스트렙토조토신으로 유도된 신경세포사멸에서 비타민 C의 보호 기전 연구

이승희,한경훈,김현준,박광성,한성희,김정희,허재혁,Lee, Seung-Hee,Han, Kyung-Hoon,Kim, Hyun-Jun,Park, Kwang-Sung,Han, Sung-Hee,Kim, Jung-Hee,Heo, Jae-Hyeok 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.4

In this study, we analyzed the protective effects of the vitamin C in the streptozotocin (STZ)-induced apoptosis using the SH-SY5Y, a neuroblastoma cell line. The cells were pretreated with the vitamin C ($100{\mu}g$) for 30 min, followed by the 24-hr treatment with the 2.5-mM STZ. The cell-viability assay using the Cell Counting Kit (CCK)-8 revealed the cell-survival rate increased by 15% following the vitamin-C pretreatment compared to the STZ-only treatment. Moreover, we conducted the western-blot analysis to determine the protective effect of the vitamin C regarding the apoptosis. Compared to those in the STZ-only-treatment group, the p-ERK and Bcl-2 expressions increased in the vitamin-C-pretreatment group, whereas the p-JNK and Bax expressions decreased. The vitamin-C pretreatment increased the expression of the SOD-1, an antioxidant enzyme, by more than 30%, indicating its protective role in the STZ-induced oxidative stress. Also, we found both the intrinsic- and extrinsic-pathway mechanisms of the STZ-induced apoptosis. The results of this study $s{\mu}ggest$ vitamin C may help prevent the neurodegenerative diseases.

알코올로 인한 Wernicke disease의 치험 1례

이승희,라수연,김민석,정희,이유경,이태훈,김경훈,김성균,Lee, Seung-Hee,Ra, Su-Yeon,Kim, Min-Seok,Jung, Hee,Lee, Yu-Gyung,Lee, Tae-Hoon,Kim, Kyeong-Hun,Kim, Sung-Gyun 대한한방내과학회 2001 大韓韓方內科學會誌 Vol.22 No.4

Wernicke Disease is well known of nutriotional disorders Wernicke Disease is charaterized by ataxia, confusion and oculomotor disturbance. We diagnosis one patient, who has ataxia, confusion and oculomotor disturbance as Jusang(酒傷), and gave saenggangunbi-tang, bojungchiseub-tang and samchulgunbi-tang. We observed that clinical symptom and Liver function were improved by these herbal medicine Therefore We consider Wernicke Disease as Jusang(酒傷) and further reports with many case, however, will be needed.

급성 미로염으로 진단받은 환자의 한방 치험 1례

이승희,강주영,이수경,이창원,Lee, Seung-Hee,Kang, Ju-Young,Lee, Su-Kyung,Lee, Chang-Won 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.3

Objectives : The purpose of this study is to report the efficacy of using oriental medical treatment with acute labyrinthitis diagnosed patient.Methods : We experienced one case of acute labyrinthitis diagnosed patient treated with oriental medical treatment. To evaluate the results of this treatment, we measured the hearing recovery, decrease of tinnitus and vertigo. Decrease of tinnitus and vertigo was assessed by THI and Visual Analogue Scale(VAS).Results : VAS of tinnitus decreased from 1.5 to 0.2, and vertigo decreased from 2 to 0. THI decreased from 41 to 25.Conclusions : This study suggests that using oriental medical treatment is effective on Acute labyrinthitis.

`예륜(藝倫)`의 역사적 추이와 제도적 임계

이승희 ( Lee Seung Hee ) 민족문학사학회 2017 민족문학사연구 Vol.63 No.-

이 연구는 자율심의기구로 발족된 `예륜`이 국가권력과 문화주체의 역학관계의 변화에 따라 동태적으로 구성되어간 과정을 따라가면서, 그 제도적 임계를 통해 검열체제의 변동 징후를 살피고자 하였다. `예륜`의 창립은 `자율심의`를 통해 국가권력의 사회통제력으로부터 자율성의 영역을 확보하기 위한 문화세력의 기대와 그 궤를 같이 하지만, 사실 그 막후에는 `예총`을 내세워 그러한 기대를 제도화하도록 종용한 공보부가 있었다. 초기 3년여 동안 조직적 불비와 미숙함, 역능의 한계로 자율심의기구의 민낯을 드러냈지만, 이내 공보당국은 삼선개헌정국을 경과하면서 `예륜`의 사용법을 달리하기 시작했다. 대중문화의 비중이 점차로 증대되고 있는 와중에, 박정희체제를 위협하는 대내외 정세가 검열제도의 신속한 정비를 요구하고 있었기 때문이다. `예륜`의 조직개편과 권역확대는 바로 그러한 필요에 의해 취해진 것이었고, 이는 미디어의 대중적 파급력 여하를 관건으로 놓은 박정희정부의 문화통제에 대한 경제성 원리가 작용한 결과였다. 박정희의 종신집권을 위한 문화통제의 효율성 제고, 이것이 바로 `예륜`이 수행해야 할 몫이었다. 검열강화에 따른 피검열자에 대한 압력지수는 계속해서 높아져갔다. 이런 역사적 추이는 분명 `예륜`이 국가에 의해 장악되어간 과정이라 할 만한데, 역설적인 것은 국가권력의 강박적 검열이 강화될수록 여 기에 비/ 반동일화하는 새로운 피검열자가 구성되고 있었다는 점이다. 그 징후의 확실한 증거는 `예륜` 초창기부터 충실한 심의대상이었고 그저 고요하기만 했던 연극분야에서 심의 결과를 납득하지 못한 피검열자들의 반응이 공개되기 시작했다는 사실일 것이다. 이런 점에서 `예륜`의 10년은 뜻하지 않게 그러나 필연적으로 검열전선이 가시화되는 과정이기도 했다. 이를 정부가 감지했던 것일까. 비단 그렇지 않았을지라도, `예륜`은 거기서 끝나야 했다. 긴급조치 9호가 발동된 `비상시`의 검열권은 국가만이 가지고 있어야 하는 것이기 때문이다. 이렇게 보면 검열전선을 가시화한 것은 다름 아닌 박정희정부였던 셈이다. This study investigated the changes in the censorship system through the institutional criticality of the `Ye-ryun`, which was established as an self-censorship organization, following the process of dynamically changing according to the changes in the dynamics of state power and culture subject. The founding of `Ye-ryun` is coextensive with the expectation of the cultural power to secure the autonomy area to the social control power of the state power through `self-censorship`, but in fact, there was a Public Affairs Department at behind the scene, who operated `Ye-chong` to institutionalize such expectations. In the first three years, this self-censorship organization were exposed to organizational defects, inexperience, and limitations of their capabilities. However, the public authorities began to change the usage of `Ye-ryun` soon thereafter passing 1969. This period was noisy to the constitutional amendment issue for election for the third term. As the proportion of popular culture is gradually increasing, the internal and external situation that threatens the Park Chung Hee system demanded the quick maintenance of the censorship system. The organizational reorganization and enlargement of `Ye-ryun` were taken by such necessity, and this was the result of the economic principle of the cultural control of the Park government, which was the key to the media`s power to spread. It was the duty of `Ye-ryun` to enhance the efficiency of cultural control for to get tenurial seizure of power of Park Chung Hee. The pressure index on the censorship-object has continued to increase. This historical trend is obviously a process that has been dominated by the state, and the paradox is that as the obsessive censorship of the state power is strengthened, there has been constructed a new censorship-object who has non/anti-identification to censorship standard. The definitive proof of the indications was that in the field of the drama it had been a faithful censorship-object since the beginning of `Ye-ryun` and that was just calming, that the reactions of censorship-objects who did not understand the censorship results began to be revealed. In this sense, the decade of `Ye-ryun` was an unintended but inevitable process of visualizing the censorship front. Did the government detect this? Even if it was not so, the `Ye-ryun` had to end there. This is because only the state should have the right of censorship on emergency when the ninth Emergency Measure was triggered. In this way, it was nothing but the Park Chung Hee government that visualized the censorship front.

TV드라마 〈사랑의불시착〉의 서사 특징과 일본 4차 한류 현상의 상관관계 연구

이승희(Lee, Seung?hee) 건국대학교 GLOCAL(글로컬)캠퍼스 스토리앤이미지텔링연구소 2020 스토리&이미지텔링 Vol.20 No.-

악화일로를 달리고 있는 한일 관계 속에서도 최근 일본을 중심으로 한류의 기세가 거세다. 이른바 4차 한류로 명명(命名)되는 최근 한류 열풍의 도화선이 된 것은 넷플릭스를 통해 전 세계에 독점 공개된 TV드라마 〈사랑의 불시착〉과 〈이태원 클라쓰〉이다. 본고는 이 가운데 드라마 〈사랑의 불시착〉을 중심으로 드라마의 서사적 특징과 한류 열풍과의 상관관계를 일본의 사회, 문화적 배경을 통해 고찰하였다. 연구 결과 다음음과 같은 점들을 확인하였다. 첫째 북한을 소재로 한 설정은 일본인들의 독특한 북일관계와 북한 인식 등을 배경으로 남성 시청층을 새로운 드라마 소비층으로 확보하였다. 둘째 〈사랑의 불시착〉에 등장하는 여성 캐릭터들의 주체적이고 당당한 모습은 여전히 뿌리 깊은 가부장제와 여성에 대한 경직된 문화가 잔존해있는 일본 사회의 여성들에게 자신의 목소리를 찾아주고 대리만족을 느끼게 해줌으로써 드라마에 더욱 열광하도록 만들었다. 셋째, 드라마 속에 일관되게 흐르는 웃음 코드 속에서 일본인들에게 익숙한 전통 예능인 만자이(漫才) 요소를 발견할 수 있었으며, 끝으로 드라마 〈사랑의 불시착〉 속의 주요 공간적 배경인 북한과 북한 주민들의 리얼한 일상의 풍경은 일본에서도 붐을 이루고 있는 ‘쇼와 노스탤지어(昭和ノスタルジア)’ 현상과 결합하며 드라마에 대한 흡입력을 높이는 데 기여했다. Despite the worsening relationship between Korea and Japan, the Korean Wave has been on the rise recently, especially in Japan. The so-called fourth wave of Hallyu, or the Korean Wave, has sparked the latest wave of Korean Wave, which was exclusively released on Netflix, Crash Landing on You and Itaewon Class. Among them, the study considered the relationship between the box office factors of the drama and the Korean Wave craze through the social and cultural backgrounds of Japan. The study identified the following points: First, the North Korea-based setting has secured a male audience as a new drama consumer based on the unique Japanese-North Korea relationship and awareness of North Korea. Second, the self-reliant and imposing appearance of female characters in Crash Landing on You has made Japanese women, who still maintain a deep-rooted patriarchal system and a rigid culture of women, more enthusiastic about the drama by finding their voices and making them feel vicarious satisfaction. Third, we could find Manzyai element, a traditional entertainment that is familiar to Japanese people in the drama, and finally, the real daily scenery and story created by North Koreans and North Koreans, the space in the drama Crash Landing on You, combined with the Shōwa Nostalgia phenomenon, which is also booming in Japan, contributing to the increased suction power to the drama.

수준진단을 통한 지방행정혁신 고도화 방안 - C 도 혁신진단 조사를 바탕으로-

이승희,노규성,Lee, Seung-Hee,Noh, Kyoo-Sung 한국디지털정책학회 2005 디지털융복합연구 Vol.3 No.2

Local decentralization and administration innovation is the most important problem the government confronted with at the present time. So local government must be follow them. Therefore, local government need to prepare whole process on this. From now on, local government must be develop own innovation model and strategy then, forward with innovation plan classified by step. This study reviewed the significance and necessary of local administration innovation and examined the necessary of level diagnosis of local administration innovation. And We diagnosed administration innovation of C province, then analyzed the result and proposed Altitude plans of administration innovation.

포털사이트의 지각된 서비스 품질이 후속 행동에 미치는 영향에 관한 연구

이승희,김혜경,Lee, Seung-Hee,Kim, Hye-Kyoung 한국디지털정책학회 2008 디지털융복합연구 Vol.6 No.1

This paper is aimed to exam factors in the perceived service quality of web portal site and to analyze their effects on customer satisfaction. And this paper analysis satisfaction effects on revisit intention. To accomplish this purpose, this study examined previous studies and summarized core factors of service quality. Form literature survey, we drawn core factors. They are convenience, technologies, valuable of contents and service, communication, positioning. These core factors will affect on customer trust, satisfaction and satisfaction will affect on revisit intention. This study examined previous studies and summarized core factor in perceived service quality of web portal site. Fourteenth hypothesis were developed. Data for empirical testing were collected through survey to portal sites user. The results of this study are as follows; First, we find that service, communication and positioning have positive influence on the trust. Second, convenience, valuable of contents and postioning factors have a positive influence on the satisfaction. Third, it is shown that satisfaction have a positive influence on the revisit intention.

섬유주세포에서 Erythropoietin이 일산화질소의 생성에 미치는 영향

이승희,김재우,Seung Hee Lee,Jae Woo Kim 대한안과학회 2011 대한안과학회지 Vol.52 No.12

Purpose: To investigate the effects of erythropoietin (EPO) on the production of nitric oxide in cultured human trabecular meshwork cells (HTMC). Methods: Primarily cultured HTMC were exposed to 0, 0.5, and 1.0 U/ml EPO using serum-deprived media for 2 days. Production of nitric oxide and cellular survival were assessed with Griess assay and MTT assay, respectively. Expression of EPO mRNA receptor and activity of eNOS were assessed with RT-PCR. Results: EPO did not affect the survival of HTMC (p > 0.05). EPO increased the production of nitric oxide (p < 0.05) accompanied with increased eNOS activity. Conclusions: EPO had no effect on the cellular survival under serum-deprived conditions. EPO increases the production of nitric oxide by increasing eNOS activity. J Korean Ophthalmol Soc 2011;52(12):1514-1518

공용공간과 복리시설의 변화를 중심으로 한 프랑스 근대 도시주거의 변천에 관한 연구

이승희,유우상,Lee Seung-Hee,Yoo Uoo-Sang 한국주거학회 2005 한국주거학회 논문집 Vol.16 No.5

Since Mapo Apartment was introduced as a new urban housing type in the early sixties, apartment has been a typical urban housing in our country. In these days, according to various life-styles and new attitudes about the quality of life, apartment has been developed in various types like high rise residential complex and apartments with special themes. This study has been focused on the transition of modem urban housing in France. The origin of a word, apartment, has been defined and history of apartment in French urban life has been analyzed focusing on the common space and community facilities. Representative apartments in the 18th, 19th and 20th century were selected and comparatively analyzed. Especially in the 19th century, urban housing for working class had been a major concern among the communist and the bourgeoisie and has its own characteristics relative to each other. The characteristics shown in the apartment by the communist in France have been followed in the Korean apartments since 1960's, then the recent trends are rapidly changing in the housing market in Korea. Thus, the findings of this study can be very useful to understand the recent changes of diverse housing types in our society and also be very helpful to prospect our urban housing types in the future according to the changes of new lift styles.

모바일 앱 활용 치아형태학 수업에서의 학습 만족도 제고 요인

이승희,정효경,Lee, Seung-Hee,Jung, Hyo-Kyung 한국산업융합학회 2022 한국산업융합학회 논문집 Vol.25 No.5

This study was conducted on 54 freshmen of the department of dental technology in D University to examine the effect of dental morphological practice mobile application utilization on the students' perception of class and satisfaction with learning. Major results of the study showed that satisfaction and utility towards functions of mobile application strengthened positive perception of dental morphology class, leading to improvement of satisfaction with learning, which suggested that functional convenience and utility in the use of applications were the effective factors for increasing the satisfaction with learning. Those results need to be given important consideration in designing the class using the mobile applications.