Azathioprine에 반응을 보인 류마티양 관절염에 의한 경막염(Pachymeningitis)1예

배광봉,이정호,이정찬,곽상혁,강정현,김철희,김현수,김종숙,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1999 충남의대잡지 Vol.26 No.1

Rheumatoid arthritis frequently involves the cervical spine and may lead to neurologic impairement. However, direct involvement of CNS structures by inflammatory cells has been reported infrequently. The prevalence of this complication of rheumatoid arthritis is unknown. Inflammatory CNS involvement in rheumatoid arthritis reportedly occurs in the setting of longstanding, active, erosive articular disease and is accompanied by extracranial and extraspinal nodules and vasculitis. This is diagnosed by radiologic finding of CNS nodules or meningeal thickening and by biopsy or autopsy. Treatment with corticosteroid, cytotoxic agent or surgical decompression is helpful. But the majority of patients die within several months of onset of neurologic symptom. Recently, we experienced a case of pachymeningitis caused by rheumatoid arthritis, which resolved repeatedly with azathioprine treatment.

유치화 계승영구치의 근원심 폭경에 관한 연구

배찬주,이종갑 大韓小兒齒科學會 1985 大韓小兒齒科學會誌 Vol.12 No.1

The mesiodistal crown diameters of the decidious teeth and their permanent successors have been studied and analyzed about the mean size, percentage and the correlotion coefficient from the longitudinally collected 104 stone models of E. elementary school children. The results were as follows: 1. The mean values of deciduous teeth and their permanent successors were slightly larger in males than in females and statistical differences of males and females were found in some teeth. 2. In the percentage of deciduous and permanent successors, the smallest were lateral incisor in male, central incisor in female and maxillary 2nd deciduous molar, mandibular 1st and 2nd deciduous molar were larger than their permanent successors. 3. In the percentage of corresponding teeth groups, maxillary incisors were smaller than their successors and in maxillary buccal teeth were similar to their successors, and in mandibular buccal teeth the sum of deciduous teeth were larger than that of permanent teeth about 10%. 4. Individual correlations of deciduous tooth and their permanent successor was relatively low. The same tendencies were found at corresponding teeth groups. 5. In the differences between the corresponding teeth groups, the sum of permanent incisors were largest to their deciduous teeth but the sum of mandibular buccal teeth were the smallest. 6. The correlations for the differences of corresponding teeth groups were negative correlated with high value.

당뇨병 환자의 안면부 파라핀 주사부위에 발생한 피부 모균병

김종현,황소민,전재용,배용찬 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

Mucormycosis is an opportunistic fungal infection caused by the mucorales, which consist of the Rhizophus, Absidia, Mortierella, and Mucor. The diverse clinical forms of mucormycosis can be categorized as rhinocerebral, pulmonary, disseminated, gastrointestinal, cutaneous and miscellaneous. Although it can cause disease in healthy people, it most commonly affects patients who are diabetic or immunosup-pressed. Rarely, mucormycosis develops confined to the subcutaneous tissue. We experienced a case of cutaneous mucormycosis developed in a well-controlled diabetic patient who had previously injected foreign material on her face for an aesthetic purpose at the behest of an unlicensed physician. The patient had tissue necrosis and purulent discharge on her left cheek. Following histologic examination, we diagnosed the condition as cutaneous mucormycosis and treated it by wide excision combined with amphotericin B therapy. The disease was cured without any significant sequelae within 6 months of follow up. Cutaneous mucormycosis is rarely reported but it can cause facial deformity due to tissue necrosis, so that early diagnosis and appropriate treatment are important. Currently, foreign material injection for aesthetic purposes is still performed by unlicensed physicians. We present a case report concluding that one should consider the possibility of fungal infection in skin lesion in diabetic or other immunosup-pressed patients. We also emphasize the seriousness of illegal injection of foreign material.

삼천지의 곤충상

이종욱,류성만,서경인,전영태,배찬영 嶺南大學校 基礎科學 硏究所 1998 基礎科學硏究 Vol.18 No.-

We studied insect fauna in the Samchun-impoundment during the period of from September 1997 to August 1998. The total number of insect taxa are composed to 95 species in 86 genera, 39 families and 8 orders in this examination.

위발성 위장관 악성림프종 환자에서 항암치료의 효과

김찬규,신영록,김현정,배상병,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Purpose: The gastrointestinal (GI) tract is the most common site of extranodal non-Hodgkin's lymphoma (NHL), which is increasing in incidence, but there is no established optimal treatment modality. Thus, this study was investigated the clinicohistologic feature, the therapeutic modalities, and the prognosis for GI-NHL, as well as the factors affecting it. Methods: We retrospectively analyzed 45 patients who had been diagnosed as having GI-NHL and had been followed up from July 1994 to February 2005 at Soonchunhyang University Hospital. The patients were divided into groups according to the site of origin and to various other features, and the survivals of the various groups were compared. The modified Ann Arbor system and WHO classification were adopted for staging and histopathologic classification, respectively. Results: GI-NHL of the stomach, small bowel, ileocecal region, and colon occurred in 28 patients (62.2%), 5 patients (11.1%), 3 patients (6.7%), and 8 patients (17.8%), respectively, In one patient, the entire gastrointestinal tract was diffusely involved. The median age of patients was b5 years (25~78 years), and male-to-female ratio was 1:1.1. Fourteen patients were in stage Ⅰ, 24 in stage Ⅱ, 4 in stage Ⅲ, and 3 in stage Ⅳ. Surgical resection was performed in 19 patients, and combination chemotherapy was performed in 43 patients. Surgical resection only was performed in 4 patients, Chemotherapy only was performed in 26 patients. The expected overall 5 year survival of 45 patients was 39.6%, and there was a significant survival difference between the stages, but between sites of origin (p=0.842). The most important factors influencing the survival was the stage and other factors were not significant. Conclusion: The stomach was the most common site of GI-NHL. Most GI-NHL were localized Stage was the most important prognostic factor. However, Prospective randomized studies are needed to approve the therapeutic modality.

환경농업조성지구내 용수원 및 채수시기별 수질비교

김찬용,김창배,김종수,서영진,윤재탁 한국환경농학회 2002 한국환경농학회지 Vol.21 No.3

A study was conducted to investigate the seasonal changes in water quality of watershed in the Agricultural Environment Promotion Zone. samples collected were 12 GW (ground water), 2 IW (irrigation water), 2 SW (stream water) in An-Doug City, 4 GW, 6 IW, 11 SW in Young-Yang Gun, and sampling was conducted separately during dry and rainy season. In the ground water, EC and ionic species, except pH, were higher than those in stream water, and especially NO_3-N concentration exceeded the limitation of drinking water. Concentration of ions decreased as the sampling depth was far from the soil surface. During a rainy season, the concentrations of NO_3-N and K In the stream water were slightly higher than those during season. COD was lower during dry season in Yong-Yang, while the trend was contrasted to An-Doug. These results suggest that ground water was polluted by fertilization and compost while streamwater was polluted by loss of soil and organic during the rainy season. Principal chemical components related with changing water quality were EC, NO_3^-, Ca, Mg, Na, CI^-, SO_4^- in ground water, whereas NH_4-N, K, Mg, CI^-, SO_4^- in stream water.

고요산혈증의 위험인자 : 아산시 지역 주민을 대상으로

김용배,장원기,황보영,김화성,안규동,이병국,이용진,이종은,이준숙,이찬구,이한정,이성수 순천향대학교 2006 Journal of Soonchunhyang Medical Science Vol.12 No.1

Objective : Serum uric acid has now been identified as a marker for a number of metabolic and hemodynamic abnormalities. The aim of this study is to evaluate risk factors which influence hyperuricemia in the citizens of Asan. Method : The study design was cross-sectional and research subjects were 1086 citizens of Asan. General characteristics, cigarette smoking, alcohol consumption, and past history were obtained by interview using a structural questionnaire. Also, we measured height, weight and blood pressure, and serum uric acid of the subjects. Results : The mean serum uric acid level was 5.27 ㎎/㎗ in men and 4.01 ㎎/㎗, in women, In the multiple logistic regression analysis, statically significant risk factors of hyperuhcemia were gender, body mass index, blood lead concentration, and serum creatinine. Conclusion : Our results suggest that gender, body mass index, blood lead concentration, and serum creatinine might be the most important risk factors of hyperurcemia. Education program as well as routine check-up for serum uric acid was highly recommended for the effective prevention of hyperuricemia.

철근콘크리트 전단벽체의 형식에 따른 구조성능 평가

全燦穆,權重培,申鍾學,河基柱 慶一大學校 1996 論文集 Vol.13 No.2

In this study, nine reinforced concrete infilled frames involved bare frames were tested during vertical and cyclic loads simultaneously. This test programs were carried to investigate the horizontal strength and the crack propagation in variance with hoop reinforcement ratio. All specimens were modeling in one-third scale size. In this experimental program structural performance of reinforced concrete shear wall were focus at connection types. Based on the test results, the following conclusions are made. (1) In fully rigid frame, increasing the ratio of hoop bar 2∼3 times on the basis of its ratio of in column(p??=0.196%). The horizontal strength of specimen did not varied, but the increased ductility of specimens were showed greatly at the final failure. (2) In the boundary column menber of reinforced concrete shear wall, increasing the ratio of hoop bar in two or three times, in the fully babel type, the shear and horizontal strength of specimens were increased 1.1-1.2 times than that of fully rigid frame. And infilled shear wall specimen were increased 1.17-1.27 times than that. (3) Fully rigid babel type shear wall specimens were increased 5.7∼8.0 times, and infilled shear wall specimens were increased about 4.0∼5.6 times in comparision with the full rigid frame.

재발 또는 불응성 비호즈킨 림프종 환자에서 CDME 구제항암화학요법 후 고용량 항암화학요법 및 자가말초혈액 조혈모세포이식의 효과

김세형,한강원,배상병,김찬규,이남수,이규택,박성규,원종호,홍대식,박희숙 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Background and objectives : The long-term survival in patients with non-Hodgkin's lymphoma (NHL) after conventional dose chemotherapy is about 35% and the rest of the patients tend to have relapse. So, in relapsed or refractory NHL, we compared the outcome of patients undergoing high-dose chemotherapy with autologous peripheral blood stem cell transplantation(APBSCT) with only salvage chemotherapy of cisplatin, dexamethasone, mitoxantrone, and etoposide(CDME). Materials and methods : From June 1993 to December 1999, 25 patients with relapsed or resistant NHL were treated with CDME regimen as salvage chemotherapy. Twelve patients were received four cycles of CDME chemotherapy, and 13 patients were received high-dose chemotherapy with APBSCT following two cycles of CDME chemotherapy. Results : The median follow-up duration was 12.8 months(range:4-68). The overall response rate was 41.7% (complete response rate 25%, partial response rate 16.7%) in 12 patients with CDME only. Thirteen patients who were treated with high-dose chemotherapy with APBSCT achieved 61.5% complete response rate and 15.4% partial response rate, with an overall response rate of 76.9%. The estimated 3-year progression-free survival rate was significantly higher among patients who received high-dose therapy than patients who received CDME only(41.5% vs 20.0%, p<0.05). And, 3-year overall survival rate was significantly higher among patients who received high-dose therapy(51.3% vs 25.0%, p <0.05). Conclusions : In relapsed or refractory NHL, CDME chemotherapy is an effective salvage chemotherapy and allow peripheral blood stem cell collection. Also, high-dose chemotherapy with APBSCT following CDME is superior to CDME salvage chemotherapy only.

최근 8년간 K지방대학병원 응급실로 내원한 치과 응급환자에 관한 임상적 연구

유재하,김종배,김태우,문선재,권혁찬,김승범 大韓顎顔面成形再建外科學會 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.6

The delivery of the proper care to the emergency dental patients is more important in the aspdect of community dental service. To attain such a purpose requires the sacred duty to the training of oral and maxillofacial surgeons. This is a retrospective study on the characteristics of dental injuries and diseases in emergency patients. Ths study was based on a series of 2,649 patients treated as dental emergency patients at K country hospital of medical college, from Jan. 1, 1993, to Dec. 31, 2000. The obtained results were as follows. The trauma(71.6%) was the most frequent cause in dental emergency patients, odontogenic infection and oral hemorrhage were next in order of frequency. The primary interdental wiring and transpalatal wiring were frequent proper methods with rubber drainage for prevention of hemorrhage and infection in the primary care of jaw fracture. The peak incidence(45.0%) about the infection group was occurred in the pulpitis of advanced dental caries, and common treatments were the medication of antibiotics & anagesics and I&D. In the dentoalveolar hemorrhage group, a major cause was postoperative hemorrhage(57.9%) and hemostasis was obtained by pressure dressing, suture and drainage of infected wound. About TMJ disorder group, the peak incidence was showed in the post-traumatic myofascial pain dysfunction syndrome and its primary care was medications(anagesics & sedatives). In the other groups, various irritable specific pains were complained, such as trigeminal neuralgia-form pain, acute stomatitis, chemical burn, terminal stage neuritis of head & nech cancer and their primary care methods were various individually. For the rapid and correct care of the emergency dental disease above, well-trained education should be presented in the intern and resident curriculum of oral & maxillofacial surgery.