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Raman 산란에 의한 InxGa1-xAs/GaAs 이종접합구조의 구조적 특성 연구
손정식,문영희,배인호,김말문 嶺南大學校 基礎科學硏究所 1996 基礎科學硏究 Vol.16 No.-
Using Raman Scattering, we have measured the resiual strain of InGaAs layers with 0≤ x < 0.33 grown on GaAs substrates. The samples under investigation were grown by molecular beam epitaxy system. The In composition was varied from x=0 to x<0.33 and the thickness of epilayer is fixed to 1㎛ which are more thick than critical layer thickness except bulk GaAs(x=0). Our result show that FWHM of GaAs-like LO phonon peak is not significant increase under 80% relaxation but TO/LO ratio is increase with In composition. We calculated relaxation ratio from Raman scattering measurements based on the theory of strain induced phonon shifts and which result compared with DCX measurements.
Platelet-Rich Plasma (PRP)가 토끼 척골의 분절 결손의 치료로 이식된 동종 장관골의 골유합에 미치는 효과
송주현,정진영,강용구,이한용,손문익,서상일 대한골절학회 2003 대한골절학회지 Vol.16 No.3
목적: 골종양 환자나 외상, 골수염, 인공관절 치환술 등의 환자 등의 환자 치료에 많이 사용하는 장관골의 동종 이식에 대한 PRP (Platelet-Rich Plasma)의 효과를 토끼를 이용한 실험으로 알아보고자 하였다. 대상 및 방법: 20마리의 토끼를 대상으로 각각에 일련번호를 붙이고, 각 토끼의 양측 척골에 약 2㎝ 길이의 골편을 얻어 장관골 결손을 만들고 동시에 동종 장관골을 얻어, 홀수 토끼의 척골 골편을 짝수 토끼의 골결손 분위에 이식하고, 반대로 짝수 토끼의 척골 골편을 홀수 토끼의 골결손 분위에 이식하였다. 그 후 각 토끼의 좌측 척골 이식 부위에는 아무런 처치를 하지 않고 대조군으로 삼고, 우측 척골 이식부에는 PRP 0.7cc를 처치하여 실험군으로 삼았다. 술 후 0, 4, 8, 12주에 골이식부에 대한 방사선 촬영을 통하여 골유합 성적을 평가 비교하였다. 결과: 실험군의 척골 분절 결손부에서는 대조군에서보다 동종 분절골 이식부의 골유합이 방사선학적으로 향상된 것을 관찰 할 수 있었다. 결론: 동종 장관골 분절 이식시 PRP를 병용하여 사용할 경우 더욱 효과적인 신생조직 형성을 유도할 수 있으며, 임상에도 유용하게 적용할 수 있으리라 사료된다. Purpose: The purpose of this study was to evaluate the effect of Platelet-Rich Plasma(PRP) on the healing of the allograft for the treatment of the segmental bone defect of the ulna in Rabbits. Materials and Methods: About 2 ㎝-sized segmental bone defects were created on both ulna of twenty rabbits. The rabbits were divided into two groups, even and odd number groups after numbering them from 1 to 20. The segmental bone from the odd numbered animal was transplanted to the even numbered animal, and the even numbered to the odd numbered. The left side of the ulna was grafted with a segmental allograft only. The right side of the ulna was grafted with a segmental allograft and 0.7cc of PRP. Radiographs obtained at 0, 4, 8, and 12 weeks postoperatively were graded for radiologic union. Result: The use of the combination of PRP and segmental allograft demonstrated improved healing on radiographic study compared with that demonstrated after use of allograft alone. Conclusion: The results of the study suggests that the use of the combination of PRP and segmental allograft can be considered as an alternative method to manage the segmental defect of the long bone.
열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구
배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2
Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.
Approximate Controllability for Semilinear Neutral Differential Systems in Hilbert Spaces
Jeong, Jin-Mun,Park, Ah-Ran,Son, Sang-Jin Department of Mathematics 2021 Kyungpook mathematical journal Vol.61 No.3
In this paper, we establish the existence of solutions and the approximate controllability for the semilinear neutral differential control system under natural assumptions such as the local Lipschitz continuity of nonlinear term. First, we deal with the regularity of solutions of the neutral control system using fractional powers of operators. We also consider the approximate controllability for the semilinear neutral control equation, with a control part in place of a forcing term, using conditions for the range of the controller without the inequality condition as in previous results.
Lee, Jeong-Sik,Jang, Deok-Jin,Lee, Nuribalhae,Ko, Hyoung-Gon,Kim, Hyoung,Kim, Yong-Seok,Kim, Byungwoo,Son, Junehee,Kim, Sung Hyun,Chung, Heekyoung,Lee, Mun-Yong,Kim, Woon Ryoung,Sun, Woong,Zhuo, Min,A The Society 2009 The Journal of neuroscience Vol.29 No.26
<P>The cAMP cascade and vascular endothelial growth factor (VEGF) are critical modulators of depression. Here we have tested whether the antidepressive effect of the cAMP cascade is mediated by VEGF in the adult hippocampus. We used a conditional genetic system in which the Aplysia octopamine receptor (Ap oa(1)), a G(s)-coupled receptor, is transgenically expressed in the forebrain neurons of mice. Chronic activation of the heterologous Ap oa(1) by its natural ligand evoked antidepressant-like behaviors, accompanied by enhanced phosphorylation of cAMP response element-binding protein and transcription of VEGF in hippocampal dentate gyrus (DG) neurons. Selective knockdown of VEGF in these cells during the period of cAMP elevation inhibited the antidepressant-like behaviors. These findings reveal a molecular interaction between the cAMP cascade and VEGF expression, and the pronounced behavioral consequences of this interaction shed light on the mechanism underlying neuronal VEGF functions in antidepression.</P>
R&E 탐구 과정 검토를 위한 SECE 컨설팅 모형의 제안 및 적용
문지영(Mun, Jiyeong),김성원(Kim, Sung-Won),김미영(Kim, Mi-Young),문공주(Mun, Kongju),손서진(Son, Seojin),이지선(Lee, Jisun),정지현(Jeong Jihyun),황요한(Hwang, Yohan) 학습자중심교과교육학회 2018 학습자중심교과교육연구 Vol.18 No.2
R&E(Research and Education) 활동은 학생이 스스로 과학 탐구를 수행하는 자기주도적 연구 활동이다. 자기 주도적 탐구 과정에는 연구팀의 연구 과정을 점검하고 컨설팅을 제공해주는 전문가, 즉 컨설턴트의 지원이 포함된다. 본 연구에서는 R&E 활동에서 연구팀의 연구개선을 위한 컨설팅 지원을 목적으로, R&E 탐구 과정 검토를 위한 SECE 컨설팅 모형을 제안하였다. 컨설팅 모형은 상황제시, 문제탐색, 문제해결을 위한 추진전략 제안, 실행방법 설계의 4개의 전략을 포함하고 있으며, 각 전 략을 기반으로 컨설팅 가이드라인을 개발하였다. 이를 STEAM R&E의 온라인 컨설팅에 적용하여 컨설팅 내용을 분석하였다. 또한 컨설턴트와 지도교사의 인식조사를 실시하여 컨설턴트의 자문활동에 미친 영향과 연구팀의 연구개선에의 효과를 알아 보았다. 연구 결과, 컨설턴트는 각 전략별 하위 문항에 따라 연구 과정을 검토하였으며, 연구팀이 지닌 문제점과 어려움을 파악하여 그에 대한 피드백을 제공하였다. 컨설턴트들은 본 컨설팅 모형이 연구팀의 연구내용을 파악하고 검토하는 데에 유용하 다고 인식하였고, 지도교사들도 컨설팅 내용이 연구개선에 효과적이었다고 인식하고 있음이 나타났다. 연구 결과를 바탕으로 R&E 활동에서 컨설팅 가이드라인의 활용 가능성과 컨설턴트의 역할에 대해 논의하였다. Enhancing students’ inquiry skill has been one of the most important goals of science education. Through R&E (Research and Education) project, students experience self-directed research process. R&E activities involve the support of an expert group, or consultants. They review the research process and provides consulting services. In this study, we proposed a SECE consulting model for reviewing the R&E inquiry process in order to support the consulting activities that help students’ research activity. The SECE model includes four strategies: Scan, Explore, Create and Execute. A consulting guideline was developed for each strategy. We administered the guideline to STEAM R&E research team and 33 consultants. Through the online consulting, consultants reviewed research reports and provided consulting based on the consulting guideline. A total of 117 consulting results were collected. We also conducted an survey for consultants and teachers of the R&E team to investigate the effects of consulting guideline. The results showed that consultants reviewed the research process according to the detailed questions of SECE strategy and identified the difficulties and problems of the research team and the guideline helped consultants to provide feedback. The results of the survey revealed that consultants considered the SECE model useful in reviewing and assessing the research team’s work. Also, the participating teachers noted that the consulting results was effective in improving their research process. Based on the results, we proposed the availability of consulting guidelines and the role of consultants in R&E activities.