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      • KCI등재

        신규간호사와 프리셉터가 인지하는 프리셉터의 교수효율성 비교

        김지양,김영선,김춘실,박현숙,신미영,윤연숙,조유숙,박미미,유문숙 한국간호과학회 간호행정학회 2009 간호행정학회지 Vol.15 No.2

        Objective: The purpose of this study was to compare preceptors and new graduate nurses on their perception of preceptor teaching effectiveness. Methods: The participants were 90 new nurses and 90 preceptors who worked in A medical center. The data were collected from July 1 to September 30, 2008. A cross-sectional descriptive survey was done using a structured questionnaire. Results: New nurses' perception (4.07±.44) of the preceptor teaching effectiveness was significantly higher than perception of the preceptors (3.57±.37). Fifty five percent of new graduate nurses reported a lack of coherence in the preceptor's practice guidelines. For 5 causal factors classified on the teaching effectiveness, the factor of 'Professional knowledge and ability' showed the highest score, but 'Interpersonal and communication skill' got lowest score for both group. Preceptors responded that they did not have enough time to teach well because of their heavy workloads. Conclusions: These results suggest that the preceptors need appropriate compensation and education opportunities, and new graduate nurses need consistent education by the teaching professionals. Therefore, it is important to give preceptors full charge of the preceptorship. Also, it will be necessary to develop education programs to enhance interpersonal and communication skill for preceptors and new nurses.

      • 간호대학생의 전문직관에 관한 연구

        유문숙 中央醫學社 1997 中央醫學 Vol.62 No.8

        The purpose of this study was to examine the attitude of nursing students toward nursing and views on nursing profession. The views of nursing profession is essential for the development of nursing and it is built up during the undergraduate period in nursing. The subjects of the survey were 195 nursing students from 2 junior nursing colleges. The data were 7btained from March 24 to April 4, 1997 through a self-reported questionnaire. The attitude of nursing students toward nursing was measured in 3 parts, aptitude, interest, and satisfaction by using the instrument developed by the researcher, and nursing profession was measured by Fingerhut’s professional attitude scale. Analysis of the data was done by using percentage, ANOVA, and Pearson correlation coefficient. The results were as follows ; 1. 56.9 % of the subjects were reported to have positive aptitude for nursing. 50.3 of them were interested in nursing. And 60.5 % were satisfied with nursing. 2. There views on profession were shown higher(mean=86, theoretically minimum 25 maximum 100). 3. The relationship between professionalism and attitude was found to be statistically significant ; aptitude(r=.147, p<.005), interest(r=.277, p<.000), satisfaction(r=.154, p<.005). As the results, it is necessary to make a good educational program for nursing students which can improve their attitude toward nursing and nursing profession.

      • KCI등재

        병원 간호사의 질 관리 및 의료기관평가제도에 대한 인식과 간호업무성과와의 관계

        유문숙,정명숙 대한간호학회 간호행정학회 2008 간호행정학회지 Vol.14 No.3

        Purpose: The objective of this study was to identify relationships among the perception of quality assurance and national hospital evaluation program and nursing performance of hospital nurses. Method: The participants were 401 nurses who worked at the A medical center. The data were collected from 25 April to 9 May. 2008. The cross-sectional descriptive survey was done using a structured questionnaire. Result: The perception of the quality assurance correlated significantly with nursing performance. Also, the perception of national hospital program correlated significantly with nursing performance. However, the scores of perception of quality assurance & national evaluation program of hospital nurses is relatively low. Conclusions: These results means positive perception of quality assurance of nurses can produce good nursing performance, It suggests that nurses need more education and training for quality assurance. And the incentives will be needed to enhance the perception of quality assurance. Moreover, the detailed nursing performance indicators should be developed to measure the quality of nursing performance properly.

      • KCI등재후보
      • 재고자산관리에 대한 간호사의 업무인지도와 만족도

        방영숙,류규수,김문주 경산대학교 보건복지연구소 2000 保健福祉硏究 Vol.5 No.-

        A study on satisfaction of nurses for inventory assets management of medical supplies The purpose of this study is to suggest an dfficient method of inventory assets management of medical supplies. This study used the data of nurses who are working at national hospitals, university hospitals, medical corporations, and private hospitals. The data were used to get the understandings and satisfactions of the nurses about inventory assets management of medical supplies. The results are as follows ; 1. Understandings(p<0.001) and satisfactions(p<0.05) of the nurses about their works grow over ages. There was a difference between a big city and a smaller one and there were also differences in each position of the nurses(p<0.001). According to a multiple comparisons test, the higher their position, the higher understandings and satisfaction of their works. In a case of the office in a hospital, the satisfaction of hardworking nurses in an operation room or emergency room was low(p<0.05). In a case of their working years, there was some difference in understandings and satisfactions by the type of a hospital is a private hospital, a university hospital, a medical corporation, and a national hospital, although not having a statistic significance. In the scale of a hospital, understandings and satisfactions were over 500, 3001-499, below 300 rooms, orderly, but this result was not significant, too. 2. The status of inventory assets management of medical supplies was 301-499, over 500, below 300, orderly, and the order by the type of a hospital was a private hospital, a medical corporation, a national hospital, a university hospital without the statistic significance. 3. Satisfactions had a strong positive correlation with understandings like satisfactions and inventory assets management of medical supplies. As well, the correlation coefficient of understandings and inventory assets management of medical supplies was positive as 0.525. and all of them were significant statistically(p<0.01). 4. Both the status of inventory assets management of medical supplies and understanding were significant, and this result show that each of inventory assets management of medical supplies and understanding had an effect on satisfactions. Key words : Satisfaction of nurses, Inventory assets management of medical supplies.

      • KCI등재

        인터넷 중독 성향을 보이는 청소년들에서의 기질성격 특성

        이문수,홍성도,정유숙 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.1

        Objectives : Recent studies have focused on characteristics of adolescents who use internet addictively. Due to many ambi-guides in the definitions of internet addiction, it is hard to find a tool for diagnosing internet addiction. In this study, we attempt to identify the temperamental characteristics of adolescents who have addictive internet using patterns by administering a newly developed internet addiction scale based on a psychometric technique and temperament and character inventory (TCI) based on Cloninger's psychobiological model. Methods : Participants were 566 high school students. 478 students were recruited from high schools, and 88 were selected from internet cafes. We applied the internet addiction scale and TCI. All the students were divided into 3 groups (high risk user group, Potential risk user group and normal user group) according to the results of the internet addiction scale. TCI scores were compared and analyzed according to the participants' characteristics. Results : There were significant differences in the distribution of internet user group according to gender. Boys had higher percentage of high risk and potential risk users than girls. When each TCI score was compared according to gender, girls showed significantly higher harm avoidance, reward dependence, cooperativeness scale scores and lower persistence, self-transcendence scale scores than boys. TCI scores were compared among the internet addiction risk user groups. Risky internet users showed lower scores in reward dependence, self-directness and cooperativeness dimensions than normal internet users. Conclusion : There was a gender difference in internet addiction hsk in this study. These results suggest that adolescents who use internet addictively also have higher tendency of problematic social and interpersonal relationship. These tendencies need to be considered as one of the important aspects of internet addiction. This study shows that assessment of temperament and character in adolescents who have problems related to the internet may be needed for understanding their addiction behaviors and underlying psychopathologies.

      • Purge & Trap-GC를 이용한 의약품 필름코팅 정제 중 잔류용제에 관한 연구

        장준식,이명자,소유섭,문춘선,이주헌,박희라,김진숙,강경모,이선옥,방성연,유미자,유문균,금오성,이병욱 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

        의약품은 약물을 생체에 적풋하기 위하여 유효성분의 효과가 언제나 일정하게 확보되고 사응에 편리하도록 만들어지는 것이므로 유효썽분 이외에 약효에 영향을 주지 않는 성분이 첨가되는 경운가 많다. 이 때 사용되는 용매들은 제피의 광택 및 건쪼시간의 단축 등을 위하여 휘발점이 낮을 용매들이 주로 사용되어진다. 본 연구는 의약품 필름코팅정제 중 잔류용매 4종(chlorofonr benzen, trichloro ethylen, 1,4-dioxane)에 대한 변형된 pirge & trap-GC 장치를 이용한 동시분석방법을 개발하였으며, 각 표준품의 RSD 값은 chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69% and 1,4-dioxane 3.41%였다. 또한 시중 유통중인 의약품 50종에 대하여 잔류웅매 양을 측정하였으며, 검출되는 잔류용매는 한 건도 없었다. This study nras carried out to develope the analytical method for the mixture of chlorefonn, benzen, trichloroethylen and 1,4-dioxane simultaneously and determine the remainingorgauic solvents in coating tablets by Purge & Trap-GC. The results were as follouFs ; 1. Chloroform, benzen, trio:tloroethylen and 1,4-dioxane separated by tenax #5 trap by HP-624GC column by terrlperature programming. The peaks were separated completely at retentiontime of 6.88min for chloroform, 8.21min for benzen, 10.38miu for trichloroethylen and 11.95minfor 1,4-dioxane. 2. Standard RSD were individually chloroform 3.03%, benzen 3.17%, trichloroethylen 3.69%and 1,4-diorane 3.41%. 3. 60 samples were not detrcted chloroform, benzen, trichloroethylen and 1,4-dioxane.

      • Cationic Liposome-Mediated p53 Gene Therapy in Liver Cancers: Result of Basic and Clinical Study

        Moon,Young Ho,Kim,Byung Koo,Shim,Hyung Jin,Uhm,Tae Han,Cha,Sung Jae,Moon,Chul So,Moon,Woo-Chul,Kwak,Byung Kook,Gi,Young Jin,Lim,Hyun Mook,Yoo,Nam Sook,Lee,Chang Joon 가톨릭중앙의료원 가톨릭암센터 1998 암심포지움 Vol.- No.2

        p53 is a prototype tumor suppressor gene, which plays key roles in regulation of cell cycle progression, apoptosis, DNA repair and maintenance of genomic stability. Experimental stydy study on p53 gene therapy for cancer have been widely tried and Success of adenovirus or retrovirus-mediated p53 gene therapy have been reported in patients with lung cancer and cancer of the head and neck. However, viral vector-mediated gene therapy may have demerits to be widely applied in human cancers. We herein have designed a cationic liposome-mediated p53 gene therapy and have studied its antitumor efficacy and safety in vitro, in vivo and in human patients with advanced liver cancers. We constructed and prepared a complex of plamid vector carrying cDNA of human wild type(WT) p53, cationic liposome (HECH : DOPE) and cationic polymer (polylysine) in sterile and endotoxin-free condition depending on the guideline of FDA and used this complex for in vitro and in vivo transfer oi WT p53 gene. In vitro administration of p53 gene to a variety of human cancer cells with point mutation or deletion of p53 in DNA dose of 1㎍ per ?? cells induced high level expression of WT p53 and p21/WAF1 as demonstrated by RT-PCR-Southern blot and Western blot, apoptosis as demonstrated by DNA electrophoresis, and significant decrease of viable cell numbers by 70.4 to 98.5%, whereas, administration of p53 gene in same condition to human cancer cells with WT p53 didn't induce either apoptosis or significant decrease of viable cell numbers. In vivo antitumor efficacy of p53 gene transfer was initially analyzed in sc,ip, subrenal capsular and intrahepatic xenograft model of human cancers with deletion of p53. Local, ip, or iv administration of p53 gene in DNA dose of 100㎍ daily for 5 to 10 days induced expression of WT p53 and p21 in tumor tissues, significant decrease of tumor volume (by 62.0 to 99.5%)and/or incidence of tumors, and complete suppression of metastasis. Intravenous administration of p53 gene in DNA dose of up to 12 mg/kg to rats didn't induce significant acute or sub-acute toxicity as demonstrated by survival body weight, laboratory studies, and histologic analysis of vital organs. Trans-hepatic arterial administration of p53 in DNA dose of 0.5 to 5 mg per kg induced expression of human WT p53 in rabbits liver and/or lung and didn't induce significant hepatic toxicity or systemic toxicity. Trans-hepatic arterial administration of p53 gene in DNA dose of 1 mg per kg induced significant decrease of tumor incidence (to 40%) and volume (to 0.4% of control) and suppression of metastasis of rabbits liver VX2 carcinoma which carry point mutation of p53. These results suggested that our cationic polyliposome-mediated p53 gene trasfer might be a promising treatment modality for human cancers which carry mutation of p53. Based on the results of basic research, we carried out a pilot study to investigate antitumor efficacy and safety of cationic liposome-mediated p53 gene therapy in patients with liver cancer. Patients whth advanced, primary (N=12) or metastatic (N=4) liver cancer who had failed conventional therapy underwent p53 gene therapy, of whom 12 showed mutation of p53. Patients with advanced liver cirrhosis or metastasis were also included in the study. Fifteen patients with advanced liver cancer who underwent hepatic angiography alone served as control. p53 gene was administered in complex with HECH : DOPE : PLL into common hepatic artery in DNA dose of 10 to 30 mg every 3 to 4 weeks for 2 to 8 times (mean 4 times). Of 16 patients who underwent p53 gene therapy, 6 showed partial response, 4 minimal response and 3 stable disease. High level expression of WT p53 or p21 were found in tumor tissues of hepatovectin1 administered patients. After p53 gene therapy, 11 of 16 patients developed transient fever and chill, but none developed transient fever and chill, but none developed grade 4 toxicity or deterioration of liver function. Of 16 patients who underwent p53 gene therapy, 7 were alive on 1 year follow up and 9 died from metastatic cancer or liver cirrhosis-related complications. in contrast, none of control group survived for 1 year. These results suggest that cationic liposome-mediated p53 gene trasfer via hepatic artery may become a promising therapeutic modality for advanced liver cancer which carry mutation of p53 gene. Our studies strongly suggest that our cationic liposome-mediated p53 gene therapy may be a promising treatment modality for human cancers which carry mutation of p53 gene and failed by conventional therapies. Further stydies are necessary on the actual benefit of this experimental study and effective systemic delivery method of p53 gene.

      • KCI등재

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