섬망 환자의 지각된 낙인 척도 개발 및 타당성 검증

김선영,김성완,김재민,신일선,윤진상,Kim, Seon-Young,Kim, Sung-Wan,Kim, Jae-Min,Shin, Il-Seon,Yoon, Jin-Sang 한국정신신체의학회 2015 정신신체의학 Vol.23 No.2

연구목적 본 연구는 '섬망환자의 지각된 낙인 척도(Perceived Stigma of Delirium Scale, PSDS)'를 개발하고 신뢰도와 타당도를 평가하여 섬망을 경험한 환자의 지각된 낙인을 측정하고자 시행되었다. 방 법 기존 문헌과 낙인 관련 척도를 고찰 및 참고하여 7문항의 PSDS 예비 척도를 구성하고, 섬망에서 회복된 128명의 환자를 대상으로 PSDS와 디스트레스 온도계(Distress Thermometer, DT)를 측정하였다. 탐색적 요인 분석을 시행하여 낙인 척도의 요인 구조를 확인하였다. 신뢰도 검증을 위해 내적 일치도와 검사-재검사 신뢰도를 분석하였다. 공시타당도는 PSDS 총점과 DT의 상관 분석을 통해 확인하였다. 결 과 예비 척도의 요인 분석을 시행한 결과 단일 요인이 추출되었다. 예비 척도 7문항 중 1개 문항은 낮은 요인 부하량을 가져 제외하였다. PSDS의 내적 일치도의 분석을 위해 시행한 Cronbach's ${\alpha}$ 값은 0.85였다. PSDS 총점의 검사-재검사간 상관 계수는 0.71이었으며, 각 문항별 상관 계수는 0.58에서 0.83사이었다. PSDS의 총점과 DT는 유의한 상관관계를 보였다. 결 론 본 연구는 PSDS가 섬망에서 회복된 환자의 지각된 낙인을 측정하는데 있어서 신뢰할만한 도구임을 확인하 였다. 본 척도 연구를 기반으로, 후속 연구와 다기관 연구를 통해 임상적 유용성의 평가가 이루어져야 할 것이다. Objectives : This study developed and validated the Perceived Stigma of Delirium Scale(PSDS), which is designed to measure perceived stigma associated with delirium in patients suffering from that disorder. Methods : Based on a literature review of scales assessing stigma, a preliminary scale comprising seven items was developed. After recovering from delirium, 128 patients completed the PSDS and the Distress Thermometer (DT). Factor analysis was used to examine construct validity, and internal consistency and test-retest reliability were examined to ensure reliability. Concurrent validity was assessed using the correlation between the total scores on the PSDS and the DT. Results : Factor analysis yielded a single-factor structure from the seven candidate items. One item was excluded due to low factor loading. The internal consistency was computed and Cronbach's ${\alpha}$ was 0.85 for the total score. The overall test-retest reliability was 0.71, with items ranging from 0.58 to 0.83. The total score on the PSDS was significantly correlated with the DT score. Conclusions : The PSDS may be a reliable, valid instrument for evaluating perceived stigma in patients who have recovered from delirium. Further study of the perceived stigma by delirium patients is required to assess the implications of the PSDS for clinical practice and research.

Meta- and Gene Set Analysis of Stomach Cancer Gene Expression Data

김선영,Jeong-Hwan Kim,Heun-Sik Lee,Seung-Moo Noh,Kyu-Sang Song,June-Sik Cho,Hyun-Yong Jeong,Woo Ho Kim,Young-Il Yeom,김남순,Sangsoo Kim,Hyang-Sook Yoo,Yong Sung Kim 한국분자세포생물학회 2007 Molecules and cells Vol.24 No.2

고속 수렴성을 갖는 딥 러닝 기반 채널 부호 복호기

한석주(Han Seokju),하정석(Ha Jeongseok) 한국통신학회 2020 한국통신학회 학술대회논문집 Vol.2020 No.8

통계분석을 이용한 지역별 산불위험시기 구분

김선영,이시영,안상현,신영철,오정수,Kim, Sun-Young,Lee, Si-Young,An, Sang-Hyun,Shin, Young-Chul,Oh, Jeong-Soo 한국방재학회 2002 한국방재학회논문집 Vol.2 No.1

전국단위로 시행되고 있는 산불위험시기가 전국 9개 지역(강원, 경기, 경남, 경북, 전남, 전북, 제주, 충남, 충북)과 차이가 있는지를 알아보기 위하여 산불발생건수와 피해면적을 가지고 순기별로 구분하여 상관분석을 실시하였다. 분석 결과 산불발생건수에서는 모든 지역에서 유의성이 있는 것으로 나타났고, 산불피해면적에서는 경남, 제주와 유의성이 없는 것으로 나타났다. 이에 전국을 대상으로 모든 지역을 설명하기에는 부족하므로 전국 9개도를 대상으로 하여 산불위험시기를 구분하기 위하여 산불발생과 피해면적을 이용하여 분산분석의 다중검정을 실시하고 순기별로 유의성 검정을 실시하였다. 그 결과 산불발생에 있어서 제주를 제외한 지역에서 1% 유의성이 있었고, 산불피해면적은 강원, 제주를 제외한 지역에서 1% 유의성을 보였다. 각 지역별로 위험시기를 구분할 수 있지만 행정적 효율성을 높이기 위하여 지역별 상관분석 결과를 이용하여 산불위험시기가 비슷한 중부권(강원, 경기, 경북, 전북, 충남, 충북), 남부권(경남, 전남), 그리고 제주권(제주)으로 분류하였다. 산불발생시기에 있어서는 중부권은 2월중순${\sim}$5월상순까지 전체의 81%가 발생한 반면 남부권은 1월하순${\sim}$4월중순까지 전체의 71%가 발생하였다. 산불피해면적에 있어서는 중부권은 2월중순${\sim}$5월상순까지 전체의 98% 가 발생한 반면 남부권은 1월하순${\sim}$4월중순까지 전체의 82%가 발생하였다. Forest fire danger period in nine Provinces (Gangwondo, Kyonggido, Gyeongsangnamdo, Gyeongsangbukdo, Jeollanamdo, Jeollabukdo, Jejudo, Chungcheongnamdo, Chungcheongbukdo) has turned out to be similar to recognize whether there are some differences between each Provinces, we used correlation analysis with number of occurrence and damage area by an interval of ten-day period. Based on this analysis, there was significant numbers of occurrence at all areas wish serious burns except Gyeongsangnamdo and Jejudo Provinces. Since persuasive power is insufficient as danger period of forest fire applies equally to nine Provinces, statistical analysis using number of forest fire occurrence and burned area are executed. And then, a analysis of variance(ANOVA) test of significance by an interval of ten day period is carried out. As a result of this analysis, there showed significant at 1% level for number of occurrence except Jejudo, and is also showed significant at 1% level for burned area except Gangwondo and Chejudo. Through regional correlation analysis for danger period, we classified three parts of Middle region (Gangwondo, Kyonggido, Gyeongsangnamdo, Gyeongsangbukdo, Jeollabukdo, Chungcheongnamdo, Chungcheongbukdo) Southern region (Gyongsangnamdo, Jeollanamdo) and Jejudo region. With respect to forest fire occurrence time, Middle region showed from the middle of February to first of May that amounts to 81% of entire occurrence in this region, and Southern region begins with at the last of January to the middle of April covering 71%. In terms of forest fire burned areas, it appears at the middle of February to the first of May, occupying 98% in Middle region, and Southern region showed burned areas from the last of January to the middle of April amounting to 82% of total occurrences.

원락(原絡) 배혈(配穴) 전침 자극이 백서의 족과 염좌(捻挫) 통증에 미치는 영향(影響)

김선영,구성태,김경식,손인철,Kim, Sun-Young,Koo, Sung-Tae,Kim, Kyoung-Sik,Sohn, In-Cheul 경락경혈학회 2005 Korean Journal of Acupuncture Vol.22 No.1

Objectives : In the present study, the effect of electroacupuncture (EA) applied to SI6 and won-rak point on the ankle sprain model was examined. A common source of persistent pain in humans is the lateral ankle sprain. Methods : To model this condition, the rat's right ankle was bent repeatedly, overextending lateral ligaments, for 4 min under enflurane anesthesia. The rat subsequently showed swelling of the ankle and a reduced stepping force of the affected limb for the next several days. The reduced stepping force of the limb was presumably due to a painful ankle. EA was applied to the several acupuncture point on the contralateral forelimb for 30 min under gaseous anesthesia. After the termination of EA, behavioral tests measuring stepping force and Paw volume were Periodically conducted during the next 4 h and 18 h respectively. Results : EA applied to $SI_6$ with won-rak point produced more powerful improvement of stepping force of the sprained foot than to $SI_6$ alone lasting for at least 4 h. However, neigher $KI_4$ point nor $BL_{64}$ point produced any significant increase of weight bearing force. The improvement of stepping pressure was interpreted as an analgesic effect. The analgesic effect was specific to the acupuncture point since the analgesic effort on the ankle sprain pain model could not be mimicked by EA applied to $KI_4$ or $BL_{64}$. In addition, EA applied to $SI_6$ with won-rak combination point showed inhibitory effect on the paw edema induced by ankle sprain. Also, COX-2 protein expression increased by ankle sprain were suppressed by the EA stimulation. Conclusion : These data suggest that EA with won-rak combination point produces a more potent analgesic effect on the ankle sprain pain model in the rat and that EA with won-rak combination point induced anti-inflammatory effect through the suppression of COX-2 protein expression.

신경초종의 세침흡인 세포학적 소견

김선영,남혜주,김정희,조영록,강유나,이상숙,Kim, Sun-Young,Nam, Hae-Joo,Kim, Jung-Hee,Cho, Young-Rok,Kang, Yu-Na,Lee, Sang-Sook 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.1

Schwannoma is a benign encapsulated nerve sheath tumor and is histologically characterized by a mixture of Antoni type A and B tissue. A preoperative diagnosis of schwannoma by fine needle aspiration cytology or by any other means is important a preserve clinically important nerves. Therefore, it is necessary to make a specific cytological diagnosis of nerve sheath tumor. However, there are a few reports regarding cytological features of schwannoma in Korea. We experienced seven cases of solitary schwannoma and here we report their characteristic cytological features with a review of literatures. The characteristic features of schwannoma on cytology were the presence of both Antonl type A and B tissue. The cytologic findings common to all cases of schwannoma generally corresponded to the histologic findings of Antoni type A tissue, consisting of fragments of tightly cohesive fascicles with variable cellularity. Dense fibrillary substances were found, along with palisading nuclei and Verocay bodies. Individual tumor cells consisted of cohesive cells haying spindle or oval nuclei, with pointed ends and Indistinct cell borders. Variation in nuclear size and shape was also present. The Antoni type B consisted of scattered wavy or short spindle cells and some histiocytes and lymphocytes in the abundant myxoid background with formation of microcysts. Immunohistochemistry for S-100 protein revealed a uniformly strong positive reaction and was helpful to make more accurate diagnosis of schwannoma.

말기 신장질환자의 우울증

김선영,김재민,윤진상,Kim, Seon-Young,Kim, Jae-Min,Yoon, Jin-Sang 대한생물정신의학회 2008 생물정신의학 Vol.15 No.4

Depression is common in patients with end-stage renal disease(ESRD) and has a negative effect on the quality of life, functional ability, and mortality of the patients, with a prevalence rate as high as 20-25%. Especially, the increasing tendency of mortality in ESRD patients is associated with recent or current depression, and the suicide rate is also increased by depression in patients with ESRD. Therefore, accurate detection and appropriate treatment of depression is very important in ESRD patients. Also, a deferential diagnosis is needed concerning uremic symptoms and depression in ESRD patients. However, there has been little data so far particularly in terms of randomized clinical trials. This review focused on the recent knowledge of depression in ESRD, and could encourage clinical study and trials in this field.

고립성 골 전이를 동반한 식도편평세포암에서 동시 항암화학방사선 요법 후 완전관해를 보인 1례

김선영,서민호,최혁순,김은선,금보라,진윤태,이홍식,엄순호,김창덕,류호상,이우진,전훈재,김예지,Sun Young Kim,Min Ho Seo,Hyuk Soon Choi,Eun Sun Kim,Bora Keum,Yoon Tae Jeen,Hong Sik Lee,Soon Ho Um,Chang Duck Kim,Ho Sang Ryu,Woo Jin Lee,Hoon Jai 대한소화기암연구학회 2013 Journal of digestive cancer reports Vol.1 No.1

There is no established treatment for esophageal carcinoma with metastasis. For the metastatic esophageal squamous cell carcinoma, chemotherapy or best supportive care according to patient's performance status are accepted as an available treatment. We report a case of complete remission after concurrent chemoradiotherapy for esophageal squamous cell carcinoma with metastatic lesion in 5th thoracic vertebrae. A 57-year-old man with ongoing dysphagia and weight loss was admitted to our hospital. On the endoscopic and radiologic imaging evaluation,the patient was diagnosed as a squamous cell carcinoma of esophagus with solitary metastatic lesion in 5th thoracic vertebrae. The patient was treated with combination chemotherapy (5-fluorouracil (5-FU) and cisplatin) and concurrent radiotherapy for two months to relieve dysphagia. Because metastatic lesion in thoracic vertebrae was located near the primary esophageal tumor, the metastatic lesion could be included within the radiation field. After concurrent chemoradiotherapy, consecutive 4 cycles of chemotherapy had been carried out. Primary esophageal tumor with metastatic lymph nodes and metastatic lesion in 5th thoracic vertebrae disappeared on follow up computed tomography (CT) and positron emission tomography-CT (PET-CT). Follow up endoscopic biopsy revealed no remnant malignant cells at previous primary cancer lesion.

의료인과 간호학생의 웰다잉 의미에 관한 주관성 연구

김선영,허성순,김분한,Kim, Seon Young,Hur, Sung Soun,Kim, Boon Han 한국호스피스완화의료학회 2014 한국호스피스.완화의료학회지 Vol.17 No.1

목적: 본 연구는 의료인과 간호학생의 웰다잉 의미와 주관성 유형을 확인하고, 유형별 특성을 분석하기 위해 Q 방법론을 적용한 조사연구이다. 방법: 간호학과 학생 8명, 호스피스전문병원 임상간호사 3명을 대상으로 심층면담과 선행연구고찰을 통해 102개의 Q-모집단을 구성하였으며, 이후 Q-방법론의 전문가인 간호학과 교수 1명과 간호학과 박사과정 중인 2명의 의견 교환 및 재조정을 통하여 총 33개의 Q-표본을 선정하였다. 4년제 간호학과 학생 11명과 경기도 일개 3차 종합병원의 간호사 9명과 의사 2명을 대상으로 총 22명의 P-표본을 대상으로 하였다. P-표본은 선정된 33개의 진술문을 강제 정상분포가 되도록 7점 척도 상에 분류하도록 하였고, 양극단에 분류한 진술문과 관련하여 추가 진술문을 작성하도록 하였다. 수집된 자료는 PC-QUANL Program으로 요인 분석하였다. 결과: 분류된 의료인의 웰다잉 의미 유형은 모두 3가지로 나타났으며 이들 유형에 의해 설명된 전체 변량은 57.97%였다. 제1형은 '현실중시형'으로 부담 없이 아름다운 모습으로 임종하는 것에 의미를 두었다. 제2형은 '관계중시형'으로 죽기 전 자선을 베풀고 주변인들과 화해와 용서의 시간을 갖는 것에 의미를 두고 있었다. 제3형은 '자연순응형'으로 살만큼 살다 가족의 간호를 받으며 임종하는 것에 의미를 두었다. 결론: 웰다잉에 관한 의료인과 간호학생의 주관성은 임종을 맞이하는 환자간호에 영향을 미친다. 따라서 의료인과 간호학생은 삶과 죽음에 대한 깊은 통찰을 가져야 하며, 이를 위해 웰다잉에 대한 주관성 유형별 특징에 맞는 죽음교육이 필요하다. Purpose: This study was conducted to examine understanding of the meaning of well-dying and types of such views held by medical practitioners and nursing students. Methods: The Q-methodology was used to analyze the subjectivity of each item. The P-sample was made up of 22 medical practitioners or nursing students. The P-sample was instructed to rate 33 statements using a 7-point scale to obtain forced normal distribution. They were asked to make extra comments on the statements that were placed on both ends of the distribution curve. The PC-QUANL Program was used for the factor analysis of the collected data. Results: The participants had three types of meaning of well-dying. Total variance explained by these types was 57.97%" where type 1 was "reality-oriented", type 2 "relationship-oriented" and type 3 "obeying-the-nature". Conclusion: The participants' subjective views on well-dying influences their medical practice on patients who are facing death. Therefore, medical practitioners should have profound insights concerning life and death. To that end, a training program is needed to help medical practitioners develop a proper view on well-dying by subjectivity type.

폐결핵에 병발하는 기관지 결핵에 관한 연구

김선영 ( Sun Young Kim ),서지원 ( Ji Won Suhr ),신경상 ( Kyoung Sang Shin ),정성수 ( Seong Su Jeong ),박상기 ( Sang Gee Park ),김애경 ( Ae Kyoung Kim ),조해정 ( Hai Jeong Cho ),김주옥 ( Ju Ock Kim ) 대한결핵 및 호흡기학회 1996 Tuberculosis and Respiratory Diseases Vol.43 No.2