물질남용 치료프로그램 후 재범여부에 대한 예비적 추적조사 연구

김현수,조선미,오은영,임기영,정영기,윤웅장,이영미 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.6

연구목적: 본 연구는 물질사범에게 시행되는 수강명령 프로그램의 효과를 재범률을 중심으로 살펴보고자 한 것이다. 방 법: 이 연구의 대상집단은 보호관찰소에서 의뢰받은 물질남용자집단이다. 이들은 법원으로부터 보호관찰, 수강명령, 치료명령, 사회봉사 등을 부과받았다. 총 104명의 대상자집단을 치료프로그램을 이수한 수강군과 비수강군으로 나누었으며 이들에 대한 재범률을 조사하였다. 결 과: 프로그램을 이수한 수강군이 비수강군에 비해 재범률이 낮았다(p<.05). 또한 단기 수강군과 장기수강군의 재범률의 차이를 조사하였는데 대상자 집단의 수가 적기 때문에 장기 수강군의 효과가 통계적으로 입증되지는 않았다. 결 론: 우리는 물질남용자에 대한 정책이 보다 교육적으로 변화할 것을 본 논문을 통하여 제시하려 하였으며 정부 및 법무부는 물질남용자에게 교육과 치료를 제공해주어야만 한다. Objectives: Using recidivism rate, we investigated the outcome after our substance abuse treatment program had been implemented. Methods: Our target population was substance abuse criminals referred by probational office. They either received the parole and probation order, treatment order or social service order from the court. We divided 104 substance abuse criminals into treatment group and non-treatment group. We examined their recidivism rate. Results: We reached a conclusion that treatment group had lower recidivism rate than non-treatment group(p<.0.5). We examined the effectiveness of short-term and long-term programs. However, no effectivess of long-term program was found because the sabject number was too small. Conclusion: We suggest that the strategies for substance abuse should be changed to more educative ones. The Government and Ministry of Justice must provide education and treatment to the substance abuse criminals.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

박물관 관람자의 동선특성에 관한 조사

임채진,한선영 홍익대학교 산업디자인 연구소 1999 미술디자인 논문집 Vol.- No.4

The purpose of this study is to analyze the characteristics of exhibition circulation through the movement pattern. It looks into the factors under the influence with the visitor's movement. The method of analysis is statistics of investigation by following after visitors. The viewing behavioral of exhibition based on the time, speed, proportion of appreciation is classified into three types of the profound, the general, the passing viewers. The characteristics of the viewing form of these patterns largely depend on the space elements which are the structure form. And particularly the position of exit, the width of exhibition space and the connection of exhibition space stand out the disparity of the factor of the spatial structure. These three patterns bring about a lot of encounter in the exhibition space according to the difference of these routes consequently. So appropriate to the planning of each pattern can offer visitors to more effective environment of exhibition.

의류제품 판매원 유형 분석(제1보) : 대구지역 의류매장을 중심으로

임선영,김정원 한국의류학회 1998 한국의류학회지 Vol.22 No.3

The purpose of this study was to classify the types of salespeople in the apparel stores. A questionnaire was administered to 267 fashion sales related persons in apparel store in downtown, Daegu. Data were analyzed by using frequency, X^2-test, cluster analysis, MANOVA, ANOVA and Duncan test by using J.M.P(v.2.01) Mac. program and SAS for windows(v. 6.02) PC program. The results of this study were as follows: The types of salespeople were classified into 4 types: "complaining type as a salespeople", "sensitive type for other affairs than their duty", "satisfying as a salespeople" and "performance reaction type". There were significant differences in academic background, selling apparel type/apparel store type, and in all factors in job satisfaction/dissatisfaction, attitude toward working condition, customer type, and selling training by the different types of salespeople. Complaining type as a salespeople were dissatisfied with most items related with job attitude and showed negative response as salespeople. Sensitive type for other affairs than their duty responded more keenly to other affairs than their duty and showed the highest dissatisfaction on the job dissatisfaction factors, and showed the most emotional reaction on attitude toward working condition, customer type, and regulation. Satisfying type as salespeople showed the positive and active attitude for their job. Performance reaction type were satisfied with their job as salespeople only when their performance is tangible as sales increases and showed highest satisfaction only on the job satisfaction factors. The necessity of professional training was shown in all types of salespeople.

한국기업의 국제화에 따른 대응전략

임순철,윤영한 청주대학교 대학원 1997 우암논총 Vol.18 No.-

남북의 문화 사상 교류의 방향

임규정,박순영 군산대학교 현대이념연구소 1998 現代理念硏究 Vol.13 No.-

All-Trans Retinoic Acid에 의한 HL-60 세포 분화유도중 H2B Histone, c-Myc 및 DNA Topoisomerase I 발현에 관한 연구

임규,박정동,최병한,이용진,김계영,이명선,장은미,김삼용,권기량,곽상태,황병두 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

Effects of all-trans retinoic acid(retinoic acid) on DNA replication, H2B histone and DNA topoisopmerase I(Topo I) gene expression have been investigated in human promyelocytic leukemia cell line HL-60. DNA synthesis decreased at 24 hours after exposure of retinoic acid in the HL-60 cells. H2B histone mRNA rapidly reduced at 48 hours and Topo I and c-myc mRNA at 24 hours in retinoic acid-exposured HL-60 cells, respectively. The levels of c-myc, H2B histone and Topo I gene expression were reduced in proportion to the concentration of retinoic acid. The H2B histone mRNA in retinoic acid-exposured cells was elevated by cycloheximide treatment, while the level of Topo I mRNA was constant. These results suggest that regulations of H2B histone, c-myc and Topo I gene expression are different from one another, and repression of Topo I gene is closely correlated with c-myc gene during retinoic acid-induced differentiation of HL-60 cells.

적외선방사카메라를 이용한 변압기 부싱 온도분포 모니터링

임장섭,이우선,이영식 조선대학교 에너지.자원신기술연구소 2002 에너지·자원신기술연구소 논문지 Vol.24 No.2

An electrical accident such as mishap electricity institution occurs frequently because of the increase of demand for electricity, complexity of electricity institution. The techniques that discovered a mishap to electricity institution are electric signal method and supersonic waves method, thermal sensing method by infrared rays. The IRR-camera which is effective monitoring method of electricity institution is diffused in industrial field. Specially, infrared rays monitoring can perceive heat which was visually poor observed objection. Also, infrared rays monitoring can monitor an area of difficulty of access of work human power. In this study, infrared rays monitoring of a transformer substation is periodically performed. The connection between possibility of application and operation, blazing fire occurrence and progress process of body and bushing of large capacity transformer are performed by IRR-camera.

염화수소(Hydrogen Chloride)와 관련성이 추정되는 직업성 천식 1례

임현술,유선희,김두희,이영현 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

염화수소(hydrogen chloride)는 분자식은 HCl이며 염산가스라고 불리기도 하며 강한 자극성 냄새가 나는 무색의 기체이다. 물에 녹아서 염산이 되며 공기 중에서 물에 녹기 쉬운 성질 때문에 연무 형태로 존재한다. 본 증례로 34세 남자로 타이어에 사용되는 철사를 제조하는 공장에 다니는 근로자로 간헐적으로 고농도의 염화수소에 폭로된 후 1년 8개월의 잠복기를 거친 후 기관지 천식이 발생한 예로 총 호산구수는 증가되어 있었으나 혈청 IgE는 정상 범위였다. 55가지 알레르기항원을 사용한 피부 단자검사에서 House dust, Hay dust, Mixed grain, Dermatophagoides farinae와 Dermatophagoides pterynyssinus에 양성 반응을 보였고, 유발검사에서는 양성 반응을 보였다. 직업성 여부를 파악하기 위해 작업장 내에서 8시간 동안 근무하면서 30분 내지 한시간 간격으로 폐기능검사를 시행한 결과 1초간 노력성 호기량(FEV1) 이 20%이상 감소하여 2시간 동안 지속되는 양성 반응을 관찰할 수 있었다. 본 증례는 외인성 천식 소질이 있으면서 작업장 내에서 고농도의 염산증기에 폭로되어 기관지 천식 발작이 되었는데, 작업장의 고농도의 염화수소가 기관지 천식의 기여요인 또는 악화요인으로 작용하였다고 생각한다. Occupational asthma is an importent occupation-related disease. We exprienced a case of asthma induced by high concentration of hydrogen chloride vapour. The prevalence rate of this asthma is unknown. The patient of the case complained of cough, sputum and dyspnea after exposure to hydrogen chloride. Serum IgE(IgE-PRIST) was normal range but total eosinophil count was elevated. FEV₁ was 73% of predicted value and expiratory wheezing sound was observed on whole lung field. FEV₂was decreased to 48.9% of baseline on 5 hours 30 minutes, respectively, after exposure of hydrogen chloride at workplace. On follow up examination, the patient complained of an intermittent dyspnea and cough.

한국판 섬망 평가 척도-98(K-DRS-98)의 표준화 연구

임경옥,김수영,이양현,이선우,김정란 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.6

Objective : This study was conducted to develop and to validate the Korean version of Delirium Rating Scale-Revised-98(K-DRS-98), which is a scale for diagnosing delirium and evaluating its severity. Method : After developing the K-DRS-98, 102 patients were rated by it among 4 diagnostic groups, such as delirium (N=25), dementia (N=27), schizophrenia (N=25) and others (N=25). To test for reliability, K-DRS-98 was independently administered by two psychiatrist. To test for validity, Korean version of Mini-Mental State Examination (MMSE-K) and Clinical Global Impression (CGI) were administered simultaneously. Statistical analysis was done with SPSS window version 12 package and statistical significance was p<0.05. Result : Intemal consistencies (Cronbach α) of two raters were 0.867 and 0.858, respectively. Inter-rater reliability (κ) was 0.893 for severity items of K-DRS-98 and κ value of diagnosis items was 0.969. In Delirium group, Pearson correlation Coefficients (r) of K-DRS-98 were -0.682 for MMSE-K and 0.667 for CGI. In comparison Delirium group with Others, ANOVA post hoc multiple comparison LSD was statistically significant (p<0.001). The cutoff score to diagnosis of delirium can be recommended 16 for seventy items and 21.5 for total score, respectively. Conclusion : The K-DRS-98 was showed good reliability and validity for the assessment of delirium. The K-DRS-98 is an easy and useful tool for diagnosing delirium and assessing its severity.