고립성 직장결핵 3예

이동수,정강욱,황도연,이형화,김대현,김영성,곽동협 대한내과학회 2003 대한내과학회지 Vol.64 No.1

저자들은 장결핵 중 발생 부위상 드문 곳으로 알려진 직장에 발생한 고림성 결핵을 3예 경험하였기에 문헌고찰과 함께 보고하는 바이다. Isolated rectal tuberculosis commonly involves sigmoid, ascending, or transverse colon. Rectal involvement in tuberculosis is uncommon and poorly characterized. Isolated rectal tuberculosis was defined as focal lesions of rectum in the abscence of demonstrable lesions in the small and large bowel. Diagnosis of rectal tuberculosis was based on characteristic endoscopic appearance of lesions, histopathologic feature of tuberculosis in biopsy material and response to antitubercular therapy. Three patients with isolated rectal tuberculosis were seen at Kwak's hospital. The lesions observed was classified according to macroscopic morphology as follows: ulcerative, hypertrophic and ulcero-hypertrophic. Clinical manifestations were non-specific and consists of rectal bleeding, fever, weight loss, constipation and abdominal pain. One of the three patients had coexisting tuberculous pleurisy. Response to antitubercular chemotherapy was good. (Koeran J Med 64:96-100, 2003)

단측 도달법과 양측 도달법을 이용한 경피적 척추 성형술에서 골시멘트 분포 및 누출 비교

이재협 ( Jae Hyup Lee ),윤강섭 ( Kang Sup Yoon ),강승백 ( Seung Baik Kang ),조현철 ( Hyun Chul Jo ),이상기 ( Sang Ki Lee ),장봉순 ( Bong Soon Chang ),이춘기 ( Choon Ki Lee ),이지호 ( Ji Ho Lee ) 대한골절학회 2006 대한골절학회지 Vol.19 No.4

목적: 본 연구의 목적은 척추 성형술에서 단측 도달법과 양측 도달법의 골시멘트 분포양상 및 누출 등 방사선학적 결과를 비교하는 것이다. 대상 및 방법: 2002년 5월부터 2006년 1월까지 본 교실에서 척추 성형술을 시행하고 3개월 이상 추시 가능하였던 100추체 중 단측 도달법 (1군)을 이용한 55추체와 양측 도달법 (2군)을 이용한 45추체에 수술 시간, 주입한 골시멘트 양, 전방 추체 높이 회복, 후만각, 골시멘트의 추체 단면 분포, 골시멘트 누출 등의 결과를 비교하였다. 결과: 수술 시간은 1추체 수술 시 1군이 평균 28분, 2군이 평균 29이있다. 주입한 골시멘트 양은 1군이 3.9 cc, 2군이 5.1 cc로 2군이 유의하게 많았다 (p=0.016). 전방 추체 높이비는 1군이 수술 전 71.8%에 비해 수술 후 3개월째 76.1%였고, 2군이 수술 전 78.3%에서 수술 후 3개월째 77.7%였다. 후만각은 1군이 수술 전 10.7도에서 수술 후 3개월에 11.3도였으며 2군은 수술 전 1.5도에서 수술 후 3개월에 3.6도로 양 군에 유의한 차이는 없었다. 골시멘트 분포는 8개 구역 이상에 분포하는 비율은 2군이 유의하게 (p=0.014) 높았으나 전방 추체 전체나 7개 구역 이상에 분포하는 비율은 유의한 차이가 없었다. 골시멘트 누출은 1군이 25추체 (45.5%)였고 2군이 25추체 (55.6%)로 유의한 차이가 없었다. 결론: 단측 도달법을 이용한 경피적 척추 성형술은 양측 도달법에 비해 주입되는 골시멘트양이 적지만 골시멘트의 추체내 분포나 누출이 양측 도달법과 큰 차이가 없으며 3개월 추시상 방사선학적 지표도 유사하여 골다공증성 추체 골절에 사용할 수 있는 유용한 수술법으로 사료된다. Purpose: To evaluate the differences of radiological outcomes of uniportal and biportal vertebroplasty in the point of bone cement distribution and leakage. Materials and Methods: A retrospective study reviewing the period between May 2002 and January 2006 investigated 100 vertebrae which underwent vertebroplasty and followed for more than three months by uniportal approach (55 vertebrae, group 1) and biportal approach (45 vertebrae, group 2). The operative time, the amount of bone cement injected, anterior vertebral height restoration. kyphotic angle, bone cement distribution, and bone cement leakage were evaluated. Results: The amount of injected bone cement of group 1 (3.9 cc) was statistically smaller than that of group 2 (5.1 cc) (p=0.016). There were no significant differences in the operative time, anterior vertebral height reatoration, kyphotic angle in both groups. The rate of bone cement distribution over 8 zones was significantly higher in group 2 than in group 1(p=0.014). However, the rate of bone cement distribution over 7 zones and the rate of bone cement distributed on whole anterior vertebral body were not significantly different in both groups. The cement leakage was not also significantly different in both groups. Conclusion: Although the amount of injected bone cement was smaller in uniportal vertebroplasty, the radiological results and cement leakage were similar to biportal vertebroplasty. These findings suggest that uniportal vertebroplasty can be the operative options in osteoporotic vertebral fracture.Purpose: To evaluate the differences of radiological outcomes of uniportal and biportal vertebroplasty in the point of bone cement distribution and leakage. Materials and Methods: A retrospective study reviewing the period between May 2002 and January 2006 investigated 100 vertebrae which underwent vertebroplasty and followed for more than three months by uniportal approach (55 vertebrae, group 1) and biportal approach (45 vertebrae, group 2). The operative time, the amount of bone cement injected, anterior vertebral height restoration. kyphotic angle, bone cement distribution, and bone cement leakage were evaluated. Results: The amount of injected bone cement of group 1 (3.9 cc) was statistically smaller than that of group 2 (5.1 cc) (p=0.016). There were no significant differences in the operative time, anterior vertebral height reatoration, kyphotic angle in both groups. The rate of bone cement distribution over 8 zones was significantly higher in group 2 than in group 1 (p=0.014). However, the rate of bone cement distribution over 7 zones and the rate of bone cement distributed on whole anterior vertebral body were not significantly different in both groups. The cement leakage was not also significantly different in both groups. Conclusion: Although the amount of injected bone cement was smaller in uniportal vertebroplasty, the radiological results and cement leakage were similar to biportal vertebroplasty. These findings suggest that uniportal vertebroplasty can be the operative options in osteoporotic vertebral fracture.

승모판 협착증과 동반된 자유롭게 부유하는 좌심방 구형혈전 1례

이정철,김영조,김영진,한승세,이태일,이동협,홍은표,최교원,심봉섭,강승호,신동구,이현우 영남대학교 의과대학 1993 Yeungnam University Journal of Medicine Vol.10 No.1

저자들은 승모판 협착증과 동반된 자유롭고 부유하는 좌심방내의 구형혈전은 1례를 치험하였기에 그 희귀성에 비추어 문헌 고찰과 함께 보고하는바이다. A free-floating ball thrombus in the left atrium is a rare complication of the mitral valvular disease. A 53-year-old man was admitted for pain and paresthesia on both legs. On admission he had auscultatory sign of mitral stenosis and mitral regurgitation, and the roentgenogram of his chest revealed a slight pulmonary venous congestion, enlargement of the pulmonary conus and cardiomegaly. Laboratory findings including complete blood counts, coagulation studies and blood chemistry were normal. An echocardiographic examination revealed a mitral stenosis and a free-floating ball thrombus in the left atrium. We performed the emergent open heat surgery for removal of the ball thrombus and mitral replacement successfully with Duromedics 29 mm valve. The size of thrombus was 39 X 32 X 30 mm.

만성신부전을 동반한 신장의 Oncocytormatosis 1예

이창선,이서진,강지향,이공섭,최현주,홍종서,황보빈,김연수,안규리,한진석,김성권,이정상,이종욱,김승협 대한신장학회 2000 대한신장학회잡지 Vol.19 No.6

Nitric Oxide Donor, NOR-3, Increased Expression of Cyclooxygenase-2, but not of Cyclooxygenase-1 in Cultured VSMC

Lee, Dong-Hyup,Park, Ji-Eun,Kang, Young-Jin,Lee, Kwang-Youn,Choi, Hyoung-Chul The Korean Society of Pharmacology 2006 The Korean Journal of Physiology & Pharmacology Vol.10 No.3

NO and cyclooxygenase-2 (COX-2) are contributes to vascular inflammation induced by various stimulation. The mechanism, which explains a linkage between NO and COX-2, could be of importance in promoting pathophysiological conditions of vessel. We investigated the effects of NO donors on the COX-l and COX-2 mRNA/protein expression, as well as the nitrite production in culture medium of vascular smooth muscle cell (VSMC). VSMC was primarily cultured from thoracic aorta of rat. In this experiments, COX-l and COX-2 mRNA/protein expressions were analysed and nitrite productions were investigated using Griess reagent. VSMC did not express COX-2 protein in basal condition (Nonlipopolysaccharide (LPS) stimulated). In LPS-stimulated experiments, after 3 hours of NO donor pretreatment, LPS $10{\mu}g/ml$ was treated for 24 hours. COX-l protein expressions were unchanged by SNP and NOR-3. NOR-3 significantly increased COX-2 mRNA/protein expression under LPS stimulation. In contrast, SNP did not increase COX-2 mRNA/protein expression under LPS stimulation. Nitrite production was higher in NOR-3 treatment than SNP treatment under LPS stimulation. These results suggest that the expression of COX-2 in VSMC is regulated by NOR-3, COX-2 expressions were depending on the types of NO donor and LPS stimulation in VSMC.

Long-term Follow up of<i>Helicobacter pylori</i>IgG Serology After Eradication and Reinfection Rate of<i>H. pylori</i>in South Korea

Lee, Jung Hoon,Kim, Nayoung,Chung, Jae Il,Kang, Kyung Phil,Lee, Sang Hyup,Park, Young Soo,Hwang, Jin-Hyeok,Kim, Jin-Wook,Jeong, Sook-Hyang,Lee, Dong Ho,Jung, Hyun Chae,Song, In Sung Wiley (Blackwell Publishing) 2008 HELICOBACTER -CAMBRIDGE USA- Vol.13 No.4

<P>BACKGROUND: Serology is widely used for epidemiologic research of Helicobacter pylori. However, there is limited information on the long-term follow up of H. pylori titers after eradication. In addition, it is presumed that the reinfection rate decreases as the H. pylori infection rate decreases. The aim of this study was to investigate the long-term follow up of H. pylori IgG, and to evaluate the reinfection rate of H. pylori in Korea. METHODS: Among 247 patients, who were enrolled during 2003-07, 185 patients with invasive H. pylori test positive received proton pump inhibitor-based triple therapy, and follow-up H. pylori testing, including histology, CLOtest, culture, and serology, were evaluated 2, 10, and 18 months after H. pylori eradication. RESULTS: The initial H. pylori IgG optical density (OD(450 nm)), 2.06, gradually decreased to 0.63 (67% reduction) at 18 months after H. pylori eradication. The seroreversion rate was 5, 10, and 45% at 2, 10, and 18 months after H. pylori eradication, respectively. The recrudescence of H. pylori was 3.49%, and the annual reinfection rate was 2.94% per year. H. pylori IgG titers abruptly increased in cases with recrudescence and reinfection, and correlated with the results of the invasive H. pylori tests. CONCLUSION: The results of this study showed that H. pylori IgG serology could be used for the determination of reinfection of H. pylori, but not for the diagnosis of H. pylori eradication. The reinfection rate of H. pylori, in Korea, was found to be very low, 2.94% per year.</P>

Modification of Optical and Mechanical Surface Properties of Sputter-Deposited Aluminum Thin Films through Ion Implantation

Kang, Tae June,Kim, Jeong-Gil,Lee, Ho-Young,Lee, Jae-Sang,Lee, Jae-Hyung,Hahn, Jun-Hee,Kim, Yong Hyup 한국정밀공학회 2014 International Journal of Precision Engineering and Vol.15 No.5

Aluminum (Al) thin films are used widely as an electronic material in a variety of applications because of their high conductivity, optical reflectance and low cost. In the present study, helium (He) and nitrogen (N2) ions were implanted in sputter-deposited Al thin films with different doses and energies, and the changes in the film properties, such as the surface roughness, optical reflectance, hardness and Young's modulus, were investigated. The results showed that the implantation of both ions smooth the surface of Al thin films by decreasing the hillock density, resulting in low global surface roughness. In particular, in the case of He ion implantation, the moderated degradation of optical reflectance was observed compared to the film implanted with nitrogen ion. On the other hand, excessive ion implantation increased the local (short-range) surface roughness, which deteriorated the optical reflectance of the Al films. The continuous stiffness measurement technique in nano-indentation showed that ion implantation increased the hardness near the surface. He ion implantation hardened the surface of the Al thin film, and almost 2 times higher surface hardness was achieved with an ion dose of $10^{18}ions/cm^2$ at 40 KeV.

Aprotinin Inhibits Vascular Smooth Muscle Cell Inflammation and Proliferation via Induction of HO-1

Lee, Dong-Hyup,Choi, Hyoung-Chul,Lee, Kwang-Youn,Kang, Young-Jin The Korean Society of Pharmacology 2009 The Korean Journal of Physiology & Pharmacology Vol.13 No.2

Aprotinin is used clinically in cardiopulmonary bypass surgery to reduce transfusion requirements and the inflammatory response. The mechanism of action for the anti-inflammatory effects of aprotinin is still unclear. We examined our hypothesis whether inhibitory effects of aprotinin on cytokine-induced inducible nitric oxide synthase (iNOS) expression (IL-$l\beta$ plus TNF-$\alpha$), reactive oxygen species (ROS) generation, and vascular smooth muscle cell (VSMC) proliferation were due to HO-l induction in rat VSMCs. Aprotinin induced HO-l protein expression in a dose-dependent manner, which was potentiated during inflammatory condition. Aprotinin reduced cytokine mixture (CM)-induced iNOS expression in a dose dependent manner. Furthermore, aprotinin reduced CM-induced ROS generation, cell proliferation, and phosphorylation of JNK but not of P38 and ERK1/2 kinases. Aprotinin effects were reversed by pre-treatment with the HO-l inhibitor, tin protoporphyrin IX (SnPPIX). HO-l is therefore closely involved in inflammatory-stimulated VSMC proliferation through the regulation of ROS generation and JNK phosphorylation. Our results suggest a new molecular basis for aprotinin anti-inflammatory properties.

차별화 서비스에서 종단간 QoS 보장을 위한 대역 브로커 설계 및 구현

이강원(Kang-Won Lee),박기현(Ki-Hyun Park),최영수(Young-Soo Choi),이성협(Sung-Hyup Lee),조유제(You-Ze Cho),한태만(Tae-Man Han) 한국통신학회 2004 한국통신학회 학술대회 및 강연회 Vol.2004 No.4

Monitoring Application Traffic through Dynamic Circuit Network

Min-Hyup Kang,Moo-Sam Kang,Wang-Cheol Song,Jae-Hwa Lee 한국콘텐츠학회 2010 ICCC International Digital Design Invitation Exhib Vol.2010 No.12