水稻의 登熟向上에 關한 硏究

諸商律,李寅杰,김랑춘,李準琸,張南日,洪鍾旭 慶北大學校 1974 論文集 Vol.18 No.-

This study was made to get the cultural information for increasing yield with recently improved variety, investigating the effects of different transplanting date and seed size, the number of plant per hill on the growth, and the yield and yield components in rice. The results obtained were summaried as follows: 1. In larger seed, the percentage of germination was higher and the early growth was more vigorous. However, there appeared no effects of seed size in the later growing period. 2. When the young plants sown on April 26 were transplanted on 5th, 15th, 25th of June and 5th of July with 10-days interval, the heading date was promoted in earlier transplanted plots. The days to heading, however, was shortend. 3. In the case of the earlier transplanting in Tongil variety, the maximum number of tillers was increased, the percentage of effective tillers was decreased, and the rate of ripened grains was slightly higher. The yield was the highest in the transplanted plot of June 25. The next came the transplanted plots of 25th, 5th of June and 5th of July. In the early transplanted plot of Palkweong variety, heading was also promoted. The days required for heading were also proportionly shortend, the number of the effective tillers was smaller and the percentage of ripened grains also decreased. The productivity was the highest in transplanted plot of June 25. 4. When the number of plants per hill was increased, the heading date was promoted, the number of panicles was high and the number of grains per panicles was decreased. In the early transplanting of Tongil variety, the yields was the highest in 4-plants plot. When transplanted late, it was the highest in 6-plant plot. In Palkweong variety, there was general tendency of increasing of yield as the number of plants per hill increased. 5. The dwarf disease of Tongil variety and the stripe disease of Palkweong variety occurred much in case of the lesser number of plants per hill and the earlier transplanting.

유기용제 취급근로자들의 요중대사물질과 말초임파구 자매염색분체교환 발현빈도에 관한 조사연구

김돈균,황인경,류철인,이수일,정갑열,이용환,이충렬,현원일,김석봉,전용덕 大韓産業醫學會 1990 대한직업환경의학회지 Vol.2 No.1

저자들은 유기용제 취급여성근로자 90명을 대상으로 1988년 7월부터 1989년 8월까지 말초혈액임파구에서의 자매염색분체교환의 발현빈도를 조사하고 이들의 업종, 근속연수, 요중마뇨산 농도등이 자매염색분체교환의 발현빈도에 미치는 영향을 조사하였으며 그 결과를 요약하면 다음과 같다. 1. 유기용제 취급근로자들의 말초혈액임파구에서의 자매염색분체교환의 발현빈도는 대조군에 비하여 유의하게 증가되었다. 2. 말초혈액임파구에서의 자매염색분체교환의 발현빈도가 가장 높은 업종은 프라스틱제품 제조업이었다. 3. 근속연수가 말초혈액임파구에서의 자매염색분체교환의 발현빈도에 미치는 영향은 현저하지 않았다. 4. 요중마뇨산농도와 말초혈액임파구에서의 자매염색분체교환의 발현빈도간에는 유의한 상관관계가 있었다. In order to know the possibility of utilizing the sister chromatid exchanges as an index which could evaluate the effect of organic solvents on the health in industrial workers, the authors studied the effects of the inductivity of sister chromatid exchanges in peripheral lymphocytes from 90 female workers expoxed to organic solvents and 20 non-exposed female workers. The results obtained were as follows : 1. The frequency of sister chromatid exchanges in peripheral lymphocytes from 90 female workers exposed to organic solvents was significantly increased in comparison with 20 control subject. 2. The frequency of sister chromatid exchanges was significantly increased in the workers who were employed in the manufacture of plastic materials than the other manufactures. 3. There were no significant differences in the frequency of sister chromatid exchanges by carriers of the exposed workers.

형광직접접합법에 의한 인간정자의 연령별 염색체이상에 관한 연구

이숙환(Sook Hwan Lee),윤태기(Tae Ki Yoon),차광열(Kwang Yul Cha),곽인평(In Pyung Kwak),이재호(Jae Ho Lee),엄기봉(Ki Boong Oum),손지은(Jie Ohn Shon),고정재(Jung Jae Ko) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.2

N/A Determmation of the chomosomal constitution of human spermatozoa has been camed out though the human-hamster interspecific in vitro fertilization(IVF) system. In recent years, the introduction of fluorescence in-situ hybridization(FISH) technique has provided an alternative approach to evaluate the cbmmosomal constitution of human spermatozoa. The nuclei of mature spermatozoa are highly condensed with interpmtamine disulphide bridges, therefore the success of FISH on interphase human spermatozoa relies on partial decondensation of the sperm chromatin. In early studies, dithioothreitol(DTT) has been known as an efficient decondensation agent. Since then, several different decondensation methods using D1T have been establisdhed, and in terms of decondensation, we were tried to fix the optimal decondensation protocol using DlT. In our study, the optimal concentration and treatment time were 1-mM and 30 min, respectively. We examined chromosome complements of human sperm to investigate the effect of paternal age on the hequency of nondisjunction in human sperm. We investgated sperm karyotypes ftom two diffaent age groups)28+-0.5, 46+-6), A minimum of 1000 spermatozoa for one patient were analyzed. The mean frequencies of YY, XX, XY, 21-disamy spermatozoa ware 0.04%, 0.45%, 0.40%, 0.45% respectively in young age group and 1.06%, 0.62%, 1.06%, 0.76% in old ages. The mean frequency of disomy spermatozoa was higher in old age poup compare with those of young age group.

분자선 에피탁시법으로 성장된 Al0.25Ga0.75As / In0.15Ga0.85As / GaAs 슈우도형 고 전자 이동도 트랜지스터 구조의 광학적 특성

이동율(Dong-Yul Lee),이철욱(Chul-Wook Lee),김기홍(Ki-Hong Kim),김종수(Jong-Su Kim),김동렬(Dong-Lyeul Kim),배인호(In-Ho Bae),전헌무(Hunmoo Jeon),김인수(In-Soo Kim) 한국진공학회(ASCT) 2000 Applied Science and Convergence Technology Vol.9 No.2

Photoluminescence(PL)와 photoreflectance(PR}를 이용하여 Al_(0.25)Ga_(0.75)As/In_(0.15)Ga_(0.85)As/GaAs 슈우도형 고 전자 이동도 트랜지스터 구조에 대한 특성을 조사 하였다. 온도 10 K의 PL 측정에서 InGaAs 양자우물에 의한 e2-h1 및 e2-h1 전이 피크가 각각 1.322 및 1.397 eV에서 관측되었다. 온도 의존성으로부터 첫번째 가전자 띠와 두번째 가전자 띠의 에너지 차이는 약 23 meV로 나타났다. 또한 300 K에서의 PR 측정으로 e2-h2 및 e2-h1 전이에 의한 피크를 관측하였고, 두번째 전도 띠의 에너지 준위에 의한 피크가 띠 채움으로 인해 첫번째 전도 띠의 에너지 준위에 의한 피크보다 상대적으로 우세하였다. 반면에 PL 측정에서는 전자 가리개 효과 때문에 첫번째 전도 띠에 의한 피크가 우세하였다. We have analyzed characteristics for the structure of Al_(0.25)Ga_(0.75)As / In_(0.15)Ga_(0.85)As/GaAs pseudo-morphic high electron mobility transistor (PHEMT) by photoluminescence (PL) and photoreflectance (PR) measurements. By the PL measurement at 10 K, we observed e1-h1 transition peak at 1.322 eV and e2-h1 transition peak at 1.397 eV in the InGaAs quantum well. We calculated value of 23 meV, the difference between the first energy level and the second energy level of a valence band by dependence of temperatures. Also, (e2-h2) transition signal was observed at 300 K by PR measurement. From the PR measurement, we recognized that the transition was dominated the second energy level of conduction band than the first energy level of conduction band due to band filling. The other hand, PL signal of the first energy level of conduction band was dominated because of the electron screening effect.

Depletion of adipocyte Becn1 leads to lipodystrophy and metabolic dysregulation

Yaechan Song,Young Jin,Yul Ji,Sung Sik Choe,Yong Geun Jeon,Heeju Na,Tae Wook Nam,Hye Jeong Kim,Hahn Nahmgoong,Sung Min Kim,Jae-woo Kim,Ki Taek Nam,Je Kyung Seong,Daehee Hwang,Chan Bae Park,In Hye Lee 한국실험동물학회 2021 한국실험동물학회 학술발표대회 논문집 Vol.2021 No.7

Macroautophagy is a catabolic process that delivers damaged and unnecessary cytosolic contents to lysosomes for removal of defective subcellular organelles and proteins. Becn1 is a key regulator of autophagy, forming a complex with class III phosphatidylinositol 3-kinase (PI3K-III) to initiate autophagosome formation. Although Becn1 has been implicated in numerous diseases such as cancer, aging, and neurodegenerative disease, its function in mature adipocytes remains elusive. In this study, we implemented Adipoq-Cre to generate adipocyte-specific Becn1 KO (BaKO) mice to identify the function of autophagy in adipose tissue homeostasis. BaKO mice naturally developed severe lipodystrophy and metabolic dysregulation, which were exacerbated upon high dietary fat intake. These mice also acquired adipose tissue inflammation, hepatic steatosis, and insulin resistance which advanced to early mortality. Immortalized stromal vascular cells (imSVCs) were established in-vitro to conditionally knock-out Becn1 upon tamoxifen treatment. Ablation of Becn1 in adipocytes led to programmed cell death in a cell-autonomous manner, accompanied by elevated endoplasmic reticulum (ER) stress gene expression. Furthermore, we observed that Becn1 depletion sensitized mature adipocytes to ER stress through activation of protein kinase R-like ER kinase (PERK) – eukaryotic initiation factor 2α (eiF2α) axis. This led to excessive unfolded protein response (UPR) and accelerated cell death through notable induction of C/EBP homologous protein (CHOP) and Bax expression. Taken together, these data suggest that adipocyte-Becn1 would serve as a crucial player for adipocyte survival and adipose tissue homeostasis.

영지(Ganoderma lucidum)균사체의 액체배양에 의한 세포외 수용성 다당류의 분획 및 항암활성

이신영,강태수,문순옥,류인덕,이명열 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.4

영지 균사체의 액체배양에 의하여 생산된 세포외 다당 시료를 분획하였고, 이들 각 분획에 대한 항암 활성을 균사체 유래 다당 분획들과 비교하면서 조사하였다. 배양여액으로부터 세포외 수용성 다당(BWS)을 얻었고, 이를 순차적으로 이온교환 및 겔 크로마토그라피 하여 BWS를 포함한 세포의 수용성 다당 분획, 총 5종을 얻었으며, 균사체 유래의 수용성 다당(MWS)에서도 세포외 다당과 동일한 방법으로 분획하여 총 5종의 분획을 얻어 대조구로 시용하였다. 세포외 다당 시료들의 항보체 활성(ITCH_50, %)은 15~30% 정도로 15~70%인 균사체 유래 다당 분획들의 값보다는 낮았으나, 이들 세포외 다당 분획들의 값보다는 낮았으나, 이들 세포외 다당 분획들중, BWS-DA와 BWS-DA-GI는 1000 ㎍/ml의 시료 농도에서 30% 정도의 매우 높은 활성을 나타내었다. MTT assay에서는 mouse leukemia L1210에 대하여 BWS-DN 및 MWS가 600㎍/ml의 농도에서 각각 86 및 89%의 높은 저해율을 나타내었으며, BWS-DA 및 MWS-DN의 경우는 3㎍/ml의 매우 낮은 농도에서도 32~35%의 저해율을 보였다. 또 human cell line인 COLO-205에 대해서는 BWS와 BWS-DA 및 MWS-DA가, 그리고 HL-60에 대해서는 BWS-DA와 BWS-DN 및 MWS-DN이 각각 300㎍/ml의 시료 농도에서 약 50%(IC_50)의 높은 저해능을 나타내었다. Exo-polysaccharide (BWS) obtained from submerged cultivation of Ganoderma lucidum mycelium was fractionated. Antitumor activity of their fractions was investigated in comparison with the mycelial polysaccharide fractions. Eight kinds (BWS-DN, BWS-DA, BWS-DN-GI, BWS-DA-GI, MWS-DN, MWS-DA, MWS-DN-GI and MWS-DA-GI) of polysaccharide fractions were obtained by DEAE-cellulose ion exchange chromatography and Sepharose CL-4B gel chromatography from BWS and MWS, which were isolated from culture fluid and mycelial cell, respectively. The anticomplementary activities (ITCH_50, %) of the exo-polysaccharide fractions showing 15% to 30% were lower than those of mycelial polysaccharide fractions showing 15% to 70%. The acidic fractions of BWS-DA and BWS-DA-GI fractionated from BWS, showed the highest activity of 30%. In the MTT assay, BWS-DN and MWS against mouse leukenia L1210 exhibited high inhibition ratio of 86 and 89%, respectively at the concentration of 600 ㎍/ml. High inhibition ratio of 50% (IC_50) was achieved for BWS, BWS-DA and MWS-DA fractions against human colon adenocarcinoma COLO-205 and for BWS-DN, and MWS-DN fractions against human leukemia HL-60 at the concentration of 300 ㎍/ml among the six polysaccharide fractions, respectively.

철을 오염시킨 n-GaAs의Photoreflectance에 관한 연구

유재인,문영희,이동울,이정열,배인호,장광수 嶺南大學校 基礎科學硏究所 1998 基礎科學硏究 Vol.18 No.-

We investigated the variation of PR signals for n-GaAs surface treated with Fe as annealing method. The samples were annealed by isochronal(200∼600 ℃, 10 min) and isothermal(300 ℃, 10 ∼60 min) method. In PR signals measured from isochronal annealed samples, the rate of intensity decreasing for n-GaAs was 49%, and that for n-GaAs surface treated with Fe was 66%. We assumed that the large amount of decreasing intensity for Fe contaminated sample caused by decreasing carrier density due to increasing of ?? neutral acceptor at higher annealing temperature. In PR signals measured from isothermal annealed samples, the signals for annealed n-GaAs decreased with increasing annealing time, and the signals for n-GaAs surface treated with Fe continuously increased with increasing annealing time. It can be assumed that the increasing of PR intensity for Fe contaminated samples as annealing time caused by the diffusion of Fe atoms from the surface.

Effects of In-Situ Annealed Buffer Layers in Oxygen Plasma on Properties of ZnO Epitaxial Layers Grown by Plasma-Assisted Molecular Beam Epitaxy

Min Su Kim,Do Yeob Kim,Ghun Sik Kim,Hyun Young Choi,Min Young Cho,Su Min Jeon,Kwang Gug Yim,Ji Hoon Kim,Dong-Yul Lee,Joo In Lee,Sung Dong Park,Eundo Kim,Myong Hyo Jung,Do-Weon Hwang,Jae-Young Leem 한국진공학회 2009 한국진공학회 학술발표회초록집 Vol.37 No.-

'1998 한국인 우울증 선별의 날' 참가자들의 사회인구통계학적 특성과 우울증 선별검사 결과

한상익,이성필,고효진,박원명,장계호,유태열,전태연,채정호,방승규,김광수,최보문,이정태,백인호 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

연구목적 : 1998년 정신건강의 날 기념 한국인 우울증 선별의 날 행사에 자발적으로 참여한 참가자들의 사회인구 통계학적 특성을 분석하고 우울증 선별검사 결과를 평가하기 위하여 본 연구를 시행하였다. 방 법 : 8개 병원에서 얻어진 619명의 자료를 사용하여 선별검사로 밝혀진 우울증의 유병율과 사회인구통계학적 특성 및 응답자의 정신과적 치료를 포함한 과거력 등을 조사하였다. 결 과 : 우울증 척도 점수는 응답자 전체 평균 57.5±13.8로 경도의 우울 증상이 있는 것에 해당되었다. 전체 응답자의 69.5%(430명)가 최소한 경도 이상의 우울 증상을, 43.1%(267명)가 중등도 이상의 우울 증상을, 18.4%(114명)가 고도의 우울 증상을 보였다. 고도의 우울 증상이 있는 응답자의 56.8%와 중등도의 우울 증상이 있는 응답자의 63.9%가 정신과 치료를 받은 적이 전혀 없었다. 나이가 29세 이하인 것과 전임근무 중인 직업상태는 각각 나이가 60세 이상인 것과 직업이 없는 것에 비교하여 우울증으로부터 보호하는 인자임을 시사하였다. 결 론 : '1998 한국인 우울증 선별의 날' 행사를 통하여 많은 우울증 환자들을 선별해낼 수 있었고, 이들의 우울 증상은 몇몇 사회인구통계학적 특성과 유의한 관계가 있음을 확인하였다. 우울증 선별의 날 행사를 통한 우울증에 대한 교육과 우울증 선별검사는 치료받지 못하고 있는 우울증 환자 및 기존의 치료 중인 환자 모두에게 유용한 프로그램임을 알 수 있었다. Objectives : This study was performed to analyze the sociodemographic characteristics of participants in '1998 Korean Depression Screening Day' and to evaluate the results of the screening test. Methods : By using the survey results of 619 volunteers from 8 hospitals, the authors examined the prevalence of depression detected at the screening test and sociodemographic characteristics and the psychiatric treatment history of respondents. The assessment measure was the Zung Self-Rating Depression Scale. Results : The mean depression score of all participants was 57.5±13.8 and it came under mild depression. Of all participants, 69.5%(N=430) had at least mild depressive symptoms, 43.1%(N=267) had at least moderate symptoms, and 18.4%(N=114) had severe symptoms. Never have 56.8% of respondents in the severely depressed range and 63.9% of those in the moderately depressed range had psychiatric treatment. The results suggest that the age group of 29-year-old or younger(relative to 60-year-old or older group) and full-time employment status(relative to unemployment) are protective factors of depression. Conclusions : By '1998 Korean Depression Screening Day', many depressed patients were detected and their depressive symptoms had statistically significant relationships with some sociodemographic characteristics. The results suggest that the education and screening test programs for depressive illness facilitated by Depression Screening Day are useful to the patients regardless of being under current treatment or not.

일 지역 농업인의 근력강화운동이 정신사회 및 신체적 건강수준에 미치는 영향

정민예,양노열,유인규,고상백,이경숙,김경란,김효철 大韓産業醫學會 2008 대한직업환경의학회지 Vol.20 No.4

목적 농업인을 대상으로 근골격계질환의 예방과 관리를 위한 근력강화운동을 실시하여 심리상태와 신체능력에 미치는 효과를 밝힘으로써 농작업과 관련된 향후 치료프로그램의 기초자료를 제공하고자 하였다 방법 규칙적인 운동프로그램의 참여 경험이 없는 농작업 종사자 28명을 대상으로 8주간 주 3회 근력강화운동을 실시하여 4주 이상 규칙적으로 참여한 대상자의 정신사회적 수준(자아존중감 사회심리적 스트레스) 신체적 수준(장악력 민첩성 동 정적 균형능력 근지구력) 요통 수준의 변화를 측정하였다 결과 근력강화운동에 참여한 대상자들의 자아존중감은 운동전에 비하여 유의하게 향상되었고 사회 심리적 스트레스는 유의하게 감소하였다 장악력 민첩성 동 정적균형능력은 운동 후 모두 유의하게 향상되었으며 요통 수준 또한 유의하게 감소하였다 결론 농업인에게 근력강화운동의 적용은 심리적인 안정을 주고 신체능력을 향상시켜 근골격계질환을 예방하고 관리하는데 적합한 치료프로그램으로 사용될 수 있으며 요통 수준을 감소시키는데 유용한 프로그램이었다. Objectives To evaluate both the psychosocial and physical effects of muscle strengthening exercise on farmers and in so doing evaluate their effect on musculoskeletal disorders in farmers. Methods 28 subjects participated in our muscle strengthening exercise program. Mean age of subjects was 63±13 years. The exercise program was performed 3 times a week during the 8 week studys period Before and after training various measurements were made self esteem scale (SES), psychosocial well being index short form (PWI SF), static and dynamic balance ability grip strength arm curl, time up and go (TUG), functional reach, and oswestry disability index. Results The muscle strengthening exercise program increased the self esteem grip strength and static and dynamic balance of subjects, while psychosocial stress and low back pain levels were decreased significantly (P<0.05) Conclusions The muscle strengthening exercise improved psychosocial and physical status of test subjects. Thus exercise may be an effective strategy for enhancing the psychosocial and physical health of farmers.