외부 프리스트레스 도입에 의한 노후된 콘크리트 거더교의 보강성능평가

박승범,홍석주,이봉춘,장석호,권혁준 충남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.15 No.1

One of the promising methods to enhance the flexural strength of a externally prestressed girder is to place the tendons with large eccentricities. The analysis and design of composite girders prestressed by external tendons involve difficulties related mainly to the position of anchorages and the construction sequences. This study was conducted on the concrete bridges reinforced by the continuous girders and the external prestressing. The test results in this study showed that the external prestressing of a composite girder increased the range of the elastic behavior, reduced deflections, increased ultimate strength, and added to the redundancy by providing the multiple stress paths.

南北 詩文學 比較 硏究 : Centered on Poems of 1980's 80년대 詩를 중심으로

朴喆石 東亞大學校 1993 東亞論叢 Vol.30 No.1

Centering on North Korean Gi-Ga in 1980's, I hgave studied generally heterogenity beteen South Korean poems and North Koerens' in many aspects. North Korean Si-Ga has differences in many aspect with South Korean poems in characteristics of genres, figure of expression, themes, and matrials. This is due to the fact that North Korean Si-Ga should be made by the strict policy of literature and art following the nation and the party with difference from South Korean poems that have scarcely factors to be limited. Consequenlty North Korean Si-Ga has been being written by writing order of subjective theory of literature and art, based on characteristics of party, of class, and of the people. This differentiating South Korean poems and North Korean that seperation between south and north for nearly 40 years incur cannot be easily overcome. But the possibility of overcoming it from the standpoint of us wishing united literature should not be given up in advance. The fortunate thing is that a possibility of overcoming can be found in both changes of South Korean poems and North Koreans'. Reality of South Korean Public poetry or Labour poetry and expansion of lyricism in North Korean Si-Ga in 1980's, must contantly support the possibility of approch of both poems to each other.

소각장 환경영향평가시 수은 배출 계수에 관한 연구

전미경,박석순 이화여자대학교 환경문제연구소 1998 이화환경연구 Vol.2 No.-

The amount of mercury emitted from an incinerator depends on the properties of waste, combustion condition, and control devices. Mercury concentration in air proportionates to the increase of incinerator installation. The purpose of this study is to provide a method for determination of mercury emission factor which can predict the amount of mercury emitted from each incinerator specifically. Case study was performed for N municipal waste incinerator. Based on the method presented in this paper, we obtained mercury emission factor as 1.85∼1.95g Hg/t at N Municipal waste Incinerator and this result was regarded as reasonable when compared with existing mercury emission factor in reference cases. Fluorescent lamps turned out to be the most important source(44.4%) of mercury in municipal waste and its amount will tend to increase, while batteries less significants. In additions, medical waste is one of the major source of mercury.

교원 근무성적 평정제도 개선에 관한 연구

박천순,신현석 고려대학교 교육문제연구소 1996 敎育問題硏究 Vol.8 No.-

콘크리트 교량 및 강교의 상시감시 시스템에 관한 연구(Ⅰ)

박승범,홍석주,이봉춘 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.1

The construction of large scale civil and building structures which form the base of social economy has been grown greatly. As the increasing of aged and deteriorated structure, it is necessary to evaluate the safety of those structures. The deterioration, safety evaluation repair and rehabilitation are important problems in the construction area that every country faces. This paper presents the general information on how to conduct a data analysis of long-term monitoring system and evaluate the characteristics of surveying methods.

고온고습으로 저장된 백미의 이화학적 및 취반 특성

박석규,전순실,박미연 순천대학교 기초과학연구소 1994 基礎科學硏究誌 Vol.5 No.-

The quality difference of milled rice stored at a low temperature and optimum humidity(LTH) and a high temperature and humidity (HTH) was determined by the methods of acidity of fat, brown color index, reducing sugar and microflora. Moisture contents of milled rice stored at LTH and HTH for 10 weeks were 14.7% and 19.5%, respectively. Moisture content after 8 weeks of LTH and 4 weeks of HTH exceeded 13% on dry basis, growth-limiting moisture of mold. Brown color index and reducing sugar contents of milled rice stored at HTH were slightly higher than those of LTH. There was a notable difference in acidity of fat between milled and brown rice stored at HTH. The apperance(p<0.05) and texture(p<0.01) of cooked rice after storage for 10 weeks at LTH and HTH were significantly different in sensory evaluation with no significant difference in odor and taste. Mean values of breaking test in rheometer were better in LTH than in HTH for taste score. Growth of mold and bacteria in rice were not increased by storage. Rice weevil exhibited imago in brown rice and milled rice after storage of 5 weeks and HTH. Milled rice stored at LTH for 2 weeks did not absorb Kimchi odor from refrigerated chamber.

두부 외상 환자의 고혈당과 예후와의 상관관계

현석천,이종안,박준석,박상문,김갑득,장인성,김승열,송화식 대한응급의학회 1996 대한응급의학회지 Vol.7 No.2

Severe head injury is associated with a stress response that includes hyperglycemia, which has been shown to worse outcome during cerebral ischemia. To better define the relationship between head injury and hyperglycemia, admission glucose level were analyzed in 150 head injured patients from January 1995 to December 1995. Our retrospective study demonstrated a higher glucose level in patients with low Glasgow Coma Scale(GCS) score, especially at 3-5 GCS score, compared to those with high GCS scores. Also a higher glucose level was noted in patients with vegetative state and dead than in those with good recovery and moderate disability. Hyperglycemia(serum glucose level≥200mg%) was associated with decreased level of consciousness and a poor outcome. We conclude that admission hyperglycemia is a significant indicator of severity of injury(p<0.001), but not significant predictor outcome from head injury. After controlling for the influence of the GCS score, glucose levels do not have an independent effect on outcome.

주변 토지이용을 고려한 농촌마을 소하천 표준 단면 설계 : 농촌 주민의 하천 이용 형태를 중심으로

이춘석,박명안 진주산업대학교 건설기술연구소 1998 건설기술연구소보 Vol.1 No.-

The purpose of this study was to propose standard designs for the ecological improvement of rural streams. According to the survey about ecological conditions of rural streams of 10 rural villages (sept., 1996), the streams could be classified into three divisions(upstream, inner village, downstream), and the average width of streams was 9m, and the height of banks 3.1m. The slopes of basin were 7.33%, 2.67%, 1.39% at upstream, inner village, downstream respectively. The survey about the residents' usage of stream and the preferred activities(June, 1997) showed that the streams were most frequently used for the supply of agricultural water(39%) and for the washing(15%) and for the recreation and rippling(10%), etc.. First of all, three standard plans were designed presenting upstream, inner villages, and downstream, and then three standard sections were made based on each plan. Upstream was designed to be used for the recreational activities in summer and the major stream bank materials were base rock and existing boulders with the least artificiality. As the streams in the residential area were expected to be used and visible frequently, the most facilities for the streamside activity such as waterfront, water holes, shallows, water levels, walk, etc. were concentrated in this part with some artificiality. The downstream were designed for the agricultural use such as water supply, preparation of work and some break during the work.

유산균(L.lactis CBT-8)및 발효 추출물의 Helicobacter pylori 억제 능력

진춘조,박형석,이혜운,김성렬,강동구,이준상,이재동,왕준호 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

Helicobacter pylori infection was the cause of chronic gastritis, duodenal ulcer and gastric MALT lymphoma. The eradication rates of H. pylori using antibiotics are around 80%. Lactobacilli have been demonstrated to have in vivo and in vitro inhibitory effects on H. pylori infection. We aimed to evaluate the inhibitory effect of L. lactis CBT-8 and its extract on H. pylori in human stomach. Thirty-five H. pylori-infected volunteers(30-49 yr)were randomized into two groups which were treated with L. lactis CBT-8 and its extract(Group A n=17) or milk containing L. lactis CBT-8(Group B, n=18). They underwent 13C-urea breath tests before and after treatment. The DOB30 of group A(n=14) was decreased 41.0% after treatment(26.0±4.9 before, 15.3±2.1 after treatment)(p<0.05). the DOB30 of group B(n=13) was decreased 22.3% after treatment(22.0±2.2 before, 17.1±1.7 after treatment)(p<0.05). In conclusion, L. lactis CBT-8 was effective in suppressing H. pylori infection in human stomach.

성인 급성 림프구성백혈병 고위험군에서 일차관해시 동종 및 자가 조혈모세포이식의 성적 비교 : 단일기관 치료경험 A Single Center Experience

이석,민우성,민창기,김동욱,이종욱,김유진,박은정,박윤희,김춘추 대한조혈모세포이식학회 2000 대한조혈모세포이식학회지 Vol.5 No.2

배경:성인 ALL에서 동종 조혈모세포이식은 전처치요법 및 이식편대백혈병 효과에 의한 효과적인 백혈병세포의 제거가 가능하다는 측면에서 활발히 시행되고 있으나 자가 조혈모세포이식과 화학요법과의 비교 연구에서는 대상환자의 다양성 등으로 인하여 상이한 결과가 보고되었다. 그러나 최근 진단당시 환자의 임상적·세포생물학적 특성 및 관해유도요법 후의 백혈병세포의 제거 속도 등을 기준으로 한 위험인자가 정의되면서 이를 근간으로 위험도에 따른 관해 후 치료방침의 결정이 타당성 있는 접근방법으로 제시되고 있고, 특히 고위험군에서의 동종 조혈모세포이식의 역할이 강조되고 있다. 방법: 성인 ALL 고위험군에서 일차 완전관해시 동종 조혈모세포이식의 역할을 규명하기 위해 최근 5년간 가톨릭의대 조혈모세포이식센터에서 ALL로 진단 후 일차 완전관해 상태에서 동종 및 자가 조혈모세포이식을 시행받고 임상적 특성과 세포면역학적 특성 및 세포유전학적 검사결과가 모두 확인 가능하였던 환자 중 고위험군에 해당된 50례를 대상으로 후향적 분석을 시행하였다. 고위험군은 진단시 연령이 30세 이상인 경우, 백혈구수가 30,000/μL 이상인 경우, 관해유도기간이 30일 이상 소요된 경우, Ph 혹은 t(4;11)이 동반된 경우 중 하나 이상의 인자를 갖고 있는 경우로 정의하였다. 결과: 대상환자의 중앙연령은 30세(15~43세)이었고, 남녀 비는 27:23이었다. FAB 분류상 L1 29례(58.0%), L2 21례(42.0%)였으며, precursor B-lineage 항원이 양성인 경우는 36례(72.0%), T-세포 항원이 양성인 경우는 9례(18.0%), 골수구계 항원이 동시에 발현된 경우는 5례(10.0%)였다. 세포유전학적 검사상 23례(46.0%)에서 불량한 염색체유형 [Ph 19례, t(4;11) 4례]이 동반되었다. 전체 환자 중 31례에서 동종 조혈모세포이식을 시행하였으며, 19례에서는 자가 조혈모세포이식이 시행되었다. 동종 및 자가 조혈모세포이식 환자군간의 임상적 특성은 양군간의 유의한 차이가 없었다. 대상환자의 중앙 추적관찰기간은 27개월(7~72개월)이었고, 전체 환자의 2년 무병생존율 및 전체생존율은 각각 59.0±7.6%, 68.2±7.1%이었다. 조혈모세포이식에 따른 치료성적을 비교한 결과 전체생존율은 동종 조혈모세포이식군 71.4±8.6%, 자가 조혈모세포이식군 62.7±12.4%로 양군간의 유의한 차이가 없었던 반면, 재발율은 동종 조혈모세포이식군에서 유의하게 낮은 빈도를 보였으며(25.8% vs 52.6%, P=0.05), 무병생존율에 있어서도 각각 70.6±9.0%, 42.1±12.2%로 동종 조혈모세포이식군에서 보다 높은 경향을 보였다(P=0.07). 이식 후 생존율에 영향을 주는 위험인자를 분석한 결과, 진단시 연령, 백혈구수, 관해유도기간에 따른 차이는 관찰되지 않았다. 다만 Ph 혹은 t(4;11)이 동반된 경우에서 무병생존율이 동종(28.5±16.0% vs 94.4±5.4%, P=0.0002) 및 자가 조혈모세포이식군(18.1±11.6% vs 80.0±17.8%, P=0.0046) 모두에서 유의하게 감소되었다. 결론: 본 연구를 통하여 일차관해시 조혈모세포이식을 시행받은 고위험군 성인 ALL에서는 관해 후 치료법으로써 동종 조혈모세포이식이 우선적으로 고려될 수 있는 치료법임을 확인할 수 있었다. 이는 추후 국내에서도 보다 장기간의 추적관찰을 통한 전향적 임상연구를 시행하여 보다 정립된 관해 후 치료방침의 결정 필요성을 제시하였다는 측면에서 임상적 의의가 있을 것으로 사료된다. Background:Optimal postremission therapy remains controversial in adult patients with acute lymphoblastic leukemia (ALL). In this study, we compared allogeneic bone marrow transplantation (alloBMT) with autologous peripheral blood stem cell transplantation (autoPBSCT) using the result of the human leukocyte antigen typing (HLA). Methods:Patients were eligible if they were in first remission (CR1) and had either: adverse cytogenetics [Philadelphia chromosome (Ph), t(4;11)], age >30 years, required more than 1 induction course to achieve remission (time-to-CR1 >30 days) or presenting WBC >30,000/μL. From July 1994 to June 1999, 50 consecutive adult patients with high-risk ALL underwent HLA-matched alloBMT (n=31) or autoPBSCT (n=19) at the Catholic Hemopoietic Stem Cell Transplantation Center. Results:There were 27 males and 23 females with median age 30 (range, 15~43) years. The distribution of phenotype was as follows: L1 (n=29), L2 (n=21), precursor B (n=36), T (n=9), myeloid marker coexpression (n=5). Adverse cytogenetic abnormalities at diagnosis were shown in 23 (46.0%) cases. All pretransplant characteristics were well balanced between these two groups. Most patients were treated with total body irradiation containing regimen as part of the conditioning. With a median follow-up of 27 months in both groups, disease-free survival (DFS) and overall survival probabilities at 2 years were 59.0±7.6% and 68.2±7.1%, respectively. The relapse rates were significantly different between alloBMT and autoPBSCT groups (25.8% vs 52.6%, P=0.05). There was no significant difference in overall survival between the two groups. However, alloBMT had a trend toward better DFS (70.6±9.0% vs 42.1±12.2%, P=0.07). None of the pretransplant characteristics significantly affected outcome after transplantation, except adverse cytogenetics. Prognosis of ALL with Ph or t(4;11) was significantly poorer than that of the remaining high-risk ALL patients (P<0.01). Conclusion: We conclude that alloBMT appears to be more effective than autoPBSCT in prolonging initial CR for high-risk ALL patients. Prospective studies addressing additional clinical variables are needed to guide clinical decision making about transplant choices for adult patients with ALL. New therapeutic strategies for the management of ALL with adverse cytogenetics will be also required.