http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
박기령,조성민,우가은,이기현,손혜영,임정윤,최진혁,이순남,정화순 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.2
Chronic neutrophilic leukemia(CNL) is a very rare myeloproliferative disease, characterized by sustained mature neutrophilic leukocytosis with granulocytic bone marrow infiltration, high NAP(neutrophilic alkaline phosphatase) score and absence of philadelphia chromosome, It is frequently accompanied by hepatosplenomegaly, elevated serum vitamin B_12 and uric acid level. For the diagnosis of CNL, the leukemoid reaction, especially secondary to neoplasia, infection and autoimmune diseases, should be excluded. Since Tuohy's first description in 1920, more than 50 cases fullfilling the above criteria have been reported worldwide, and 4 cases in Korea. Several authors have demonstrated the defect of intracellualr killing in the mature neutrophil and this finding correlates well with the very high incidence of fatal infection, The hemorrhagic diasthesis in CNL is caused by functional abnormality of the platelet. This disease has tendency to transform to blastic crisis and acute leukemia as in other myeloproliferative disease, but characteristically shows frequent coexistence with multiple myeloma. Until now , the therapeutic trials in CNL have been disappointing. Hydroxyrea and busulfan can control hyperleukocytosis. On the basis of functional defect in neutrophil, alpha-2b-interferon has been tried and several reports have demonstrated the clinical and functional effect of interferon on CNL. CNL is very rate hematologic disease and there are few report about general aspect of disorder. We report here a typical CNL case presenting with splenomegaly and leukocytosis with a review of the literature.
설치류 뇌에서 c-Fos를 이용하여 삼투조절과 관련된 신경회로의 규명
이영기,박덕배,장가용 제주대학교 생명과학연구소 2000 제주생명과학연구 Vol.3 No.-
본 연구는 생쥐의 중추신경계통에서 고장액에 반응하여 c-Fos에 대한 면역양성을 나타내는 지역을 규명하고자 수행하였다. c-Fos의 발현은 면역조직화적으로 검출하고 신경세포의 활성화에 대한 표식자로 이용하였다. 고장액은 생쥐 뇌의 supraoptic nuclus, median preoptic nucleus organum vasculosum lamina terminalis, sufornical organ, locus coeluleus, nucleus of solitary tract, ventrolateral medulla, parabrachial nucleus 등에서 발현되었다. 특히 retrochiasmatic area의 배쪽 부분에서 많은 c-Fos면역양성의 세포가 관철되었으며, 시상하부의 paraventricular nucleus나 두뇌의 area postrema에서는 c-Fos면역양성세포가 거의 관철되지 않았는데 이들 지역들은 흰쥐에서는 다수의 c-Fos면역양성 세포가 나타나는 지역이다. 이상의 결과들은 생쥐에서 고장액이에 의해 c-Fos면역양성 세포가 나타나는 지역은 흰쥐에서와는 일부 상이한 결과를 보여주는 것으로 나타났다. Experiments were carried out on adult mouse to investigate the regional localization of the cells inducing c-Fos immunoreactivity in central nervous system in response to hypertonic saline(HS). c-Fos induction, detected immunohistochemically, was regarded as a marker for neuronal activation. Intraperitoneal injection of HS resulted in dense c-Fos-like immunoreactivity (FLI) in several forebrain and brainstem area. These areas include the supraoptic nucleus(SON), median preoptic nucleus (MnPO), organum vasculosum lamina terminalis(OVLT), subfornical organ(SFO), locus coeruleus(LC), nucleus of solitary tract(NTS), ventrolateral medulla(VLM), and parabrachial nucleus(PBN). In particular, the ventral region of retrochiasmatic area showed numerous and very intensely labeled FLI cells. No FLI or few FLI cells were, however, detected in the hypothalamic paraventricular nucleus (PVN) and the area postrema(AP) respectively, the regions which revealed very intensive FLI in rat after HS treatment. These data suggest that FLI induced in response to osmotic stimuli in the mouse brawn has a different regional distribution from that of rat brain.
윤혜원,심기남,나선경,송도경,정정화,정가영 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2
Double primary cancers are two independently developed cancers in an individual. There have been some reports on double primary cancer since Billroth reported it for the first time in 1879. Double primary cancer of the stomach and esophagus has been revealed a very low incidence worldwide. The incidence of an esophageal cancer with another primary cancer is reported to be 9.5∼27%, but double primary cancers in the esophagus and stomach have been rarely reported to our knowledge. In this study, we present here a case of double primary esophageal and stomach cancer in a 66-year-old man because of progressive dysphagia.
캡슐내시경과 단일풍선 소장내시경으로 진단된 공장의 간질종양 1예
송도경,심기남,태정현,김경진,송명은,송하응,윤혜원,정가영,정정화 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2
Gastrointestinal stromal tumors (GISTs) are common mesenchymal tumors that arise in the wall of the gastrointestinal tract. We report a case of obscure gastrointestinal bleeding due to a GIST of the jejunum successfully documented by videocapsule endoscopy (VCE) and single-balloon enteroscopy (SBE). A 36-year-old man with hematochezia was referred for further evaluation of no evidence of bleeding focus on esophagogastroduodenoscopy and colonoscopy. A VCE showed a suspicious ulcerative hyperemic mass that located in about 1 hour apart from duodenal second portion. SBE revealed a nonbleeding 4×2 cm mass with an ulcer at the proximal jejunum. The patient underwent laparoscopic resection without complication. Histological examination revealed a well circumscribed, dumbbell-shaped firm mass comprised of spindle cells. Immunohistochemical staining for CD 117 was diffusely positive, whereas staining for S-100, CD 34 and MIB-1 was all negative. It was confirmed to be a low-grade GIST at the proximal jejunum.
The Changing Roles of Women Officers in Public Order Policing in Hong Kong
Ho Ka-ki,Chu Yiu Kong 아시아경찰학회 2006 아시아경찰학회 국제학술회의 Vol.2006 No.-
The police are regarded as a male-dominated mescaline profession. Western police studies tend to suggest that women officers will face role-conflicts when they enter the male-dominated masculine occupation and they only play a complementary role in the public order policing. The Hong Kong Police Force was established in 1844. Women police officers were never perceived as indispensable component by early British colonial police heads. The first women officer had not been recruited until 1949. Yet, in 1950s and 1960s duties assigned to female cohorts were confined to supporting duties such as conducting clerical jobs, handling female suspects and taking care of wandering children rather than law enforcement and anti-riot operations. On the top of this, sexually segregated and discriminatory arrangements could also be easily noted in reviewing the managerial history of the Hong Kong Police. This study finds that the role of women officers started to change in late 1960s, especially in the sphere of public order policing. For instance, women police officers took up some frontier positions in the 1967 riots. They received formal anti-riot training since 1970s. A female anti-riot squad was formed in 1992. Since 1995 all newly recruited Hong Kong women police officers have been armed. In 2005 women police officers were placed in the front to deal with Korean demonstrators directly during the WTO MC6 period. The evolving responsibilities of female police officers from indoors administrative work to frontier crowd management duties not only reflect the changing attitude towards women in Hong Kong society, but also signify the vitalization of women officers in policing Hong Kong. The data of this research are largely derived from archival materials and in-depth interviews with 12 women police officers who served the force from 1950s to 1980s.
오기원 ( Ki Won Oh ),윤은주 ( Eun Joo Yun ),오은숙 ( Eun Sook Oh ),이성규 ( Seong Kyu Lee ),김상우 ( Sang Woo Kim ),이덕철 ( Duk Chul Lee ),노성일 ( Sung Il Roh ),이원영 ( Won Young Lee ),백기현 ( Ki Hyun Baek ),강무일 ( Moo Il Ka 대한내과학회 2003 대한내과학회지 Vol.64 No.2
목적: 폐경 후 여성에서 급성 폐경 증상의 완화 및 골다공증의 예방과 치료를 위하여 여성호르몬 대체요법이 광범위하게 사용되고 있으나 유방통, 자궁출혈, 체중증가 등의 일시적인 부작용으로 인하여 초기에 치료가 중단되는 경우가 많다. 또한 기존의 여성호르몬 대체요법의 심혈관계질환 예방효과 및 유방암 위험도 증가에 대하여도 많은 논란이 있다. 저용량 난포호르몬치료는 골량이 보존되면서도 부작용 감소가 관찰되고 있으며, 미세화 황체호르몬의 사용은 합성황체호르몬치 Background: Hormone replacement therapy in postmenopausal women is widely used for the relief of menopausal symptoms and the prevention of bone loss. But, it has been reported that many women discontinue hormone replacement therapy within early period, be