치과 기공사들에게서 나타나는 호흡기 증상과 이의 관련 요인

김웅철,오세윤,김지환,김진완,이준석,이가영,이세훈,유진호,김태석 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.1

This study was carried out to investigate subjective respiratory symptoms and their attributable factors in Korean dental laboratory technicians. A questionnaire was mailed to randomly selected 1,900 dental laboratory technicians. Among them, 1,344 dental technicians completed the questionnaires and returmned them. Validity and reliability tests on the questionnaires were carried out before the main survey. To investigate risk factors on respiratory subjective symptoms, we performed analysis on distribution of characteristics, and then investigated univariate analysis and multiple logistic regression analysis. The prevalence rate of wheezing, cough and phlegm, and dyspnea was 4.8%, 33.9%, 54.9%, respectively. Statistically significant factors inducing subjective respiratory symptoms by multiple logistic regression analysis were sex, smoking, exercise, health examination, work hours a day, investment gas, investment dust, metal fume, resin vapor, and asbestos dust. Considering the results above, it seems that most subjective respiratory symptoms are related with health habits and occupational environmental-related factors. The result, consideration in mind, suggest that health promotion programs for smoking cessation, regular health examination, and physical exercise in health habit, and improvement on casting and resin work in dental technological environment be necessary.

악안면 골격 형태에 따른 교합평면각의 변화에 관한 두부 방사선학적 연구

오세윤,김웅철,김지환,이준석,김진완,유진호,김태석 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保健科學論集 Vol.25 No.1

A correlation analysis was made to understand the interaction between the growth patterns of some craniofacial skeletal components and occlusal plane inclination. 5 angular measurements(S.a. Ar.a, Go.a, UGo.a, LGo.a), 6 linear measurements(ACBL, PCBL, RH. MBL. AFH. PFH) and OP/SN. obtained from 83 cephalometric tracing records, were selected and the relationship between the occlusal plane angle and those measurements were analyzed statistically. Ramus Height(r=-0.55), Posterior Facial Height(r=-0.41), were found to be negatively related with Occlusal Plane angle, while Lower Gonial angle(r= 0.35), Saddle angle(r= 0.24) were found to be positively related with Occlusal Plane angle(p(0.05). The results obtained from the above analysis were further assessed with stepwise regression analysis, using Occlusal Plane angle as a dependant variable, and RH, LGo.a and S.a as explanatory variables. Stepwise regression analysis revealed that all the explanatory variables were found to be significant.(p<0.05) [OP/SN] = -8.74-0.33(RH)+0.23(S.a)+0.20(LGo.a). (R²=0.44). This stepwise regression analysis explains, to some extent, the relationship between the growth patterns of some craniofacial skeletal components and the occlusal plane inclination. 1. The inclination of Occlusal Plane angle is noticeably related with the growth patterns of some craniofacial skeletal components, i.e. RH, PFH, Saddle angle and Lower Gonial angle 2. In high Occlusal Plane angle, the Ram us Height tends to be shorter, and the Saddle angle and Lower Gonial angle tend to be obtuse.

요로감염증 환자의 치료에서 메로페넴(Meropenem)과 이미페넴/실라스타틴(Imipenem/Cilastatin)의 임상효과 및 안정성

김세웅,이승주,이지열,조용현,신완식,윤문수 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

목적 :메로페넴은 실라스타틴을 복합투여하지 않아도 되는 새로운 계열의 카바페넴계 항생물질이다. 요로감염 치료에 있어서의 메로페넴의 효과와 안전성을 평가하기 위하여 기존의 카바페넴계 항생물질인 이미페넴/실라스타틴과 동시에 비교임상실험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법을 통하여 시행하였다. 1996년 10월부터 1998년 2월까지 가톨릭대학교 의과대학 부속 성모병원 및 울산대학교 외과대학 부속 중앙병원 비뇨기과에 입원한 신우신염과 복잡성방광염 환자 115명을 대상으로 하였고, 연속적 무작위 배정방법을 통하여 메로페spa군 58명과 이미페넴/실라스타틴군 57명으로 분류하였다. 두가지 약제는 모두 0.5 g을 12시간 간격으로 정맥주사 하였고, 평균 투약기간은 4일 (3-8일) 이었다. 임상효과, 세균학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 67명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 메로페넴군은 34명이었고, 이미페넴/실라스타틴군은 33명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 메로페넴투여군은 34례중 32례 (94.1%)에서, 이미페넴/실라스타틴투여군은 33례중 29례 (87.9%)에서 유효율을 보였다. 세균학적 평가에서 메로페넴 투여군은 34례중 32례 (94.1%)에서, 이미페spa/실라스타틴투여군은 33례중 29례 (87.9%)에서 세균학적 소실율을 보였다. 세균학적 재발 은 각각 4명과 7명이 나타났고, 재감염은 메로페넴군은 나타나지 않았지만, 이미페넴/실라스타틴군은 2명이 나타났다. 임상효과와 세균학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 부작용은 메로페spa투여군 56례중 1례 (1.8%)에서, 이미페넴/실라스타틴투여군 53례중 1례 (1.9%)에서 나타났으며, 임상검사치 이상은 메로페넴투여군 45례중 10례 (22.2%)에서, 이미페넴 실라스타틴투여군 44례중 8례 (18.2%)에서 나타났으나 전체적으로 특별히 문제가 된 증례는 없었다. 결론 :결론적으로 메로페spa은 신우신염 및 복잡성방광염과 같은 요로감염에 대하여 이미페넴/실라스타틴과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Metopenem is the first of a new class carbapenems which may be administered without cilastatin. The clinical study was carried out to assess efficacy and safety of metopenem in the treatment of urinary tract infections, in comparison to imipenem/cilastatin. Methods : This was a controlled, two-center, prospective, randomized study with two parallel groups. From October 1996 until February 1998, a total of 115 consecutive patients with urinary tract infections, such as pyeolonephritis and complicated cystitis, were randomly allocated into two groups, 58 in the meropenem group and 57 in the imipenem/cilastatin group. Both drugs were administered intravenously, at a dose of 0.5 g every 12 hours. The mean duration of therapy was 4 days (3-8 days) for both treatment. Clinical and bacteriological reponses were assessed at the begining of treatment, during treatment, at the end of treatment, and follow-up (1-2 weeks). Results : A total of 67 patients, 34 of meropenem and 33 of imipenem/cilastatin, were evaluable for response. Overall, a positive clinical response (recovery and improvement) was observed in 32 (94.1%) of 34 patients treated with meropenem and in 29 (87.9%) of 33 patients with imipenem/cilastin and the corresponding eradication rates of the primary pathogens were 32 (94.1%) of 34 patients and 29 (87.9%) of 33 patients, respectively. The microbiological relapse after the treatment completion was recorded in 4 patients treated with meropenem and 7 patients given imipenem/cilastath and superinfections occurred in none and 2 patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. Both drugs were well tolerated with adverse events considered to be related to therapy being recorded for 1 (1.8%) of 56 patients treated with meropenem and 1 (1.9%) of 53 of those who had been given imipenenjcilastatin. Conclusion : Empirial monotherapy with meropenem was therefore as effective and as well tolerated as that with imipenem/cilastatin for the treatment of urinary tract infections.

급성 단순하부요로감염증 치료에서 노르플록사신과 루플록사신의 임상효과 및 안전성

김세웅,이지열,이승주,조용현,윤문수 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.1

목적 : 루플록사신은 긴 반감기와 넓은 항균력을 가진 퀴놀론계 항생물질이다. 급성 단순하부요로감염 치료에 있어서의 루플록사신의 효과와 안전성을 평가하기 위하여 기존의 퀴놀론계 항생물질인 노르플록사신과 비교임상시험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법으로 진행하였으며 1997년 8월부터 1999년 3월까지 가톨릭대학교 의과대학 부속 성모병원 비뇨기과에 내원한 급성 단순하부요로감염 환자 72명을 대상으로 하였다. 연속적 무작위 배정방법을 통하여 루플록사신군 36명과 노르플록사신군 36명이 루플록사신 400㎎을 단회 경구투여 받거나 노르플록사신 400㎎을 12시간 간격으로 3일간 6회 경구투여 받았다. 임상효과, 미생물학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 64명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 루플록사신군은 32명이었고, 노르플록사신군은 32명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 루플록사신투여군은 32례중 32예(100%)에서, 노르플록사신투여군은 32례 중 31례(96.9%)에서 만족할 만한 결과를 얻었다. 미생물학적 평가에서 루플록사신투여군은 32례 중 29례(90.6%)에서, 노르플록사신투여군은 32례 중 28례(87.5%)에서 미생물학적 소실을 보였다. 미생물학적 재발은 루플록사신군과 노르플록사신군에서 각각 1례(3.1%)과 2례(6.3%)가 나타났고, 재감염은 각각 2례(6.3%)와 1례(3.1%)가 나타났다. 임상효과와 미생물학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 약물역동학적 검사상 루플록사신은 노르플록사신에 비해 높은 MIC를 갖고 있지만 긴 반감기를 통해 소변내에서 높은 농도와 요 살균력을 유지함을 알 수 있었다. 부작용은 루플록사신투여군 34례 중 5례(14/7%)에서, 노르플록사신투여군 35례 중 1례(2.9%)에서 나타났으며, 대부분의 소화기계통의 이상반응 이었으며, 모두 경증으로 24시간 이내에 소실되었다. 루플록사신투여군 중 2례에서는 경증의 중추신경계의 이상반응이 관찰되었다. 결론 : 결론적으로 루플록사신은 급성 단순하부요로감염에 대하여 1회 투여만으로도 노르플록사신의 3일 투여법과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Rufloxacin is a broad-spectrum quinolone that exhibits a prolonged elimination half-life. The purpose of this study is to evaluate the efficacy and safety of a single dose of rufloxacin, campared with those of a norfloxacin standard treatment. Methods : This was a open. randomized. parallel-group, phase 11 clinical trial. A total of 72 women with acute lower urinary tract infections were included and randomly assigned to one of the treatment regimens: rufloxacin 400㎎ single dose, or norfloxacin 400㎎ b.i.d. for 3 days. Clinical and bacteriological assessments were performed twice at the third day and the seventh or tenth day after inclusion. Results : A total of 64 patients(32 and 32 patients in the rufloxacin and norfloxacin groups, respectively) were considered clinically and bacteriologically evaluable. Overall, a clinical response(recovery and improvement) was observed in 32 (100%) of 32 patients treated with rufloxacin and in 31 (96.95) of 32 patients with norfloxacin. The corresponding eradication rates of the primary pathogens were 90.6%(29/32) and 87.5%(28/32), respectively. The microbiological relapses between the seventh and tenth day were recorded in 1 patient(3.1%) and 2 patients(6.3%) in the rufloxacin and norfloxacin groups, respectively. The superinfections occurred in 2(6.3%) and 1(3.1%) patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. The pharmacodynamic evaluation showed similar median urine bactericidal titers(UBT) for both treatment groups against initial isolates, despite a higher MIC of rufloxacin than that of norfloxacin. Five patients (14.7%) in the rufloxacin group and 2 patients (5.7%) in the norfloxacin group reported 9 and 4 adverse events, respectively, almost all of them being mild and lasting <24 h. Overall, gastrointestinal reactions were the most frequent adverse events reported. However, 2 patients treated with rufloxacin reported 3 central nervous system adverse events. Conclusion : This study suggests that single dose of rufloxacin treatment is effective and well tolerated as norfloxacin 3-day standard treatment in acute uncomplicated lower urinary tract infections.

치과기공사의 스트레스 증상과 직무요인과의 관련성 연구

김지환,오세윤,김웅철,유진호,김태석,이준석,이원철 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.2

This study was carried out to investigate psychiatric stress symptoms and stress- inducing factors, such as role overload, work demand, work procedure and so forth in korean dental laboratory technicians. Questionnaires were mailed to randomly selected 1000 dental technicians who were systematically selected. Among them, 786 dental technicians completed the questionnaires and returned them. Validity test and reliability test on the questionnaires were done prior to the main survey, using the SCL-90-R as a standard. Stress-inducing factors were identified with a multiple regression analysis on the continuous variables. To investigate stress-inducing factors on stress symptoms, analysis on distribution of characteristics was performed, and then correlation analysis and multiple regression analysis was carried out. The results of the study were as follows: According to multiple regression analysis, there was a statistical correlation between stress symptoms and role overload, work procedure, occupation conflict, interpersonal relationship, social support, personality traits in stress symptom(GSID). The stress symptoms in korean dental laboratory technicians seemed to be mostly job related ones, and considering the results obtained from the study, it is suggested that reducing work load and proper health promotion programs for dental technicians be necessary.

치과기공사 국가시험 과목 타당성 연구

김웅철,이원철,손영석,오세윤,김부섭,유진호,김지환 한국보건의료인국가시험원 2005 보건의료교육평가 Vol.2 No.1

This study prepared a basic framework for the development and improvement of Korean Dental Technicians' Licensing Examination, based on actual test questions. A peer review was conducted to ensure relevance to current practices in dental technology. For the statistical analysis, 1000 dental laboratory technicians were selected; specialists in dental laboratory technology (laboratory owners, educators, etc.) were involved in creating valid and reliable questions. Results indicated that examination subjects should be divided into three categories: basic dental laboratory theory, dental laboratory specialties, and a practical examination. To ensure relevance to current practice, there should be less emphasis on basic dental laboratory theory, including health-related laws, and more emphasis on dental laboratory specialties. Introduction to dental anatomy should be separated from oral anatomy and tooth morphology; and fixed prosthodontics should be separated from crown and bridge technology and dental ceramics technology. Removable orthodontic appliance technology should be renamed 'orthodontic laboratory technology'. There should be less questions related to health related law, oral anatomy, dental hygiene, dental materials science and inlay, while the distribution ratio of questions related to tooth morphology should be maintained. There should be a decrease in the distribution ratio of questions related to crown and bridge technology, dental ceramics technology, complete dentures and removable partial dentures technology, and orthodontic laboratory technology. In the practical examination, the current multiple choice test should be replaced with tooth carving using wax or plaster. In dental laboratory specialties, subjects related to contemporary dental laboratory technology should be included in the test items.

우리나라 치과 기공사의 건강 습관에 영향을 미치는 요인

오세윤,김웅철,김지환 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保健科學論集 Vol.25 No.1

This investigation was carried out to evaluate the relations between the levels of health practices and their attributable factors in Korean dental laboratory technicians A questionnaire listing six groups of health practices and their related factors was mailed to randomly selected 1,900 dental laboratory technicians. Among them, 1,344 dental laboratory technicians filled out the questionnaires and returned them. Before the start of main survey, a pilot survey was carried out for validity test of the questionnaire. All the data obtained were corded and analyzed with PC/SAS 6.12 program. The level of inappropriate health practices was the highest in irregular exercise(85.3%), and followed by smoking(61.0%), drinking of alcohol(59.1%), irregular eating habits(45.6%), inappropriate sleep duration(32.2%), and obesity(9.4%). Statistically significant factors by multiple logistic regression analyses were sex. work part in obesity: age. work area. number of employees in hours of sleeping: sex, self assessed health status, health examination, work area, work hours in eating habits: sex, marital status, education in smoking : sex in drinking of alcohol : self assessed health status : health examination, work hours in exercise '. and sex, work hours in health practice index. With the above considerations in mind, the levels of health practices in Korean dental laboratory technicians was relatively low and that was attributable to most of the sociodemographic characteristics, health examination and health status and work history. It is suggested that health promotion programs for promoting self-assessed health status, carrying out health examination, reducing work hours, and measures for elevating the level of health practice of male techinicians be necessary.

3% NaCl 水溶液中에서 複合組織鋼의 第2相 硬度 및 反復速度 變化가 腐蝕疲勞擧動에 미치는 影響

吳世旭,金雄執 東亞大學校 海洋資源硏究所 1992 硏究論文集 Vol.5 No.2

Only the 2nd phase hardness of martensite in dual phase steel which was composed of the martensite and ferrite was changed by heat treatment. The corrosion fatigeue fracture behaviors were conducted by cantilever by cantilever type of self-made roated bending fatigue testing machine at cyclic frequencies of 25Hz and 0.5Hz in 3% NaCl solution. The fatigue strength was increased as the hardness of the 2nd phase and cyclic frequency got higher. In case of 302 MPa and 25Hz , corrosion fatigue fracture behavior was effected by mechanics but in case of 137MPa and 0.5Hz. by electric-chemistry, Also it wsas effected by mechanics and corrosive dissolution of crack edge in cse more than crack length lmm at 137MPa, 0.5Hz. As cyclic frequency and stress level got lower , the relation of AK and da/dN decreased influence for changer of the 2nd phase hardness, A s stress level gor lower and hardness of the 2nd phase gor higher, the roughness of fracture surface was increased.

비뇨기과 입원환자에서 진통이 미치는 Nabumetone(Unimetone^(�))의 임상적 효과

이홍우,김세웅,이광돈,조용현,윤문수 최신의학사 1994 最新醫學 Vol.37 No.6

Efficacy of a vaporization-resection of the prostate median lobe enlargement and vaporization of the prostate lateral lobe for benign prostatic hyperplasia using a 120-W GreenLight high-performance system laser: the effect on storage symptoms.

Kim, Kang Sup,Choi, Sae Woong,Bae, Woong Jin,Kim, Su Jin,Cho, Hyuk Jin,Hong, Sung-Hoo,Lee, Ji Youl,Hwang, Tae-Kon,Kim, Sae Woong Baillière Tindall ; Springer London 2015 LASERS IN MEDICAL SCIENCE Vol.30 No.4

<P>GreenLight laser photoselective vaporization of the prostate (PVP) was established as a minimally invasive procedure to treat patients with benign prostatic hyperplasia (BPH). However, it may be difficult to achieve adequate tissue removal from a large prostate, particularly those with an enlarged median lobe. The purpose of this study was to investigate the feasibility and clinical effect of a 120-W GreenLight high-performance system laser vaporization-resection for an enlarged prostate median lobe compared with those of only vaporization. A total of 126 patients from January 2010 to January 2014 had an enlarged prostate median lobe and were included in this study. Ninety-six patients underwent vaporization only (VP group), and 30 patients underwent vaporization-resection for an enlarged median lobe (VR group). The clinical outcomes were International Prostate Symptoms Score (IPSS), quality of life (QOL), maximum flow rate (Q max), and post-void residual urine volume (PVR) assessed at 1, 3, 6, and 12 months postoperatively between the two groups. The parameters were not significantly different preoperatively between the two groups, except for PVR. Operative time and laser time were shorter in the VR group than those in the VP group. (74.1 vs. 61.9 min and 46.7 vs. 37.8 min; P?=?0.020 and 0.013, respectively) and used less energy (218.2 vs. 171.8 kJ, P?=?0.025). Improved IPSS values, increased Q max, and a reduced PVR were seen in the two groups. In particular, improved storage IPSS values were higher at 1 and 3 months in the VR group than those in the VP group (P?=?0.030 and 0.022, respectively). No significant complications were detected in either group. Median lobe tissue vaporization-resection was complete, and good voiding results were achieved. Although changes in urinary symptoms were similar between patients who received the two techniques, shorter operating time and lower energy were superior with the vaporization-resection technique. In addition, vaporization-resection may have a beneficial effect on storage symptoms.</P>