엔로플록사신 액제의 닭유래 병원세균에 대한 시험관내 항균효과 시험

윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

In this study the antimicrobial spectrum and sensitivity of a liquid formulation of enrofloxacin against the major six pathogenic bacteria isolated from the diseased poultry in Korea were evaluated in comparison with ciprfloxacin (CFX), gentamicin (GM) and penicillin (PC). A liquid form of enrofloxacin, a test material and ciprofloxacin showed at least 83% antibacterial activity against all of six test pathogenic microorganisms at the fixed concentration of 10 ㎍/㎖. Gentamicin and penicillin revealed much lower antibacterial activity at the same condition. We evaluated the liquid form of enrofloxacin as having widespread antibacterial spectrum against poultry infections. The liquid form of enrofloxacin showed potent antibacterial activity, with the MIC range being 0.12∼2 ㎍/㎖ against Gram positives, 0.06∼2 ㎍/㎖ against Gram negatives and 0.5∼2 ㎍/㎖ against Mycoplasma spp. These values were equivalent to or somewhat higher than those of ciprofloxacin, but much lower than those of gentamicn and penicillin. This new liquid form of enrofloxacin would find its way in application of mixing with drinking water for the prevention and treatment of diverse infections in chickens.

엔로플록사신 액제의 닭 호흡기 및 소화기 감염증에 대한 예방 및 치료효과

윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

We evaluated the efficacy of the liquid form of enrofloxacin against poultry respiratory and digestive infections, the major problems in the poultry industry, from diverse diagnosis viewpoints. Results obtained through this study were as follows: 1. The liquid form of enrofloxacin showed good acceptability to poultry owing to no abhorrence to the drug by chickens, which indicated its suitability for mixing in drinking water. 2. The application of the enrofloxacin formulation improved the productivity of the chicken farm to a great extent by lowering the death toll of chicken raised in the farm. 3. The use of the drug shortened the days to the market, and increased the body weight at the time of marketing. 4. Preventive and therapeutic effects of the liquid enrofloxacin were observed higher than ampicillin, a major antibiotic used in poultry farming. From above results, the liquid form of enrofloxacin would find its use for the prevention and treatment of digestive and respiratory infections, let alone the growth promotion and feed efficiency, especially in the chicken farming practice.

水原樹木園地域內의 自然森林植生 調査結果

李峻雨,禹保命,辛俊煥,金景河,兪鐘德 서울大學校 農科大學 1985 서울대농학연구지 Vol.10 No.2

樹木園 活成豫定地를 對象으로 土壤 水分含量과 植生을 調査하여 앞으로의 樹木園 造成에 필요한 情報를 얻음과 동시에 樹木園 造成에 따른 植生破壞後 原來植生에 關한 情報가 必要할 때 參考하기 爲하여 1985年 6月 12日에 本 調査를 實施하였는데 그 結果는 다음과 같다. 1. 全體的으로 겨이삭(Agrostis clavata var. nukabo)의 優占度가 매우 높았으며 씀바귀(Ixeris dentata)와 흰씀박귀(Ixeris dentata var. albiflora)는 극히 乾燥한 곳을 제외하고는 대부분 優占度가 높았다. 濕한 곳에는 왕비늘사초(Carex maximowiczii), 기장대풀(Isachne globosa) 等이, 극히 乾燥한 곳에서는 잔디(Zoysia japonica)가, 보통 乾燥한 곳에서는 그늘사초(Carex lanceolata), 김의털(Festuca ovina) 等이 優占度가 높았다. 2. 特히 稀貴植物인 선제비꽃(Viola raddeana)群落과 진퍼리용담(Grntiana scabra var. buergeri for stenophylla)이 Block 3(습지)에 있으므로 앞으로 이 區域은 注意깊게 保存되어야 할 것이다. 3. 土壤 水分含量이 最低 14.7%에서 最高 89.9%까지 分布하여 乾濕의 差異가 심하게 나타났다. 特히 調査 時期가 乾濕期인데도 土壤 水分含量이 70%가 넘는 곳이 3개소나 된다. 이 곳은 地下水位가 높아서 濕地이므로 濕地植物園을 造成해야 될 것이다. 植生의 造成狀態가 區域에 따라 變異가 심하게 나타났기 때문에 이 林地가 매우 不安定한 狀態에 있다고 볼 수 있을 것이다. Soil moisture contents and vegetation of the forest land planed to establish the Suweon Arboretum had been investigated to obtain some informations for establishing arboretum, and also for keeping the original vegetation composition data after the arboretum was established. The results obtained in this investigation could be summarized as follows. 1. In general, the coverage of Agrostis clavata var. nukabo was very high. The coverage of lxeris dentata and ixeris dentata var. albiflora were high except for very arid blocks. Coverages of Carex maximowiczii and Isachne globosa were high in wet blocks. The coverage of Zoysia japonica was high in very arid blocks and that of Carex lanceolata and Festuca ovina in arid blocks were high. 2. Soil moisture content was distributed from 14.7% to 88.9%. Especially the fact of the high moisture content (74.7, 77.5, 88.9%) in dry season implied that the ground water level of this area was high. The vegetation composition of this forest was varied, too. Therefore, it is considered that the stability of this forest was fragile.

지면판위 복수 장애물 주위 유동장의 가시화(Ⅰ)

이동환,송창수,강경욱 울산대학교 1991 공학연구논문집 Vol.22 No.2

地面板위에 모양이 서로 다른 복수 장애물을 바람의 방향과 수직으로 배열(Side-Side)하여 액체4염화 티타늄을 관찰대상 표면에 직접 도색하여 유동장을 효과적으로 가시화 하였다. 장애물 사이의 간격이 좁아지면 틈을 통과하는 흐름은 어느 한쪽으로 傾斜진다는 특징이(Biased Flow) 확인되었고, 지면판위 박리선, Necklace Vortex, 후류등 3차원 유동장 특징이 확인되었다. Flow patterns around two-bluff bodies in side-by-side arrangements on the ground plane are easily visualized using liquid titanium tetrachloride. In two-dimensional flow field, the gap flow between two-bodies became biased to one side for closer spacing. Three-dimensional flow patterns, which have seperated regions, necklace vortices and other dynamic seperations, are dependant on the bluff-body shape and the gap-space ratio.

백서의 우울모형에서의 칼슘통로 길항제 에타베린(Ethaverine)의 항우울효과

이상경,김선희,김록우,윤성환,김용관,김경태,김영훈 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

연구목적: 본 전임상연구에서는 우울증의 두가지 동물모형을 통해 에타베린이 단독 혹은 이미프라민과 병용처치 되었을 때의 효과를 알아보고자 하였다. 방법: 표준화된 검사법인 강제수영검사를 사용하여 옹성백서에게 에타베린(20mg/kg) 및 이미프라민 (20mg/kg)을 단독 혹은 병용 처치하였을 때의 부동시간의 변화를 관찰하였고, 경도의 만성 스트레스를 3주간 가한 후 4주간 에타베린과 이미프라민을 단독 혹은 병용 처치하였을때의 자당섭취량의 변화를 관찰하였다. 결과: 약물을 1회 단기처치 및 7일간 장기처치한 강제수영검사에서 이미프라민 및 에타베린 단독처치는 대조군에 비하여 부동시간의 단축을 보였고 에타베린은 이미프라민의 부동시간 감소에 대한 증강작용을보였다. 경도의 만성스트레스 실험에서도 3주간의 스트레스로 인하여 감소된 백서의 자당섭취량을 이미 프라민 및 에타베린이 회복시켰으며, 치료초기에 두 약물의 병용처치효과가 두드러졌다. 결론: 본 연구의 결과는 에타베린이 향우울 효과를 가지고 있음을 시사하며, 삼환계 항우울제인 이미프라민의 항우울효과를 증강시키므로 에타베린의 임상적 활용 가능성을 보여준다. Objectives: This pre-clinical study was performed to assess the effects of ethaverine in the two kinds of behavioral models of depression in rats. Methods: We observed the changes of the immobility time in the froced swimming test and the quantity of sucrose consumed in the chronic mild stress model, using ethaverine(20mg/kg) alone, imipramine(20mg/kg) alone, or ethaverine and imipramine concomitantly. Results: In the forced swimming test, both single treatment and chronic treatment(for 7days) with imipramine or ethaverine significantly reduced the immobility time, and concomitant chronic treatment with ethaverine potentiated the effect of imipramine. In the chronic mild stress model, both imipramine and ethaverine reversed the decreased sucrose consumption induced by 3-week stress and concomitantly treated ethaverine potentiated the effect of imi-pramine in the early phase of treatment. Conclusions: The data suggest that ethaverine can be used alone or concomitantly with other antidepressants in the clinical situation.

金井山 林道開設에 따르는 問題点에 관한 硏究

이경재,류창희,김승환,박승범 東亞大學校生命資源科學大學附設 農業資源硏究所 1993 農業生命資援硏究 Vol.2 No.1

Mt. Gum-Jung is a very important mountain of Pusan which is connected to the large branch of Mt. Baek-Du, range including Mt. Baek-Du, Mt. Un-Ju, Mt. Ka-Zi, Chui-Seo and Mt. Gum-Jung. It is also attached to Nak-Dong river linked to Mt. Baek-Yang and Mt. Seung-Hak. Regarding the Korean peninsula as one natural ecosystem, the large branch of Mt. Gum-Jung. Therefore, it is very important to primarily preserve it from ecological point of view. In case of constructing the forest road, the width of the road is 4 meters approximately, but the actual damaged width of the forest which includes the shoulder of both sides of the road, drainage ditches and the areas cutting the lower plants of trees, will be around 20∼28 meters. Since the forest road paved with concrete pavements and the gravel divides the ecosystem of the forests and thus destroys the ecological system, it should be paved with the natural materials, such as soils, herbals and so forth. The forests of Mt. Gum-Jung which have almost been in the 2nd transitional stage, have some areas showing active ecosystem restoration, such as Carpinus spp., so they should be preserved very thoroughly. The marshy ecosystem of about 27,720㎡ which is at the height of 600meters above sea level, west to North Gate of Mt. Gum-Jung Castle, has the high watertable formed naturally. The existence of the marshy at the near of the mountain top is a remarkably rare phenomenon, the preservation of as the marshy ecosystem is absolutely necessary. At present, this area is completely destroyed by the thoughtless use. Furthermore, the construction of the drainage due to the forest roads may cause the change of the waterable height of the marshy ecosystem. The construction of the forest road near to the to of the mountain, having th egood landscape and the historic relics, results in many problems with the landscape. Putting together, the construction of the forest roads should consider the totality of Mt. Gum-Jung instead of only considering forest preservation. Also the scientific method of a sustainable use should be sought, which fully incorporates the problems such as the width and size of the forest roads, the pavement methods and materials, and the choice of sites without ecological and landscape problems.

알코올이 Dynamic Posturography에 미치는 영향

이진춘,고의경,장민호,이병주,백무진,노환중,왕수건,전경명 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.2

樹木園 造成地域內 地존作業을 위한 아까시나무 除去試驗

金景河,辛俊煥,李峻雨,兪鐘德,禹保命 서울大學校 農科大學 1985 서울대농학연구지 Vol.10 No.2

This experiment was conducted at the Seoul National University Arboretum at Seodun-dong, Suweon, Kyeonggi-do, Korea (1) to find out methods killing Robinia pseudoacacia L. effectively and (2) to minimize ecological and aesthetic problems. Glycine and 2, 4-D were treated in several concentration following the saw-scratching and cutting of stems on July 22 and 29, 1985. The results were measured on October 17, 1885. The results obtained were as follows: 1. Ecological problems were decreased by these methods. 2. In case of herbicides treatment on section area, aesthetic problems were minimized, and amounts of herbicide consumption were five times as little as in case of spraying plants with herbicides. 3. The death rate amounted to 100% when the ratio of Glycine solution to water was 1:3, so that the concentration, 1:3 was most economical to kill the tree throughly. 4. The death rate amounted to 100% when the ratio of Glycine solution mixed with 2, 4-D to water was 1:4, therefore Glycine solution mixed with 2, 4-D was more effective than pure Glycine solution. Since 2, 4-D solution was less expensive than Glycine solution and only small amounts of 2, 4-D solution was added, it was most economical and effective method that Glycine solution mixed with 2, 4-D was diluted to the concentration, 1:4 and treated on the stem.

기관골 신생증 1예

오영상,이은우,정종혁,문승원,김수현,김동한,양혁승,박정환,박경옥,강성수,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Tracheobronchopathia osteoplastica is a rare disorder of unknown cause characterized by the projection of numerous bony or cartilaginous submucosal nodules into the tracheobronchial lumen with sparing of the posterior membranous portion of tracheobronchial tree. In the past, most of the cases were diagnosed as secondary finding at autopsy. Nowaday, the key component of the evaluation is flexible fiberoptic laryngoscopy and bronchoscopy, which typically demonstrates irregular spicules of subrnucosal bone and cartilage projecting into the tracheobronchial lumen and causing various degrees of airway obstruction. A 45 years old man was visited Sunchon St. Carollo hospital due to discomfort on throat. We saw several nodules just below vocal cord via laryngoscope. The computed tomography revealed multiple small calcified nqdules on trachea and both main bronchi. Pathologic finding of bronchoscopic biopsy showed abnormal proliferation of bony and cartilagious nodules in the tracheal submucosa. These fingdings were consistent with tracheobronchopathia osteoplastica. We report here on a case of tracheobronchopathia osteoplastica with review of literature.

Rifampicin에 의한 것으로 추정되는 위막성 대장염1예

김수현,이은우,정종혁,문승현,김동한,양혁승,오영상,김호동,김도현,박혁,박정환,박경옥,이영직 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Pseudomembranous colitis, caused by altering the normal colonic flora and allowing the multiplication of Clostridium difficile, is an deleterious adverse effect of antibiotics. But it is rarely reported by rifampicin. Rifampicin is one of the first line drug in the treatment of tuberculosis and many patients are exposed to its potential adverse effects. We experienced a patient that had abdominal discomfort and hematochezia due to pseudomembranous colitis after receiving antituberculous medication, and which was probably caused by rifampicin. A 82 years old man was admitted with abdominal discomfort and hematochezia for one week. On the past history he had been diagnosed as endobronchial tuberculosis about 4 months ago. Colonoscopy revealed multiple discrete whitish mucosal lesion on rectosigmoid colon, and histologic findings were consistent with pseudomembranous colitis. The antituberculous agents were discontinued and vancomycin was administered. The patient's symptoms were resolved within several days. There was no recurrence after reinstitution of the antituberculous agents excluding rifampicin. We report here on a case of pseudomembranous colitis probably due to rifampicin.