우리나라 상차림의 영양적 평가

김영순,이정희,오순덕,김수현,이정민,남택수,박태식,천유정 高麗大學校 倂設 保健大學 保健科學硏究所 2002 保健科學論集 Vol.28 No.1

This study was carried out to investigate the current nutritional problems owing to the increased consumption of westernized food in Korea and also was conducted to compare the nutritional characteristics of Korean traditional meal with those of the Western diet in similar serving size. The results obtained from nutritional evaluation are as follows: 1. The percentage of calories represented by carbohydrate: lipid: protein was 65:15:20 respectively for Korean traditional meal (Table setting of 3 Chop) therefore these ratios meet the dietary recommended allowances for Koreans. 2. Nutrient values of Korean traditional 3-Chop were shown to be better balanced than those of Western diet when the nutrients of the two types of diet were estimated by similar serving sizes and calories. 3. Compared to the Korean traditional meal, most fast foods were nutritionally imbalanced especially in that most of them showed higher amounts of fats. These results show that Korean traditional meals supply ideal nutrient intakes in contrasts to the westernized diet, therefore much work remains in developing a variety of menus and standard recipes for Korean traditional meals according to the changes in diet trends as well as emphasing the importance of Korean traditional meals as part of an ideal, well-banlanced diet.

Negative Regulation of Hypoxic Responses via Induced Reptin Methylation

Jason S. Lee,김윤호,김익수,김보규,최희준,이지민,신희재,김정화,김지영,서상범,이호,Olivier Binda,Or Gozani,Gregg L. Semenza,김민형,김근일,황대희,백성희 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

Negative Regulation of Hypoxic Responses via Induced Reptin Methylation

Jason S. Lee,김윤호,김익수,김보규,최희준,이지민,신희재,김정화,김지영,서상범,이호,Olivier Binda,Or Gozani,Gregg L. Semenza,김민형,김근일,황대희,백성희 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

Loss of EMP2 Inhibits Melanogenesis of MNT1 Melanoma Cells via Regulation of TRP-2

Enkhtaivan Enkhmend,Kim Hyun Ji,Kim Boram,Byun Hyung Jung,Yu Lu,Nguyen Tuan Minh,Nguyen Thi Ha,Do Phuong Anh,Kim Eun Ji,Kim Kyung Sung,Huy Hiệu Phùng,Rahman Mostafizur,Jang Ji Yun,Rho Seung Bae,이호,Kan 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.2

Melanogenesis is the production of melanin from tyrosine by a series of enzyme-catalyzed reactions, in which tyrosinase and DOPA oxidase play key roles. The melanin content in the skin determines skin pigmentation. Abnormalities in skin pigmentation lead to various skin pigmentation disorders. Recent research has shown that the expression of EMP2 is much lower in melanoma than in normal melanocytes, but its role in melanogenesis has not yet been elucidated. Therefore, we investigated the role of EMP2 in the melanogenesis of MNT1 human melanoma cells. We examined TRP-1, TRP-2, and TYR expression levels during melanogenesis in MNT1 melanoma cells by gene silencing of EMP2. Western blot and RT-PCR results confirmed that the expression levels of TYR and TRP-2 were decreased when EMP2 expression was knocked down by EMP2 siRNA in MNT1 cells, and these changes were reversed when EMP2 was overexpressed. We verified the EMP2 gene was knocked out of the cell line (EMP2 CRISPR/Cas9) by using a CRISPR/Cas9 system and found that the expression levels of TRP-2 and TYR were significantly lower in the EMP2 CRISPR/Cas9 cell lines. Loss of EMP2 also reduced migration and invasion of MNT1 melanoma cells. In addition, the melanosome transfer from the melanocytes to keratinocytes in the EMP2 KO cells cocultured with keratinocytes was reduced compared to the cells in the control coculture group. In conclusion, these results suggest that EMP2 is involved in melanogenesis via the regulation of TRP-2 expression.

PRR16/Largen Induces Epithelial-Mesenchymal Transition through the Interaction with ABI2 Leading to the Activation of ABL1 Kinase

( Gyeoung Jin Kang ),( Jung Ho Park ),( Hyun Ji Kim ),( Eun Ji Kim ),( Boram Kim ),( Hyun Jung Byun ),( Lu Yu ),( Tuan Minh Nguyen ),( Thi Ha Nguyen ),( Kyung Sung Kim ),( Hiệu Phùng Huy ),( Mostafizu 한국응용약물학회 2022 Biomolecules & Therapeutics(구 응용약물학회지) Vol.30 No.4

Advanced or metastatic breast cancer affects multiple organs and is a leading cause of cancer-related death. Cancer metastasis is associated with epithelial-mesenchymal metastasis (EMT). However, the specific signals that induce and regulate EMT in carcinoma cells remain unclear. PRR16/Largen is a cell size regulator that is independent of mTOR and Hippo signalling pathways. However, little is known about the role PRR16 plays in the EMT process. We found that the expression of PRR16 was increased in mesenchymal breast cancer cell lines. PRR16 overexpression induced EMT in MCF7 breast cancer cells and enhances migration and invasion. To determine how PRR16 induces EMT, the binding proteins for PRR16 were screened, revealing that PRR16 binds to Abl interactor 2 (ABI2). We then investigated whether ABI2 is involved in EMT. Gene silencing of ABI2 induces EMT, leading to enhanced migration and invasion. ABI2 is a gene that codes for a protein that interacts with ABL proto-oncogene 1 (ABL1) kinase. Therefore, we investigated whether the change in ABI2 expression affected the activation of ABL1 kinase. The knockdown of ABI2 and PRR16 overexpression increased the phosphorylation of Y412 in ABL1 kinase. Our results suggest that PRR16 may be involved in EMT by binding to ABI2 and interfering with its inhibition of ABL1 kinase. This indicates that ABL1 kinase inhibitors may be potential therapeutic agents for the treatment of PRR16-related breast cancer.

원격탐사를 위한 병렬계산 기법

김형중,장태정,김희원,김형수,이정문,장순자 강원대학교 석재복합신소재제품연구센터 1996 석재연 논문집 Vol.1 No.-

원격탐사에 사용되는 편미분방정식을 고속으로 풀기 위한 기법을 프로그래밍하고 성능을 향상시킬 수 있는 방법을 제시했다. 미지수가 30만개 이상되는 복소수(non-Hermitian) 행렬의 해를 구하는 프로그램을 작성했다. 이 프로그램은 C와 PVM에 기반을 두고 있다. 수렴속도를 향상시키기 위해 대각 스케일링을 이용했다. 통신속도의 개선을 위해 데이터 압축 기법을 이용했다. 수렴속도를 측정 제시함으로써 실제 문제 적용에 참고할 수 있다. Network-based computing with cluster of personal computers or workstations recently has become an important and successful technique. Network-based computing enables fast computation and resolves short of storage with computers on the desks. Cluster of inexpensive computers offers them aggregated computing power and storage to challenge very large-scale problems. Iterative solvers are used for the large sparse linear systems. Preconditioners accelerate the rate of convergence of the iterative solvers. However, parallelization accelerate the rate of convergence of the iterative solvers. However, parallelization of preconditioners is far from satisfaction so far. Thus, the simplest diagonal scaling is a good alternative for improved convergence and easy parallelization. In order to reduce communication overhead, a data compression technique is considered. Data communication time can be reduced at the cost of convergence rate. MATLAB simulation result is given in this paper. This method is effective to cluster of computers connected through slow networks.

老年期女性의 背面彎曲度 減少效果를 爲한 衣服디자인 硏究

金泰京,李京姬,朴正順 한국의류학회 1990 한국의류학회지 Vol.14 No.3

The author has studied the effect of clothes design to mask the dorsal curvature that is one of the commonest changes in elderly women. Body measurements including the body type and the status of dorsal curvature were performed on 153 women of over 60 years of age, and then a body form to fit to the mean measurements was made to evaluate the effects of various designs to it. With 31 pattern designs modified by changing in their slash lines and gathers using darts, the diminishing effect of the rounded back were evaluated by means of sensory test. The results of this study can be summarized as follows: I. Results from the body measurements 1) The mean body type in elderly women was that of obesity. 2) With the advancement of age, the angle to indicate the degree of dorsal curvature as well as the angle to indicate the posture are increased. II. Concerning to the clothes design to diminish the shape of dorsal curvature 1) Among the designs by the position of darts, the basic pattern (Fig. 5-1-①) showed the best effect to mask the shape of dorsal curvature. 2) Out of the applied designs of princess lines, that in which the slash line is pointing toward the shoulder point (Fig. 5-2-①) seemed to be most effective. 3) What has angled princess line (Fig. 5-3-①) had the most diminishing effect among the waist darts and armhole princess lines. 4) Among the V-shaped designs, the slashed at the shoulder point (Fig. 5-4-①) had the best effect to lessen the shape of the dorsal curvature. 5) Wider angle yoke had better effect to the narrow angle one among the designs with straight yoke, and that with downward direction (Fig. 5-5-①) showed the best effect. 6) Between straight wide angle yoke and curved yoke, that of curved one with downward direction (Fig. 5-6-①) had better effect as far as the masking effect of dorsal curvature is concerned. 7) Gathers around the neck showed better effect to those around the shoulder, and the more amount of gathers (Fig. 5-7-①), there was better effect. 8) The design with midline gathers at the level of horizontal slash line of armhole (Fig. 5-8-①) showed better effect to that with seperated gathers. 9) In case of design with gathers at the horizontal line of armhole, it showed the better effect with less amount of gathers in midline ones, but with more amount in the side ones. 10) Considering all 7 different designs with better effect in covering the shape of dorsal curvature, it was evident that the design with gathers was far better than the design with application of slash lines.

Staphylococcus lugdunensis에 의해 생산되는 δ-Like haemolysin

김성수,김정희 圓光大學校 齒科大學 學生會 1995 學生學術誌 Vol.2 No.1

Staphylococcus aureus, regarded as the most pathogenic species, produces four haem olysins (α, β, r,δ) but Staphylococcus lugdunensis only produces δ-like haemolysin. This experiment is desinged for revealing the difference between S. aureus and S. lu gdunensis with restriction endonuclease analysis of DNA. Hind III was used for restriction endonuclease and the difference between haemolysin producing S. lugdunensis and non-producing S. lugdunensis was also revealed. Therefore restriction endonuclease analysis of DNA might be used to diagnosis of inf ectious disease.

현대복식에 나타난 그라피티(Graffiti)기법에 관한 연구

金朱榮,李政侯,楊淑喜 복식문화학회 1997 服飾文化硏究 Vol.5 No.3

The purpose of thins paper is to investigate the relation between Graffiti techniques and the contemporary dress. Graffiti is the internal expression of human potential desires which is composed of informative signs. As Graffiti have become the cross-cultural condition under the Hiphop culture, it makes the meaningless space into the characteristic space, and proposes the identities of graffiti 'writers'. In the contemporary dress, Graffiti look has become means of communication and playfulness. Through the external forms like icon, index, and symbol, graffiti look expresses individual, social, and political identities, and the aesthetic values of satirement and playfulness. It would be define graffiti look as postmodern characteristics, as it were, which has collapsed between the mainstream and anti-mainstream, and it contributes to spread streetstyle to catwalk.

동서양의 식용꽃에 대한 고찰 : 조리방법을 중심으로

김영순,이정희,오순덕,정은미,최지영,유은순,장정미,정진선,하상민 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.2

Edible flower means a flower that is good to eat is subject to either cooking or appetizing. In general, people eat edible flower as raw so that the loss of vitamin and inorganic are minimal. Edible flower is usually utilized as salad material or aromatic, decoration for jelly or cake and solid stuff in soup. Thus, decorating food by edible flower improves flavor, fragrance and appetite. Edible flower serves various purposes both east and west. In Korea, Edible flower is mainly subject to soup, cooked potherbs, frying, tea stuff, brewing and etc, whereas in Japan, its various usage covers cooked potherbs, pickle, sliced raw fish, frying, salad, jelly and decoration. On the other hand, Edible flower is used as numerous salad and tea stuff, condiment, roasting, meat, sweets and desserts in Western Hemisphere.