방광 자극증상을 호소하는 복압성 요실금 환자에서 마이크로칩을 이용한 전기자극치료의 효과

정희창,정연호,신현진 영남대학교 의과대학 2004 Yeungnam University Journal of Medicine Vol.21 No.2

복압성 요실금에 동반되는 다양한 방광 자극증상은 빈뇨, 잔뇨감, 야간뇨, 절박뇨, 절박성 요실금, 배뇨통의 순이었으며, 이 증상들의 복합 정도가 많으면 삶의 질에 영향을 주고 있음을 알 수 있었다. 그리고 마이크로칩을 이용한 전기자극기는 특별한 부작용 없이 환자의 만족도가 높은 치료기로 생각되었으며, 복압성 요실금과 동반되는 야간뇨, 배뇨통 등의 방광 자극증상을 경감시킴으로 인해 현재의 배뇨 상태가 일상생활에 미치는 영향을 감소시키는 것을 관찰할 수 있었다. Purpose: This study was carried out to evaluate the efficacy of intravaginal pelvic floor electrical stimulation (FES) therapy on bladder irritability symptoms in stress urinary incontinent women. Materials and Methods: The evaluation before and after treatment included the Blaivas's female Bladder Questionnaire, the quality of life questionnaires and the overall satisfaction with present voiding state using visual analogue test (VAT). All patient were treated for 20 minutes, twice a week for 6 weeks, using a new intravaginal electrical stimulator with microchip (PIC16C74). Results: After the FES therapy, the overall success rate of the SUI was 50.4.% at 9 months. The bladder irritability symptoms such as frequency, nocturia, urgency, residual urine sensation and lower abdominal discomfort were improved. In particular, the symptoms of frequency, urge incontinence, dysuria were significantly improved after the FES therapy at 9 months. The VAT score of the overall satisfaction with the present voiding state was significantly lower after the FES therapy. 73.7% of patients were satisfied with the FES therapy and complications such as hemorrhage, vaginitis' urinary tract infection and pain were not encountered. Conclusion: These results suggest that FES therapy with microchip improves some bladder irritability in SUI women. Therefore, electrical stimulation therapy should be considered as a first line therapy in SUI women with bladder irritability symptoms.

불악산(경기도)의 식물상에 관한 연구

안영희,안영철,최광율,박대식,정연택 중앙대학교 유전공학연구소 2001 遺傳工學硏究論集 Vol.13 No.1

Field surveys were carried out 3 times from 2000 5. 17 to 2000. 6. 4. Main results obtained from this study wet·e as follows : 1.The vascular Plants in Mt. Bull-ak were consisted of 221 taxa such as 71 families, 163 genera, 188 species, 30 varieties, 2 forma, 1 hybrid. 2.Family Compositae and Gramineae covers 8.6% and 7.2% of total number of naturalized plants, respectively. 3.Pteridophyte, Gymnosperm, Dicotyledon and Monocotyledon covers 2.5%, 2.7%, 75.9% and 18.1% of total number of naturalized plants, respectively. 4.The life cycle of the plants was annual 11.8%, biennial 11.3%, perennial 76.9%. As it compared with consistency ratio in the flora of Korea, the distribution of biennial appeared highly. 5.The highest peak of blooming month is May (49.3% among total number of naturalized plants). 6.In this area the Korean endemic plants are 5 taxa (2.3% among total number of naturalized plants). 7.Number of naturalized is 20 taxa (9.0% among total number of naturalized plant)

建築物 構成部材의 材料特性에 따른 2次元 熱傳導解析 硏究

추연희,김화중 대한건축학회 2003 대한건축학회논문집 Vol.19 No.2

Thermal Analysis with material characteristics is a part of performance based design for fire-resistance and is base of structural response for elements in buildings. To predict thermal response of elements in buildings, we developed the 2D Thermal Conduction Analysis System for the constitutive elements with C language in this study. Also, the tool for thermal analysis is constructed to be able to do the multi-tasking e.g treating input & output data, and running program for the user's convenience with visual basic 6.0. To prove the correctness of the result through the numerical analysis, we took the thermal analysis data from the surface of steel exposed to the high temperature over 800℃ in reference and we ran the TCA program under the same conditions of data in reference. Also we verified the applications of Thermal Analysis System to many kinds of materials e.g., brick, CFT, concrete elements.

갑상샘암 수술환자의 심리 및 신체적 불편감에 미치는 정보교육 프로그램 효과

이양희,정영,박연주,최길순,정지연 朝鮮大學校 附設 醫學硏究所 2008 The Medical Journal of Chosun University Vol.33 No.2

본 연구는 정보교육 프로그램이 갑상샘암 수술 환자의 심리 및 신체적 불편감 감소에 미치는 효과를 검정하기 위해 실시된 비동등성 대조군 전,후 시차 설계의 유사 실험연구이다. 자료수집 기간은 2006년 6월 17일 부터 9월 19일 까지 3개월간 이었으며, 연구 대상자는 일개 종합병원에 갑상샘암 수술을 받기위해 입원한 환자 가운데 6월 17일 부터 8월 3일 까지 입원환자 29명을 대조군으로 하였고, 8월 5일 부터 9월 19일 까지 입원환자 30명을 실험군으로 하였다. 연구도구는 심리적 불편감을 측정하기 위해 Derogatis 등(14)이 개발한 ‘자기보고식 다차원 증상목록(Multidimensional Symptom Inven- tory)검사를 사용하였고, 신체적 불편감 측정은 McCorkle & Young(16)이 개발한 도구를 사용하였다. 본 연구의 결과는 다음과 같다; 1) 정보교육 프로그램을 받은 실험군은 정보교육 프로그램을 받지 않은 대조군에 비해 심리적 불편감 정도의 차이는 통계적으로 유의한 차이를 보이지 않았다(p= .135). 다만 ‘근심 걱정’요인에서 유의한 불편감 감소효과를 보였다(p= 0.49) . 2) 정보교육 프로그램을 받은 실험군과 정보교육 프로그램을 받지 않은 대조군은 두군 모두 신체적 불편감 정도가 사후 유의한 수준으로 증가함을 보였다(p= 0.90). 결론적으로 본 연구를 위해 만들어진 정보교육 프로그램은 갑상샘암 수술 환자의 신체적 불편감 감소에는 효과적이지 못하였으나 심리적 불편감의 근심걱정 요인을 감소시키는데는 효과가 있음을 알게 되었다. Objectives: This study was designed as a non-equivalent control group pre and post-test quasi-experimental study to examine the effects of education program using information on the psychological and physical discomfort of patients undergoing operation for cancerous thyroid glands. Methods: The study covered for three months from June 17, 2006 to September 19, 2006. The subjects of this study were selected from those patients who were admitted in one of the general hospitals in order to receive the operation for cancerous thyroid glands. They include 29 control group patients who were hospitalized during the period of Jun 17th to August 3rd 2006, and 31 experimental group patients who were hospitalized during the period of August 5th to September 19th, 2006, respectively. The instruments utilized for conducting this study includes the Multidimensional Self-Report Symptom Inventory test originally developed by Derogatis & et al. (1983) for measuring psychological discomfort. And for measuring physical discomfort, the tools developed by McCorkle & Young (1978) was utilized. Results: 1) Hypothesis 1 “The level of psychological discomfort of the experimental group who completed the information education program would be decreased comparing with that of the control group who didn't complete the program” was partly supported (Worry & Anxiety factor: p= .049). 2) Hypothesis 2 “The level of physical discomfort of the experimental group who completed the information education program would be reduced comparing with that of the control group who didn't complete the program” was not supported (p= -.90). Conclusion: The information program provided for this study was proved to be not effective for decrease physical discomfort of the patients undergoing operations for cancerous thyroid glands but proved to be effective for decrease the anxiety factor of psychological discomfort.

중추신경계에서의 효모 가수분해물이 음식섭취조절기전에 미치는 영향

이승언,정경희,김미자,배윤정,장은재 동덕여자대학교 2004 생활과학연구 Vol.9 No.-

Saccharomyces cerevisiea, which has been known as antistress compounds, was hydrolyzed by proteinase producing SCP-20. The addition effects of SCP-20 on the food intake regulation mechanism were studied measuring the expression amount of neurotransmitters, such as NPY and NOS, which can increase food intake in hypothalamus, and CCK, which can decrease food intake by using immunohistochemistry method. The 0, 2, and 5 g/kg SCP-20 was orally administrated to the experimental animals for one week. The expression of NPY and NOS was increased in the group of 5 g/kg administrated animals while that of CCK was increased in the group of 2 g/kg administrated animals. The results of this study suggested that SCP-20 may influence the control mechanism of oral dose-dependently. Further studies are needed to elucidate the roles of SCP-20 on the changes of food intake regulation controlling neurotransmitters.

Hydroxycitrate, Carnitine 및 Capsaicin을 함유한 식이 보조제(3D-Relax Diet)의 체중 감량 효과

정은영,정경희,김미자,배윤정,장은재 동덕여자대학교 2004 생활과학연구 Vol.9 No.-

The aim of this study was to evaluate the effects of 3D-Relax Diet; a proprietary formation containing hydroxycitrate(233mg/g), carnitine(150mg/g); and capsaicin (150mg/g); on body weight, % body fat, fat mass, lean body mass, Resting Metabolic Rate(RMR), body circumference, skinfold thickness, serum glucose and lipid level. Nineteen female college students participated in this 4 weeks weight control program. All subjects were randomly assigned to the Sang sik(S) group or Sang sik & 3D-Relax(3D) group. Mean energy intake of 3D group was l,523.1±300.2 ㎉(carbohydrate: 66.3%, protein: 18.7%, fat: 15.0%) and S group consumed 1,464.8±142.1 ㎉(carbohydrate: 65.1%, protein: 19.0%, fat: 15.9%) during program. The 3D group lost 3.1±1.3 kg of body weight, 2.5±l.4 kg of fat mass, 0.6±1.2 kg of lean body mass and 16.8±183.3 ㎉/d of RMR and the S group lost 1.8±1.0 kg of body weight, 1.1±1.1 kg of fat mass, 0.8±0.3 kg of lean body mass and 19.1±181.9 ㎉/d of RMR. There was no significant differences in the loss of lean body mass and RMR between two groups, however, the total body weight and the fat mass were significantly decreased in the 3D group compared to the S group(p<0.05). The 3D group experienced a significant reduced hip size, total-cholesterol and HDL-cholesterol, however, the change of these between groups were not significantly different. There were no differences in the change of body circumference, skinfold thickness, serum glucose and lipid. These results suggest that the intake of 3D-Relax Diet(hydroxycitrate, carnitine, and capsaicin) during the weight control program decreased energy intake, fat intake and total body weight especially fat mass and those effects are presumably linked to the prevention of RMR decline and the inhibitory effects on lipogenesis.

뇌사환자의 갑상선 기능, 전신대사 및 중증도에 관한 연구

이영주,정금희,왕희정,문봉기,한연희,이영석 아주대학교 의과학연구소 1999 아주의학 Vol.4 No.1

Background and Objectives : Brain death may lead to hormonal depletion, metabolic derangement and multiple organ dysfunction. We have carried out present study to examine the effects of brain death on the thyroid function, metabolic indices, and the severity scoring systems. Methods : 13 adults patients admitted for organ donation or brain death evaluation were examined after brain death was confirmed. Thyroid hormones measured were .thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), and free thyroxine (FT4). The metabolic indices measured were arterial ketone body ratio (AKBR), lactic acid (LA), and base defiat (BD). as for reference to the severity scoring systems, APACHE Ⅲ and multiple organ failure score (MOFS) were assessed on the day of brain death confirmation. Arterial blood was drawn for all measurements. Results : As for the thyroid function, there were significant decreases in T3 (40.48±20.96 ng/dL) and T4 (3.47±2.15 ㎍/dL), but no significant change in FT4 (0.75±0.31 ng/dL) and TSH (1.12±1.37 uIU/mL) compared to the normal range. Significant decreases in AKBR (0.39±0.31) and BD (-9.46±5.83 m㏖/L), and significant increase in LA (2.57±2.46 m㏖/L) In metabolic indices, were shown, as for severity scoring systems, APACHE Ⅲ score (101.54±19.41) and MOF score (9.11±2.57) indicated a high mortality. There were significant correlation between thyroid hormones (r=0.565 -0.781) but no correlation among other indices. Also, significant inverse correlations were shown between base deficit and lactic acid (r=-0.660), APACHE Ⅲ score (r=-0.726) and MOF score (r=-0.604). The highest correlation was observed between APACHE Ⅲ score and MOF score (r=0.851). Conclusions : As for the thyroid function, significant decrease in T3 and T4, and almost normal range of FT4 and TSH imply the euthyroid sick syndrome. Abnormal finding of the metabolic parameters indicates an inhibition of the aerobic metabolic rate of the body as a whole. And the severity scoring parameters are compatible with high mortality.

전류 비유 모델에 의한 초등학생의 전류 개념 변화 분석

유병길,강인석,김병철,남만희,박선희,소하연,윤희정,이영아,이하룡,전병문,정승호 부산교육대학교 과학교육연구소 2000 科學敎育硏究 Vol.25 No.-

There exists a major impediment to learning electricity which may illuminate why direct presentation of scientists' ideas is too aggressive a strategy. This impediment lies in thinking that electricity is used up and in envisaging the light bulb as a consumer. This view is based on a powerful idea which summarises much of our experience; it declares that 'things get used up', 'you cannot get something for nothing', and 'intuitive thinking'. To replace this view with scientific view, we made the analogy model. It is suggested that the analogy model is more effective in teaching electricity circuits than conventional teaching method.

CASE REPORT : Pulmonary Langerhans Cell Histiocytosis in an Adult Male Presenting with Central Diabetes Insipidus and Diabetes Mellitus: A Case Report

( Yeun Seoung Choi ),( Jung Soo Lim ),( Woocheol Kwon ),( Soon Hee Jung ),( Il Hwan Park ),( Myoung Kyu Lee ),( Won Yeon Lee ),( Suk Joong Yong ),( Seok Jeong Lee ),( Ye Ryung Jung ),( Jiwon Choi ),( 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4

Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.

Pulmonary Langerhans Cell Histiocytosis in an Adult Male Presenting with Central Diabetes Insipidus and Diabetes Mellitus: A Case Report

Choi, Yeun Seoung,Lim, Jung Soo,Kwon, Woocheol,Jung, Soon-Hee,Park, Il Hwan,Lee, Myoung Kyu,Lee, Won Yeon,Yong, Suk Joong,Lee, Seok Jeong,Jung, Ye-Ryung,Choi, Jiwon,Choi, Ji Sun,Jeong, Joon Taek,Yoo, The Korean Academy of Tuberculosis and Respiratory 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4

Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.