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박승국,허정욱,강영우,안성훈,이상곤 啓明大學校 醫科大學 1993 계명의대학술지 Vol.12 No.2
저자들은 1981년부터 1990년사이에 64,207명을 대상으로 내시경검사를 시행하여 8,814명에서 소화성궤양을 진단하여 다음과 같은 결론을 얻었다. 소화성궤양의 발생률은 13.7%였다. 위궤양과 십이지장궤양의 발생비는 1981년에는 1:0.9였으나 그후로는 1:1.1-1:1.5로 십이지장궤양의 발생비율이 높았다. 발생비율을 남녀별로 보면 위궤양의 경우에는 약 4:1 십이지장궤양은 3:1로 남자에서 많았다. 연령별로는 위궤양은 40대, 50대, 60대의 순서였고, 십이지장궤양은 30대, 40대, 20대 순으로 호발하였다. 위궤양은 위체부에서 대부분 발생하였다. In this century, very striking changes in incidence and prevalence of peptic ulcers, as well as in sexual proportion, in the age of the affected population and in the proportion of duodenal to gastric ulcers had occured and these epidemiological changes are ongoing. Therefore, we reviewed 8,814 cases with endoscopically proven peptic ulcers from 1981 to 1990. The results obtained are as follows; The prevalence of peptic ulcers among patients received endoscopy was 13.7%. The ratio of peptic ulcers among patients received endoscopy was 13.7%. The ratio of gastric ulcer to duodenal ulcer was 1: 0.9 in 1981, but after then the propotion of duodenal ulcer was higher in 1: 1.1-1:1.5. The ratio of male to female was about 4:1 in gastric ulcer and 3:1 in duodenal ulcer. The prevalence of gastric ulcer was highest in foruth decade and then fifth and sixth in order and the prevalence of duodenal ulcer was highest in thrid decade and then fourth and second decade in order. Most of the gastric ulcers were found at the gastric body.
주산기 백서에서 혈중 에스트로겐 농도와 공간 기억력과의 상관관계
박민성,박제민,신성현,한귀원,김명정,김성곤 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.5
Objectives : This study was designed to find possible effect of pregnancy and parturition on spatial memory, especially in relation to levels of estrogen during the third trimester and postpartal period in rats. Methods : 25 female Sprague Dawley rats were divided into pregnant group (N= 14) and control group (N= 11). Changes in spatial memory during 6 weeks including third trimester and postpartal period were measured using Morris water maze. Time to reach the platform in the maze was indicator of spatial memory. Serum estrogen level was measured on 1 week before delivery, postpartal day 1, and day 14. Results : Both groups showed gradual improvement in performance by trial days and weeks, but no significant difference was found between the two groups. However in the third trimester, pregnant group showed a trend of less achievement on 3 days of learning than control group. Serum estrogen levels did not differ significantly between groups over the 6 weeks of period. However there was positive correlation between serum estrogen level on postpartum day 1 and time to reach platform on postpartum week 2, and negative correlation between estrogen level on postpartum day 14 and latency to the platform on postpartum week 5. Conclusion : These results imply that changes in the serum estrogen level may have dual effects on the spatial learning in peripartal period. It is suggested that decline in cognitive function might occur either by failure of rapid decrease of estrogen, immediately after parturition, or retarded restoration of estrogen in later postpartal period.
박치영,강지은,박상곤,김상현,김형선,정춘해 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2
Background: Autoimmune hemolytic anemia (AIHA) is a very uncommon disorder with the incidence between one and three cases per a hundred thousans a year. There have been very few studies about AIHA in Korea because of its low incidence. Most AIHA studies in Korea were about case history. The aim of this study was to review the clinical features, therapy and outcome of AIHA patients in single institution clinic. Methods: We reviewed retrospectively the medical records of AIHA patients from December 2002 to December 2006. Results: Twelve patient with AIHA were identified, and their median age was 49 years (range 27-75). Male to female ratio is 9:3. The median hemoglobin level was 5.0 g/㎗ (range 2.5-8.2). Warm type AIHA was most common (8/12), cold type was three, and mixed type was one. There was histories of associated disease in six patients. Two patients were complicated by systemic lupus erythematosus and mycoplasma infection and one patient by idiopathic myelofibrosis and solid tumor. Oral steroid was used as the first-line treatment in nine patients. An initial response was observed in eight patients with complete response. One patient had not responded to the initial steroid treatment, and then showed complete response with rituximab. Two relapsed patients were treated with rituximab and partial splenic embolization. Conclusion: The majority of patients can be treated with steroid. Rituximab can improve the response rate in relapsed and refractory AIHA.
Thermal MOCVD와 DC pulsed PA-MOCVD에 의해 증착된 TiN 박막 연구
박용균,이영섭,이태수,이성재,조동율,천희곤 울산대학교 2001 공학연구논문집 Vol.32 No.1
유기화합물(TDEAT;Ti[N(C2H5)2]4)과 NH3를 이용하여 thermal MOCVD와 dc pulsed plasma assisted MOCVD(PA-MOCVD)인 2종류의 TiN박막을 증착하여 비교하였다. TiN박막의 특성분석은 XRD, AES, FE-SEM, α-step과 XPS로 연구하였다. DC pulsed plasma assisted MOCVD로 증착된 Tin박막은 ion bombardment 효과에 의해 열적으로 증착된 것보다 더 fine한 columnar구조를 나타내므로써 막의 결정질이 향상되었다. 플라즈마에서의 아르곤 이온의 충돌로 인해 탄소(C)는 오히려 유기 화합물보다 탄소 라디칼로 존재하였다. 따라서 탄소 라디갈은 기판의 강한 (-) potential에 의해 TiN박막에 trap되기 때문에 탄소(C)는 열적으로 증착된 TiN박막보다 더 많은 양이 존재하는 것으로 추정된다. By using of (TDEAT;Ti[N(C2H5)2]4)and ammonia gas source, we deposited two different TiN thin films with thermal MOCVD and dc pulsed plasma assisted MOCVD (PA-MOCVB). The properties of TiN thin films were studied by XRD, AES, FE - SEM, α - step and XPS analyses in this work. The TiN films deposited by dc pulsed PA - MOCVD have a little higher density and a fine columnar structure, compared with thermally deposited TiN thin films. This may be due to ion bombardment effect resulting in improved crystallinity in films. Carbon in the film may exist in the form of carbonic radical rather than organic compound because of collision with Ar ion in the plasma. Consequently, the content of carbon in the film of dc pulsed PA - MOCVD was higher than that in thermally deposited TiN films, because carbon radicals could be trapped in the film by strong negative potential of the substrate.
박선국,이상관,최부귀,하홍곤 동아대학교 공과대학 부설 한국자원개발연구소 1991 硏究報告 Vol.15 No.1
The dynamics of the Multi―degree of freedom manipulator is highly nonlinear and the compensation against this nonlinearity should be indispensable. This paper proposes the decentralized joint control method based on the distrubance observer where the dynamical equation is not directly solved. This system has excellent performance of disturbance supression, because the total acceleration including the load torque and various kinds of frictional torques can be controlled directly, come experiments show the effectiveness of the proposed system. This paper discuss the important relationships with the feedforward compensation type Servo system using distrubance torque observer.