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박형래,이충국,김진,박소연,박형래 大韓顎顔面成形再建外科學會 1990 Maxillofacial Plastic Reconstructive Surgery Vol.12 No.2
Intraosseous carcinoma of the jaw may arise as metastatic lesions most commonly from breast, lung, kindney and thyroid and also primarily occur from ameloblastoma or odontogenic cyst. Rarely primary intraosseous carcinoma could be originated from the epithelium involved in odonotogenesis. According to WHO's classification, primary intraosseous carcinoma is defined as squamous cell carcinoma, occured in the Jaw without connection to the oral mucosa. However, Elzay defined primary intraosseous carcinoma as malignant epithelial tumor related to the odontogeni apparatus, including carcinoma exodontogenic cyst, carcinoma ex-ameloblastoma and carcinoma de novo. We experienced 2 cases of intraosseous carcinoma of the jaw. The first case, a 59-year-old man, showed a ill-defined mass on the left maxilla, measuring 8x10cm in size. He received radical hemimaxillectomy and was diagnosed as ameloblastic carcinoma. The second case obtained from a 79-year-old woman showed a ill-defined 6x8cm sized mass on the left mandibular body area. The mass was surgically removed by partial mandibulaectomy, which was diagnosed as the primary intraosseous carcinoma, probably odonotogenic origin.
천연 생약복합추출물이 Streptozotocin 유발 당뇨성 흰쥐의 장기무게 및 혈당내성에 미치는 효과
박형래,조정순 명지대학교 자연과학연구소 2006 자연과학논문집 Vol.25 No.-
상엽, 지황, 산약, 구기자 및 황기 등 5가지 천연복합추출의 일반성분 분석의 결과 100g 당 325 kcal이었으며, 수분함량 7.4%, 조지발 0.3g, 탄수화물 66.1g, 회분 11.7g이었다. 무기질 중 칼슘은 1503.96 mg, 칼륨은 2510.27 mg, 철분 9.68 mg, 소디움 1.20 mg이었다. streptozotocin(STZ)으로 당뇨를 유발시킨 흰쥐에 5가지 천연복합추출물(BG515)를 12주간 경구 투여한 후 다음과 같은 결과를 얻었다. 체중변화에서 실험군 모두에서 정상군에 비하여 유의적으로 낮은 체중증가를 나타냈었으며 BG515-4군에서 가장 낮은 체중증가 경향을 나타내었다. 평균 1일 식이섭취량 비교에서 STZ-control군을 포함한 실험군 모두에서 정상군에 비하여 현저한 증가를 나타내었으며 STZ-control군 및 천연복합물질 BG-515 투여군 사이에는 유의적인 차이는 없었다. 평균 1일 음수량 비교에서 당뇨가 유발된 STZ-control군을 포함한 실험군 모두에서 정상군에 비하여 6배 정도의 높은 음수량을 나타내었다. 신장과 간, 폐 및 심장조직의 중량은 STZ-control군을 포함한 실험군 모두에서 실험 전 기간에 걸쳐 정상군에 비해 상대적 중량이 유의적으로 높게 나타났으며 췌장의 중량도 정상군에 비해 실험군 모두에서 유의적인 증가를 나타내었으며, 비장의 중량은 정상군을 포함한 모든 실험군에서 비슷한 경향을 나타내었다. 천연복합물질의 섭취가 당뇨쥐의 내당능에 미치는 영향을 관찰한 경과 정상군의 경우 15분 후에 혈당이 최고치에 달하였고 90분 후에는 다시 공복 시 혈당수분으로 회복되었고 STZ-control군에서는 혈당이 60분 후에 최고치에 이르렀고 120분 후에도 공복 시 혈당치보다 현저히 높은 수준에 머물렀다. BG515-1군, BG515-2군 및 BG515-4군에서는 30분대에 가장 높은 수준에 달하였으며 120분 후에는 현저하게 감소되어 거의 공복전의 수준에 도달하였고 BG515-2군에서 가장 좋은 내당능 효과를 보였다. This study was designed to investigate natural medicinal plants-extracts (BG515), which are multi extracts of Mori Folium, Rehmannia glutinosa Liboschitz, Dioscorea japonica, Lycii fructus, and Astragalus Radix on blood glucose level and lipid metabolism in streptozotocin induced diabetic rats. The contents of carbohydrate in the natural medicinal plants extracts was 66.1g, crude protein was 14.5g, crude fat was 0.3g, ash was 11.7g, moisture was 7.4% per 100g edible portion. The contents of calcium in BG515 was 1503.96 mg, phosphorus was 468.31 mg, iron was 9.6 mg, sodium was 1.20 mg, and potassium was 2510.27 mg per 100g. 35 Male Sprague-Dawley (SD) rats weighing 150-170g each (6 weeks old) were randomly divided into one control (Group A) and 4 STZ-induced diabetic groups and subjected to one of the following treatment for 12 weeks. Group A and B were fed on basal diets and Group C, D and E received same diets as group A and B but additionally supplemented 150 mg/kg, 300 mg/kg, and 600 mg/kg of BG515 orally for 12 weeks, respectively. Diabetes of Group B, C, D and E were induced by intravenous injection of 45 mg/kg body weight of STZ in sodium citrate buffer (pH 4.5) via tail vein, respectively. Diabetic rats including BG515 administered groups showed the lower weight gain compared to the normal rats. but weight loss in STZ-control group is much stronger than BG515 groups. There were significant increases of feed-and drinking water consumption in all STZ-treated diabetic rats including BG515 administered groups compared to normal group. Especially, drinking water consumption in STZ-groups is increased with six fold in compare with control group. In BG515 -2 groups, showed the best of glucose challenge in normal and diabetic rats fed experimental diets.
A Study on the Ionogram Inversion Algorithm Using Mean Value Theorem
박형래,채종석,이혁재,Park, Hyung Rae,Chae, Jong Seok,Lee, Hyuck Jae The Institute of Electronics and Information Engin 1987 전자공학회논문지 Vol.24 No.2
A description of ionogram inversion algorithm developed for obtaining ionospheric electron density profile from ionospheric sounding datas (ionograms) in real time using mean value theorem is given and the methods for determining starting points and correcting valley effects are considered. The results derived from this algorithm are compared with the theoretically simulated datas, and the real electron density profiles from the measured ionograms taken at Radio research Laboratory in Korea are given to show its practical use.
Simultaneous Addition and Subtraction of Optical Images by Using the Extended Incoherent Source
박형래,전석희,박한규,Park, Hyung Rae,Jeon, Seok Hee,Park, Han Kyu The Institute of Electronics and Information Engin 1986 전자공학회논문지 Vol.23 No.6
A technique of optical image synthesis with an extended incoherent source is presented and compared with the coherent method. A holographic diffraction grating is fabricated by using Michelson interferometer, and by equalizing the 8th-order to the 2nd-order diffraction efficiency, complex amplitude addition and subtracdtion of optical images are simultaneously realized. The experiment shows that the quality of synthesized optical images in the incoherent method is improved in comparison with that of the coherent method by suppressing the coherent artifact noise.