지리산 국립공원 해발 865 m 지점에서 대기에어로졸입자의 입경별 질량농도 특성

류혜지 ( Hye-ji Ryu ),박정호 ( Jeong-ho Park ) 한국환경과학회 2017 한국환경과학회지 Vol.26 No.1

Aerosol mass size distributions were investigated at 865 m high the of Jirisan national park. A nanosampler cascade impactor was used to collect aerosols. The atmospheric aerosol particles had a unimodal mass size distribution, which peaked at 0.5-1.0 μm, and a mass aerodynamic diameter of 1.13 μm. The ann ual average concentrations of TSP, PM₁₀, PM_2.5, PM1, PM_0.5 and PM_0.1 were 20.9 μg/㎥, 19.3 μg/㎥, 14.9 μg/㎥, 10.7 μg/㎥, 5.3 μg/㎥, 1.2 μg/㎥, respectively. TSP concentrations were below 30 μg/㎥ during the sampling period. On average PM₁₀, PM_2.5, PM₁, PM_0.5 and PM_0.1 made up 0.91, 0.70, 0.41, 0.19 and 0.07 of TSP, respectively. The annual average of PM_2.5/PM₁₀ ratio was 0.77.

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

Inhibitory Effect of Cordycepin on Human Platelet Aggregation

박화진,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

Cordycepin separated from Cordyceps militaris is a major physiologic active component in Cordyceps militaris. The platelet aggregation is stimulated by Ca^(2+), which is either mobilized from intracellular endoplasmic reticulum or transported from extracellular space. cGMP antagonizes the actions of Ca^(2+). Based on these facts, we have investigated the effects of cordycepin on the mobilization of Ca^(2+) and the production of cGMP on collagen (10 ㎍/ml)-induced human platelet aggregation. Cordycepin potently stimulated the human platelet aggregation induced by collagen (10 ㎍/ml) in a dose-dependent manner. Cordycepin (500 μM) inhibited also the collagen-induced human platelet aggregation in the presence both 1 mM and 2 mM of CaCl_(2). These are in accord with the results that cordycepin inhibited the Ca^(2+)-influx on collagen-induced human platelet aggregation. These results suggest that cordycepin decrease the intracellular Ca^(2+) concentration to inhibit collagen-induced human platelet aggregation. Besides, cordycepin increased the level of cGMP on collagen-induced human platelet aggregation. This result is related with the decrease of intracellular Ca^(2+) concentration, because cGMP inhibits the mobilization of Ca^(2+). In addition, cordycepin inhibited the human platelet aggregation induced by LY-83583, inhibitor of guanylate cyclase. This result suggested that cordycepin inhibit the platelet aggregation by stimulating the activity of guanylate cyclase. In conclusion, we demonstrated that cordycepin might have the antiplatelet function by inhibiting Ca^(2+)-mobilization via the stimulation of the production of cGMP.

방사선 치료를 받는 암 환자들의 사회적 지지와 삶의 질과의 관계

정주희,류소연,윤혜은,남택근,오윤경,안현옥,박계남,이영선 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

Objective : This study was performed to investigate the relationship between social support and quality of life among cancer patients receiving radiation therapy. Matehals and Methods : The data were collected from 98 patients, who were receiving radiation therapy at two university hospitals located in GwangUJu, used by structured questionnaire. For statistical analyses of the association between quality of life and various characteristics, data were analyzed using t-test, ANOVA, Pearson 's correlation, and multiple regression analysis. Results: 1. There were 56(57.1%) males and 42(42.9%) females. Age ranged from 21 to 82 years. The primary sites of cancer were gastrointestinal tract (24.5%), lung (23.5%), breast (21.4%), and head and neck (11.2%) in order. 2. The mean scores of social, family, and medical support were 4.30 0.58, 4.49 0.78, 4.11 0.65, respectively. The score of quality of life was 5.83 1.63 (range: 1.95 ~ 9.05). 3. An analysis of the association between several factors of patients and quality of life showed that the statistically significant factors were age, the presence of distant metastasis, family support, medical support and social support. 4. As a result of the multiple regression analysis, only social support was significant (β=0.932, P=0.02) with quality of life, but age and presence of distant metastasis were not significant. Conclusion : This suggests that quality of life in cancer patients could be improved by strengthening the social support which consists of family and medical support. Further study would be necessary to evaluate separately several aspects of quality of life among cancer patients.

Cellulase 생산 야생효모의 선별 및 세포외 Cellulase 생산

문정수, 박경서, 김혜원, 김수진, 이종수 배재대학교 자연과학연구소 2016 自然科學論文集 Vol.33 No.1

자가공명영상을 이용한 정신분열병 환자의 뇌량 면적 측정

박홍석,이정섭,황성혜,김창현 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

연구목적 : 본 연구에서는 정신분열병의 병태생리에 뇌량이 관여하는지 확인하기 위해 초발 및 만성 정신분열병 환자, 대조군의 뇌량의 영역을 측정하였다. 방 법 : 국립의료원에 입원한 23명의 정신분열병 환자(남자 15명, 여자 8명)와 단순 두통 또는 어지럼증을 호소하여 내원한 23명의 외래환자를 대조군으로 하여 뇌자기공명영상을 얻었으며, 남자는 26명, 여자는 20명 이었다. 환자군중 초발군은 13명, 만성군은 10명이었다. 정중시상평면에서 뇌량을 7개 영역으로 구분하여 NIH Image 1.60프로그램으로 분석하였으며, 정중시상평면의 대뇌면적도 구하였다. 이렇게 구한 각 뇌량척도들은 t-test를 이용하여 대조군과 비교하였으며, 성별에 따른 차이는 ANOVA를 이용하였으며, 이후 대뇌면적을 공변량으로 하여 ANCOVA를 시행하였다. 또한 초발군과 만성환자군, 대조군의 비교는 나이와 대뇌면적을 공변량으로하여 MANCOVA를 시행하였다. 결 과 : 환자군과 대조군 사이의 총뇌량의 평균면적과 각 7부분의 평균면적을 비교한 결과 환자군이 제 3, 제 6 뇌량영역을 제외하곤 대조군에 비해 평균면적이 작은 것으로 나왔지만 통계적 유의성은 없었다. 성별에 따라 비교한 결과 통계적 유의성은 관찰되지 않았지만 남자환자는 대조군에 비해 작고, 여자환자의 경우에는 큰 것으로 확인됐다. 초발과 만성환자군으로 나누어 대조군과 비교해 본 결과, 통계적 유의성은 없었으나 초발환자군이 만성환자군에 비해 모든 뇌량척도가 작았고, 만성환자군은 대조군보다 총뇌량의 평균면적이 컸으나 초발군은 대조군 보다 작았다. 결 론 : 본 연구의 결과 정신분열병 환자에서 유의한 뇌량의 형태적 이상을 확인하지는 못했지만 이전 연구들에서도 다양한 결과들을 보고하고 있으며, 이는 정신분열병이 생물학적 및 임상적으로 각기 다른 표현형을 가지고 있다는 가설로 설명할 수 있다. Objectives : This study was performed to determine whether the corpus callosum is involved in pathophysiology of schizophrenia and measured corpus callosal areas of first episode, chronic schizophrenic patients and controls. Methods : We obtained the brain magnetic resonance imaging of 23 schizophrenic inpatients(15 males, 8 females) and 23 controls(11 males, 12 females) with simple headache or dizziness. Among the schizophrenic group, first episode patients were 13, chronic patients were 10. In mid-sagittal plane, the corpus callosum was divided into 7 areas and the cerebral area was measured. This data was analyzed with NIH image 1.60 software. We compared the corpus callosal areas of schizophrenics with controls by t-test and by ANOVA according to sex. Thereafter, ANCOVA was performed with mid-sagittal cerebral area as covariant. Comparison of first episode, chronic schizophrenics and controls was carried out by MANCOVA that was adjusted with age and mid-sagittal cerebra area. Results : The schizophrenics, compared with controls, had smaller corpus callosal areas except for the 3rd, 6th callosal area, but statistical significance was absent. According to sex, male schizophrenics had insignificantly smaller total callosal areas than male controls and female schizophrenics had larger ones. In comparison of first episode, chronic schizophrenic patients and controls, first episode patients had smaller every corpus callosal areas than chronic ones, chronic ones had larger total callosal area than controls and first episode ones had smaller total area than controls, but statistical significances were absent also. Conclusion : Our study did not reveal the structural abnormality of corpus callosum in schizophrenic patients, but many controversial results have been reported in other studies. This inter-study inconsistency could be explained by the hypotheses of not only clinical but also biological different phenotypes within the schizophrenia.

대학생을 위한 리더십향상 집단상담 구안 및 효과 연구

박현주,김민정,임진,엄혜련 西江大學校 學生生活相談硏究所 2005 人間理解 Vol.26 No.-

현대사회에서의 리더십은 크게 셀프리더십, 팔로워십, 능력부여리더십, 서번트리더십으로 분류될 수 있다. 한국의 대학생은 향후 인생의 목표를 설정하고 계획하여 추진하고 더불어 공동체의 일원으로 서로 교류하고 성장 한다는 발달적 과제를 가지고 있다. 따라서 대학생의 리더십은 셀프리더십을 바탕으로 한 자기관리, 대인관계 관리, 공동체 참여로 구성된다. 본 연구에서는 대학생의 리더십을 향상시키기 위한 집단상담을 구안하였으며 구조화된 대학생 리더십향상 집단상담을 2005년 1월에 실시하였다. 참여한 총 10명의 집단원들을 대상으로 집단상담 전 후에 각 구성요소를 측정하는 설문조사를 실시하였으며, 통계적으로 유의미한 차이는 아니었으나 자기관리, 대인관계관리, 공동체참여 각 영역 모두에서 향상된 양상을 보였다. 또한 집단원들의 회기별 피드백을 토대로 본 프로그램의 효과를 검증하였으며 본 프로그램의 보다 효과적인 적용을 위한 논의를 덧붙였다. Leadership, nowadays, can be classified into four different kinds: self-leadership, followership, empowering-leadership, and servant leadership. Korean university students have developmental tasks as members of group such as setting a life goal, making a plan, making an action, associating with others, and being advanced. Therefore, the elements of leadership program for university students based on self-leadership are self management, interpersonal relationship management, and participating in a group. In this study, a structured program for developing leadership of university students was designed, and operated on Jan, 2005. Surveys which measured each elements of the program were given to ten students who were participated in a group before and after the program. A statistical result was not significant. However, each elements, self management, interpersonal relationship management, and participating in a group, showed a progress. Session reviews by students were also used to verify the effect of the program. Further suggestions and studies for more effective application of the program were discussed.

前腕部 經穴 取穴에서 骨度分寸法과 一夫法의 比較 硏究

박히준,채윤병,차웅석,박종배,이혜정,이향숙,인창식,고형균,김수영,최일환,김강식,문정배,배기태,유경환,육근영,정병주,손인철,임사비나 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2004 東西醫學硏究所 論文集 Vol.2004 No.-

Background : The cun measurement System, an essential and convenient method in locating acupoints, has been widely used in the practice of acupuncture. However, traditional cun measurement has been criticized for its lack of reliability. Objectives : The purposes of this study are to determine if one cun measured by the directional methods have a consistency with that of proportional methods and to investigate which factors are related with these differences, especially in forearm. Methods : The distance between the elbow crease and the wrist crease of forearm was compared to a reference value of one cun obtained by the directional method. In this method, one cun is one third of the distance between index finger and Small finger of a subject, measured at proximal interphalangeal joint. In addition, to investigate the factors influencing the differences between these two methods, we measured the height and body weight and calculated body mass index (BMI). Finally we analyzed the factors correlated with these lengths by linear regression test. Results : The results showed that one cun obtained by the directional methods were significantly different from one cun by the proportional methods in forearm. It was demonstrated that the length acquired with the directional method was more correlated with body weight and body mass index, while the length obtained by the proportional method was more correlated with the height.

保護觀察 職員의 業務滿足度에 관한 調査硏究

朴在允,金惠正 國民大學校 法學硏究所 2002 법학논총 Vol.14 No.-

Die vorliegende Arbeit wird sich mit der Untersuchung der Problematik eines Bewa¨hrungssystems durch eine berufliche Zufriedenheit der Bewa¨hrungshelfer in Korea befassen. Fu¨r diese Arbeit wurde eine Umfrage (ein Fragebogen fu¨r gesamte Bewa¨hrungshelfer in Korea) gcstellt. Seit 1989 betrifft die Unterstellung unter dem Bewa¨hrungshelfer gegen jugendliche Krirninalta¨ter vor allem die Riskofa¨lle, bei denen tine giinstige Prognose nur infolge der zur Verfu¨gung gestellten Hilfe and Betreuung gestellt werden kann. Und seit 1997 wird sie gegen Erwachsenenta¨ter erweitert. Seitdem wa¨chst eine Anzahl der Bewa¨hrungshilfe erstaunlich zu. Im Jahr 2000 wurden 90,431 Personen eine Strafaussctzung bzw. Strafrestaussetzung zur Bewa¨hrung beurteilt. Problematisch ist, daB ein Bewa¨hrungshelfer eine Doppelfunktion hat; einerseits soil er dem Verurteilten helfend and betreuend zur Seite stehen, anderseits ist er jedoch verpflichtet, daB er den Verurteilten kontrollicren soli. Aber eine Bezichung zu dem einzelnen Tater kann in der Regel nicht sehr intensiv sein, weft ein Bewa¨hrungshelfer inn Druchschnitt ca. 300 Probanden gleichzeitig zu bewa¨chen and zu betreuen hat. Nach dem Ergebnis der Umfrage sind gegenwa¨rtige Situationen der Bewa¨h ungshilfe Behr niedrig. - Z.B., hauptliche Bewa¨hrungshelfer sind sehr wenig and eine Finanzierung von der Regierung fur die Bewa¨hrungshilfe ist sehr niedrig usw.. - Damit sind die meisten Bewa¨hrungshelfer mit ihrer Arbeit unzufrieden. Sie kritisieren solche schlechten Situationen. Trotz solcher schlechten Situation muJ3 ein Bewa¨hrungssystem weiter entwickelt werden. Dafur kann/soll eine privatliche verfugbare Arbeitskrafte and materielle Quelle entwickelt and breit angewandt werden.

교육용 소프트웨어 개발에 적합한 하이퍼미디어 시스템에 관한 연구

박성한,정혜윤,한민규,심진석 한양대학교 공학기술연구소 1993 공학기술논문집 Vol.2 No.1

This paper presents a back-end system of hypermedia authoring system for courseware development. For the design, repersentative hypertext reference models, the Dexter model and the HAM(Hypertext Abstract Machine) which belongs to Campbell & Goodman model were analyzed. Based on those models, data objects, attributes, and operations of back-end system were designed and implemented. Because the application area of this system is on computer based education, the path mechanism is enforced for the various educational strategies. In order to reduce the user disorientation and cognitive overheads in navigating hypernetwork, filtering, backtracking and history mechanism were implemented.