Gα^(h)-단백질에 의해 활성화되는 Phospholipase C 이소효소의 확인

조강호,박권식,채규영,한기정,김형석,김형일,윤혜영,권년수,이희성,백광진 중앙대학교 의과대학 의과학연구소 2000 中央醫大誌 Vol.25 No.4

초등학교 교사들의 직무스트레스와 건강 수준

조현숙,이종태,손혜숙,박진국 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objective : The purpose of this study was to assess the effect of job strain on stress and health status among elementary school teachers. Methods and Material : The subjects in this study were 300 teachers who were selected from among 588 teachers in 13 out of 42 elementary schools in the city of Gimhae. Through the questionnaire, demographic characteristics, Karasek's Job Content Questionnaire(JCQ) and the Psychosocial Well-being Index (PWI) to assess their occupational characteristics and psychosocial stress level were surveyed. Medical checkup results of them were adopted to measure their Health status. Results : 24.9 percent of the general teachers were low strain group, and 16.3 percent of them were high strain group. In the senior teachers, 19.7 percent belonged to a low strain group and 21.3 percent belonged to a high strain group. In regard to health status, more senior teachers than junior teachers suffered from obesity(24.6%) and diabetes(11.5%) (p<0.O5), and they also were higher in DBP(p<0.057), total cholesterol(p=0.039) and blood sugar level(p=0.000), the low strain group perceived more social support(p=0.000), and the high strain group felt bigger physical overload(p=0.000). Concerning psychosocial stress, the low strain group was more aware of teacher social role and put more confidence in themselves(p=0.004). The high strain group was more depressed(p=0.001), but no difference was detected in health status. The health status difference between the high strain and low strain groups was significant in depression of psychosocial stress(OR=3.823, 95%CI=1.584-9.224). Conclusion : The senior teachers group was more morbid to obesity, diabetes and hyperlipidemia, which implies that some measure should be studied to help senior teachers manage those diseases properly. The high strain group suffered more from physical overload and was high 'Social support'. Therefore it's required for high strain group to be given more support from colleagues and supervisors, and a stress management program should be implemented to reduce their psychosocial stress.

젊은 성인 남자의 흡연과 혈청 지질과의 관련성

조선,류소연,박종,강명근,김은숙,김형철,박광희,윤혜은,노희송 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Objectives: This study was performed to find the association of cigarette smoking and blood lipid profiles in healthy young adults. Methods: The data was collected by a self-administered questionnaire and health examination in 489 professional soldiers from 6 to 12 May, 2004. The status of cigarette smoking was classified by non-smoking, ex-smoked, ≤4.9, 5-9.9, and ≥10 pack-years. The statistical analysis were used by chi-square test, analysis of variance and analysis of covariates. Results: In status of subjects cigarette smoking, current smoking, ex-smoked, and non-smoking were 71.8%, 11.2%, and 17.0%, respectively, In distribution by amount of smoking, non-smoking, ex-smoked, ≤4.9 pack-years, 5-9.9 pack-years, and ≥10 pack-years were 17.0%, 11.2%, 37.4%, 21.3%, and 13.1%, respectively. At other confounding variables were controlled, total cholesterol and LDL-cholesterol were increased significantly when amount of smoking was increased. However, triglyceride and HDL-cholesterol did not showed statistically significant differences, Conclusion: Smoking has relevant to total cholesterol and LDL-cholesterol and it is need to perform the further study for finding how blood lipid profiles are affected its level by cigarette smoking and to find an influence of cigarette smoking on cardiovascular disease.

加熱한 牛肉의 部位別 아미노酸 組成과 그 蛋白質의 品質評價

權貞淑,李惠成 慶北大學校 産業開發硏究所 1984 硏究報告 Vol.12 No.-

This study was conducted to analyze the amino acid composition and available lysine and to evaluate the protein quality of several parts of the cooked beef. The parts of beef used were foreshank, ox-tail and ox-stomach. Raw samples were prepared by Korean meat soup cooking method and freeze drying and amino acid composition and available lysine were measured. Protein quality was evaluated from chemical score, biological value and available lysine content of each sample. The main findings of this study will be summarized as follows: Overall distribution of amino acids in different parts of beef were almost the same. Generally, samples contained large amount of Glycine, Glutamic acid,Aspartic acid and small amount of Tryptophane, Methionine and Histidine. It was shown that foreshank part contained the highest amount of total essential amino acids and ox-tail part had the least. Especially it was interesting to note that ox-tail part had high amount of Glycine, the major component amino acids of incomplete protein, collagen. It also has been found that some amino acid such as Tryptophane were fairly reduced by boiling in foreshank part. On the other hand, Arginine, Proline, Glycine, Alanine were increased. Chemical score and biological value of boiled ox-tail part were remarkbly low compared with other parts. Availability of lysine was high in the order of ox-tail>raw foreshank>ox-stomach. Total lysine and available lysine contents were reduced by boiling.

서울 시내 4년제 남자 대학생의 우울과 흡연량, 흡연기간, 니코틴 의존도와의 관계

박지영,박소영,이미숙,백수진,신의경,예혜련,오승진,장윤정,조혜진,김수지 이화여자대학교 간호과학대학 2003 이화간호학회지 Vol.- No.37

Background: With reports on the relation between smoking and depression appearing since 1980, it has become clear that depression is one of the psychodynamics of smoking, though there has been little or no progress made in the study of whether or not there is indeed a relation between depression and nicotine dependence. Purpose: The purpose of the study was to investigate the effects of depression on the amount and period of smoking and nicotine dependence among university man student smokers. Method: In periodical examination between 14 and 21, May, 2003, using 170 university male. The CES-D(Center for Epidemiologic Studies Depression) Scale and the FTQ(Fagerstrom Tolerance Qustionnaire) were utilized to measure the level of depression and nicotine dependency. The amount of smoking was calculated based on the number of cigarette used. Result: Results indicated that depression had something to do with amount of smoking. Nicotine dependence also was related to depression but total value was relatively low. finally the period of smoking had nothing to do with depression. Conclusion: The results of this study revealed that the amount of smoking of university man student smokers was very high. Both the amount of smoking and nicotine dependence were affected by levels of depression. Accordingly psychiatric nursing access such as emotional support is needed to manage depression and decrease smoking.

유방암의 위와 대장전이

유현아,김은영,서민지,정은,조민정,오현진,장지혜,박지찬,이정의,박석영 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.2

Gastric metastasis from breast cancer is rare and only six cases have been reported in Korea. Colon metastasis is more rare than gastric metastasis. We report a 63-year-old woman with gastric and colon metastases of invasive lobular carcinoma of breast. She was diagnosed as right breast cancer, received right modified radical mastectomy 10 years ago and has been treated with chemotherapy and hormone therapy. Investigating for melena and a small caliber of stool, we found gastric and colon metastases. The diagnosis of metastatic breast cancer was made through gross pathologic and immunohistochemistry staining. We report a case with gastric and colon metastases from breast cancer and a review of the associated six case reports in Korea.

Poster Session:PS 0231 ; Gastroenterology : Tenofovir-Associated Nephrotoxicity in a Patient with Chronic Hepatitis B: A Case Report

( Hye Ki Cho ),( Yu Ri Cho ),( Jeong Hoon Lee ),( Su Jong Yu ),( Kook Hwan Oh ),( Kyoung Bbun Lee ),( Jung Hwan Yoon ),( Hyo Suk Lee ),( Yoon Jun Kim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Tenofovir disoproxil fumarate (TDF) is an effective agent for chronic hepatitis B (CHB) infection as well as human immunodeficiency virus (HIV) infection, and its use is rapidly increasing worldwide. It is now established that TDF is associated with renal toxicity in HIV-infected patients, while severe or symptomatic TDF-associated nephrotoxicity has been rarely reported in patients with CHB. Here, we present a patient with TDF-associated nephrotoxicity who was being treated for CHB infection. Five months after starting TDF treatment, the patient was found to have clinical manifestations of proximal renal tubular dysfunction and histopathologic evidence of acute tubular necrosis. The patient`s renal function improved markedly after TDF was discontinued. Finally, we discuss the risk factors of TDF-associated renal toxicity and present recommendations for monitoring renal function during TDF therapy.

Development of Home Care Quality Indicators (HCQIs) at Demonstration Project of Elderly Care Insurance Program in Korea

Cho Ja Kim,Yon Soon Kim,Hae Young Kang,Myung Sook Sung,Young Ja Woo,Hyun Suk Oh,Yeung Ok Yoon,Cho Hye Sook,Jeong Hye Park,Young Hee Ju 한국간호과학회 2007 한국간호과학회 학술대회 Vol.2007 No.11

Soybean transgenic plants with Coat protein and HC-Pro using RNAi method showed enhanced resistant to Soybean mosaic virus (SMV)

Hye Jeong Kim,Su Yeong Yun,Hyun Suk Cho,Yoon Jeong Lee,Hyun Hee Im,Yeong Hoon Lee,Ki Hyun Ryu,Kook-Hyung Kim,Young Soo Chung 한국육종학회 2014 한국육종학회 심포지엄 Vol.2014 No.07

Soybean mosaic virus (SMV), a member of Potyviridae family, is one of the most typical viral diseases and results in yield and quality loss of cultivated soybean. Due to the depletion of genetic resources for resistance breeding, a trial of genetic transformation to improve disease resistance has been performed by introducing SMV-CP and HC-Pro gene by RNA interference (RNAi) method via Agrobacterium-mediated transformation. Transgenic plants were infected with SMV strain G5 and investigated the viral response. As a result, two lines (3 and 4) of SMV-CP(RNAi) transgenic plants and three lines (2, 5 and 6) of HC-Pro(RNAi) transgenic plants showed viral resistance. In genomic Southern blot analysis, most of lines contained at least one T-DNA insertion in both SMV-CP(RNAi) and HC-Pro(RNAi) transgenic plants. Subsequent investigation confirmed that no viral CP and HC-Pro gene expression was detected in two SMV-resistant lines of SMV-CP(RNAi) and three lines of HC-Pro(RNAi) transgenic plants, respectively. On the other hand, non-transgenic plants and other lines showed viral RNA expression. Viral symptoms affected seed morphology, and clean seeds were harvested from SMV-resistant line of SMV-CP(RNAi) and HC-Pro(RNAi) transgenic plants. In addition, strong viral gene expression was detected from seeds of SMV-susceptible non-transgenic plants and SMV-susceptible transgenic lines. When compared the viral resistance between SMV-CP(RNAi) and HC-Pro(RNAi) transgenic plants, soybean transgenic plants with the HC-Pro gene using RNAi strategy showed much stronger and higher frequency of viral resistance.

TOWARD A NEXT GENERATION SOLAR CORONAGRAPH: DIAGNOSTIC CORONAGRAPH EXPERIMENT

Cho, Kyung-Suk,Yang, Heesu,Lee, Jae-Ok,Bong, Su-Chan,Kim, Jihun,Choi, Seonghwan,Park, Jongyeob,Cho, Kyuhyoun,Baek, Ji-Hye,Kim, Yeon-Han,Park, Young-Deuk The Korean Astronomical Society 2020 Journal of The Korean Astronomical Society Vol.53 No.4

The Korea Astronomy and Space Science Institute (KASI) has been developing a next-generation coronagraph (NGC) in cooperation with NASA to measure the coronal electron density, temperature, and speed simultaneously, using four different optical filters around 400 nm. KASI organized an expedition to demonstrate the coronagraph measurement scheme and the instrumental technology during the 2017 total solar eclipse (TSE) across the USA. The observation site was in Jackson Hole, Wyoming, USA. We built an eclipse observation system, the Diagnostic Coronal Experiment (DICE), composed of two identical telescopes to improve the signal-to-noise ratio. The observation was conducted at four wavelengths and three linear polarization directions in the limited total eclipse time of about 140 seconds. We successfully obtained polarization data for the corona but we were not able to obtain information on the coronal electron temperature and speed due to the low signal-to-noise ratio of the optical system and strong emission from prominences located at the western limb. In this study, we report the development of DICE and the observation results from the eclipse expedition. TSE observation and analysis with our self-developed instrument showed that a coronagraph needs to be designed carefully to achieve its scientific purpose. We gained valuable experience for future follow-up NASA-KASI joint missions: the Balloon-borne Investigation of the Temperature and Speed of Electrons in the Corona (BITSE) and the COronal Diagnostic EXperiment (CODEX).