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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
Chun, Yoon-Keun,Ha, Joo-hun,Hong-Jung-Woo,Oh, Soo-Myung,Kim, Sung-Soo 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1
Yoon-Keun Chun¹,Joohun Ha□Hong-Jung Woo□, Soo Myung Oh□,Sung Soo Kim□ ¹Department of Molecular Biology, College of Medicine,²Department of Surgery, college of Medicine,³Department of Internal Medicine, College of Oriental Medicine,and ⁴East-Weat Medical Reserch Institute,Kyung Hee University, Seoul, Korea. The HBV DNA Amounts in Serum Have No relationship with ALT level and Hetergeneous Population Coexits in Chronic Hepatitis B Virus Infection. Proceedings of International Symposium on East-West Medicine, Seoul. 212-230, 1999. -Hepatitis B is caused by hepadnavirus. Hepatitis B virus replicates through 3.5kb pregenomic RNA intermediate which is regulated by core promoter. Pathogenesis of hepatitis B virus has been bilieved the result of host immune response. But recently many studies have reported that high level of viral replication caused by mutation in core promoter might result in severs hepatitis. But these studies were performed in vitro, not in vivo. So there is yet debate about which factor, viral of host factor, is more important in pathogenesis of hepatitis B virus. So we measured real viral replication level in 204 chronic hepatitis B patients by quantifying HBV DNA from sera by our novel PCR-based more sensitive method, and compared these results with ALT level measured from same sera, which indicates liver cell damage. Surprisingly there are no significant correlation between HBV DNA quantity and ALT level. Then we cloned core promoter region. In SSCP, we found that many viral mutants coexist in one patient. Base on SSCP result, we chose main viral core promoter type in each patients, which is thought to determine overall viral replication level in this patient. Main type of core promoter region of each 41 patients were directly sequenced. And with these we measured promoter activity by luciferase assay system and compared promoter activity with on another. We found tha there were some differences in promoter activity according to core promoter sequences. And we constructed replication-competent viral constructs with core promoter from 41 patients and Transfected these into HepG2 cell and measured HBV DNA by southern blot. There were also differences in HBV DNA quantity according to core promoter sequences. On these all results we investigated correlation between the effect of HBV core promoter on viral replication in vitro and HBN DNA quantity, ALT level from sera of each patients. We found there is no significant correlation among them. As a result, we concluded that in determining severity chronic hepatitis B patients, host factors of each patient is more important rather than replicative activity of virus itself.
信號交叉路의 交通特性과 左回轉 禁止에 따른 運營效果에 관한 硏究
홍익상,공창환,정우영,임채문 대구대학교 산업기술연구소 1993 産業技術硏究 Vol.12 No.-
This study analyzed the characteristics of the operation of left turns at intersections of the streets in Taegu City. The points of the study were as follows: increase of traffic capacity, decrease of delay time, and to do so this study aims at seeking a way for the most appropriate signal cycle and an effective way to operate intersections. The following are the results: 1st The arterials of Taegu City have a high rate of left turns, and yet are not divided into specific functions, which impairs the efficient use of the functions. It is required that a study be made on the way of utilizing the left turn to the maximum of the operational functions of signalized intersections. 2nd As traffic volume and left turn ratio increase, it was revealed that the optimum signal cycle and delay increased, adoption of efficient lanes was analysed to be most effective at the intersection which have a great of traffic volume and a high or rate of left turns. 3rd On the independent intersection in Taegu city, when left turn is prohibited, it may give poor approaches, but according to analyses this will bring a phenomenal decrease in the optimum signal cycle and delay.
禹洪九,鄭容相 건국대학교 1996 學術誌 Vol.40 No.1
In modern society the negotiability of a bill should be guaranteed in order to carry out its native function. There are defence, the institution of the good faith purchase of a bill, and the separate rule of a bill action for it. Because of these institutions, the negotiability of the transactions of a bill is promoted. It's important to protect both the negotiability of a bill and the debtor of a bill. The harmony of interests between the creditor of a bill and the debtor of a bill is guaranteed under the law of Bill. The institution of the good faith purchase of a bill is to harmonize between the creditor of a bill and the debtor of a bill. In Korea the institution of the good faith purrchase of a bio originated from the institution of the good faith purchase of chattel historically. But the good faith purchase of a bill is easier than that of chattel based on Civil law. The conditions of the good faith purchase of a bill are as follows. Firstly a bill should be obtained by the method of the law of a Bill. Secondly the indorsement of a bill should be continued. Thirdly a bill should be acquired by a rightless person. Fourthly the purchaser of a bill should have no bad faith and gross negligence. Fifthly there should be personal economic interests in association with the purchase of a bill. In this thesis a writer is inclined to examine whether a bill is obtained from a rightless person or the good faith purchase of a bill is recognized in case of defect of purchase of a bill(eg.assignor's disability, rightless agency, defect of manifestation of intention)with the exception that an assignor is a rightless person. In this connection there are serious conflicts of theories for it. A writer supports the position to recognize the good faith purchase of a bill restricted a rightless person on the basis of interpretation of the current Law of a Bill, general provision of private law and realization of legal stability The system of this thesis is as follows. 1.Introduction. 2.The controversies concerning scope of defect. A writer briefly introduces legislative examples concerning the good faith purchase of a bill, analyzes the controversies concerning the scope of defect in Korea, Japan and Germany through theories and cases. 3.Conclusion A writer analyzes the basic background of controversies concerning the scope of defect, presents a legal interpretation and legislative opinion.
홍상표,구성회,우세홍,김을환,최한영 서울보건대학 1997 서울보건대학 부설 한국보건과학연구소 논문집 Vol.4 No.1
LHR(Landfill Site Hazard Ranking Model)was developed for assessing the relative hazard of landfill sites by using the method of value-structured approach. LHR consists of combining a multiattribute decision-making method with a qualitative risk assessment approach. AHP(Analytic Hierarchy Process)based on the pairwise comparison method was applied to determine weights of landfill site factors related. To determine the relative hazard of landfill sites evaluated, hydrogeological factors, waste characteristics factors and recptors factors were evaluated by LHR. LHR can help decision-makers prioritization of remediation of landfill sites through the relatively convenient and concise evaluation metl10d of landfill site features related. LHR focuses mainly on pathways of groundwater and surfacewater for evaluating landfill hazard to receptors including humans. To validiate the applicability of LHR, Nanjido Landfill site, Metropolitan Landfill site, and Hwasung Landfill site were evalulated. LHR scores of the above-mentioned landfills were 55, 19, and 7 respectively.