단수 변동에 따른 엔진의 회전속도 폭이 안정적으로 나타난 대 반하여 유압식은 다소 크게 나타났다. 2) 엔진의 회전속도가 증가할수록 기계식, 유압식의 토크는 반비례 관계로 나타났다. 3) 최대 출력은 기계식의 경우 PTO 1, 2, 3단 순으로 나타난 데 비하여 유압식은 PTO 3, 2, 1단 순으로 나타나 PTO 변속 단수가 증가될수록 출력도 증가하는 것으로 나타났다. 4) 연료 소비율은 기계식, 유압식 모두 엔진의 회전수가 증가됨에 따라 연료 소비율은 어느 일정한 회전수 부근에서 최소가 된 후 다시 증가하는 경향으로 나타났다. 5) 유압구동 로터리의 효과적인 이용을 위해서는 유압펌프가 항상 고속으로 회전할 수 있도록 로터리는 어느 일정 회전속도를 유지시켜 작업하는 것이 필요할 것으로 판단되었다. 6) 유압식의 경우 유압펌프의 회전속도가 증가함에 따라 출력 및 연료 소비율이 향상되는 성으로 나타나 기계식에 비하여 효율이 크게 뒤떨어지지 않아 실용화의 가능성이 큰 것으로 생각되었다. The speed of revolution, the PTO torque, the PTO output power, and the specific fuel consumption caused by the variation in the revolution of an engine speed were measured. Therefore, the overall dynamic performance of the hydraulic PTO system was compared and analyzed with that of mechanical PTO system. The results are summarized as follows : 1) Both RPM of the hydraulic PTO and that of the mechanical one increased linearly as the engine speed increased. The engine speed from the variation of a mechanical type was saftly and small changed, but that of a hydraulic type was high changed. 2) Both torques of the hydraulic PTO system and those of the mechanical one decreased linearly as the engine speed increased. 3) The maximum power of the mechanical PTO system was the highest at the first gear of the mechanical one followed by the second one and the third one. However, that of the hydraulic PTO system was at the third gear followed by the second one and the first one. It means that the output power of a hydraulic PTO system increased as the variable PTO gear was increased. 4) After the specific fuel consumption decreased gradually to the specific point, which was required the lowest fuel consumption, then it increased as the engine speed increased. 5) To utilize effectively the hydraulic drive system, this system needs always to be kept revoluting constantly at an engine speed for hydraulic pump to rotate at the high speed. 6) The output power and the specific fuel consumption were improved by using the hydraulic system as the revolution of the engine speed was increased. The performance of hydraulic system was not significant of that of mechanical system. Therefore a hydraulic PTO system, which is convenient for a machine attached it to control automatically, would be utilized in future.

비글개에서 신원방우황청심원의 급성 및 아급성독성시험

성하정,권오경,방명주,곽형일,이진영,신대희,박대규,정규혁,윤효인,조명행 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

Single and 4 weeks oral administration of New wonbangwoohwangchungsimwon (NSCH) which was used l-muscone as substitutive material of musk, to beagle dogs of both sexes were performed to investigate both acute and subacute toxicity. Beagle dogs (3 males and 3 females) in acute experiments were administered orally with sinlge dose of 2,000 ㎎/㎏ and groups of 9 male and 9 female beagle dogs in subacute experiments were given daily different dosage of NSCH, 160 ㎎/㎏/day (low dosage group), 400 ㎎/㎏/day (middle dosage group), 1,000 ㎎/㎏/day (high dosage group) once a day for 4 weeks by oral route according to the Established Regulation of Korea Food and Drug Administration (1996. 4. 16). LD_50 value for beagle dogs was more than 2,000 ㎎/㎏ per oral for both male and females. In animals administered with NSCH, there were neither dead animals nor significant changes of body weights. In addition, no differences were found between control and treated groups in clinical sign, urinalysis, eye examination, hematology, serum chemistry, organ weight and other fingings. No histological lesions were observed in both control and treatment groups. Above data strongly suggset that NSCH in beagle dogs is considered to be safe.

위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

법랑아세포종의 임상병리학적 연구

성일용,류성호,신상훈,김욱규,김종렬,정인교,변기정 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.1

The authors analyzed retrospectively the 60 patients with ameloblastoma who were treated at Department of Oral and Maxillofacial Surgery, Pusan National University Hospital from MArch, 1990 to December, 1995. The results obtained were as follows: There were 26 males (43.3%) and 34 females (56.7%). The peak age of patients was the third decade (41.7%). The majority of cases occurred in the mandible 93.3%, especially in the angle region (91.1%). Eighteen of 60 patients (30.0%) were associated with an impacted tooth, by impacted 3rd molar teeth (16.6%), molar (10.0%), and premolar and canine (3.4%) in order., Fifteen of 60 patients (25%) were associated with an odontogenic cyst, by dentigenous cyst(13.3%), odontogenic keratocyst(8.4%), and radicular cyst(3.3%) in order. Radiographically, there were 32 unilocular types(54.2%) with average age of 24.9±10.8 years, 14 multilocular types(23.7%) with average age of 35.7±17.7 and 13 mixed types(22.0%) with average age of 41.4±15.8. Histopathologically, there were 42 follicular types(70.0%) with average age of 33.7±15.1 years and 18 plexiform types(30.0%) with average age of 26±14.6. Conservertive treatment was performed in the 33 patients(55.0%) and their average age was 25.2±13.9 years and radical treatment in the 27 patients(45.0%) and their average age was 39.3±41.8. Overall recurrence rate was 10%. A consistent correlation between the age of the patient and the radiographic or histologic type of mandibular ameloblastoma was observed. There was a tendency for ameloblastomas of the follicular type to show a multilocular or mixed appearance and for those of the plexiform type to show a unilocular appearance.