Application of Antioxidant Transgenic Mice

Sun?Uk Kim,Hee-Young Yang,Sun-Hee Ahn,Suhee Kim,Dae?Yeul Yu,Dong?Seok Lee,Tae-Hoon Lee 한국실험동물학회 2014 한국실험동물학회 학술발표대회 논문집 Vol.2014 No.8

韓國産 蓼(여뀌)科 植物에 관한 本草學的 硏究 (I)

柳泓善,宋昊埈,辛民敎,金裕鎭,金台晛 한국전통의학연구소 1998 한국전통의학지 Vol.8 No.2

For the purpose of developing Korean Herbalogy with the plants of Polygonaceae which grow wild and is planted in Korea, the these and writings on herbalogy, from literature of successive generations, have been thoroughly investigative and the results obtained were as follows: 1. There were totaled to 16 genera and 156 species in Korea and among them medicinal plants are 12 genera, 47 species, some 30% in total, but the number of species may be added because of the similiar plants. 2. According to the oriental names which can be used for medical purpose, the medicinal plants belonging to the Polygonaceae family were classified as Herba 21, Radix 12, Foilum 8, Lignum 5, Flos 4, Fructus 5, Ramulus 2 and Semen 1. Thus it was noticed that Herba was the main kind. 3. According to sum of 156 species in Polygonaceae family, they were classified into Persicaria genera 63, Polygonum genera 23, Rumex genera 22, Bistorta genera 14, Aconogonum genera 6, Fagopyrum genera 5, Bilderdykia genera 4, Amblygonum genera 3, Reynoutria genera 3, Rheum genera 3, Pleuropterus genera 2, Pleuropteropyrum genera 2, Tovara genera 2, Ampelygonum genera 1, Homalocladium genera 1 and Oxyria genera 1. Thus it was noticed that Persicaria genera was the main kind, some 40.3% in total. 4. According to nature and flavour of medicinal plants, they were classified into cold, cool; 23 each, warmth, heat; 11 each, balance 11 and unidentified 5. Thus it was noticed that cold, cool is the main in nature and flavour of medicinal plants. From this result, it was revealed that the plants for medical purpose in Polygonaceae was 30% of the whole, in which HERBA was mostly abundunt and toxic plants was slightly poisonous that it will be used for clinical treatments more easily. It is considered that many experiements and clinical approaches must be continued to use Polygonaceae plants widely.

구조화된 불확실성을 고려한 지능형 외팔보의 강인제어

권대규,방두열,소순선,유기호,이성철 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2003 工學硏究 Vol.34 No.-

This paper presents the robust control of a composite beam using μ-synthesis. The natural frequencies of the composite beam featured by a piezo-film sensor and piezo-ceramic actuator are calculated by using the modal analysis method and then modal coordinates are introduced to obtain the state equations of the structural system. Two-natural frequency were considered in the modelling, because robust control theory which has inherent robustness to structured uncertainty is adopted to suppress the transients vibrations of a glass fiber reinforced(GFR) composite beam. A robust controller satisfying the nominal performance and robust performance is designed using μ-synthesis theory based on the structured singular value. Simulations and experiments were carried out with the designed controller and effectiveness of the robust control strategy was verified by results.

파종시기가 다른 일미찰의 등숙 중 호화 특성 비교

김미정, 박효진, 이유영, 김선림, 김정태, 우관식, 권영업, 정일민 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

This study was conducted to investigate the pasting properties of waxy corn ‘Ilmichal’ during ripening with different sowing date. Starch content of Ilmichal was increased as matured (p<0.05). Analysis of pasting properties with waxy corn starch using a rapid visco analyser (RVA) showed linear changes in peak viscosity, trough viscosity, final viscosity, breakdown and consistency according to ripening. There were significantly positive correlation between starch content of Ilmichal and peak viscosity (0.39*), trough viscosity (0.58***), final viscosity (0.58***), and consistency (0.57**). Differential scanning calorimerty (DSC). The enthalpy of gelatinization was increased as ripening. But onset and peak temperature were decreased. There were significantly positive correlation between starch content of Ilmichal and onset temperature (0.44*), peak temperature (0.38*), and completion temperature (0.59***), on the other hand, crude protein content presented significantly negative correlation between completion temperature (-0.41*).

콘택트렌즈 보존 용기 유래 Acanthamoeba lugdunensis KA/L5주의 내공생세균

정동일,공현희,김태호,황미열,유학선,윤호철,설성용 경북대학교 의학연구소 1999 경북대학교병원의학연구소논문집 Vol.3 No.1

콘택트렌즈 보존 용기 유래 가시아메바 KA/L5주의 세포질 내에 존재하는 bacterial endosymbiont(내공생세균)를 투과전자현미경으로 관찰하여 확인하였다. 숙주인 가시아메바 KA/L5주는 형태학적으로 제2군에 속하였고, rDNA PCR-RFLP 결과 A. lugdunensis로 동정되었다. 미토콘드리아 DNA RFLP와 동위효소 분석상 이 충주는 국내 콘택트렌즈 보존용기에서 가장흔히 분리되는 type인 KA/Ll주, 국내 임상 분리주 중 하나인 KA/E2주, 내공생세균을 가지는 것으로 보고된 병원 냉각수 유래 KA/W4주 및 L3a주와 동일하거나 매우 유사한 성적을 보였다. 내공생세균은 약 1.38× 0.507㎛의 크기였고, 아메바 세포질 내에 불규칙하게 분포하고 있었으며. 그 표면에 아메바의 ribosome이 부착되어 있었다. 내공생세균을 둘러싼 lacunae나 막과 같은 구조는 관찰되지 않았다. Legionella 특이 primer를 이용한 효소중합반응(PCR)에서 내공생세균의 염색체 DNA는 증폭되지 않았다. A. lugdunensis의 우리말 이름을 담수가시아메바로 제안한다. Transmission electron microscopy of an Acanthamieba isolate (KA/L5) from a contact lens case revealed bacterial endosymbionts within cytoplasm of the amoebae, The Acanthamoeba isolate belonged to the morphological group II. Based on the polymerase chain reaction (PCR) - restriction fragment length Polymorphism (RFLP) of 18S ribosomal RNA coding DNA (rDNA), the Isolate was identified as A. lugdunensis. Strain typing by isoenzyme analysis using isoelectric focusing (IEF) and mitochondrial (Mt) DNA RFLP revealed that the isolate was closely related with KA/Ll , the most predominant type of isolates from contact lens storage cases, KA/E2, a clinical isolate, KA/W4, preciously reported to host endosymbionts, and L3a strains of A. lugdunensis. The endosymbionts were similar to those of KA/W4 In aspects that they were randomly distributed in both trophozoites and cysts, and were rod-shaped bacteria measuring approximately 1.38x 0.50㎛. But the number of endosymbionts per amoeba was significantly lower than that of KA/W4. They were neither limited by phagosomal membranes nor included In lacunae- like structure.

Cisplatin 병용화학요법시 발생한 오심, 구토에 대한 Ondansetron과 Metoclopramide의 효과에 대한 비교

김미자,국기용,김태원,박유환,김완중,허경,정춘해,홍순표 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Inspite of possible effects for emesis following chemotherapy including cisplatin, nausea and vomiting are the most unpleasant side effects of cancer chemotherapy. None of the currently available antiemetic agents is entirely effective preventing emesis. Ondansetron, a 5-HT(5-hydroxytryptamine)_(3) receptor antagonist, has been shown to be effective antiemetic agent in the control of cisplatin induced emesis. Twenty solid tumor patients who are scheduled to receive cisplatin containing combination chemotherapy participated in a prospectively randomized study to compare the antiemetic efficacy and safety of ondansetron and metoclopramide. Ondansetron was given in dose of 8mg intravenous 30min before cisplatin and then 4hours and 8hours after cisplatin on day 1, and Ⅰ.Ⅴ. every 8hours from day 2 to 5. In the metoclopramide group, metoclopramide was given in dose of 2 ㎎/㎏ intravenous every 8hours from day 1 to 5. The control of emesis was graded in the following way : complete response, no vomiting : major response, 1-2 emetic episodes : minor response, 3-5 emetic episodes : failure, above 5 emetic episodes. Complete or major response of emesis was achieved 10 of 12(83.2%) patients receiving ondansetron and in 5 of 8(62.5%) patients receiving metoclopramide, but effectiveness was not significantly different. Ondansetron was at least as effective as metoclopramide therapy in controlling cisplatin induced emesis. Side effects in ondansetron was less than in Metoclopramide.

광중합기의 광원에 따른 브라켓 전단결합강도 비교

차정열,이기준,박선형,김태원,유형석 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.3

제논 플라즈마 아크 광중합기나 LED 광중합기가 치과영역에 소개된 이후로 기존의 텅스텐 할로겐 광중합기를 사용할 때에 비해 교정장치의 부착시간이 현저하게 줄어들 수 있게 되었다. 제논 플라즈마 아크 광중합기에 대한 중합시간과 전단강도에 대해서는 여러 연구가 있어왔던 반면, LED 광중합기를 이용하여 교정용장치의 부착을 위한 중합시간에 대한 연구는 미진하다. 본 연구의 목적은 LED 광중합기의 중합시간에 따른 결합강도를 플라즈마 아크 광중합기와 비교하여 적절한 브라켓의 부착강도를 얻기 위해 요구되는 중합시간을 알아보는데 있다. 120개의 발치된 사람의 소구치에 컴포짓 레진으로 브라켓을 부착시킨 후 4초, 6초, 8초 동안 플라즈마 아크 광원과 LED 광원으로 각각 중합시켰다. 그 후 결합강도를 만능시험기(Universal Testing Machine)로 계측한 결과, 플라즈마 아크 광중합기에서는 4초 이상에서, LED 광중합기에서는 8초 이상의 중합시간에서 기존의 할로겐 광원을 40초간 노출시켰을 때와 비슷한 전단결합강도를 나타내었다. 플라즈마 아크 광중합기와 LED 광중합기의 중합시간이 접착제 잔류지수(adhesive remnant index) 수치에 대해 영향을 미치지 않았다. With the introduction of the xenon plasma arc curing light and the LED curing light as orthodontic curing lights, the polymerizing time of orthodontic composites has clearly decreased. In contrast to various research cases regarding the polymerization time and bond strength of the xenon plasma arc curing light, not enough research exists on the LED curing light, including the appropriate polymerization time. The objective of this research was to compare the bond strength of the plasma curing light and the LED curing light in regards to the polymerization time. The polymerization time needed to achieve an appropriate adhesion strength of the bracket has also been studied. After applying orthodontic brackets using composite resin onto 120 human premolars, the plasma arc curing light and the LED curing light were used for polymerization for 4, 6, and 8 seconds accordingly. This research proved that the LED curing light provided appropriate bond strength for mounting orthodontic brackets even with short seconds of polymerization. The expensive cost and large size of the device limits the use of the plasma arc curing light, whereas the low cost and easy handling of the LED curing light may lead to greater use in orthodontics.

유색미에 관한 연구 : Ⅲ. 유색미 유망계통에 대한 주요 생육 특성

김광수,최윤표,김선택,최현구,정종태,김보경,유지홍,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2

국내외 유색미 수집종을 돌연변이원에 의해 유기된 우수 계통과 수집종간 상호교배에 의해 선발된 CNU 20계통을 파종하여 얻어진 주요 작물학적 특성을 살펴보면 다음과 같다. 1. 간장은 유색 메벼인 CNU126 계통이 대조품종인 동진벼와 같이 가장 컸고 메성인 CNU 128계통에서 가장 작았다. 2. 주당 분얼수는 CNU3, CNU50. CNU56, CNU112 계통에서 가장 많았고 대조품종과 CNU 128 계통에서 10개 미만으로 가장 적게 나타났다. 3. 수장은 육성 계통 중 CNU88 계통에서 가장 길었으나 대조구보다 짧고, 육성계통 중에서는 CNU 126 계통이 가장 짧았다. 4. 주당 영화수는 대조구인 동진벼보다 CNU50 계통에서 2배 이상 많았고, CNU158 계통에서 가장 적게 나타났다. 5. 천립중은 CNU113 계통에서 30g이상으로 대조구와 같이 가장 무거웠고, CNU128 계통에서 20g으로 가장 적었다. 6. 주당 수량은 대조구의 26.6g에 비해 CNU50, CNU112 계통에서 두배정도 높았고, CNU128, CNU158, CNU200 계통에서 가장 낮게 타나났다. Aims of this study were carried out to develop the useful lines induced from mutation and pedigree breeding methods among the collected genetic resources from national and domestic areas. In this study, Stem height of CNU126 line and check among them were high, while CNU128 was lower than other lines. Spiklet length of CNU88 was longer, but that of CNU126 was shorter than check. Number of spiklets per plant of CNU50 among lines have twice time than check. 1,000 grains weight of CNU113 was higher than check. In yield per plant, CNU50 and CNU112 were higher than check, Dongjinbyeo.

Outcomes of Rate-Control Treatment in Patients With Atrial Fibrillation and Heart Failure — A Nationwide Cohort Study —

Yu, Hee Tae,Yang, Pil-Sung,Lee, Hancheol,You, Seng Chan,Kim, Tae-Hoon,Uhm, Jae-Sun,Kim, Jong-Youn,Pak, Hui-Nam,Lee, Moon-Hyoung,652, Boyoung Joung UNKNOWN 2018 CIRCULATION JOURNAL Vol.82 No.3

<P>Conclusions: Use of beta-blockers was associated with a reduced mortality rate for AF patient with HF but not for those without HF. These findings should be examined in a large randomized trial.</P>

Poor Rhythm Outcome of Catheter Ablation for Early-Onset Atrial Fibrillation in Women — Mechanistic Insight —

Yu, Hee Tae,Yang, Pil-Sung,Kim, Tae-Hoon,Uhm, Jae-Sun,Kim, Jong-Youn,Joung, Boyoung,Lee, Moon-Hyoung,Pak, Hui-Nam UNKNOWN 2018 CIRCULATION JOURNAL Vol.82 No.9