기무라씨병의 치험례 -2례 증례보고-

임재호,최재원,김우경,정전은 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.5

Kimura's diseas is a distinct clinico-pathologic entity characterized by proliferation of vascular endothelial cells and lymphoid hyperplasia with florid germinal centers associated with lymphocytic, histiocytic and eosinopholic infiltration. Two cases of Kimura's disease are presented. The first was 53 year-old female patient who had a slow growing mass on right parotid area. The second case was a 25 year-old female patient with two irregular growing masses on both submandibular region. Both cases had markedly increased peripheral eosinophilia with 34% in first case and 31% in second case. The first was treated by superficial parotidectomy and the second by direct surgical excision of masses. The specimens were confirmed ad Kimura's disease on histopathologic examination and the two cases are presented with the review of literature.

K 강선 및 긴장대 강선을 이용한 원위 쇄골 제 2형 골절의 치료

정환용,이우석,전택수,김대환,김광균,임재우 대한골절학회 2003 대한골절학회지 Vol.16 No.2

목 적: 쇄골 윈위부 제 Ⅱ형 골절의 치료에 있어 견봉 쇄골 관절을 통과하지 않고 직접 골편을 고정시키는 K 강선 및 긴장대 강선을 이용한 고정술로 치료한 환자에서 임상 결과를 후향적으로 분석하여 보고하고자 한다. 대상 및 방법: 2000년 5월부터 2001년 5월까지 쇄골 원위부 제 Ⅱ형 골절로 관혈적 정복술 및 K 강선 및 긴장대 강선을 이용한 고정술을 실시한 12례 중 최소 1년 이상 추시가 가능한 11례를 대상으로 하였다. 임상적 평가를 위해 최종 추시에서 변형된 견관절 기능 평가법을 사용하여 결과를 분석하였고 골유합 상태, 합병증, 견관절 운동범위를 측정하였다. 결 과: 전례에서 골유합을 얻었으며, 수술 후 골 유합까지의 기간은 평균 10주 (8~12주)였다. 최종 추시 상 견관절의 운동범위는 모두 정상 소견이었고, 변형된 견관절 기능 평가상 우수 9례, 양호 2례였다. 결 론: 쇄골 원위부 제 Ⅱ형 골절에서 K 강선 및 긴장대 강선을 이용한 고정술은 좋은 치료 방법 중 하나로 사료된다. Purpose: This is retrospective study to analyze the clinical results of the usefulness of K-wires and tension band wiring that fix the fracture fragment directly without passing the acromioclavicular joint in distal clacivle type Ⅱ fractures. Materials and Methods: From May 2000 to May 2001, eleven patients with distal clavicle type Ⅱ fracture were treated by open reduction and internal fixation with K-wires and tension band wiring. The clinical results were analyzed according to modified shoulder rating scale for distal clavicle freacture. Radiological union, complication, and range of motion of the shoulder were assessed. Results: All fractures were united at 10 weeks (8~12 weeks) in average. Finally, full range of motion of the shoulder joint was achieved in all patients. No complication was found and the modified shoulder rating scale for distal clavicle fracture were as follows: excellent 9 and good 2. Conclusion: K-wires and tension band wiring can be a good treatment method for distal clavicle type Ⅱ fractures.

都市地域住民의 生活體育 意識構造

鄭相澤,吳東燮,安禹洪,金正子,林銖遠 慶北大學校 體育科學硏究所 1991 체육과학연구지 Vol.7 No.-

This study was aimed to elucidata Taegu citizens' consciousness about Sport for All. 950 subjects responded to the researcher's questionnaires. The results are as follows; 1) 88.8% of whole subjects felt necessity of physical activity in every day life. In view of sex, 91.0% of male and 86.5% of female felt the necessity. 2) 73.4% of the subjects put weight in health improvement and 19.1% of the subjects put weight in strong mental power in relation to the value of physical activity. 3) About the local facilities of physical activity, only 8.3% of the subjects satisfied. A largy majority(65.7%) of the subjects reveated dissatisfaction. 4) Preference orders in relation to the expansion of facilities appeared as follows; tennis court(24.5%), swimming pool(14.4%), badminton court(12.5%), gymnasium(11.4%) and football field(7.0%). 5) 76.1% of the sujbjects thought that physical activity contribute to reduce demoralized life style, but 3.2% of the subjects not thought so. 6) About present participation in physical activity, 31.8% of the subjects answered being participated, but the large majority(68.2%) of the subjects answered not being participated. 7) Subjects' favorite physical activitier are tennis(18.6%), mounteering (12.9%), football(8.9%), golf(8.6%), badminton(8.3%), jogging(8.3%), gymnasics(7.3%) and swimming(7.0%) 8) The places of physical activities are private facilities(33.4%), work place(13.6%), private house(12.6%), school(10.9%) and physical education park(9.3%). 9) 73.9% of the subjects answered that they were participating in physical activity for health improvement. 10) 70.6% of the subjects felt the necessity of coach of Sport for All. 11) In case of not attendance to the physical activity, 70.6% of them answered that the main reason of not attendance was lack of leisure. 12) In case of not attendance, 33.7% of them spared time to TV watching, 28.8% of them to housework and 18.0% of them to sleeping. 13) 13.5% of subjects wanted to participate in swimming, 12.9% to tennis, 11.7% to table tennis, 10.8% to mountaineering, and 10.3% to badminton if circumstances permit.

Nd:YAG Contact Laser를 이용한 새로운 미세혈관문합술의 실험적 연구

김우경,정전은,박승하,임재호,조진환 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.3

A comparative study was undertaken to evaluate the contact Neodymium : yttrium aluminum garnet(Nd : YAG) laser system for vascular anastomosis of small caliber blood vessels(diameter 0.5-1.2mm) in the animal model. In this study 40 femoral arteries and 40 femoral veins of Sprague-Dawley rats were anastomosed by contact laser assisted microvascular anastomosis(LAMA) utilizing 3 stay sutures which were placed 120 degrees apart and the intervals welded with contact Nd : YAG laser unit, conventionally sutured anastomosis(CSA) served as controls. The time needed for vascular anastomosis, patency rate (immediate postoperative, postoperative 2nd day, postoperative 1 week, postoperative 4 week), gross and microscopic evaluations were compared to conventional microsurgical suture technique. The results are as follows : (1)Post-operative patency rate was 82.5% for femoral artery and 75% for femoral vein by contact LAMA technique compared to 90% and 75% by CSA technique at post operative 4 weeks. (2)Less time-consumed for arterial anastomosis by 6 minutes 23 seconds and venous anastomosis by 8 minutes 55 seconds with contact LAMA technique compared to CSA technique. (3)Grossly almost complete healing had taken place by post-operative 1 week by contact LAMA technique. (4)Aneurysm formation was 5% for femoral artery and 15% for femoral vein by contact LAMA technique compared to 5% and 10% respectively by CSA technique. (5)Microscopically, re-endothelization was complete by post-operative 7th day by contact LAMA technique. There was less medial hypertrophy and hyperplasia and also less inflammatory response compared to CSA.

응집공정에 적합한 In-Line 정적혼화기를 이용한 혼화공정의 개선

정철우,강민수,최시환,정수일,손인식,강임석 대한상하수도학회 2003 상하수도학회지 Vol.17 No.3

The rapid mixing process for coagulation is a critical component in a water treatment plant. However, at the present time a detailed understanding of the rapid mixing by in-line mixer or generally accepted criteria for the design of in-line static mixer are not available. The aim of this work is therefore to improve the understanding of how the in-line static mixer works and how to better utilize it in coagulation process in water treatment. To investigate the performance of static mixer, coagulation experiments were conducted to compare the static mixer to the traditional backmixer under several coagulation conditions. Experiments were also performed to compare the coagulation efficiency of different mixing type of static mixer which were made using different flow rates and the number of elements equipped in a pipe. The static mixer performed better than the backmixer for all coagulation and mixing conditions tested. Especially, the static mixer was very effective in the surface charge neutralization, as showing higher reduction of negative charge with increasing mixing intensity. However, little difference was observed in the performance of the static mixer equipped with 2, 3, and 5 elements. Also, in a series of bench-scale studies of rapid mixing, the in-line static mixer performed better than the traditional backmixer for both adsorption and charge neutralization (A/N) mechanism and sweep coagulation mechanisms. Especially, the static mixer was more efficient at producing A/N mechanism conditions as a result of its fast and uniform dispersion of the coagulant.

좌심방 석회화와 관련된 반복된 좌심방 혈전 1예

김성훈,우성용,오유경,정우백,임철현,신재원,박철수,윤호중,정욱성,홍순조 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.3

실크펩타이드 분말 첨가가 쌀다식의 품질변화에 미치는 영향

김애정,여정숙,우경자,임영희,김미원 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.1

This study was conducted to investigate the effect of added silkpeptide powder on the quality (nutrient content and sensory evaluation score) of the rice Dasik, Rice Dasik was prepared with 0, 1, 2, 3, and 4% concentration of silkpeptide powder. The sensory evaluation scores for the group of the rice Dasik with 2% silkpeptide powder were found to be significantly higher than those of other groups. Increasing silkpeptide powder led to the significant increase in the contents of crude protein and crude ash. But there were no significant differences in contents of crude fat and moisture. And the contents of Ca, K and Mg of silkpeptide powder groups were higher than those of the silkpeptide powder free group.

키보드 형태가 컴퓨터 신경행동검사에 미치는 영향

전만중,김창윤,정종학,임우택,사공준 大韓産業醫學會 2004 대한직업환경의학회지 Vol.16 No.2

목적 : 컴퓨터에 대한 친숙도가 컴퓨터 신경행동검사에 미치는 영향을 평가하고, 컴퓨터 신경행동검사를 수행할 때 키보드 형태의 영향을 평가하며, 컴퓨터에 대한 친숙도와 신경행동검사 결과의 관련성에 키보드 형태의 영향을 평가함으로서 컴퓨터에 대한 친숙도의 영향을 가장 적게 받는 신경행동검사 항목을 선택하고 향후 컴퓨터 신경행동검사를 효과적으로 사용하는데 적합한 키보드의 형태를 결정하기 위하여 수행되었다. 방법 : 컴퓨터에 대한 친숙도는 한글의 분당타자속도에 따라 컴퓨터를 사용한 경험이 전혀 없는 군(1군, 24명, 타자속도 0자/분), 컴퓨터를 사용하긴 하나 익숙지 않은 군(2군, 21명, 타자속도 200자/분 미만) 및 컴퓨터를 능숙하게 다루는 군(3군, 25명, 타자속도 200자/분 이상)으로 나누고 성별, 연령 및 학력을 조사하였다. 신경행동검사는 컴퓨터 신경행동검사 프로그램인 SPES-K를 이용하여 단순반응시간, 숫자더하기, 부호숫자짝짓기 및 손가락 두드리기 순으로 시행하였으며, 일반적으로 컴퓨터에 사용되는 106개의 키를 가진 키보드(1형), 일반적인 키보드를 검사에 사용되는 17개의 키(10개의 숫자키, 4개의 화살표 키, 양쪽 Ctrl키, 스페이스 바)만 두고 나머지 키는 제거한 키보드(2형) 및 11개의 키(10개의 숫자키, 스페이스 바)로 된 특별히 제작된 키보드(3형)를 이용하여 검사하였다. 결과 : 대상자들의 평균 연령은 1군이 49.9세, 2군이 33.6세 및 3군이 28.9세였으며, 각 군간의 유의한 차이가 있었다(F=58.88, p<0.001). 남녀의 구성은 1군, 2군 및 3군에서 유의한 차이가 없었으며, 교육수준은 1군이 평균 10.3년, 2군이 15.3년 및 3군이 17.1년으로 유의한 차이가 있었고(F=39.605, p<0.001), 분당 한글 타수는 1군은 0회, 2군은 평균 79.2회 및 3군은 224.2회였다(F=165.983, p<0.001). 단순반응시간, 숫자더하기, 손가락 두드리기에서 연령과 교육수준을 보정한 평균반응시간과 반응시간의 표준편차 및 오답수는 세 가지 키보드 형태 모두에서 세 군간의 유의한 차이는 없었다. 부호숫자짝짓기에서는 1형 키보드 형태에서 연령과 교육수준을 보정한 후 1군은 3448msec, 2군은 2520msec 및 3군은 2753msec로 1군과 2군 사이에서 유의한 차이가 있었다(F=3.347, p=0.041, Bonferroni F 사후검정). 그러나 2형 키보드 형태나 3형 키보드 형태에서는 세 군간의 유의한 차이가 없었다. 부호숫자짝짓기의 오답수는 연령과 교육수준을 보정한 후 세 가지 키보드 형태 모두에서 세 군간의 유의한 차이가 없었다. 신경행동검사 결과를 한글 타자속도에 따른 각 군내로 한정하여 세 가지 키보드 형태간의 차이를 비교하면 단순반응시간, 숫자더하기 및 손가락 두드리기의 검사 결과는 세 가지 키보드 형태간에 유의한 차이는 없었다. 부호숫자짝짓기의 경우 평균반응시간의 표준편차 및 오답수는 유의한 차이가 없었으나, 평균반응시간이 1군에서 1형 키보드로 검사를 한 경우 4630 msec, 2형 키보드로 검사한 경우 3265 msec 및 3형 키보드로 시행한 경우 3519 msec로 1형 키보드와 2형 키보드간 및 1형 키보드와 3형 키보드간에서 유의한 있었다(F=6.197, p=0.003, Bonferroni F 사후검정). 2군의 경우에는 세 가지 형태의 키보드 간에 유의한 차이가 없었고, 3군의 경우에는 1형 키보드로 검사한 경우 1915 msec, 2형 키보드로 검사한 경우 1761 msec 및 3형 키보드로 시행한 경우 1784 msec로 1형 키보드와 2형 키보드간 및 1형 키보드와 3형 키보드사이에서 유의한 차이가 있었다(F=8.950, p<0.001, Bonferroni F 사후검정). 결론 : 컴퓨터에 대한 친숙도나 키보드에 의한 영향이 많다고 생각되는 근로자 집단에 대해 컴퓨터 신경행동검사를 수행하는 경우에는 단순반응시간, 숫자더하기 및 손가락 두드리기와 같은 검사항목이 다른 검사에 비해 타당성이 좋은 검사로 평가되었다. 그러나 컴퓨터에 대한 친숙도나 키보드 형태에 영향을 받는 부호숫자짝짓기의 경우 대상자의 컴퓨터에 대한 친숙도를 결과의 해석에 고려해야 할 것으로 생각되며, 부호숫자짝짓기의 타당성을 높이기 위해서는 적합한 키보드의 선택에 관한 고려가 필요할 것으로 생각된다. 즉 부호숫자짝짓기의 경우 일반적인 1형 키보드에 비해 컴퓨터에 대한 친숙도의 영향을 감소시키는 경향을 보인 2형과 3형의 키보드 사용이 권고된다. Objectives: A stratified cross-over study was conducted to evaluate the effects of familiarity with computer on the performance of computerized neurobehavioral tests. Effects of keyboard type on the relationship between familiarity with computer and performance of computerized neurobehavioral tests were also examined. Methods: We tested 70 persons classified into three groups according to degree of familiarity with computer: Group 1 was people with no computer competency, Group 2 had slight working experience on the computer, and Group 3 were highly competent and efficient on the computer. For each group, we executed 4 tests of the Korean version of the Swedish Performance Evaluation System (Simple Reaction Time, Addition, Symbol Digit, and Finger Tapping Speed). Three types of keyboard were applied for all three groups. Type 1 keyboard was a conventional layout with 106 keys. We removed the unused keys except for the 17 which were used in the test and remodeled the normal keyboard into Type 2 keyboard with 17 keys (10 numeric keys, 4 arrow keys, space bar, and both CM keys). Type 3 keyboard with 11 keys consisted of 10 numeric keys and the space bas was newly developed for the computerized neurobehavioral performance test. Results: It was found that Simple Reaction Time, Addition, and Finger Tapping Speed were not affected by familiarity with computer and type of keyboard. The mean reaction time of Symbol Digit adjusted by age and educational level with Type 1 keyboard was found to have significant difference among the three groups (F=3.347, p=0.041). The performance of Symbol Digit in Group 1 was found to be significantly lower than that in Group 2. The performances of Symbol Digit measured with Types 2 and 3 keyboards were not found to have significant differences among the thee groups. In Groups 1 and 3, the performances of Symbol Digit measured with Type 1 keyboard were found to be significantly lower than those of other keyboards. Conclusions: According to the above results, Simple Reaction Time, Addition, and Finger Tapping Speed have high priority over other neurobehavioral tests for the workers having varying degrees of computer familiarity. It is also suggested that familiarity with computer and keyboard type needs to be considered in interpretation of the performance of Symbol Digit. We recommended executing the computerized neurobehavioral test with keyboards 2 or 3 to reduce the effect of computer familiarity.

퉁퉁마디로부터 염에 의하여 유도되는 Aldolase 유전자의 분리 및 발현분석

차준영,네티 엘마와티,김순길,이증주,임채오,정우식,이곤호,손대영 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Soil salinity is one of the most serious abiotic stresses limiting the productivity of agricultural crops. To cope with salt stress, plants respond with physiological, developmental and biochemical changes, including the synthesis of a number of proteins and the induction of gene expression. Salicornia herbacea is a halophytic plant that grows in salt marches and on muddy seashores. In order to understand the biochemical and molecular mechanisms of salt tolerance in S. herbacea, we isolated several genes that involved in the salt tolerance by mRNA differential display.Here we report the cloning of a cDNA encoding fructose-1, 6-bisphosphate aldolase, named ShADL, which is 1293 bp long and contains an open reading frame consisted of 359 amino acids with calculated molecular mass of 39 kDa. ShADL protein showed 86% identity with Arabidopsis and 78% with aldolase of common ice plant. Northern blot analysis revealed that the transcript of ShADL gene was increased dramatically depending on the NaCI concentrations.

배추 시스테인 단백질 분해 효소 억제 유전자 BCPI-1의 발현과 종자 발아 및 유묘 생장과의 연관성

홍준기,이은영,김정률,양경애,최영주,정우식,김호일,윤대진,이상열,조무제,임체오 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Phytocystatins are protein inhibitors of cysteine proteinases of the papain family that have been identified in both monocot and dicot plants. A cDNA encoding a phytocystatin, BCPI-1 (Brassica Cysteine Proteinase Inhibitor-1) has been isolated from Chinese cabbage (Brassica campestris L. ssp. pekinensis) flower buds. Here, we tested whether BCPI-1 transcription is regulated by hormones, and could be involved in regulating cysteine proteinases during and after germination. BCPI-1 was sensitive to exogenous GA_(3) and ABA, which are important factors controlling seed germination, suggesting that the expression of BCPI-1 is hormonally regulated. We introduced a recombinant plasmid containing the full-length BCPI-1 cDNA under the control of cauliflower mosaic virus 35S promoter into rice embryogenic calli using the particle delivery method, and regenerated a number of transgenic rice plants. Constitutively over-expressed BCPI-1 caused changes in overall plant growth and development, including reduced germination and seedling growth. These data support the role of the BCPI-1 in the regulation of endogenous proteinases during both seed germination and subsequent seedling development. Phylocystatins은 papain계열의 cysteine 단백질 분해 효소 활성을 특이적으로 억제하는 억제자로 다양한 식물 종으로부터 분리되었다. 본고에서는, 배추 화아 cDNA library로부터 분리된 phytocystatin인 BCPI-1(Brassica Cysteine Proteinase Inhibitor-1)의 생체 내 기능에 대해 연구하였다. 먼저, BCPI-1 전사체는 발아 조절에 중요한 영향을 미치는 GA₃와 ABA에 의해 예민하게 증가, 혹은 감소되는 반응을 보임으로써, BCPI-1이 식물 호르몬의 영향을 받으며, 특히 발아나 유묘의 생장 조절에 관련이 있음을 알 수 있었다. Particle bombardment 방법을 통하여 BCPI-1을 벼의 배 형성 세포 내에 도입, 재분화 시켜 형질 전환 벼를 생성하였다. CaMV 35S promoter의 조절에 의해 지속적인 BCPI-1 발현을 보이는 형질 전환 벼의 경우, 발아와 유묘 생장이 현저히 지연되었다. 위의 결과들을 바탕으로, BCPI-1이 식물체 내에서 생성되는 cysteine 계열의 단밸질 분해 효소 활성을 조절하여 종자의 발아와 유묘의 생장에 영향을 미치는 것으로 추측한다.