ECM-associated molecules in hemodialysis patients

백지현,백지현 대한내과학회 2023 대한내과학회 추계학술대회 Vol.2023 No.2

Response to Nonallergenic Irritants in Children With Allergic and Nonallergic Rhinitis

백지현,조은혜,김미애,이승원,강유선,신윤호,지혜미,정영호,한만용 대한천식알레르기학회 2016 Allergy, Asthma & Immunology Research Vol.8 No.4

Purpose: Nonallergenic irritants can aggravate the symptoms of rhinitis. We investigated the clinical responses of children with allergic rhinitis (AR) and nonallergic rhinitis (NAR) to nonallergenic irritants, and identified factors associated with these responses. Methods: Children with chronic rhinitis (n=208) were classified as having AR or NAR based on the presence of aeroallergen-specific IgE. Healthy controls (n=24) were recruited for comparison. The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines were used to classify patients, and their irritant score (0-21 points) and current symptom score (5-35 points) were measured. Subjects with irritant scores ≥3 and <3 were classified as having irritant and nonirritant rhinitis, respectively. Results: The mean age of enrolled subjects was 6.8 years (range: 1.8-16.0 years). The AR and NAR groups had similar irritant scores (P=0.394) and proportions of subjects with irritant scores ≥3 (P=0.105). Irritant score correlated positively with symptom score (P=0.005), and the proportion of subjects with irritant scores ≥3 was greater in children with moderate-severe rhinitis than in those with mild rhinitis (P=0.046). Multiple logistic regression analysis indicated that the presence of atopic eczema increased the risk for sensitivity to a nonallergenic irritant (aOR=2.928, 95% CI 1.567-5.473, P=0.001). Conclusions: Response to a nonallergenic irritant was useful for gauging the severity of rhinitis, but not for differentiating AR from NAR. AR and NAR patients with atopic eczema may increase nasal sensitivity to nonallergenic irritants.

Clinical Factors Associated with Hepatitis A Virus Seropositivity in HIV-Infected Adults Living in a Country with an Epidemiologic Shift for Hepatitis A Virus Infection

백지현,김창오,박준용,정수진,구남수,김혜원,한상훈,최준용,송영구,김준명 대한의학회 2012 Journal of Korean medical science Vol.27 No.8

The number of HIV-infected individuals susceptible to Hepatitis A virus (HAV) infection is increasing in Korea; however, it has proven difficult to devise a vaccination policy therefore because limited seroepidemiologic data exists for them. Accordingly, anti-HAV IgG was measured in 188 HIV-infected adults between July 2008 and July 2010. The nadir CD4+ T lymphocyte counts were not different between the HAV-positive and .negative groups (197 ± 138 vs 202 ± 129, P = 0.821). The only factor independently associated with seropositive status was age under 40 yr old (OR 0.017, P < 0.001). Our findings suggest that HAV vaccination in HIV-infected adults should be targeted at persons under the age of 40 yr.

돈의문ㆍ천호 뉴타운 사업 속도 붙는다

백지현,하유정,Baek, Ji-Hyeon,Ha, Yu-Jeong 한국주택협회 2006 주택과 사람들 Vol.197 No.-

재건축에 대한 각종 규제로 뉴타운과 재개발에 대한 관심이 높아지고 있다. 서울시는 사업 속도를 높이기 위해 행정 절차를 간소화하고 용도 지역 변경과 용적률 제한도 완화했다. 입지 조건이 좋은 천호뉴타운과 시내 중심부에 위치한 돈의문뉴타운을 찾아가봤다.

Review of Suicide Prevention Programs: Massachusetts, United States, in Comparison with Seoul

백지현,박종익,안정훈,노성원,허정윤,Maurizio Fava,David Mischoulon,전홍진 대한신경정신의학회 2015 PSYCHIATRY INVESTIGATION Vol.12 No.3

Suicide is a tragedy that has massive impact on society. In order to prevent suicide, active government intervention is necessary. The suicide rate in Seoul is rapidly increasing and is more than five times higher than that in the state of Massachusetts (MA) during the last decade, especially in the elderly. The suicide prevention program of MA is one of the most effective suicide prevention programs in the United States. The program views suicide as a preventable public health problem, and emphasizes treatment of depression and de-stigmatization of mental health illnesses to prevent suicide. Also, through active collaboration with mental health professionals, they try to identify atrisk populations and help them to get medical interventions. The program also actively collaborates with the regional coalition program and the Samaritans in taking care of the elderly, and supports the elderly in feeling worthwhile after retirement by helping them to work for communities as volunteers. For its part, the Seoul suicide prevention program puts more emphasis on “life respect culture” and “emotional support to high risk individuals by regular visiting”. The annual budget of the Seoul suicide prevention program is one-quarter and that for mental health is about one-twentieth that of MA. Considering the high suicide rate and lower mental health service usage in Seoul, it is crucial to raise awareness of depression and decrease the stigma on mental illnesses. Furthermore, educational efforts with long-term investment in research on suicide are necessary.

Smart Stress Care: Usability, Feasibility and Preliminary Efficacy of Fully Automated Stress Management Application for Employees

백지현,Jeong Hyun Kim,Sohee Oh,Ju Young Kim,Soyoung Baik 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.11

Objective We developed a fully automated smartphone-based stress management application and explored its usability, potential feasibility, and preliminary efficacy for stress management in Korean employees. Methods Healthy employees working in large public enterprises were enrolled. Participants used our automated stress management application for four weeks. With the application, they monitored their stress level and life style factors. Personalized stress management techniques, including psychoeducation and cognitive behavioral technique, were also provided based on their stress level and lifestyle pattern. In 2014, additional relaxation techniques were incorporated. Participants’ mental health status and lifestyle pattern were self-assessed at baseline and at 4 weeks after using the application. Results A total of 68 subjects were recruited. The application generally received high satisfaction rating. After the intervention, perceived stress level was significantly decreased, both in 2013 and 2014 (BEPSI-K score pre. vs. post. 14.27 vs. 11.00, F=12.49, p=0.001 in 2013; 12.05 vs. 10.00, F=17.18, p<0.001). In 2014, depression symptom severity was also significantly decreased (CES-D score pre- vs. Post-, 17.66 vs. 11.95, F=9.76, p=0.004). The effects were more significant in females and in those <35 years. Conclusion Our fully automated stress management application is acceptable and usable, showing preliminary efficacy for reducing employees’ stress levels.

히스토그램의 변곡점을 이용한 영상 신호의 잡음 제거

백지현,김남호,Baek, Ji-Hyeon,Kim, Nam-Ho 한국정보통신학회 2020 한국해양정보통신학회논문지 Vol.24 No.11

현대사회에서 CCTV, 블랙박스 등 다양한 영상기기로 편리함을 도모한다. 하지만 야간에서 촬영된 영상이나 영상 신호가 송, 수신되는 과정에서 잡음이 빈번하게 발생한다. 이러한 잡음을 제거하지 않으면 영상의 식별이 어렵다는 문제점이 발생한다. 따라서 영상 정보에서 영상의 잡음 제거는 필수불가결한 단계이다. 영상 잡음 중 대표적인 임펄스 잡음으로 Salt and Pepper 잡음이 있다. 잡음을 제거하기 위한 방법으로 선행연구가 진행되어져 왔고 그중 대표적인 방법으로 CWMF, MMF, A-TMF 등이 있다. 이러한 필터들은 공통적으로 저밀도 잡음 영역에서는 우수한 성능을 보이지만 고밀도 잡음 영역에서 잡음 제거 성능이 다소 부족하다는 단점이 있다. 따라서 제안한 알고리즘은 히스토그램 그래프의 변곡점을 이용하여 영역을 나누어 특이점을 제거하고, 히스토그램 분포를 이용한 가중치 필터를 제안한다. 객관적인 판단을 위해 PSNR을 이용하였다. In modern society, various video devices such as CCTV and black boxes are used for convenience. However, noise is frequently generated in the process of transmitting and receiving video images and video signals photographed at night. If such noise is not eliminated, the problem that the image is difficult to identify is generated. Accordingly, noise elimination of images in the image information is an indispensable step. Salt and Pepper noises are typical impulse noises among image noises. Previous research has been carried out as a method for eliminating noise, and CWMF, MMF and A-TMF are typical methods. In common, such a filter exhibits excellent performance in a low-density noise area, but a disadvantage is that noise elimination performance in a high-density noise area is somewhat insufficient. Accordingly, the proposed algorithm uses the inflection point of the histogram graph to separate areas and remove singular points, and proposes a weighting filter utilizing histogram distribution. PSNR was used for objective judgment.

Salt and Pepper 잡음 환경에서 히스토그램의 분포를 이용한 스위칭 필터

백지현,박준모,김남호,Baek, Ji-Hyeon,Park, Jun-Mo,Kim, Nam-Ho 한국융합신호처리학회 2020 융합신호처리학회 논문지 (JISPS) Vol.21 No.3

With the recent development of communication equipment, the demand for communication equipment is gradually increasing. Accordingly, various signal processing has been studied. In the case of an image, noise removal is an indispensable step because noise propagation problems may occur if noise is not removed in the pre-processing process. Salt and Pepper noise is a typical impulse noise with two extremes. Various studies have been conducted to remove such noise, and there are CWMF, MF and MMF. However, the existing methods are somewhat insufficient in the high-density noise region. Therefore, in this study, we have proposed an algorithm that filters the size of the mask according to the number of noises inside the 7×7 mask and filters it with a modified switching filter using the histogram distribution of the image. In the case of the proposed algorithm, noise can be effectively removed in a high-density noise region. For objective judgment, PSNR was used to compare and analyze with existing algorithms. 최근 통신장비가 발달함에 따라 통신장비의 수요가 점차 늘어나고 있는 추세이다. 이에 따라 다양한 신호 처리가 연구되어져 왔다. 그 중 영상은 전처리 과정에서 잡음을 제거하지 않으면 오류의 전파라는 문제를 야기할 수 있기 때문에 잡음 제거가 필수불가결한 단계이다. Salt and Pepper 잡음의 경우 두 개의 극값을 가지는 대표적인 임펄스 잡음이다. 이러한 잡음을 제거하기 위해 다양한 연구가 진행되어 왔으며 CWMF, MF, MMF 등이 있다. 하지만 기존의 방법들은 고밀도 잡음 영역에서 다소 미흡한 모습을 보인다. 따라서 본 연구에서는 7×7 마스크 내부의 잡음개수에 따라 마스크의 크기를 다르게 하고, 영상의 히스토그램 분포를 이용하여 변형된 스위칭 필터로 필터링하는 알고리즘을 제안하였다. 제안한 알고리즘의 경우 고밀도 잡음 영역에서 효과적으로 잡음을 제거할 수 있으며, 객관적인 판단을 위해 PSNR을 이용하여 기존의 알고리즘들과 비교, 분석하였다.

Comparisons of Subthreshold Versus Full Posttraumatic Stress Disorder Distinguished by Subjective Functional Impairment Among Train Drivers: A Population-Based Nationwide Study in South Korea

백지현,김지혜,김빛나,박승진,Maurizio Fava,David Mischoulon,이동수,전홍진 대한신경정신의학회 2017 PSYCHIATRY INVESTIGATION Vol.14 No.1

Objective: Subthreshold posttraumatic stress disorder (SPTSD), a condition that meets the full symptomatic criteria of posttraumatic stress disorder (PTSD) without subjective functional impairment, has yet to be fully investigated. In this study, we aimed to determine the prevalence and characteristics of SPTSD. Methods: The web-based survey including psychiatric diagnosis and experience of human error was conducted in actively working train drivers in South Korea. Results: Of the 4,634 subjects, 103 (2.23%) were categorized as full PTSD and 322 (6.96%) were categorized as having SPTSD. Individuals with full PTSD showed higher impulsivity and anxiety compared to those with SPTSD and those without PTSD, while those with SPTSD had more frequent clinically meaningful depression, posttraumatic stress, and alcohol and nicotine dependence and significant human error. Conclusion: Despite not qualifying as a subjective functional disability, SPTSD still had significant psychiatric symptoms. More clinical attentions need to be given to the diagnosis and treatment of SPTSD.

Effect of hydrochloric acid concentration on microwave-assisted acid hydrolysis of proteins

백지현,김인영,신동원,김수환,김여선,이다빈,김정권 한국분석과학회 2016 학술대회논문집 Vol.2016 No.11