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CRST 증후군에 대한 Reserpine 의 동맥내 주사효과
박재우,신실,손숙자 대한피부과학회 1981 大韓皮膚科學會誌 Vol.19 No.6
The CRST syndrome, first reported by Winterbauer, represents a benign variant of scleroderma and consists of calcinosis(C), Raynauds phenomenon(R), sclerodactyly(S) and telangiectasia(T). The authors report a case of CRST syndrome confirmed by both clinical and histopathological findings. A 62-year-old female developed subcutaneous nodules on both elbow and knee joints, Raynauds phenomenon, sclerodactyly with acrosclerosis and scleroderrnatous changes on both hands and forearms and telangiectasia on the face, neck, and hands of 15 years duration, but she had no difficulty in swallowing. The authors treated a case of CRST syndrome with weekly intra-arterial administration of reserpine and were impressed not only by the marked loosening of the skin but also by the striking effect on the Raynauds phenornena; the latter disappeared within a few weeks of treatment.
박재우,윤성우,김진성,류봉하 대한침구의학회 2008 대한침구의학회지 Vol.25 No.3
Objectives : These days, herbal acupuncture therapy is widely applied to many diseases and symptoms by Korean medical doctors in Korea. The aim of this study was to demonstrate the effect of Carthami-Semen herbal acupuncture(CSHA) on chronic constipation. Methods : This single-blind placebo-controlled randomized parellel study enrolled 24 adults with chronic constipation. After one week’s run-in period, they were randomly assigned to receive CSHA therapy, or placebo therapy for 4 weeks by 2 times per week. After completing 4 week’s therapy, 2 week’s follow-up period was continued. During study, defecation frequency, consistency and ease of evacuation were checked before study, every week and follow-up periods. Also, the VAS of constipation, quality of life(QoL) and heart rate variability (HRV : low frequency, high frequency) were checked 3 times totally. Finally, 21 subjects completed the protocol and 20 subjects were analyzed.(1 subject is excluded for analysis because of not following the protocol.) Results : In CSHA group, defecation frequency (continued after 1 week), consistency and ease of evacuation (at 1 week after and follow-up) were increased significantly. The VAS of constipation in CSHA group was significantly decreased. There was no significant change at QoL and HRV. Conclusions : CSHA therapy was effective in treating adults with chronic constipation. Study that have larger case number and longer follow up will be needed in the future.
건칠(乾漆) 추출물(Nexia)의 독성 실험과 급성 림프 구성 백혈병환자의 임상증례군 보고
박재우,김경석,정현식,최원철,윤성우,Park, Jae-Woo,Kim, Kyung-Suk,Jung, Hyun-Sik,Choi, Won-Cheol,Yoon, Seong-Woo 대한암한의학회 2006 大韓癌韓醫學會誌 Vol.11 No.1
This study was undertaken to evaluate safety and antitumor activity of Nexia, a processed extract of Rhus verniciflua STOKES by heating according to Korean patent 0504160 through toxicology, cancer research and clinical application. Nexia did not exhibit any toxicological symptoms through 13 week continuous treatment, dosage accumulation study and anaphylaxis response. The lifespan of four patients with acute lymphocytic leukemia under complete remission were 110, 83, 97, and 86 months after treatment of Nexia, respectively. These data suggest that Nexia, a processed extract by removing allergen from Rhus verniciflua STOKES, may have safety and antitumor activity and also still need continuous study on its mechanism and clinical trial.
박재우,윤성우,김진성,류봉하,Park, Jae-Woo,Yoon, Seong-Woo,Kim, Jin-Sung,Ryu, Bong-Ha 대한침구의학회 2008 대한침구의학회지 Vol.25 No.5
Objectives : These days, herbal acupuncture therapy is widely applied to many diseases and symptoms by Korean medical doctors in Korea. The aim of this study was to demonstrate the effect of Carthami-Semen herbal acupuncture(CSHA) on chronic constipation. Methods : This single-blind placebo-controlled randomized parellel study enrolled 24 adults with chronic constipation. After one week's run-in period, they were randomly assigned to receive CSHA therapy, or placebo therapy for 4 weeks by 2 times per week. After completing 4 week's therapy, 2 week's follow-up period was continued. During study, defecation frequency, consistency and ease of evacuation were checked before study, every week and follow-up periods. Also, the VAS of constipation, quality of life(QoL) and heart rate variability(HRV : low frequency, high frequency) were checked 3 times totally. Finally, 21 subjects completed the protocol and 20 subjects were analyzed.(1 subject is excluded for analysis because of not following the protocol.) Results : In CSHA group, defecation frequency(continued after 1 week), consistency and ease of evacuation(at 1 week after and follow-up) were increased significantly. The VAS of constipation in CSHA group was significantly decreased. There was no significant change at QoL and HRV. Conclusions : CSHA therapy was effective in treating adults with chronic constipation. Study that have larger case number and longer follow up will be needed in the future.
박재우,채명진,이규,조문영,Park, Jae-Woo,Chae, Myung-Jin,Lee, Giu,Cho, Moon-Young 한국건설관리학회 2012 한국건설관리학회 논문집 Vol.13 No.6
'시설물안전관리에관한특별법'에 정의되어 있지 않고 1, 2종 교량에 포함되지 않는 기존의 소규모 교량은 유지관리 관련 제도적 근거가 미비하여 중차량 하중에 의한 구조적 손상이나, 재료적 노후도 관리가 적절히 이루어지지 않고 있다. 그러나 이들 교량의 상당수가 인구 밀접지역에 위치하고 있으며 그 수량이 1, 2 종 시설에 비하여 많은 수를 차지하고 있으며 또한 도심지에 위치하고 있어 사고 발생시 사회적, 경제적 손실은 매우 크다. 이 논문에서는 이들 소규모 교량도 국가 자산의 중요한 일부로 인식하여 시기적절한 유지관리 활동이 가능하도록 장기성능예측에 필요한 핵심 파라미터 분석을 위한 테스트베드를 구축하였다. 테스트베드는 소규모 교량 형식의 대부분을 차지하고 있는 콘크리트 교량을 대상으로 하였으며, 장기 성능에 영향을 미치는 요소로 중차량에 의한 과도한 반복하중에 의한 피로 누적을 하중 마일리지 개념을 도입하여 성능 저하를 예측하고, 염해에 의한 재료적 노후도를 평가할 수 있도록 마련하였다. 테스트베드를 통한 최종 결과물을 도출하기 위해서는 필연적으로 장기적인 성능 관측이 요구되므로, 본 연구는 소규모 교량의 자산관리에 필요한 장기성능예측 파라미터를 추출하기 위한 제반 연구의 기반 구축에 의의가 있다.
불안정 애착이 강박적 성행동에 미치는 영향: 외로움과 수용의 매개 효과
박재우 사단법인 한국융합기술연구학회 2024 아시아태평양융합연구교류논문지 Vol.10 No.11
본 연구의 목적은 성인 애착 스타일이 강박적 성행동에 미치는 영향과 외로움과 수용의 매개효과를 검증하는 것이었다. 이를 위해 20~39세 성인 300명을 대상으로 자기보고식 척도를 실시하고 수집된 자료를 분석하였다. 연구에 사용된 척도는 성인 애착 스타일 척도, 강박적 성행동 장애 척도, 외로움 척도, 수용 척도를 사용하였다. 구조방정식 모형 분석을 실시하였으며 연구 결과는 다음과 같았다. 첫째, 불안 애착은 강박적 성행동과 정적인 상관관계를 보였다. 둘째, 회피 애착은 강박적 성행동과 부적인 상관관계를 보였다. 셋째, 불안 애착에서 외로움으로, 수용에서 강박적 성행동으로의 순차적 매개효과가 그 순서대로 유의미했다. 넷째, 회피 애착에서 외로움으로, 수용에서 강박적 성행동으로의 순차적 매개효과도 유의미했다. 본 연구 결과에서 심리적 수용의 매개효과가 유의미하다는 점은 앞으로 이 분야의 치료에 있어서 수용전념치료를 적극적으로 적용할 필요성을 시사한다. 또한 강박적 성행동 문제를 다룸에 있어서 내담자의 외로움을 개선할 수 있는 개입이 중요하다는 점이 시사된다. 본 연구의 추가적인 함의와 한계를 논의에 제시하였다. This study aimed to verify the effects of adult attachment styles on compulsive sexual behavior and the mediating effects of loneliness and acceptance. To this end, the self-reporting scale was administered to 300 adults aged 20 to 39, and the collected data were analyzed. The measures used for the study included the adult attachment style scale, the compulsive sexual behavior disorder scale, the loneliness scale, and the acceptance scale. The structural equation model analysis was conducted. The results of the study are as follows: First, anxious attachment was positively correlated with compulsive sexual behavior. Second, avoidant attachment was negatively correlated with compulsive sexual behavior. Third, the sequential mediating effects from anxious attachment to loneliness to acceptance of compulsive sexual behavior disorder were significant in that order. Fourth, the sequential mediating effects from avoidant attachment to loneliness to acceptance and compulsive sexual behavior disorder were also significant. The fact that the mediating effect of psychological acceptance was verified in the results of this study suggests the need to actively apply acceptance and commitment therapy in the treatment of this field in the future. It also suggests that interventions that can improve the client's loneliness are important in dealing with compulsive sexual behavior problems. Additional implications and limitations of this study were presented in the discussion.
항공기 지연 개선을 위한 적정 수준의 Turnaround Time 도출 연구
박재우,조현수,구성관 한국항공운항학회 2024 한국항공운항학회지 Vol.32 No.3
The aircraft delay rate has increased nearly three times in 2023 due to change in Korea policy of delay criteria. One of the primary causes of delays in domestic flights is related to reactionary delays, with Turnaround Time being a key factor. To mitigate reactionary delays and reduce aircraft delays, it is essential to establish an appropriate Turnaround Time and integrate it into flight schedules. This study aims to analyze the appropriate Turnaround Time for aircraft operating at Gimpo, Gimhae, and Jeju International Airports, which handle a high frequency of domestic flights. The research applies air traffic simulation, using variables such as current flight schedules, actual flight times, Turnaround Time, and flight routes to simulate actual conditions. Based on this analysis, the study seeks to identify the fitting Turnaround Time across various scenarios. The findings are expected to address reactionary delays and help reduce overall delay rates in domestic flights.
탄소섬유쉬트로 구속된 콘크리트충전 원형강관기둥의 단조압축실험
박재우,홍영균,홍기섭,최성모 한국지진공학회 2009 한국지진공학회논문집 Vol.13 No.5
본 연구에서는 기존 원형 CFT기둥 실험체와 탄소섬유쉬트로 추가구속된 원형 CFT기둥 실험체의 단조압축거동 및 압축내력평가에 관한 실험을 수행하였다. 실험변수는 탄소섬유쉬트 보강겹수와 직경-두께비이며, 실험변수에 따라 총 10개의 실험체를 제작하여 단조압축실험을 수행하였다. 실험을 통하여 기존 CFT 실험체와 탄소섬유쉬트로 구속된 CFT 실험체의 파괴거동, 하중-축변위 곡선, 최대내력, 변형성능을 비교한다. 끝으로 탄소섬유쉬트의 추가구속을 통해 기둥의 국부좌굴을 지연시켰으며 구속효과로 인해 내력은 상승하는 것으로 나타났다. This paper presents the results of an experiment comparing the current circular CFT columns and circular CFT columns that were additionally confined by carbon fiber sheets (CFS) under axial loading. The main experimental parameters are the numbers of CFS layers and the diameter-to-thickness ratio. 10 specimens were prepared according to the experimental parameter plans, and axial compression tests were conducted. From the tests, the failure procedure, load-axial deformation curve, maximum axial strength, and deformation capacity of the CFT columns and confined CFT columns were compared. The test results showed that the maximum axial strengths of CFT columns additionally confined by CFS are increased higher than those of the current CFT columns, and that local buckling can be delayed due to the confinement effect of CFS.