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김보영 ( Bo Young Kim ),황선정 ( Sun Jung Hwang ),박병준 ( Byung Joon Park ),이은실 ( Eun Sil Lee ),한호섭 ( Ho Suap Han ),김용욱 ( Yong Wook Kim ),김태응 ( Tae Eung Kim ),노덕영 ( Duck Yeong Ro ),이안희 ( An Hi Lee ) 대한산부인과학회 2010 Obstetrics & Gynecology Science Vol.53 No.9
Basal cell carcinoma (BCC) is the most common human malignant neoplasm, accounting for 75% of all non-melanoma skin cancer. The incidence of BCC is strongly correlated with sun exposure as well as older age. Therefore, the vast majority of BCCs is observed in elderly patients on the sun-exposed skin of the head and neck with a frequency of more than 80%. BCC is very rare on sun-protected skin such as the perianal and genital regions and other etiologic factors must be considered in these cases. Although the pathogenesis of vulvar BCC is unclear, early diagnosis is very important. Because BCC in these areas sometimes seems innocuous, it is recommended that a biopsy of all suspect lesions be performed. We report a woman with BCC of the vulva treated with wide local resection and reviews the literatures on this subject.
국내 IT 요원의 이직의도 결정요인에 관한 실증 연구 : 리더십과 임파워먼트를 중심으로
이선로,김기영 한국정보사회진흥원 2006 정보화정책 Vol.13 No.4
국내∙외적으로 IT 요원들의 이직률증가는 세계적인 현상으로 나타나고 있다. 본 연구에서는 IT 요원의 개인적 특성을 고려한 관리자의 리더십이 이들의 심리적 동기수준과 태도에 변화를 줌으로 결국 이직의도를 낮추는데 기여할 것으로 보고 통합모형을 개발하였다. 연구결과, 관리자의 변혁적∙거래적 리더십의 병행지원이 IT 요원의 임파워먼트, 추가노력, 직무만족, 그리고 조직몰입을 증대시킴으로써 결국 이직의도를 낮추게 하는 중요한 변수로 작용하고 있었고, 거래적 리더십은 직무만족에 그리고 변혁적 리더십은 조직몰입에 상대적으로 좀 더 강한 영향을 미치고 있는 것으로 나타났다. 이러한 결과는 두 리더십의 병행지원이 IT 요원들의 임파워먼트와 추가노력, 직무만족을 증대시킴으로 조직에 대한 몰입을 유도할 수 있으며 궁극적으로 IT 요원의 이직의도를 낮출 수 있다고 해석할 수 있겠다. 결국, 본 연구에서는 IT 관리자의 리더십과 IT 요원의 임파워먼트는 선행연구에서 강조되어 왔던 직무특성과 경력지향성과 더불어 IT 요원의 이직의도와 유의한 인과관계가 있음을 보여주고 있다.
민영기,오선영,노태익,박상태,이대원,이삼열 東亞大學校 1996 東亞論叢 Vol.33 No.-
Total cross sections was measured for 6.45MeV∼8.96MeV (average 7.7MeV) neutron on ??, ??, ?? absorber using ?? fast neutron source. The 2" ø×2" NE-213 organic liquid scitillation detector was used as a spectrometer of neutrons and gamma-rays. The zero crossing time analysis method was introduced in order to obtain the pulse heigh spectrum of neutrons and n-γ pulse-shape spectrum was investigated. The ratio of neutron peak for a Vally was 1:20. The total cross section resulting from the experiment enabled us to suppose a optical model as a neutron model, obtain the radius of a nuclei.
5-FU 투여후 백서 가슴샘에서 일어나는 형태학적 및 생화학적 변화
손영탁,김선,정옥,한승로,김수일,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2
Thymus is a lymphoid organ forming T-cells from hematogenous stem cells. Apoptosis of thymocytes in the cortex of thymus is so rapid that cannot find easily with routine histological techniques. In this experiment, TUNEL immunohistochemistry and TEM were used to detect apoptotic changes after 5-fluorouracil treatment in the thymus of the rat. In addition, SDS-PAGE was carried to reveal protein changes along the apoptotic changes. The results were as follows ; 1. Thymocytes in the cortex were decreased markedly and many apoptotic cells were found in the cortex on DAT 3. 2. Relatively small-sized apoptotic bodies induced by 5-FU were detected on DAT 3 at the cortex, and clustered in partly. 3. On DAT 6, new germinal centers formed in the peripheral cortex, and many apoptotic bodies of various size and shapes were detected in the germinal center. 4. In SDS-PAGE, a protein with molecular weight of 123kDa was increased on DAT 6. According to the above results, it could be concluded that 5-FU acted directly on the thymocytes and induced apoptotic changes on DAT 3. But, on DAT 6, the period of recovery, new germinal centers were formed in the cortex, in which active B cell production to compensate the loss of thymocytes was noticed. To make new T-cells from B-cells and to eliminate unnecessary B-cells, vigorous apoptosis in the germinal centers should occur, and 123kDa proteins which considered as integrins should act as transmembrane signaling molecules in this process.
조영석,권기현,이준철,나소영,이효진,홍우정,이유선,김군순,송민호,김영건,노흥규 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2
Prediction of thrapeutic response to radioiodine in Graves' disease is poorly understood. Although thyrotropin binding inhibitor immunoglobulin(TBII) level is a strong index for relapse after antithyroid drug medication, conflicting results are reported regarding its prognostic significance in Graves' disease treated with RAI. This study is dengned to evaluate possible relationship between post-treatment hypothyroidism and TBII in Graves' disease treated with RAI. Fourty two patient with Graves' disease after radioiodine treatment were studied retrospectively. The subject were divided into hypothyroid group and euthyroid or hyperthyroid group. We evaluated the association of hypothyroidism and TBII with radioiodine treatment dose. The mean age of hypothyroid group was 48±11 years and euthyroid or hyperthyroid group was 47±12 years. There was no difference in two groups. And there was no significant difference in post- treatment TBII between two groups(49.9±28.5%, 29.9±14.3%, p-value >0.05). The treatment-dose had no influence on post-treatment thyroid state. Euthyroid or hyperthyroid group was done with 13.6±6.9mCi and hypothyroid group was 17.0±10.4mCi(p-value > 0.05). TBII had no prognostic significance on long-term hypothyrodism in Graves' disease treated with radioiodine. And, treatment-dose had no influence on post-treatment thyroid state.
李基百,盧承宇,崔英鮮 충주대 산업과학기술연구소 1999 産業科學論文集 Vol.7 No.2
Fault diagnostic system based on qualitative diagnosis model requires data pre-processor that transforms sensor data from control system to qualitative symbol. This paper addresses three practical problems, which should be dealt in the pre-processor. In order to handle transient response of process variables, m-CUSUM was developed as a new detection method. Especially, the pre-processor requires the method to calculate a key parameter, steady-state standard deviation. Also, this study suggests the method to decide steady-state after the change of process state and reset central values.