사상의학과 형상의학의 유형분류의 연관성에 관한 연구

장아름,전수형,박세정,이현미,김규곤,이용태,지규용,이인선,김종원,Jang, A-Reum,Jeon, Soo-Hyung,Park, Se-Jung,Lee, Hyun-Mi,Kim, Kyu-Kon,Lee, Yong-Tae,Ji, Gyu-Yong,Lee, In-Sun,Kim, Jong-Won 사상체질의학회 2010 사상체질의학회지 Vol.22 No.3

1. Objectives: This study was performed to research the relationship between Sasang Constitutional medicine and Hyungsang medicine. 2. Methods: Four hundred and thirty applicants are involved in this study. They are devided into Sasang Constitution and Hyungsang Classification 3. Results and Conclusions: There are significances between Sasang Constitutional diagnosis and Hyungsang Classification. There are significantly more Bangkwang-body, Gi-kwa, Taeyang-hyung, Yangmyung-hyung in Taeyangin and Bangkwang-body, Jung-kwa, Soyang-hyung, Yangmyung-hyung in Soyangin. There are significantly more Dam-body, Gi-kwa, Taeyang-hyung, Yangmyung-hyung in Taeeumin and Bangkwang-body, Gi-kwa, Taeyang-hyung, Yangmyung-hyung in Soeumin.

혈중 및 호기 일산화탄소를 이용한 일산화탄소 헤모글로빈 농도간의 관련성 연구

김형수,박태혁,손지언,정갑열,김정만,김준연 동아대학교 2001 大學院論文集 Vol.26 No.-

This study was conducted to find a correlation between blood COHb and calculated COHb with expiratory air and related variables such as occupational and smoking factors. Author selected 69 healthy workers in 8 workplaces suspected CO exposure. Basic informations were collected by self-reported questionnaire and medical history taking. Author measured Indirect COHb concentration with expiratory air using Micro II-Smokerlyzer and blood COHb concentration using Oxymeter. The results of the study were summarized as follows : 1. In the smoker, mean blood COHb and calculated COHb with expiratory air were 2.21±0.98% and 2.27±0.97 %, and there was not a statistically significant difference. In the non-smoker, mean blood COHb and calculated COHb with expiratory air were 0.42±0.43 % and 0,65±0.30 %, and there was also not a statistically significant difference. 2. There were positive correlations between blood COHb and calculated COHb with expiratory air in both the smoker (r=0.91, p=0.0001) and non-smoker (r=0.73, p=0.0001). 3. In the smoker, the factors affected COHb were total smoking index (Pack × years) and passed time after the last smoking. 4. In the nonsmoker, the parking and driving groups had higher COHb concentration than others (p<0.05). In conclusion, there was no significant difference between indirect COHb concentration with expiratory air using Smokerlyzer and blood COHb concentration and there was a highly significant correlation between indirect and blood COHb concentrations. Therefore indirect COHb concentration with expiratory air is a useful screening method for CO exposure. Author suggest the resection of smoking during at least 90 minutes before measuring COHb concentration in order to exclude smoking effects.

폐결핵 환자 혈청에서 수용성 Interleukin 2 수용체 및 Adenosine Deaminase 활성도에 관한 연구

고정희,박성규,백상현,박찬권,박병수,안진영,최우석,박정규 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

Interleukin-2 (IL-2) induces T cell proliferation in an autocrine manner and provides a means by which antigen triggered T cells can be clonally expanded in vitro. During the following activation, the activity of IL-2 is mediated by specific high affinity IL-2 binding membrane receptors which are expressed shortly after activation. In this process, a 42 KD-fragment (soluble IL-2R) is continuously cleaved off and circulates as a soluble marker of T lymphocyte activation. Elevated level of soluble IL-2R has been identified in the serum of patients with malignant autoimmune and allergic disorders, systemic parasitic infection, undergoing graft versus host disease, acute or chronic lymphocytic leukemia and HIV-infection. ADA (adenosine deaminase) completes the process of differentiation of T cell and is essential for progression of T cell maturation. Therefore level of ADA is to correlated with magnitude of T cell immune response. The fact that expression of sIL-2R and ADA activity increases in peripheral blood T-lymphocytes of patients with active pulmonary tuberculosis suggests that T cell activation might have a major role in the pathogenesis of pulmonary tuberculosis. In order to evaluate the T cell immune response in pulmonary tuberculosis, we measured the serum concentration of sIL-2R and ADA activity in 17 patients with current pulmonary tuberculosis, 10 chronic inactive pulmonary tuberculosis, 10 as normal controls. (1) Current pulmonary tuberculosis had significantly higher levels of sIL-2R (237.24±95.47)when compared with those of inactive tuberculosis (78.6±11.06). and the control (68.17±15.4) group. (2) ADA activity in current pulmonary tuberculosis was significantly increased (34.41±20.63) when compared with those of inactive tuberculosis (24.7±14.36) and control (17.65± 5.94) group. (3) There was good correlation between sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group. (4) sIL-2R concentration and ADA activity was decreased significantly 6 months after anti-tuberculosis drug medication. In conclusion, sIL-2R concentration and ADA activity in serum in current pulmonary tuberculosis group was increased when compared with those of inactive pulmonary tuberculosis and the control group. By the way, T cell mediated immune response was enhanced in current pulmonary tuberculosis, but in inactive chronic pulmonary tuberculosis who had treated by antituberculosis drug medication, the concentration of sIL-2R and ADA activity was nearly normal.

40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

근적외선을 이용한 두개강내 혈종의 진단

박정율,홍기선,김상대,김세훈,임동준,조태형 대한체열학회 2003 대한체열진단학회지 Vol.3 No.1

천연 생약복합추출물이 Streptozotocin 유발 당뇨성 흰쥐의 장기무게 및 혈당내성에 미치는 효과

박형래,조정순 명지대학교 자연과학연구소 2006 자연과학논문집 Vol.25 No.-

상엽, 지황, 산약, 구기자 및 황기 등 5가지 천연복합추출의 일반성분 분석의 결과 100g 당 325 kcal이었으며, 수분함량 7.4%, 조지발 0.3g, 탄수화물 66.1g, 회분 11.7g이었다. 무기질 중 칼슘은 1503.96 mg, 칼륨은 2510.27 mg, 철분 9.68 mg, 소디움 1.20 mg이었다. streptozotocin(STZ)으로 당뇨를 유발시킨 흰쥐에 5가지 천연복합추출물(BG515)를 12주간 경구 투여한 후 다음과 같은 결과를 얻었다. 체중변화에서 실험군 모두에서 정상군에 비하여 유의적으로 낮은 체중증가를 나타냈었으며 BG515-4군에서 가장 낮은 체중증가 경향을 나타내었다. 평균 1일 식이섭취량 비교에서 STZ-control군을 포함한 실험군 모두에서 정상군에 비하여 현저한 증가를 나타내었으며 STZ-control군 및 천연복합물질 BG-515 투여군 사이에는 유의적인 차이는 없었다. 평균 1일 음수량 비교에서 당뇨가 유발된 STZ-control군을 포함한 실험군 모두에서 정상군에 비하여 6배 정도의 높은 음수량을 나타내었다. 신장과 간, 폐 및 심장조직의 중량은 STZ-control군을 포함한 실험군 모두에서 실험 전 기간에 걸쳐 정상군에 비해 상대적 중량이 유의적으로 높게 나타났으며 췌장의 중량도 정상군에 비해 실험군 모두에서 유의적인 증가를 나타내었으며, 비장의 중량은 정상군을 포함한 모든 실험군에서 비슷한 경향을 나타내었다. 천연복합물질의 섭취가 당뇨쥐의 내당능에 미치는 영향을 관찰한 경과 정상군의 경우 15분 후에 혈당이 최고치에 달하였고 90분 후에는 다시 공복 시 혈당수분으로 회복되었고 STZ-control군에서는 혈당이 60분 후에 최고치에 이르렀고 120분 후에도 공복 시 혈당치보다 현저히 높은 수준에 머물렀다. BG515-1군, BG515-2군 및 BG515-4군에서는 30분대에 가장 높은 수준에 달하였으며 120분 후에는 현저하게 감소되어 거의 공복전의 수준에 도달하였고 BG515-2군에서 가장 좋은 내당능 효과를 보였다. This study was designed to investigate natural medicinal plants-extracts (BG515), which are multi extracts of Mori Folium, Rehmannia glutinosa Liboschitz, Dioscorea japonica, Lycii fructus, and Astragalus Radix on blood glucose level and lipid metabolism in streptozotocin induced diabetic rats. The contents of carbohydrate in the natural medicinal plants extracts was 66.1g, crude protein was 14.5g, crude fat was 0.3g, ash was 11.7g, moisture was 7.4% per 100g edible portion. The contents of calcium in BG515 was 1503.96 mg, phosphorus was 468.31 mg, iron was 9.6 mg, sodium was 1.20 mg, and potassium was 2510.27 mg per 100g. 35 Male Sprague-Dawley (SD) rats weighing 150-170g each (6 weeks old) were randomly divided into one control (Group A) and 4 STZ-induced diabetic groups and subjected to one of the following treatment for 12 weeks. Group A and B were fed on basal diets and Group C, D and E received same diets as group A and B but additionally supplemented 150 mg/kg, 300 mg/kg, and 600 mg/kg of BG515 orally for 12 weeks, respectively. Diabetes of Group B, C, D and E were induced by intravenous injection of 45 mg/kg body weight of STZ in sodium citrate buffer (pH 4.5) via tail vein, respectively. Diabetic rats including BG515 administered groups showed the lower weight gain compared to the normal rats. but weight loss in STZ-control group is much stronger than BG515 groups. There were significant increases of feed-and drinking water consumption in all STZ-treated diabetic rats including BG515 administered groups compared to normal group. Especially, drinking water consumption in STZ-groups is increased with six fold in compare with control group. In BG515 -2 groups, showed the best of glucose challenge in normal and diabetic rats fed experimental diets.

객체지향성 웹 모델 프로세서 설계에 대한 연구

정혜옥,양동일,남윤성,박순희,최형진 강원대학교 정보통신연구소 2006 정보통신논문지 Vol.10 No.-

UML is able to visualize and specialize the output of the system center of the software, and able to connect to various languages and is constructed by engineering/re-engineering. Also, UML is a standard Modeling Language that aims at the documentation. Recently Web Application System is quickly popular and gigantic, it's possible to do modeling using UML which is the method of Object-Oriented analysis and design and simplify the complex developing course of software. In this paper, we suggest the 『Post Seminar System』 model for instance Object-Oriented Web Application which can increase the efficiency of businesses through of exchanging information with members. We constitute web application by separating it into 3 steps such as View class which takes full charge of Screen Presentation, controller which plays the role of connecting ring and divergence of View class and Model class, and Model class that takes charge in the gear with the Application Logic and DB applying MVC model which has considerable merit in developing and maintaining the web application.

백내장 수술환자 진료결과들간의 관계 : 사전 연구를 중심으로 Pilot study

박은철,김한중,홍영재,조우현,손명세,임승정,강형곤,최윤정 한국의료QA학회 1998 한국의료질향상학회지 Vol.5 No.1

Background : This study was done to assess the relationship among multiple patient outcomes of cataract surgery perioperatively, 3-4 months and 12 months after surgery. The patient outcomes include changes in visual acuity(operated eye, better eye), visual function(VF-14), patient satisfaction, subjective satisfaction with vision, and subjective overall health status. Methods : For the assessment of relationship, prospective study was performed with 92 patients who had undergone either one or both eye cataract surgery by 3 ophthalmologists practicing at a university hospital. Patients were interviewed, and clinical data were obtained. Doctors were questioned with self-entered questionnaire forms. Medical record was examined to understand surgery process. The survey was conducted at 4 stages : preoperatively, perioperatively, postoperative 3-4 months, and postoperative 12 months. Results : The correlations within patient outcomes at 4 stages - the visual acuity of operated eye and that of better eye, patient satisfaction and VF-14, subjective overall health status and relative health status as against others - were found to be positively correlated. The change in the visual acuity of operated eye and better eye was correlated with VF-14 as well as with patient satisfaction. The change was also correlated with overall health status. However, the correlations between variables were decreased as the postoperative period got longer. Conclusion : As for the postoperative clinical patient outcomes, VF-14 is acted to linker between visual acuity - clinical outcomes and overall health status - endpoint outcomes. Therefore, VF-14 is the index of patient-sided and disease-specific outcome for cataract surgery.

경골 골수정 고정술후 교합나사의 파단

박형빈,강번중,송해룡,구경회,정순택,조세현 대한골절학회 2002 대한골절학회지 Vol.15 No.4

목 적 : 경골 골절에서 골수정 고정술후 발생하는 교합나사 파단의 빈도와 발생 원인을 밝히고자한다. 대상 및 방법 : 1995년 3월부터 2000년 10월까지 골수정으로 치료하였던 경골 간부골절 82예중 내고정물 파단이 발생하거나 골유합이 이루질 때까지 추시 가능하였던 75예를 대상으로 하였다. 내고정물 파단 빈도와 위치, 골절의 양상, 술후 골절부 신연 및 골유합 이상 여부를 조사하였다. 결 과 : 교합나사 파단은 7예였고 (9.3%), 근위부 두 번째 나사의 파단이 가장 흔하였다. 교합나사으 ㅣ파단은 AO분류 B형과 C형 골절, 술후 골절부가 신연된 경우, 개발성골절, 자연유합 및 불유합의 경우 발생하였다. 결 론 : 교합나사 파단의 주된 요인은 골절부의 골과 골 접촉이 불안정하기 때문이며, 개방성 골절, 지연유합 및 불유합도 교합나사 파단의 위험인자라고 생각한다. 교합나사 파단을 예방하기 위해서는 수술시 골절부 신연을 피해야하며 골절부 골접촉이 불안정한 경우 완전 체중부하를 골유합시까지 제한하여야할 것으로 생각한다. Purpose : The aims of this study were to investigate the prevalence and the causes of crew breakage in tibia nailing. Materials and Methods : Between 1995 and 2000, eighty-two tibial diaphyseal fracture were treated with interlocking nails. The loss of follow-up was 7 cases. We retrospectively reviewed seventy-five cases. We investigated the rate and location of metal failure and evaluated the fracture pattern, the presence of distraction after nailing and union abnormality. Results : Screw breakage was identified in seven cases (9.3%) and most frequently occurred on the second proximal locking screw. Screw breakage occurred in AO type B or C type fractures, fracture site distraction after nailing, open fracture, delayed union and nonunion. Conclusion : The main cause of screw breakage is unstable bone to bone contact on the fracture site caused by comminution of distraction. The open fracture, delayed union, and nonunion also contributing factors for screw breakage. For preventing screw breakage, it is necessary to avoid fracture site distraction and delay full weight bearing in cases having unstable fracture site contact.

유전체의 과도 산란 해석을 위한 시간영역 결합 적분방정식

박재권,김형진,윤희상,정백호 湖西大學校工業技術硏究所 2003 工業技術硏究所論文集 Vol.22 No.-

In this paper, we propose a time domain combined field integral equation (TD-CFIE) formulation to analyze the transient electromagnetic response from three-dimensional dielectric objects. The solution method in this paper is based on the method of moments(MoM) that involves separate spatial and temporal testing procedures. A set of the RWG(Rao, Wilton, Glisson) functions is used for spatial expansion of the equivalent electric and magnetic current densities and a combination of RWG and its orthogonal component is used as spatial testing. We also investigate spatial testing procedures for the TD-CFIE to select the proper testing functions that are derived from the Laguerre polynomials. These basis functions are also used for temporal testing. Numerical results computed by the proposed formulation are presented and compared with the solutions of the frequency domain combined field integral equation(FB-CFIE).