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      • KCI등재

        열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

        배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

        Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

      • 체외 충격파 쇄석기에 의해 발생된 음향 흐름 현상 연구

        최민주,이승환,홍경진,김호찬,박재우,이헌주 제주대학교 공과대학 첨단기술연구소 2001 尖端技術硏究所論文集 Vol.12 No.2

        Acoustic streaming produced by an extracorporeal shock wave lithotripter was visualized for the first time in the present study. It was observed that the streaming velocity increased with the shock wave amplitude and was reaching up to 3 cm/s at the highest output setting of the lithotripter.

      • 웨이브렛 변환을 이용한 초음파의 조직 특성화 연구

        최민주,홍경진,박재우,이헌주 제주대학교 공과대학 첨단기술연구소 2001 尖端技術硏究所論文集 Vol.12 No.2

        본 논문에서는 조직의 특성화 변수로 산란체의 간격에 대해 고려하였다. 조직 내에서 산란된 초음파 신호를 분석하여 특정 위치에서의 산란체의 간격을 추정하였다. Born approximation 이용하여 얻어진 초음파 반사 신호를 이용하여 모의 실험을 하였다. 산란체의 위치는 초음파 신호를 웨이브렛 변환 후 여러 단계에서 반복적으로 출현하는 높은 계수 값의 위치로부터 예측하였다. 시뮬레이션 결과 본 연구에서 개발된 알고리즘은 산란체의 간격이 초음파의 파장보다 큰 경우 정확하게 산란체의 간격을 추정하고 있음을 확인하였다. 산란체 간격 추정 알고리듬을 이용하여 조직내 산란 간격을 영상 변수로 한 초음파 영상을 구성하고 임상적 유용성을 고찰하였다.

      • 만삭 신생아의 기흉

        최우경,홍찬의,이동진,허남진,이영환 영남대학교 의과대학 2005 Yeungnam University Journal of Medicine Vol.22 No.2

        Background: This study was performed to evaluate the incidence and clinical characteristics of symptomatic pneumothorax in the full-term neonate. Materials and Methods: We retrospectively reviewed the medical records of 32 symptomatic pneumothorax patients in the full term neonates who admitted to the neonatal intensive care unit in Ulsan Dong Kang General Hospital from January, 2000 to December, 2004. The subjects were divided into two groups according to underlying causes; spontaneous pneumothorax group and secondary pneumothrax group, then each clinical characteristics were assessed. Result: Spontaneous pneumothorax patients were 10(31%) and secondary pneumothorax patients were 22(69%). Overall incidence of spontaneous pneumothorax was 0.4%. Most common cause of secondary pneumothorax was pneumonia. Twelve causes(54.5%) among secondary pneumothorax patients were associated with mechanical ventilator care. Clinical characteristics, courses and managements were similar between two groups, but more shorter duration of admission and chest-tube insertion in spontaneous pneumothorax group Conclusion: The patient with symptomatic pneumothorax needs careful observation and proper management with or without underlying respiratory diseases

      • 氣化器붙이 機關의 共給燃料 氣化率에 關한 基礎硏究

        崔鍾宇,朴涇錫 慶熙大學校 1985 論文集 Vol.14 No.-

        This study has been made to observe the effect of vaporization of injected fuel under the several important factors on the carburetor for gasoline engine. To measure the vaporization rate of mixture in the carburetor, the key point of consideration for divising the cyclone which is devised to be able to separated injected fuel with drop diameter 10-30㎛. By using a transparent tube type model of the carburetor, like one of conventional gasoline engines, this experiment has been performed. Results of the study are summarized as follow. 1. In the conditions of this study, Ve=12.6 - 50.4㎧, θ=30 - 90, t = 25.℃ - 50℃, the vaporization rate is 10-50% 2. The vaporization rate increase in proportion to decreasing of throttle valve angle, to rising air temperature and growing air - fuel ratio. 3. When air velocity is increased, the injected fuel flows with thin thickness of liquid film on the inner wall of intake pipe. As air temperature is increased, it flows with more thin.

      • 一酸化炭素가 中樞神經系의 dopaminergic system에 미치는 影響

        崔暻奎,李愚馨 梨花女子大學校 韓國生活科學硏究院 1989 韓國生活科學硏究院 論叢 Vol.44 No.-

        일산화탄소는 인체의 여러 기관에 손상을 주나 그 중에서도 특히 중추신경계 손상에 의한 다양한 임상증상이 특징적이다. 이때에 나타나는 증상이 중추신경계에서의 신경전달물질의 변동시에 나타나는 증상과 유사하고 또 이에 대한 약물치료에 호전을 보이는 경우가 있어 일산화탄소 중독시에 중추신경계에서의 신경전달물질의 함량의 변동이 예상된다. 저자들은 이러한 가설하에 2,000ppm의 일산화탄소 농도에서 흰쥐를 중독시킨 다음 선조체, 흑질 및 뇌척수액에서 dopamine과 그 대사물질인 DOPAC, HVA의 함량을 측정한 결과 일산화탄소가 선조체에서 dopamine의 분비를 억제하고 또 대상과정에서 COMT를 억제하는 효과가 있음을 알 수 있었다. The acute and delayed effects of Carbon Monoxide intoxication on dopamine and its metabolites in striatum, substantia nigra and cerebrospinal fluid were examined in the rat. The acute effects of Carbon Monoxide intoxication were examined right after the intoxication and delayed effects were examined 2 weeks after the Carbon Monxide intoxication. At the acute stage of Carbon Monoxide intoxication, dopamine and DOPAC levels of striatum and DOPAC level of CSF were significantly greater than those of the control group. At the delayed stage of Carbon Monoxide intoxication, dopamine and DOPAc levels in the striatum were significantly greater than those of the control rats. The changes of dopamine and its metabolite levels in the striatum suggested that Carbon Monoxide inhibited not only dopamine release in dopaminergic neurons but also COMT in the extraneuronal metabolic pathway.

      • 시판용 상토 종류가 배추 유묘기 묘소질에 미치는 영향

        이상우,강호종,안상열,채윤석,윤재길,최경옥 진주산업대학교 농업기술연구소 2007 農業技術硏究所報 Vol.20 No.-

        시중에 판매되고 있는 상토는 제조 회사에 따라 재료의 구성 및 혼합 비율이 다르다. 시판용상토를 제조사별로 구입하여 상토 제조사에 따라 배추 육묘기 묘소질에 미치는 영향에 대해 조사하였다. 상토 제조사 별로 배추의 지상부 및 지하부의 생육에 많은 차이가 있었다. 그리고 엽록소 함량 및 단백질 함량에도 차이가 많았으며, 엽록소 및 단백질 함량이 높았던 상토에서 배추의 생육이 좋았다. 상토 제조사별로 상토의 재료 및 혼합비율에 따라 배추의 유묘기 생육에 많은 영향을 미치는 것으로 나타났다. The substrate is very important to grow seedling because of directly effect on seedling quality of Chinese cabbage. The substrates manufactured by the companies consist of different materials and mixing ratios. This study was conducted to observe the seedling quality of Chinese cabbage by using of the kinds of substrate. The number of leaf, leaf area, fresh weight, dry weight, root length, root weight and T/R ratio of the seedling were shown in different from each substrate manufactured by the companies. And chlorophyll and protein content of the seedling were also shown in different from substrates supplied from the companies, respectively. Substrate which was high in that was also higher in seedling quality. The material and mixing ratios of substrate effected on the growth of cabbage

      • KCI등재
      • KCI등재

        상아질 접착제의 용매 증발이 접착 효율에 미치는 영향

        조민우,김지연,김덕수,최경규 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.5

        연구목적: 본 연구는 상아질 접착제의 잔류 용매가 접착 효율에 미치는 영향을 평가하고자 하였다. 연구 재료 및 방법: 본 연구에서는 5세대 2단계 산부식형 접착제와 7세대 단일과정 자가부식형 접착제를 사용하였다. 상아질 접착제의 증발률과 전환률, 적용 후 용매의 공기건조 방법에 따른 미세인장결합강도를 측정하였으며 접착 계면을 FE-SEM을 이용하여 관찰하였다. 결과: 1. 시간에 따라 접착제의 증발률은 증가하나 접착제의 종류에 따라 증가 양상이 서로 달랐다. 2. 대부분 전환률은 증발률에 비례하는 경향을 나타내었다. 3. 공기건조 방법에 따라 결합강도는 대부분 under군, control군, over군 순으로 증가하는 양상을 나타내었다. 4. FE-SEM에서 아세톤을 용매로 사용하는 접착제는 공기건조 방법에 따라 droplet이나 gap이 관찰되었다. 결론: 상아질 접착제의 잔류 용매는 접착 효율에 부정적인 영향을 미치기 때문에, 상아질 접착제의 선택과 사용 시 용매의 종류와 특징에 대한 적절한 이해가 필요할 것이다. Objectives: The purpose of this study is to evaluate bonding efficacy by means of measuring the effect of remained solvent on Degree of conversion(DC) and μTBS and FE-SEM examination. Materials and Methods: Two 2-step total etching adhesives and two single-step self etching adhesives were used in this study. First, volume weight loss of 4 dentin adhesives were measured using weighting machine in process of time in normal conditions and calculate degree of evaporation (DE). Reaction/reference intensity ratio were measured using micro-Raman spectroscopy and calculate DC according to DE. Then 2 experimental groups were prepared according to air-drying methods (under, over) and control group was prepared to manufacturer's instruction. Total 12 groups were evaluated by means of micro tensile bond strength and FE-SEM examination. Results: Degree of evaporation (DE) was increased as time elapsed but different features were observed according to the kind of solvents. Acetone based adhesive showed higher DE than ethanol and butanol based adhesive. Degree of conversion (DC) was increased according to DE except for S³ bond. In μTBS evaluation, bond strength was increased by additional air-drying. Large gaps and droplets were observed in acetone based adhesives by FE-SEM pictures. Conclusions: Additional air-drying is recommended for single-step self etching adhesive but careful consideration is required for 2-step total etching adhesive because of oxygen inhibition layer. Evaporation method is carefully chose and applied according to the solvent type.

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