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      • KCI등재후보

        唾液이 齒石形成에 미치는 影響 및 齒石內 칼슘과 隣의 定量分析에 關한 硏究

        金世勳 대한구강생물학회 1986 International Journal of Oral Biology Vol.10 No.2

        The purpose of this study is for determination of dental calculus forming factors, stimulation time and periodontal disease-related changes in paraffin stimulated whole salivary components and calcium/phosphorus ratio of supragingival and subgingival calculus from dental calculus formers with periodontal disease. For this study, total 22 persons were divided into two groups : experimental group were 10 patients with dental calculus and periodontal disease and control group were 12 dental students with well controlled oral hygiene. Paraffin-stimulated whole saliva was collected under clinical condition for first and second 5 minutes for determination of stimulating time-related change in two groups. Paraffin-stimulated saliva for total 10 minutes was used for determination of dental calculus forming factors and periodontal disease-related changes in two groups. Supragingival calculus and subgingival calculus were collected from patients with dental calculus and periodontal disease. Stimulated whole saliva was analyzed for pH, flow rte, protein, inorganic phosphorus, and calcium, and calculus was analyzed for calcium/ phosphorus ratio. The attained results were as follows; 1. A significant stimulating time-related increase in stimulated whole salivary pH was found in both experimental and control group(P <0.01). 2. A significant stimulating time and disease-related decrease in stimulated whole salivary protein was found between experimental and control group(P <0.05). 3. No significant stimulating time or disease-related difference in stimulated whole salivary calcium and inorganic phosphorus were found in/or between experimental and control group. 4. A significant difference in stimulated whole salivary flow rate, protein and pH were found between calculus formers with periodontal disease and non-calculus formers with well controlled oral hygiene(P <0.05). 5. Quantitative analysis have shown slight difference in the content of calcium between supragingival calculus and subgingival calculus. The Ca/P ratio of supragingival calculus is 1.82 while that of subgingival calculus is 1.72.

      • SCOPUSSCIEKCI등재

        당뇨 환자에서 경막외 농양과의 감별을 요한 원발성 척추 경막외 임파종 - 증례보고 -

        김세훈,임동준,조태형,정용구,이훈갑,이기찬,서중근,Kim, Se Hoon,Lim, Dong Jun,Cho, Tai Hyoung,Chung, Yong Gu,Lee, Hoon Kap,Lee, Ki Chan,Suh, Jung Keun The Korean Neurosurgical Society 2001 Journal of Korean neurosurgical society Vol.30 No.3

        척추 경막외 임파종은 전체 임파종의 7%정도를 차지하며, 가장 흔한 증상으로 척수 압박 증세를 유발하는 것으로 알려져 있다. 그 중에서도 원발성 척추 경막외 임파종, 즉 다른 장기의 침범 소견 없이 척추에만 국한되어 나타난 임파종은, 당뇨병 환자에서 급성 척수 압박 증상으로 나타났을 때, 척추 경막외 농양과의 감별을 요한다. 저자들은 48세의 여자 당뇨 환자에서 흉추부의 통증으로 내원 1개월 전까지 여러 차례 침술치료를 받고 난 후 통증이 악화되고 급성 하반신 부전마비와 배뇨 장애 및 감염 징후가 있어 본원에 내원하여, 병력과 제반 검사상 수술전에 척추 경막외 농양으로 진단되었던 원발성 척추 경막외 임파종 1례를 수술 치험하고 보고하는 바이다. Primary spinal epidural lymphoma(SEL), i.e. occurring in the absence of any detectable extraspinal lymphoproliferative disorder, is an unusual cause of spinal cord compression. The authors report a 48-year-old, diabetic woman presented with back pain followed by acute paraparesis and voiding difficulty. She had been treated with acupunctures on her back before admission, and complete blood count showed leukocytosis with neutrophilia and increased erythrocyte sedimentation rate(ESR). Thoracic spine magnetic resonance imaging(MRI) revealed an epidural mass extending from T5 to T8 with compression of the spinal cord. Emergency decompressive laminectomy was performed with a tentative diagnosis of spinal epidural abscess, but a B-cell lymphoma was final pathologic diagnosis. Further staging showed no other sites of lymphoma, and the spinal lesion was treated by chemotherapy and radiotherapy. The authors stress that primary SEL can mimic spinal epidural abscess(SEA) in the diabetic patient and should be a diagnostic consideration in patients with a syndrome of acute spinal cord compression manifested by a prodrome of back pain and neuroimaging consistent with an epidural compressive lesion, especially in a diabetic.

      • KCI등재

        단자속양자 소자에 있어서의 조셉슨 접합의 스위칭 오류

        김세훈,강준희,김진영,박종혁,임해룡,정구락,한택상 한국물리학회 2005 New Physics: Sae Mulli Vol.50 No.4

        In rapid single ux quantum (RSFQ) digital devices, the Josephson junctions are current biased and subject to thermally induced switching errors. In this research, we studied the switching errors of the Josephson junctions by measuring the bit error rate of an RSFQ switch. We prepared two identical circuits and placed them in parallel. The circuits had 10 Josephson transmission lines (JTLs) connected in series with an RSFQ switch placed in the middle of the 10 JTLs. We used a splitter to feed the same input signal to both circuits. The outputs of the two circuits were compared with an RSFQ XOR to measure the bit error rate. By using a computerized bit error rate test setup, we measured a bit error rate of 2.18 10က12 when the bias to the RSFQ switch was 0.398 mA, which was quite o from the optimum bias of 0.6 mA.

      • KCI등재
      • 귀밑샘의 기무라병의 세침흡인 세포학적 소견 -세포학적 검사로 예측할 수 없었던 1예 보고-

        김세훈,김혜령,김성은,양우익,이광길,홍순원,Kim, Se-Hoon,Kim, Hae-Ryoung,Kim, Sung-Eun,Yang, Woo-Ick,Lee, Kwang-Gil,Hong, Soon-Won 대한세포병리학회 2003 대한세포병리학회지 Vol.14 No.2

        Kimura's disease is a chronic inflammatory disorder of unknown cause and is most prevalent among Asians. The cytologic findings of Kimura's disease are significant numbers of eosinophils in a background of lymphoid cells, occasional fragments of collagenous tissue, proliferation oi vessels, and Warthin-Finkeldey polykaryocytes. Among these features, the most important cytologic feature of Kimura's disease is a significant numbers of eosinophils. We experienced a case of Kimura's disease in the parotid gland which we fatted to recognize on cytology due to the apparent paucity of eosinophils. On careful retrograde reviewing of the cytologic findings, a few scattered leukocytes, previously interpreted as polymorphous leukocytes, had bilobed nuclei and coarse green but granular cytoplasm on Papanicolaou preparation. These leukocytes showed obvious orange-red intracyloplasmic granules as in eosionophils on Giemsa stain. The paucity of eosinophils may be due to the thick fibrosis around lymphoid follicles or any technical error during aspiration. Whereas the Warthin-Finkeldey type giant cell is not a sensitive cytologic marker of Kimura's disease, it may be a helpful cytologic feature. To reach a correct cytologic diagnosis of Kimura's disease, It is important to keep in mind that searching for Warthin-Finkeldey type giant cells and evaluation of Giemsa stain for detection of eosinophils would be helpful.

      • 분비성 수막종의 입착도말 소견 -1예 보고-

        김세훈,이광길,김태승,Kim, Se-Hoon,Lee, Kwang-Gil,Kim, Tai-Seung 대한세포병리학회 2004 대한세포병리학회지 Vol.15 No.1

        Secretory meningioma is a distinct subtype of meningioma. We describe the cytologic features of a secretory meningioma on squash preparations, in comparision with other cytologic mimickers. A 54-year-old woman presented with hearing loss, vertigo, tinnitus, and headache for seven years. A brain MRI study revealed a 4.5cm sized mass in the cerebellopontine angle, which showed homogenous signal intensity in T2-weighted image. The intraoperative squash smear showed some well-defined, thin rimmed intracytoplasmic inclusions, containing a finely granular eosinophilic core among less cohesive meningiomatous cells. Histologic sections revealed a meningothelial meningioma with scattered inclusions, with periodic acid-Schiff, carcinoembryonic antigen, and cytokeratin positivity. Identification of characteristic intracytoplasmic inclusions is helpful for diagnosing secretory meningiomas. On squash preparations, differential diagnoses included tumors with inclusions or cytoplasmic vacuolizations, such as metastatic mammary infiltrating ductal carcinoma, gastric adenocarcinoma, hepatocellular carcinoma, and clear cell ependymoma, oligodendroglioma, hemangioblastoma, chordoma, and other variants of meningiomas (clear cell, xanthomatous, microcytic, and chordoid variants). In addition, the possibilities of glioma with eosinophilic granular body, and metastatic tumors from mammary infiltrating ductal carcinoma, gastric adenocarcinoma, and hepatocellular carcinoma in meningioma should be considered.

      • KCI등재

        한국인 희소돌기아교세포종의 1p/19q 이형접합소실 검사에 적합한 현미부수체 표지자

        김세훈,김호근,김태승 대한병리학회 2005 Journal of Pathology and Translational Medicine Vol.39 No.1

        Background : It is well known that oligodendrogliomas can be divided into two groups according to the 1p/19q or 1p loss of heterozygosity (LOH) status because oligodendrogliomas with the 1p/19q LOH or the 1p LOH have a better prognosis and chemosensitivity. In this study, we investigated the adequate microsatellite markers for 1p/19q LOH of oligodendroglial tumors in Korean patients. Methods : We performed PCR that was based on the LOH test with the 1p (D1S508, D1S199, D1S2734, D1S186 & D1S312) and 19q (D19S219, D19S112, D19S412 & D19S596) microsatellite markers; these were the markers that were recommended by other researchers. We performed this PCR on microdissected paraffin embedded tissue blocks of 67 tumors from 56 cases. Results : The PCR based LOH analysis revealed that 3 microsatellite markers (D1S508, D1S2734 & D1S186) of 1p and 2 markers (D19S219 & D19S412) of 19q had higher heterozygosity scores than other markers. In addition, chromosomal LOH status using these selective markers showed a statistically significant difference of prognosis for oligodendroglial tumors. Conclusions : We can suggest that the microsatellite markers with high heterozygosity scores (D1S508, D1S2734, D1S186, D19S219 and D19S412) would be adequate microsatellite markers for a PCR based LOH test of oligodendroglial tumors in Korean patients.

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