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An Jin,Xuelian Xiang,Yun-Yun Zhu,Heng-Yi Yu,Hui-Fang Pi,Peng Zhang,Han-Li Ruan 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.3
Three new alkaloids, 2a-hydroxy-6-O-n-butyloduline,O-n-butyllycorenine, (-)-N-(chloromethyl)lycoramine(1–3), and a new phenolic compound, ((7S)-7-(4-hydroxyphenyl)-7-hydroxypropyl)-20-methylbenzene-30,60-diol (14), along with ten known alkaloids (4–13), wereisolated from the bulbs of Lycoris aurea collected fromHuaihua County of Hunan Province, China. Their structureswere elucidated by spectroscopic methods includingHRESIMS, UV, IR, and NMR. All the isolated compoundswere tested for their neuroprotective effects against CoCl2and H2O2-induced SH-SY5Y cell death. Compounds 1–7and 10 exhibited significant neuroprotective effects againstCoCl2-induced SH-SY5Y cell injury, while compounds1–5, 7, 10 and 12 showed obvious neuroprotective effectsagainst H2O2-induced SH-SY5Y cell death.
김유진,박미경,박이랑,이보람,이혜림,전선미,양난영,김수지,이자형 이화여자대학교 간호과학대학 2004 이화간호학회지 Vol.- No.38
The results of this Study are as follows:33.6% of all participants have insomnia; 22.5% of those who have insomnia are DIS(difficulty in initiating sleep), 17.3% are DMS(difficulty returning to sleep once awakened) and 7.0% awakened too early. 3 4.8% experience sleepiness during daytime. Type 1, experiencing insomnia and sleepi ness during daytime together, is 12.0%, Type 2, with insomnia only, is 21.6%, Type 3, with sleepiness during daytime only, is 22.8% and 43.5% experience no sleeping disturbances. After studying only those with 3 types of sleeping disturbances, it is found that the most common cause of such disturbance is stress 88.4%, anxiety 56.0%, no apparent reason 33.8%, anxiety/fear/terror 29.3%, hurry 23.6%, alcohol/caffeine 16.9%, bedroom tem perature 11.1%, urination during nighttime and persons living together 10.7%, noise from inside 8.9%, illumination 8.0%, and pain/itch 5.8%. The one group revealed significant differences in residential environment(p=0.003). Sex, age, education level, medicine, monthly earning revealed no meaningful differences. Of sleeping behavior, mean duration of sleep latency(p=0.000), whether or not feeling freshness(p=0.000), whether taking enough sleep(p=0.029), whether taking regular sleep(p=0.005) showed significant differences depending on whether or not having insomnia, and mean duration of sleep time, time to sleep, time of rising, whether taking naps did not reveal significant differences. Of sleep behavior, time to sleep(p=0.000), whether taking naps(p=0.000), indicated significant differences. Of sleeping behavior, mean duration of sleep latency(p=0.000), whether or not feeling freshness(p=0.000), and whether taking enough sleep(p=0.000), time of going to bed (p=0.002), whether or not taking nap(p=0.000), whether or not taking regular sleep(p=0.010) indicated significant differences among the sleeping disturbance types.
서충진,강유원,김이수 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1
Where is the Oriental martial arts going in these days? Can it be separated with sports or physical education to get its own region? To get a solution from these questions, there are three parts of studies of the possible trends on Korean martial arts such as the actual conditions on educating coach of martial arts, the research about thesis of martial arts, and the actual conditions of related journals. For the conclusion, the following five solutions could be shown. At first, there should be a general modification on processing of educating the martial arts coach. 1. Expanding the items of martial arts can raise the level of coach's educating quality based on the curriculum, the contents, and the variety programs. 2. Martial arts sports, ordinary martial arts, and traditional martial arts must be unifiable and simple to develope its problems. 3. the importance of traditional martial arts and the qualified test of its coach must have a mutual preservation and maintenance through being related with each other between martial arts' each items. Second, it's necessary to train the martial arts with required elements of the recognition, the theory, the existence and the philosophy. Third, it's necessary to take shape of pyramidical structure through the long term policy of training martial arts. Forth, variety events of martial arts should be held regularly from the government. At last, it's necessary to expand the martial arts region and make variety activities from related academies or institutes.
뇌졸중 위험인자를 가진 어지럼 환자에서의 확산강조 자기공명영상
강형구,윤유상,이진희,박인철,이경룡,정상원,구홍두,김승호 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4
Background: The management of vertiginous patients is a great challenge to emergency physicians. We evaluated the diagnostic value of a diffusion-weighted image(DWI) in differentiating central vertigo from the peripheral vertigo in patients who presented no neurological symptoms other than risk factors for stroke. Methods: From March 2000 to February 2001, we retrospectively analyzed the cases of 68 patients who visited the emergency department with symptoms of isolated vertigo and who had risk factors for stroke. DWIs, computed tomograms(CT), and medical records were reviewed, and the final diagnose, the DWIs and the CT readings, the risk factors for stroke, and the time it took waiting for a DWI or CT scan were analyzed. Results: Of the 68 patients, 21(30.8%) had central vertigo: 15 vertebrobasilar transient ischemic attacks(VB-TIA), 4 brain stem infarctions, 1 cerebellar infarction, and 1 cerebellopeduncular infarction. The DWI showed a 28.6% sensitivity, a 97.9% specificity, and an 85.7% positive predictive value in diagnosing central vertigo. It also had a 100% sensitivity in detecting infarctions. Conclusion: A DWI had a comparable sensitivity to MRI in detecting central vertigo and small, but potentially, lethal infarctions in our patient population. We recommend clinical application of DWI in the emergency department evaluation of isolated vertigo patients with risk factors for stroke.
이순이 루갈다 옥중편지 현전 필사본의 자료적 가치와 해독의 문제
이유진(Yi Yu-jin) 한국교회사연구소 2012 敎會史硏究 Vol.0 No.40
The goal of this paper is to examine the reliability of Kim Jong-ryun’s copies of the letters from prison written by Yi Sun-i, and to solve the interpretative problems which are found in annotations to Kim Jong-ryun’s copies as well as in translations of Kim Jong-ryun’s copies which have been published so far. The annotation by Kim Jung-gu(1965), the annotation by the Research foundation of Korean Church History(1982), the translation by Yang Hee-chan and Byun Joo-seung(2002), and the translation with annotation by Lee Tae-yeong and Yoo jong-kuk(2011) have contributed to an intimate interpretation of Kim Jong-ryun’s copies. However, considerable parts of these copies still remain unperceivable. Therefore, it is necessary to discuss how we should read and understand those parts. But, there is more urgent issue. It is well known that some contents of Kim Jong-ryun’s copies are not found in Mgr Daveluy’s French translation, and that some contents of Mgr Daveluy’s French translation are not found in Kim Jong-ryun’s copies. For this reason, some researchers suspected that there should be significant differences between Kim Jong-ryun’s copies and the copies which Mgr Daveluy used for French translation. If it were true, it would be dangerous to take Kim Jong-ryun’s copies for basis of research as most researchers have done so far. Therefore, it is very important to go over the differences between Kim Jong-ryun’s copies and Mgr Daveluy’s French translation, and to define where the differences come from.
Yi-Ting Yang,Yu-Shin Nai,Se Jin Lee,Sihyeon Kim,Jae Su Kim 한국응용곤충학회 2016 한국응용곤충학회 학술대회논문집 Vol.2016 No.04
A novel insect-infecting positive sense single-stranded RNA virus, Riptortus pedestris virus-1 (RiPV-1), was found in the Riptortus pedestris transcriptome data by de novo assembly and further confirmed by RACE method. The genome of RiPV-1 consists of 10,554 nucleotides (nt) excluding the poly(A) tail and contains a single large open reading frame (ORF) of 10,371 nt encoding a 3,456 aa polyprotein and flanked by 71 and 112 nt 5' and 3' noncoding regions, respectively. RiPV-1 genome contains the consensus genome organization of picorna-like RNA helicase, cysteine protease, and RNA-dependent RNA polymerase (RdRp) array in that order from the 5' to the 3' end. From the phylogenetic analysis, RiPV-1 was clustered with unassigned insect RNA viruses, APV and KFV, which suggests that these three insect picorna-like viruses might constitute a novel group of insect-infecting RNA viruses. Tissue tropism analysis revealed that RiPV-1 was relatively abundant in the thorax, abdomen, midgut and fat body. Interestingly, RiPV-1 replication was enhanced by Beauveria bassiana JEF-007 infection that was quantified using qRT-PCR. This study identified a novel insect-infecting virus and provided further insight into the relationship between virus, fungus and host.
Jin, Cho-Yi,Han, Song-Yi,Kwon, Kisang,Yun, Eun Young,Kang, Seok Woo,Goo, Tae Won,Kim, Seung-Whan,Yu, Kweon,Kwon, O-Yu Walter de Gruyter GmbH 2010 Zeitschrift fur Naturforschung. Section C Vol.65 No.1
<P>Using silkworm Bombyx mori Bm5 cells, we established a stable cell line expressing the human granulocyte macrophage colony-stimulating factor (hGM-CSF), which gets its name from the Bm5-hGM-CSF cell in which the glycoprotein of the hGM-CSF is secreted in the cell culture supernatant (CCS). It was demonstrated that secreted hGM-CSF had in vivo biological activity and the white blood cell (WBC) value increased two times that of the control. We expect to produce useful human recombinant glycoproteins from silkworm cultured cells for a low price and a large quantity</P>