외음부의 기저세포암

김보영 ( Bo Young Kim ),황선정 ( Sun Jung Hwang ),박병준 ( Byung Joon Park ),이은실 ( Eun Sil Lee ),한호섭 ( Ho Suap Han ),김용욱 ( Yong Wook Kim ),김태응 ( Tae Eung Kim ),노덕영 ( Duck Yeong Ro ),이안희 ( An Hi Lee ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.9

Basal cell carcinoma (BCC) is the most common human malignant neoplasm, accounting for 75% of all non-melanoma skin cancer. The incidence of BCC is strongly correlated with sun exposure as well as older age. Therefore, the vast majority of BCCs is observed in elderly patients on the sun-exposed skin of the head and neck with a frequency of more than 80%. BCC is very rare on sun-protected skin such as the perianal and genital regions and other etiologic factors must be considered in these cases. Although the pathogenesis of vulvar BCC is unclear, early diagnosis is very important. Because BCC in these areas sometimes seems innocuous, it is recommended that a biopsy of all suspect lesions be performed. We report a woman with BCC of the vulva treated with wide local resection and reviews the literatures on this subject.

Base Emitter Codiffusion 소자 제조 및 전기적 특성 고찰

李善東,金政彦,朴淳太,梁光鎭,洪昌熹 동아대학교 공과대학 부설 한국자원개발연구소 1990 硏究報告 Vol.14 No.2

In the time when we fabricated the NPH bipolar transistor the temperature annealing was needed. Then the properties of transistor was damaged because of inducing the silicon lattice defects. In this paper, proposed codiffusion method was able to control of junction depth by implant energy, dose concentration, diffusing temperature and annealing time control. In addition to, we studied for developed the transistor of high speed switching.

忠淸南北道 國民學校 倂設幼稚園 및 새마을 協同幼兒園 敎育實態에 關한 調査硏究

李善熙,吳英姬 培材大學校 1982 論文集 Vol.3 No.-

There are 241 kindergartens in public schools and 18 Sae Ma Ul co-operative nursery schools at no cost to the parents In Choong Nam province at present (Dec. 1981). There are 98 Kindergartens in public schools and 14 Sae Ma Ul co-operative nursery schools In Choong Buk Province. The purpose of our study is 1. to ascertain the Status of Kindergartens and Sae Ma Ul co-operative nursery schools in Choong Nam and Choong Buk Province. 2. to study the administrative problems of the kindergartens through questionnaires and discussions with kindergarten directors, teachers and parents. 3. to study the back-ground of the process and development of Korea Kindergartens. 4. to make recommendations to the government, Ministry of Education, and to the Educational Association in order to improve early childhood education. The results and our recommendations are as follows: 1. Efficient kindergarten administration 1) Kindergarten children need private class rooms. 2) Substitute teachers need to be trained ahead of time. 3) Most teachers are teaching primary children in the morning and kindergarten children in the afternoon. Because of the physical and emotional demands of the job a person over 50 years old would not be suitable. 4) It would be advisable for teachers to reach only one class, instead of the two, as the job is very strenuous. 5) Provide teachers with the opportunity for advance study through night college or college study during vacations to improve the teachers' qualification. 6) The directors, supervisors, and teachers need to be trained through reeducation and seminars to understand kindergarten education. 7) At the present, there are three different competent authorities for the early childhood education institutions (kindergartens under the Ministry of education, Children's home under the Ministry of Health and Social Affairs, and Sae Ma Ul co-operative nursery schools under the Ministry of Home Affairs) . It is hoped that the competent authorities can be unified. 8) There must be a government school inspector who hat majored in earth childhood education working at the educational Association in each city, county and province. 2. Kindergarten curriculum 1) We need to develop kindergarten curriculum which is suitable for the individual kindergarten. This can be done through research studies by a model kindergarten or early childhood education department at the college level. 2) To provide sample kindergarten materials once or twice a year at an exhibition sponsored by the government. New teaching materials and equipment would be introduced and creative ideas exchanged by the participants. 3. Teaching materials, equipment, and facilities 1) More than 2/3's of the kindergartens and Sae Ma Ul co-operative nursery schools are sub standard in teaching materials, equipment, and facilities. 2) More government subsidies are needed through the new Education tax to bring teaching materials, equipment and facilities up to standard and provide quality education for young children. 3) If government subsidies are not enough to provide quality education, the parents gust be charged a small fee according to the situation of the district. We need to solves many problems through continuing research studies and in co-operation with government, teachers and parents to provide the best early childhood education possible for well-rounded children in Korea.

가사노동 관리자유형과 관련 변인에 관한 연구

이선화,채옥희 圓光大學校大學院 1996 論文集 Vol.17 No.-

The purpose of this study is to investigate household work manager style and it's related variables. The subjects of this study were 111 homemakers living in Ik-San. Survey methods were qustionnaire. Data analysis strategies were percentile, frequency, and X2 - test. Following are the results: 1. The characteristics of management in household work have the person orientation. 2. Household work manager style exhibit the related style in his study. The related style is higher the person orientation than the task orientation. 3. Household work manager styles exhibit different in socio-demographic variable such as homemaker's job. Employed wives show the dedicated style but full-time homemakers show the seperated style.

하시모트 갑상선염과 동반된 갑상선 MALT 림프종(MALToma) 1 예

김영선,이태영,한찬희,유명희,김철희,변동원,진소영,남일송,류은상,홍기영,윤석기,서교일 대한내과학회 2001 대한내과학회지 Vol.61 No.3

Primary thyroid lymphomas constitute of up to 5% of all thyroid malignancies. Recently, mucosa-associated lymphoid tissue (MALT) lymphoma are relatively recognized as a B cell subset of non-Hodgkin's lymphoma. MALT-lymphomas are thought to develop from acquired lymphocytic tissue during the course of a chronic inflammatory or autoimmune process. In the thyroid , which is normally devoid of lymphocytic tissue, chronic autoimmune thyroiditis (Hashimoto's disease) has been associated with an increased risk of lymphoma, including MALT type. The clinical presentations include the enlarging of the neck mass, dysphagia, hoarsenes and choking or cold thyroid nodule. We report a case of MALToma of the thyroid accompanied by Hashimoto's thyroiditis with a review of the literature.(Korean J Med 61:281-285, 2001)

인삼엽의 엽록체발달과 CO2 고정양상에 관한 연구

이순희,조영동,홍영남,권영명 ( Sun Hi Lee,Young Dong Cho,Young Nam Hong,Young Myung Kwon ) 생화학분자생물학회 1982 BMB Reports Vol.15 No.2

Development of chloroplast, ability of CO₂-fixation, photosynthetic early intermediates and activities of catalase and glycolate oxidase were observed during greening process. Such results were discussed with the formation of CP-complex. The phenomenon of chloroplast development was similar to other plants, but the rate of process was relatively slow, and ability of CO₂-fixation was slow accordingly. The increase in chlorophyll was observed after more than 12 hours illumination. Such results were paralleled with the formation of CP-complex in thylakoid membrane. Considering the low ability of CO₂-fixation compared with that of other sun-plants, different photosynthetic intermediates at early period, and activities of both glycolate oxidase and catalase, ginseng is more likely to be C₃-plant.

항갑상선제로 치료한 그레이브스병 환자의 관해예측인자

남일송,윤여일,김선규,김용현,이주영,목지오,윤석기,김철희,김영선,변동원,서교일,유명희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: Most cases of Graves' disease have been treated by antithyroid drugs in Korea. The major drawbacks of antithyroid drugs are the relative high rate of relapse and the inconvinience of long term therapy. Measurement of TBII and TRH stimulation test have been considered as the most reliable tests predicting relapse, but the predictive power is not high enough to use in clinical situation. This study was performed to find good prognostic indicators in Graves' disease patients after the discontinuation of antithyroid drug therapy. Subjects and methods : We restrospectively evaluated 96 patients with Graves' disease who showed normal TRH test at the end of antithyroid drug therapy and were followed for more than one year. Serum T3, T4, T3/T4 ratio, TBII, Anti-TPO Ab and TGAb levels were measured at the time of diagnosis and at the end of therapy. Two to three months after withdrawal of antithyroid medication, serum TSH and free T3 responses to TRH were examined. These parameters were compared between the relapse group and the remission group. Results : Among the 96 patients, 22 patients(22.9%) relapsed(Group Ⅱ) and 74 patients(77.1%) remained in remmision(Group Ⅰ). No significant difference was observed between the relapse and the remission group in clinical parameters, serum T3, T4, TSH, T3/T4 ratio, TBⅡ and Anti-TPO Ab determined before and after treatment. Serum TSH and free T3 levels measured after TRH stimulation were also similar in both groups. Serum TGAb levels determined at the end of treatment were significantly higher in the remission group(p<0.05). Relapse following the discontinuation of therapy occured within 24 months in 72.7% of the relapsed cases. After 24 months, relapse rate was reduced significantly. Conclusion : These results suggest that high serum TGAb levels could be a favorable prognostic indicator for the long term remission of Graves' disease treated with antithyroid drugs, and may suggest that Hashimoto's thyroiditis is combined with Graves' disease in those patients.

인삼엽(人蔘葉)의 엽록체발달(葉綠體發達)과 $CO_2$ 고정양상(固定樣相)에 관한 연구(硏究)

이순희,조영동,홍영남,권영명,Lee, Sun-Hi,Cho, Young-Dong,Hong, Young-Nam,Kwon, Young-Myung 생화학분자생물학회 1982 한국생화학회지 Vol.15 No.2

인삼엽의 greening과정중 엽록체발달(葉綠體發達), $CO_2$ 고정능(固定能), 초기(初期) 광합성(光合成) 중간대사산물(中間代謝産物), catalase와 glycolate oxidase 활성등을 조사(調査)하였고, 이러한 결과(結果)들은 CP-complex의 생성(生成)과 연관시켜 논의(論議)하였다. 엽록체발달양상(葉綠體發達樣相)은 타식물(他植物)과 같았으나 그 과정(過程)이 비교적 느렸고, 따라서 $CO_2$고정능(固定能)도 느렸다. 12시간 이상(以上) 빛을 조사(照射)하여야 엽록소양(量)이 증가하였다. 이러한 결과(結果)는 엽록체발달(葉綠體發達)에 따라 thylakoid막(膜)에서 CP-cmplex의 생성(生成)의 증가와 일치하였다. $CO_2$고정능(固定能)은 다른 양지식물(陽地植物)에 비하여 훨씬 낮았으며, 초기(初期) 광합성(光合成) 중간대사산물(中間代謝産物)의 변이(變異)와 glycolate oxidase 및 catalase 등의 활성(活性)으로 보아 인삼은 $C_3$-plant임을 추정할 수 있었다. Development of chloroplast, ability of $CO_2$-fixation, photosynthetic early intermediates and activities of catalase and glycolate oxidase were observed during greening process. Such results were discussed with the formation of CP-complex. The phenomenon of chloroplast development was similar to other plants, but the rate of process was relatively slow, and ability of $CO_2$-fixation was slow accordingly. The increase in chlorophyll was observed after more than 12 hours illumination. Such results were paralleled with the formation of CP-complex in thylakoid membrane. Considering the low ability of $CO_2$-fixation compared with that of other sun-plants, different photosynthetic intermediates at early period, and activities of both glycolate oxidase and catalase, ginseng is more likely to be $C_3$-plant.

우식(蟲齒)兒의 Saliva와 無蟲齒兒의 Saliva의 比較實驗

申富植,尹水子,李順熙 梨花女子大學校 藥學硏究所 1963 梨花藥學硏究 Vol.- No.4

치아의 본래 기능은 저작이다. 저작은 소화의 전계단이므로 치아의 결손은 소화에 까지 그 영향이 있을뿐만 아니라 특히 성장기에 있는 아동들이 영양상태에 까지 그 영향이 있다. 충치자면 물론 저작이 불량하고 불량하면 소화흡수에 큰영향이 있을것이고 이것은 곧 saliva에도 어떤 영향이 있을것이다. 현재까지 구체적으로 충치자의 saliva와 무충지자의 saliva에 대한 실험이 적으며 특히 생화학적 연구는 더욱 적다.

한국 비만 여성의 신체 계측에 의한 체지방 추정

심경원,김지연,서희선,이홍수,이상화,강지현 대한비만학회 2002 The Korean journal of obesity Vol.11 No.2

연구배경 : 국내 비만 여성을 대상으로 비용이 적게 들고 단순하면서도 보다 정확하게 체지방률을 추정할 수 있는 체지방률 추정식을 작성함으로써 쉽게 체지방률과 조절해야하는 지방의 양을 판단할 수 있도록 하고자 한다. 방법 : 이대목동병원 비만클리닉을 처음으로 내원한 19세 이상의 성인 여자 607명 중 체질량지수가 25 kg/㎡ 이상인 500명을 연구대상으로 하여 목, 가슴, 허리, 엉덩이, 대퇴, 하퇴, 발목, 상완, 전완, 손목의 10부위의 둘레와 생체전기저항분석법 (bioelectrical impedance analysis, BIA) 방식의 체성분 분석기를 이용하여 체지방률을 측정하였다. 체지방률 추정식을 구하기 위해 BIA에 의한 체지방률을 종속변수로 하고 , 신체 둘레 계측기 및 신장, 체중, 체질량지수, 연령을 독립변수로 하여 단계별 다중회귀분석 (multiple stepwise regression)을 시행하였다. 결과 : 신장과 체중, 연령, 체질량지수 및 신체 둘레 측정치 중 체지방률을 반영하는 지표는 체질량 지수, 전완둘레, 신장, 엉덩이 둘레, 하퇴둘레였고, 이 다섯가지 지표를 이용한 체지방률 추정식은 66.1%의 예측력과 2.86%의 측정 오차를 나타냈다 (R^2=0.661, SEE=2.86). 결론 : 비만한 성인 여성에서 신장과 체중, 연령 및 신체 둘레 계측치를 이용한 본 연구의 추정식은 체지방률(%)을 적은 오차범위로 비교적 정확하게 반영하였다. Background : This study was conducted to develop a regression equation that accurately estimates body fat percentage using relatively easy and inexpensive method in adult obese Korean women. Method : Data were collected among 500 obese Korean women visiting obesity clinic in Ewha woman's university Mokdong hospital, Seoul, Korea. Height, weight, and circumferences at ten body sites (neck, chest, waist, hip, thigh, calf, ankle, arm, forearm, wrist) were measured s well as total body bioelectrical impedance. Results : The full regression equation estimates body fat percentage included six variables : BMI, forearm circumference, height, hip circumference, thigh circumference. This equation accounted for 66.1% of the variance in body weight measured by bioelectrical impedance, and their standard error of estimate was 2.86%. Conclusion : For the obese Korean women in this study, circumference measurements provided a s relatively good estimation of body fat percentage.