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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
소아의 하악 과두 골절의 비외과적 치료 : 증례보고 CASES REPORTS
이정근,박익수,노양호,김동우,김우형,이희철 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.1
Of all facial fractures in children, condylar fractures have the greatest propensity to produce a growth disturbance. The pediatric condylar fracture occurs very frequently in the mandible, but this injury is occasionally ignored due to difficulty of diagnosis and no cooperation of patient. The adequate initial diagnosis and active treatment must be performed because delayed and improper treatment lead to possible severe complications such as facial asymmetry, TMJ pain, limiation of motion and deflection, midline deviation of the dental arch. So, the goal of managing condyle fractures in the growing patient is to restore mandibular symmetry, occlusion, function without interfering with future growth. Commonly, fracture teatment aims at restoring function through repositioning and rigid fixation of the bony fragments. However, the generally preferred management of condylar fractures in growing children is nonsurgical. So, we present the clinical and radiographic follow-up results of 4 condylar fractures in pediatric patients whom we managed in conservative and functional method. We can summarize our protocol in management of pediatric condylar fracture as the following: The IMF using acrylic resin splint with circumferential wiring was performed for 1 or 2 weeks. After releasing IMF, the active physical therapy was done with guiding elastic band. Opening deviation was controlled by mannual pressure of surgeon or parents for 2 weeks. When unstable occlusion or functional problem remained, functional appliance after construction bite registration was used for several months.
박익수,이정근,노양호,김동우,김우형,이희철 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2
Olfactory neuroblastoma is an uncommon malignant tumor(just over 300 cases have been reported in the medical literature by 1996)arising within the nasal cavity. This tumor has a neuroectodermal cell origin and is believed to specifically arise from the olfactory epithelium. The tumor was ftrst decribed in the French medical literayure by Berger and associates in 1924 by the name esthesioneuropitheliome olfactif. The english version of this term is esthesioneuroblastoma, and current medical literture uses this name interchangeably with olfactory neuroblastoma. We experienced a case of olfactory neuroblastoma in the mxillary sinus. We treated this patient with tumor resection, chmotherapy and radiotherapy. And now, the patient has been following up for 2years 6month, but olfactory neuroblastoma is very rare. SO we report this case with a review of literature.
흰쥐에서 음경발기 평가의 척도로서 음경해면체내압측정술 확립
송윤섭,김용준,이광우,김준모,문기혁,박영호,민영기,유형균,김형건 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1
Purpose: Because studies about the control of penile erection at the entral nervous system was dependent on the animal experiments, establishment of measuring penile erection is important to evaluate the effects changes at the central nervous system on the penile erection. Intracavernous pressure measurement in rats has been introduced as a suitable index for the evaluation of penile erection but this method is invasive and technically difficult. So, we established the intracavernous pressure measurement in rats as the experimental index for penile erection. Materials and Methods: 42 male adult Sprague-Dawley rats (250-300gm) were divided to saline or papaverine treated group. Rats were placed on a heating table to maintain their body temparature and anesthetized with 50mg/kg of pentobarbital sodium by intraperitoneal injection. A cannula was inserted to the left carotid artery to measure systemic blood pressure. Saline (0.05, 0.1ml), papaverine(0.05, 0.1, 0.25, 0.5, 1.0, 2.0mg) were injected intracavernously via 26 guage needle filled with saline or papaverine which connected to pressure transducer and polygraph was inserted into the corpus cavernosum on one side to inject the drug and to measure intracavernous presure. Results: Properly executed insertion and intracavernous administration produced a instantaneous but transient rise in intracavernous pressure that substantially stabilized and maintained at 5.4±0.4mmHg. Intracavernous pressure and duration of penile blood flow following intracavernous injection of papaverine are increased comared to those of saline. Conclusions: Monitoring intracavernous pressure in rats represents a suitable index for the evaluation of penile erection in small laboratory animals.
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)
김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3
Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.
Hyong Woo Moon,Jung Woo Park,Kyu Won Lee,Hyun Cheol Jeong,Jin Bong Choi,Sae Woong Choi,Woong Jin Bae,Hyuk Jin Cho,U-Syn Ha,Sung Hoo Hong,Jeong Ho Geum,Seong Bin Hong,Sae Woong Kim 대한남성과학회 2017 The World Journal of Men's Health Vol.35 No.1
Purpose: This study investigated the effect of goji (Lycium chinense Mill.) on erectile dysfunction in old-aged rats. Materials and Methods: Twenty-four 18-month-old male Sprague-Dawley rats (defined as old-aged rats) were used. Treatment groups contained eight rats each: a control group, goji extract of 150 mg/kg/day group, and goji extract of 300 mg/kg/day group. Treatment was by orogastric tube once daily for 6 weeks. After 6 weeks of treatment, testes weight, serum testosterone, superoxide dismutase, nitric oxide (NO)-cyclic guanosine monophosphate (cGMP)-related parameters, intracavernous pressure/mean arterial pressure, and histological changes were examined. Results: Treatments with goji extracts increased serum testosterone level, increased the expression of endothelial NO synthase, neuronal NO synthase, and cGMP, improved the oxidative stress marker, and decreased corporal fibrosis. Conclusions: Our results indicate that goji extract may have a positive effect on erectile dysfunction via its antioxidant effects.
Lee, Jeong Eun,Lee, Seung Chul,Won, Young Ho,Lee, Jee Bum,Yoo, Hyoung Chul,Lee, Hyong Woo 대한피부과학회 2001 Annals of Dermatology Vol.13 No.1
Background : Nitric oxide synthase (NOS) is known to mediate ultraviolet B (UVB)-induced skin inflammation However, there is still ambiguity as to which NOS isotype mediates the process in vivo. Furthermore, contradictory results have been reported on which cell types respond to UVB irradiation in vitro. Objective : This study was performed to evaluate the change of inducible NOS (iNOS) expression in vivo as a result of UVB radiation on the skin of a rat. Method : To examine the time-course change in iNOS expression in the rat skin, the rats were exposed to 400 mJ/㎠ of UVB radiation, and skin samples were taken at various time intervals up to 48 h. iNOS expression on the skin of a rat was evaluated by both Western blot analysis and immunohistochemical staining. Results : From Western blot analysis, UVB irradiation induced inducible NOS (iNOS) expression in the epidermis at 12-48 h postirradiation with a peak expression at 24 h. Immunohistochemical staining revealed that UVB-induced iNOS expression was localized to the epidermis and infiltrating inflammatory cells in the upper dermis of the rat. Conclusion : iNOS was induced by UVB irradiation on the skin of a rat, mainly in the epidermis. Therefore, iNOS is supposed to be one of the major mediators with regard to inducing an inflammatory response in UVB-irradiated rat skin in vivo.
Asymptotic Analyses of a Statistical Multiplexor with Heterogeneous ATM Sources
Lee, Hyong-Woo,Mark, Jon-Wei The Korean Institute of Electrical Engineers 1997 Journal of Electrical Engineering and Information Vol.2 No.3
Two asymptotic analyses of the queue length distribution at a statistical multiplexor supporting heterogeneous exponential on-off sources are considered. The first analysis is performed by approximating the cell generation rates as a multi-dimensional Ornstein-Uhlenbeck process and then applying the Benes queueing formula. In the second analysis, w state with a system of linear equations derived from the exact expressions of the dominant eigenvalue of the matrix governing the queue length distribution. Assuming that there are a large number of sources, we obtain asymptotic approximations to the dominant eigenvalue. Based on the analyses, we define a traffic descriptor to include the mean and the variance of the cell generation rate and a burstiness measure. A simple expression for the quality of service (QoS) in cell loss rate is derived in terms of the traffic descriptor parameters and the multiplexor parameters (output link capacity and buffer size). The result is then used to quantify the factors determining the required capacity of a call taking the statistical multiplexing gain into consideration. As an application of the analyses, we can use the required capacity calculation for simple yet effective connection admission control(CAC) algorithms.