중부지역 옥수수 파종기에 따른 생육단계 및 수량성 변화

서종호, 문중경, 정건호, 서민정, 구자환, 박장환, 배환희, 신성휴, 권영업 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

Maize hybrids were planted on April 1, April 25, May 20 and June 15 in 2012, 2013 at the experimental paddy and upland fields in Suwon city , respectively to know changes of growth stage and yield according to different planting time. Maize planting on April 1 was not recommended because total growing days at planting on April 1 was not different with that at planting on April 25 due to many days from planting to emergence over 20 days at planting on April 1. Total growing days were not much different among three planting time after April 25 because days from silking to maturity was lengthened though days from planting to silking was shortened at later planting time. Stalk weight was decreased as planting time was delayed, particularly at planting times after May 20 at paddy field by excess water injury during early growth stage. But, grain yield was not low as in May and June. It is needed to introduce early maturity maize variety as Yanganok at late planting for higher grain yield and enough time for soil preparation for next winter crops

비만증 환자에서 한약제에 의한 체중 감소효과

Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

그루지아 민가의 전통 발효유에서 분리한 유산균의 이화학적 특성

신승이,최기춘,김종현,박정수,이영환 全南大學校 農業科學技術硏究所 1999 農業科學技術硏究 Vol.34 No.-

그루지아의 전통 발효유로부터 유산 생성과 항균성이 우수한 3주의 균주를 최종 분리, 선발하고 각각 Lactobacillus bulgaricus (L bulga G82), Lactobacillus acidophilus (L. acid G86), 그리고, Streptococcus thermophilus (S. thermo G90)로 동정하였다. 이들 유산균을 starter로 요구르트를 제조하여 이화학적 특성을 조사한 결과, pH는 4.0∼4.5의 범위를 보였으며, pH 4.0으로 L. acid G86 균주가 가장 낮게 나타났다. 또한 0.1N HCl에 대한 완충능은 4.50∼5.12ml, 0.1N NaOHdp 대한 완충능은 3.74∼4.98ml의 범위를 보였고, 3 균주 중 L acid G86 균주가 산-염기에 대하여 가장 높은 완충능을 나타내었다. 산도는 0.95∼1.16%, 점도는 1,984∼2,232 cps 그리고 생균수는 1.4x109∼3.0x109으로 조사 되었다. in vitro에서의 콜레스테롤 저하 정도는 L. acid G86 균주가 약 35%로 가장 높은 저하 정도를 보였고, L. bulga G82와 S. thermo G90 균주는 각각 약 32%, 24%이었다. Three strains of inhibitory lactic acid bacteria against pathogenic microorganism were isolated from traditional fermented milk of Georgia, and than, identified to be Lactobacillus bulgaricus (L bulga G82), Lactobacillus acidophilus (L acid G86) and Streptococcus thermophilus (S. thermo G90), respectively. These strains were used to starter for yogurts. So, we made yogurts, and evaluated their phyco-chemical properties. The range of pH value was 4.0∼4.5, and L. acid G86 strain was the lower pH value for 4,0. The buffer capacity against 0.1N HCI and 0.1N NaOH were 4,50~5.12ml and 3.74~4.98ml. The acidity, viscosity and viable cell counts of yogurt were 0.95∼1/16%, 1.984∼2,232 cps and 1.4x109∼3.0x109, respectively. Among the three strains, L. acid G86 strain was have the best ability of lowering cholesterol level in vitro, the value were about 35%. The L. bulga G82 and S. thermo G90 were around 32% and 24%, respectively.

대형 화재로 인한 사상자의 손상 유형과 합병증 : 동인천 라이브호프 화재를 중심으로

신중호,김재광,염석란,신종환,민순식,임용수,양혁준,이근,황성연 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: High risks of fire alway exist for buildings in urban areas, especially those in downtown. Crowds, as well as more complex and larger structures, may cause more victims in the event of fire; therefore, emergency medical service plans must be established for such disastrous events. Methods: On the evening of October 30,1999, a fire broke out in downtown, Dong-Incheon Live-Hof restaurant; 56 people were killed and 76 were injured. Most of them were teenagers. We retrospectively reviewed the medical records of the victims, Results: 1) Among the 56 dead, 54 died from smoke inhalation, one from extensive burns, and one from sepsis during treatment. 2) Among the 76 injured, 70 patients suffered from smoke inhalation, 53 from burns, and 9 from several types of trauma (sprains, contusions, lacerations, abrasions, fractures, etc.). 3) Later complications were laryngeal edema, pulmonary edema, scar contracture, and hypoxic brain damage, and so forth. 4) Post traumatic stress syndrome was unexpectedly more prevalent in mildly to moderately injured survivors and witnesses than in seriously injured survivors. Conclusion: Many complications exist after a fire. Some may be resolved in time, but others may result in permanent sequelae. Early rescue, early triage, and early management during transport by emergency medical service (EMS) personnel can result in fewer complications and a lower mortality rate. Therefore, we propose the establishment of plans to be followed during various major disasters.

Ethanol Patch Test와 음주 후 불편감과의 관계에 대한 연구

신재정,장환일,김경빈 大韓神經精神醫學會 1989 신경정신의학 Vol.28 No.1

It has been well known that alcoholism is influenced by multiple factors such as biological, social and familial factors. Recently many researches are focusing on further investigation of biological aspects, especially on enzymes of acetaldehyde metabolism. The low Km aldehyde dehydrogenase(ALDH-I) has been implicated to play a major part in the metabolism of acetaldehyde. Therefore ALDH-I deficiency has been assumed to give rise to aversive effects to alcohol which are caused by a high blood acetaldehyde concentration. Recently Ethanol Patch Test(EPT) was suggested as a screening test to dectect ALDH-I deficiency. The mechanism of skin erythema of EPT is presumed to involve vasodilatatlon due to an accumulation of acetaldehyde in the skin. The lack of ALDH-I in the skin may be responsible for the delayed metabolism of acetaldehyde. This study was designed to evaluate the relationship between time of disappearance of skin erythema in EPT and aversive effects to alcohol in 38 alcoholic patients and 42 control subject. The results was as follow : 1) The difference of total lenght of times of disappearance of skin erythema in EPT between two groups was significant. 2)When a patch area showed erythema 10 minutes after removal, it was judged to be ALDH-I dificiency. 10.52% of alcoholic patients and 32.55% of control subjects were catergorized as ALDH-I deficient. 3) When the results of EPT were compared according to response degrees on each item in two groups, significant items were No. 1, 2, 14. 4) When the results of EPT were compared according to total scores on each dimension in two groups, physiological aversive and psychological aversive dimensions were significantly correlated only in control subjects.

부산 서구 저탄소 녹색도시사업을 통한 지역환경 개선 및 활성화 방안 연구

정숙진, 윤성환, 우신구 신라대학교 부산학연구센터 2012 부산연구 Vol.10 No.-

전 세계의 환경문제인 기후변화에 적극적으로 대응하기 위해 새로운 국가 비전인 저탄소 녹색도시을 견인할 수 있는 지역·권역별 녹색도시화 특성화 방안을 제시함으로서 기후변화에 대응할 수 있는 방안을 모색하고자 한다. 부산 원도심인 서구 충무동·남부민동의 풍부한 자연자원과 다양한 역사·문화자원을 활용한 저탄소 녹색성장과 환경보호를 양립시켜 새로운 성장동력과 지역경제 활성화로 도시재생방안을 마련한다. 녹색기술을 활용한 경사지 주거재생, 도심형 항만재생, 원도심 상권재생의 3대 목표를 설정하고 6대 핵심 전략을 중심으로 지속가능한 녹색도시를 조성한다. 서구 저탄소 녹색도시 선도사업에서 노후화된 주거시설을 개선하기 위한 하우스 프로젝트을 통해 지역성에 맞는 주거모델을 제시하고 친환경 기술요소를 이용하여 자체에너지 생산, 그린 인프라를 이용하여 생태복원 및 바람길을 연결하여 미기후 조절을 가능하게 한다. 그리고 도심형 항만재생에서는 공동어시장에 발생하는 유기성폐기물을 바이오매스시스템 구축을 통하여 바이오에너지를 생산하며 해양친수공간 조성과 천마산을 연결하는 그린네트워크를 형성하여 부산의 대표적인 저탄소 녹색성장 명품도시로 조성한다. By suggesting the green city characterization measure for each region and zone that can lead the low carbon green city which is a new national vision in order to actively cope with the climate change, the global environment issue, we aim to seek for the measure to build up low carbon green city suitable for local characteristics. With low carbon green growth and environment protection by using abundant natural resources and various historical/cultural resources in Seo-gu Chungmu-dong and Nambumin-dong, the old downtown of Busan, the city reclamation measure can be prepared based on a new growth driving force and local economic vitalization. It is a general measure related to easing and adapting to climate change like water circulation, including setting up the three main goals like reclamation of residence on slopes, urban ports and business districts in old downtown based on green technology, and the six core strategies like establishing system of carbon reduction through using low carbon energy, improving the transportation structure through introducing green traffic system, having water/resource circulation system through low carbon circulation resource, having green construction system through applying green technology and environmentfriendly materials, building up ecotype greens based on the carbon absorption system through management of greens and urban forest and creating green community through private and public green partnership. It is possible to control microclimate by connecting wind ways, restoring ecology through using green infrastructure and producing its own energy based on environment-friendly technical elements as also suggesting residental models suitable for local characteristics based on the house project to improve obsolete residential facilities with low carbon green city leading project in Seo-gu. For the urban port reclamation, bio-energy is produced by building up biomass system through organic waste generated in the joint fish market. As also forming waterfront and green network connecting with Mt. Cheonma, it can be the representative low carbon green growth city in Busan.

스테인 에칭기법을 이용한 실리콘 마이크로머시닝

설정훈,신장규,심준환,류인식,이종현 경북대학교 센서기술연구소 1994 센서技術學術大會論文集 Vol.5 No.1

스테인 에칭기법을 이용하여 실리콘의 도핑 농도가 높은 영역을 선택적으로 식각하는 방법을 개발하였다. 이 방법은 양극 반응을 이용한 마이코로머시닝 방법에서와 같이 반응 시편의 뒷면에 전극을 연결하거나 특수한 반응기를 이용해 전류를 공급할 필요성이 없으므로 공정 단계가 간단해지고 표준적인 집적회로 공정에서도 응용될 수 있을 것이다. 또한 양극반응에서는 불가능한 n^(+)/p 구조 시편의 선택적인 식각도 가능하다. 본 연구에서는 스테인 에칭기법을 이용하여 n/n^(+)/n 3층 구조의 시편으로 켈틸레버 및 에어 브릿지 등을 실현하므로써 미세기계구조의 제조 가능성을 확인하였다. We have developed a preferential silicon etching method using stain etching technique. Current supply to the backside contact of silicon wafer and special reactor are not required in this method. Therefore this method is much simpler than anodic reaction method and could be applied to standard VLSI process. In addition, the n^(+) layer in n^(+)/p structure could be preferentially etched by this technique, which could not be implemented by anodic reaction method. We have also fabricated micromechanical structures like cantilevers and air-bridges on the n/n^(+)/n wafer using this stain etching technique.

Impact of lifestyle factors on trends in lipid profiles among Korean adolescents: the Korea National Health and Nutrition Examination Surveys study, 1998 and 2010 Shin-Hye

Kim, Shin-Hye,Song, Young-Hwan,Park, Sangshin,Park, Mi-Jung The Korean Pediatric Society 2016 Clinical and Experimental Pediatrics (CEP) Vol.59 No.2

Purpose: Only a few studies have explored nationwide trends in lipid profiles among Asian adolescents. We aimed to assess trends in lipid profiles and the associated lifestyle factors among Korean children. Methods: We analyzed data for 2,094 adolescents who were aged 10-18 years and had participated in the Korea National Health and Nutrition Examination Surveys in 1998 and 2010. Results: During 1998-2010, the prevalence of obesity significantly increased in boys, but no changes were observed in girls. Over this period, there was a small but significant decrease in the mean lowdensity lipoprotein (LDL)-cholesterol level in boys (1998, 87.5 mg/dL; 2010, 83.6 mg/dL; P=0.019) and mean triglyceride levels in girls (1998, 90.8 mg/dL; 2010, 85.8 mg/dL; P=0.020). There were no significant changes in the prevalence of dyslipidemia in boys, but a modest decrease was noted in girls (1998, 25.1%; 2010, 18.3%; P=0.052). During the study period, the prevalence of breakfast skipping decreased, whereas that of regular exercise increased in both groups. Daily total energy intake did not change between these years. In multivariable logistic regression analyses, breakfast skipping was associated with increased risk of hyper-LDL-cholesterolemia in boys (odds ratio [OR], 5.77) and hypertriglyceridemia (OR, 2.27) in girls. Regular exercise was associated with decreased risk of hypo-HDL-cholesterolemia (OR, 0.40) in boys. Conclusion: Although the prevalence of obesity in boys increased, favorable or constant trends in lipid profiles were observed among Korean adolescents during 1998-2010. Decrease in breakfast skipping and increase in regular exercise may have contributed to these trends.

중증 재생불량성빈혈에서 타인 혹은 HLA 불일치 혈연간 골수이식을 위한 cyclophosphamide와 antithymocyte globulin전처치 요법

이정희,이제환,김신,설미이,이정신,김우건,김상희,지현숙,박찬정,이규형 대한조혈모세포이식학회 2001 대한조혈모세포이식학회지 Vol.6 No.1

배경: Cyclophosphamide와 ATG의 전처치 요법은 HLA가 일치하는 형제간 골수이식에서는 매우 효과적인 것으로 알려져 있으나, 타인 혹은 HLA 불일치 혈연간 골수이식에서는 전처치 요법으로서 불충분한 것으로 보고되었는데, 주요 문제는 착상 부전이었다. 우리나라를 포함하는 극동아시아 지역의 국가들에서 발표되는 보고에 의하면 타인이식을 포함하여 골수이식 후 착상 부전과 이식편대숙주질환의 발생이 서구 국가들로부터의 보고에서보다 적은 것으로 알려져 있다. 저자 등은 6예의 중증 재생불량성빈혈 환자들에서 질병 초기에 Cyclophosphamide와 ATG만을 이용하여 전처치를 한 후에 타인 혹은 HLA 불일치 혈연간 골수이식을 시행하였다. 방법: 1999년 5월부터 2000년 4월까지 서울중앙병원에서 타인 혹은 HLA 불일치 혈연간 골수이식을 시행 받은 성인 중증 재생불량성빈혈 환자들을 대상으로 하였다. 골수이식을 위한 전처치 요법으로 cyclophosphamide (50 mg/kg/d x 4)와 ATG (30 mg/kg/d x 3)를 투여하였는데, 골수이식 전에 ATG에 대하여 과민 반응을 보였던 한 예 (UPN 120)에서는 ATG 대신에 fludarabine (30 mg/m2/d x 3)을 투여하였다. 이식편대숙주질환의 예방을 위하여 cyclosporine과 methotrexate를 투여하였다. 결과: 연구 기간 중에 모두 6예가 타인 혹은 HLA 불일치 혈연간 골수이식을 시행 받았는데, 5예는 타인으로부터 골수를 공여 받았으며, 1예는 HLA의 표현형이 하나의 유전자좌에서 일치하지 않는 형제로부터 골수를 공여 받았다. 타인 골수이식을 받은 5예 중에서 3예의 공여자는 HLA의 표현형이 일치하였으며, 1예는 하나의 유전자좌가 major mismatch였고, 1예는 하나의 유전자좌가 minor mismatch였다. 추적기간의 중앙값은 406일 (범위, 328-643일)인데, 6예 모두에서 착상된 상태를 유지하면서 생존해있다. 2예에서 3도의 급성 이식편대숙주질환과 전신성 만성 이식편대숙주질환이 발생하였다. 결론: Cyclophosphamide와 ATG의 전처치 요법은 재생불량성빈혈의 초기에 타인 혹은 HLA 불일치 혈연간 골수이식을 시행 받은 한국인 환자들에서 충분히 착상을 가져올 수 있는 요법으로 생각된다. 비록 본 연구의 대상 환자 수가 적지만 결과는 매우 고무적이다. HLA가 일치하는 형제가 없는 중증 재생불량성빈혈 환자의 경우에 타인 골수 공여자에 대한 검색을 조기에 시행해야 하며, 타인 혹은 HLA 불일치 혈연간 골수이식을 질병 초기에 적극적으로 고려해야 할 것으로 생각된다. Background: Cyclophosphamide (CY) and ATG regimen was reported to be insufficient for alternative donor BMT in SAA patients due to high incidence of graft rejection. The rates of graft rejection and GVHD after allogeneic BMT including unrelated donor transplants seemed to be lower in reports from Asian countries of Far East. We applied CY/ATG regimen to six patients with early stage of SAA transplanted with marrow from alternative donors other than HLA-identical siblings. Methods: Three patients were transplanted from HLA-phenotypically identical unrelated donors, two from one-locus mismatched unrelated donors, and one from an one-locus mismatched sibling donor. Four patients received no previous therapy for SAA, and two received one course of immunosuppressive therapy with ATG. Preparative regimen was CY (200 mg/kg) plus ATG (90 mg/kg) in all patients except one who had had an anaphylactic reaction to ATG prior to BMT and received fludarabine (90 mg/m2) in place of ATG. Cyclosporine plus methotrexate were given for GVHD prophylaxis. Results: All six patients engrafted and all are alive with durable engraftment at a median follow-up of 406 days (range, 328 to 643). Two patients developed grade III acute GVHD and extensive chronic GVHD. Conclusions: CY/ATG regimen may be sufficient in Korean patients with early stage of SAA transplanted with marrow from alternative donors. Although the number of patients in present study is small, results are encouraging. Stem cell transplantation using alternative donors may be considered at early stage of aplastic anemia.

Oxantel/Pyrantel 合劑 및 Mebendazole에 依한 腸內線蟲類 驅蟲效果에 對한 比較實驗

金鍾煥,辛大煥,林定圭 충남대학교 의과대학 지역사회의학연구소 1978 충남의대잡지 Vol.5 No.1

A total of 63 subjects with multiple intestinal nematode infection: T. trichiura, A. lumbricoides, E. vermicularis and T. orientalis were treated with Oxantel/Pyrantel suspension and Mebendazole. The administration of Oxantel/Pyrantel suspension was 15mg/kg body weight in a single dose and Mebendazole was 600mg, divided by 100mg, twice daily for three consecutive days regardless of the body weight or ages. The results of present trials are summarized as follows: 1. The egg negative conversion rates for Oxantel/Pyrantel suspension were 100% in 20 cases of Ascariasis and in 3 cases of T. orientalis infection, and 92.3% in 26 cases of Enterobiasis. The egg reduction rate of T. trichiura was 84.8%. 2. The Mebendazole treated group showed the egg negative conversion rates of 100% in 27 cases of Ascariasis and one case of Trichostrongyliasis, 88.5% in 26 cases of Enterobiasis and 19.4% is 32 cases of Trichuriasis. The egg reduction rate of T. trichiura was 89.4%. 3. With the Oxantel/Pyrantel treated group, adult worms were found T. trichiura 1449 (average 45.3), A. lumbricoides 81 (av. 4.1) and E. vermicularis 249 (av. 9.6) worms. In Mebendazole treated group demonstrated the number of adult worms: 406(av. 13.1) of T. trichiura, 79 (av. 2.9) of A. lumbricoides and 134 (av. 5.2) of E. vermicularis, respectively. 4. Side effects of both Oxantel/Pyrantel and Mebendazole were few and mild.