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神經外科領域에서의 Minocycline의 臨床效果 : An Electron Microscope Study
都鍾雄,鄭相燮,金相喆,李揆彰,李憲梓 최신의학사 1975 最新醫學 Vol.18 No.8
Minocycline, 7-dimethylamino-6- deoxy-6-demethyltetracycline is a new semisynthetic tetracycline which has a broad antibacterial spectrum. It is effective in vitro aganist many Gram-positive- and Gram-negative bacteria including tetracycline-resistant staphylococci and pseudomonas species. Several reports in the literature attest to its in vitro effectiveness, suggesting that it is the most effective tetracycline now available for clinical use. Animal studies have been reported on its effectiveness in vivo, but there are few reports in the clinical literature of the use of Minocycline in the, treatment of human diseases except urinary and upper respiratory tract infections. , In this report, the. in vitro activity of Minocycline against a number of pathogenic bacterial I strains, compared with various antibiotics, is described as well as the clinical- effectiveness- of this drug_ in the. treatment of various infectious diseases in the neurosurgical field. 1) In various neurosurgical infectious diseases, 69 pathogenic bacterial strains were isolated from 52 patients. Staphyloccus aureus was the most common organism(42%) and pseudomonas, E. coli, and proteus strain followed in order. 2) In antibiotic sensitivity of 69 strains tested, Minocycline showed the most broad antibacterial spectrum and highly sensitive to various organisms especially staphylococcus aureus and pseudomonas strain compare with gentamycin, ampicillin and knamycin. 3) Forty out of 52 patients responded well clinically to Minocycline theraphy within 15 days of treatment and no serious side effects were noted except ocassonal.
소아에서 발생한 거대한 뇌동맥류성 혈관기형 : 증례 보고 Case Report
도종웅,한윤선,김영수,이헌재 대한신경외과학회 1977 Journal of Korean neurosurgical society Vol.6 No.1
A giant aneurysmal cerebral arteriovenous malformation in the left parieto-occipital region is described in a 4 year old child, including resolution of the alternating hemiparesis and left ventricular hypertrophy of the heart following sucessful removal of the malformation by microsurgical technique. This arteriovenous malformation has a large aneurysmal sac, 6×5×4㎝. in size with several feeders from branches of the left middle and posterior cerebral arteries and drains directly into the straight sinus. So we have proposed to call it "a giant aneurysmal cerebral arteriovenous malformation".
단파를 이용한 Clonic Facial Spasm 치험 1예
도종웅,박종운,김상철,정상섭,이규창,이헌재 대한신경외과학회 1975 Journal of Korean neurosurgical society Vol.4 No.2
Clonic facial spasm had attracted for attention of neurosurgeons for a long time. However the optimal way of treatment is not established yet. In this report, we are describing a case of clonic facial spasm treated by making a lesion on the facial nerve at stylomastoid foramen with radiofrequency lesion generator which has been applied for percutaneous cordotmy or percutaneous gasserian ganglionotomy.
제4뇌실 상의세포종(Ependymoma)수술후 발생한 파종성 혈관내 응고병증 : 증례 보고 Case Report
도종웅,김영수 대한신경외과학회 1979 Journal of Korean neurosurgical society Vol.8 No.1
Disseminated intravascular coagulation (DIC) occurs rarely in head injury, but has not previously been reported following elective brain tumor surgery. There have been two case reports of DIC associated with primary brain tumors in the world literature. Vardi et al. (1974) reported an autopsy case (19F) of DIC associated with a medically treated oligodendroglioma in the left parietotemporal lobe invaded the ventricle. The second case (23F) was reported by Matjasko and Ducker and the case developed fulminating DIC during the removal of a third ventricular perihypothalamic oligodendroglioma. They couldn't get autopsy permission. The authors report the occurrence of fulminating DIC following removal of a fourth ventricular Ependymoma in a 5-yr. old boy, which was conformed by autopsy. This may be the third case of DIC associated with primary brain tumor and the first autopsy case of DIC developing following removal of Ependymoma in the fourth ventricle.
도종웅 대한신경외과학회 1980 Journal of Korean neurosurgical society Vol.9 No.2
CT scan has recently revolutionized diagnostic pediatric neurology. Thus the magnitude of childhood stroke may be larger than that of previously realized. The early recognition and treatment of major risk factors become important in order to prevent stroke in children. We have experienced 7 cases, of childhood stroke which were confirmed by CT scan.
^(169)Yb-DTPA를 이용한 Cisternography
도종웅,김상철,이규창,이헌재,양병철,박창윤,최병숙 대한신경외과학회 1977 Journal of Korean neurosurgical society Vol.6 No.1
The radioactive nucleid cisternography is being used as a diagnostic adjunct of CSF rhinorrhea and otorrhea, hydrocephalus, patency after ventricular shunt operation, brain tumor and cangenital anomalies of the central nervous system. In numerous radioactive nucleids, ^(169)Yb-DTPA is known to have moderately effective half life, high energy level for scintilation, and pure r-emitter in subarachnoid space. Authors review some clinical advantage of cisternography using ^(169)Yb-DTPA applied in the diagnosis of CSF rhinorrhea and otorrhea, hydrocephalus, CSF fistula and patency after ventricular shunt operation.
도종웅,김영수 대한신경외과학회 1979 Journal of Korean neurosurgical society Vol.8 No.2
In lumbar myelography many side effects occures in about half the patients examined with modern contrast media. We used amipaque, water soluble contrast media for lumbar myelography in 14 patients with herniated lumbar disc. At myelography with amipaque the side effects are usually minor and serious adverse reactions are rare. Amipaque is of greatest advantage in examination of small structures such as roots, root pockets and blood vessels in spinal subarachnoid space.